Clinical trials: Intensive Care Unit (ICU)
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Fungal Infection
The Impact of Rapid Diagnostic Methods in the Diagnosis of Fungal Infections in Intensive Care Units of Assiut University Hospital
The diagnosis of invasive fungal disease remains challenging in the clinical laboratory. The use of matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) for the identification of filamentous…
- Trial name
- NCT05876962
- Volunteers
- 100 people
- Sponsor
- Assiut University
Infant, Premature, Diseases, Premature Birth of Newborn
Elevated Midline Positioning During Diaper Change in Preterm Infants
Diaper changing is one of the most frequent routine care procedures in the neonatal intensive care unit (NICU) and is known to cause physiological instability and behavioral stress responses in preterm infants.
- Conditions
- Infant, Premature, Diseases, Premature Birth of Newborn, Pain
- Trial name
- NCT07865897
- Testing
- 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
Clinical Implementation, Standardized Tube Feeding Care
Clinical Implementation of the Group Standard for Enteral Feeding Care in Critically Ill Children
This study aims to evaluate the feasibility and effectiveness of the " Standard for Enteral Feeding Care in Critically Ill Pediatric Patients " (T/CNAS 45-2024) in a multicenter setting.
- Conditions
- Clinical Implementation, Standardized Tube Feeding Care, Enteral Nutrition
- Trial name
- NCT07441746
- Testing
- Evidence-based tube feeding care, Routine Enteral Feeding Care
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Children's Hospital of Fudan University
Premature Birth, Premature
Post-Care Positioning and Comfort in Late Preterm Infants
This study examined the comfort of late preterm infants (born at 34 0/7 to 36 6/7 weeks of gestation) placed in four positions after routine nursing care in a neonatal intensive care unit.
- Trial name
- NCT07881653
- Testing
- Sequential post-care positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Water-Electrolyte Imbalance, Intensive Care Units
Fluid Overload and Pulmonary Function
Esophageal atresia is a rare but severe malformation, and it requires early surgery. Coloesophagoplasty is surgical repair of the esophageal with an isoperistaltic transverse colon graft.
- Conditions
- Water-Electrolyte Imbalance, Intensive Care Units, Pediatric, Critical Illness
- Trial name
- NCT05129930
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Pirogov Russian National Research Medical University
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Neonatal Respiratory Distress
Lung Ultrasound in Neonatal Intensive Care Units
Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .
- Trial name
- NCT06372951
- Testing
- Ultrasound
- Volunteers
- 132 people
- Sponsor
- Assiut University
Ventilator Associated Pneumonia ( VAP)
Pre-clinical Diagnosis Using Integrated Microbial and Host Response Signatures to Improve Outcomes From Ventilator-associated Pneumonia in Critically Ill Children
Ventilator-associated pneumonia (VAP), defined as pneumonia occurring 48 hours after initiation of invasive mechanical ventilation, is insidious in onset and severe in consequence.
- Trial name
- VAP-Dx (NCT07026656)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Cambridge
Pediatric Respiratory Diseases, Respiratory Failure
Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.
The purpose of this study is to determine the utility of point-of-care lung ultrasound (POC-LUS) in identifying the etiology of acute respiratory failure in pediatric patients admitted to the pediatric intensive care unit.
- Trial name
- NCT03744169
- Testing
- Lung ultrasound, Clinical exam, Chest x-ray
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Wisconsin, Madison
Oral Feeding Outcomes, Growth
Impact of Implementing an Infant Driven Feeding Program on Oral Feeding and Growth Outcomes of Medically Fragile Infants in the Neonatal ICU (NICU)
The specific aim of this pre-post trial is to compare data regarding oral feeding, length of stay, and growth outcomes of 100 NICU infants to these same outcomes following the implementation of a developmentally supportive…
- Conditions
- Oral Feeding Outcomes, Growth, Length of NICU Stay
- Trial name
- NCT01666457
- Testing
- SOFFI
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Medical Errors, Electronic Medical Records
Pictographs for Preventing Wrong-Patient Errors in NICUs
Newborns in the neonatal intensive care unit (NICU) are at high risk for wrong-patient errors. Effective 2019, The Joint Commission requires that health systems adopt distinct methods of newborn identification as part of its…
- Trial name
- NCT03960099
- Testing
- Pictograph in Banner and Verification Alert
- Where
- 4 sites in United States
- Volunteers
- 6,250 people
- Sponsor
- Columbia University
Maternal Depression
Problem Solving Education and Neonatal Intensive Care Unit (NICU) Mothers
Premature infants are born at substantial risk for poor health and developmental outcomes, which commonly include hearing and vision problems, developmental delays, and poor school performance.
- Trial name
- Project Solve (NCT01214967)
- Testing
- Problem Solving Education
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Boston Medical Center
Pediatrics, Intensive Care Unit
Asia Pediatric Intensive Care Epidemiology and Outcomes Study
The overall objective of this study is to improve the standard of care of critically ill pediatric patients. The specific aims are to describe the clinical profile and outcomes of all admissions to Asian pediatric ICUs, determine…
- Conditions
- Pediatrics, Intensive Care Unit, Critical Illness
- Trial name
- AsiaPedIC (NCT06481644)
- Where
- 2 sites in Singapore, Thailand
- Volunteers
- 10,000 people
- Sponsor
- KK Women's and Children's Hospital
Burns
Study on the Infection Risk of Long Dwell Period Catheters in High Risk Intensive Care Unit (ICU) Patients
This is an evaluation of the use of silver impregnated catheters in burn patients to reduce catheter colonisation compared to the standard central venous catheter without antiseptic activity.
- Trial name
- NCT00136097
- Testing
- Placement of a silver impregnated central venous catheter
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- University Hospital, Ghent
Mechanical Ventilation Complication, Pediatric ALL
Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.
Critically ill children treated with invasive mechanical ventilation (iMV) in a paediatric intensive care unit (PICU) may suffer from complications leading to prolonged duration of ventilation and PICU stay.
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04589910
- Testing
- diaphragm thickness and thickening fraction
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Congenital Heart Disease
Effect of a High Density Formula on Growth and Safety in Congenital Heart Disease Infants
The purpose of this study is to explore the effects of high density formula in early postoperative infants with congenital heart disease and to assess its safety.
- Trial name
- CHD (NCT02389491)
- Testing
- normal density formula (Necocate), high density formula(Infatrini)
- Volunteers
- 64 people
- Sponsor
- Children's Hospital of Fudan University
Infant, Newborn, Pharmacoepidemiology
Commonly Used Medicines On Neonatal Units in the UK
This retrospective analysis of drug utilisation data aims to study the patterns of use of medicines in neonatal units in the UK from 2010 to 2017.
- Conditions
- Infant, Newborn, Pharmacoepidemiology, Intensive Care Units, Neonatal
- Trial name
- COMMON (NCT03773289)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 642,729 people
- Sponsor
- University of Nottingham
Neonatal Convulsions, Newborn Seizure Disorders
Clinical Profile And Outcomes Of Neonatal Convulsions In The Neonatal Intensive Care Unit At Assiut University Children's Hospital
Neonatal convulsions are seizures that occur during the first 28 days of a newborn's life. They are considered a medical emergency and often indicate an underlying problem in the brain, such as lack of oxygen at birth…
- Conditions
- Neonatal Convulsions, Newborn Seizure Disorders, Seizures
- Trial name
- NCT07274410
- Testing
- Management of Neonatal Convulsions
- Volunteers
- 139 people
- Sponsor
- Assiut University
Cardiopulmonary Arrest, Cardiac Arrest
Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation
Cardiac arrest has a very poor prognosis, especially with prolonged efforts at resuscitation, and unfortunately, survivors are often severely neurologically impaired.
- Trial name
- Vasopressin (NCT00628550)
- Testing
- Vasopressin, Epinephrine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Texas Southwestern Medical Center