Clinical trials: Infertility, Female
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility
Physiotherapy Treatment for Uterine Blood Flow Improved Dimensional Ultrasound Evaluated With Angiography
Ivanovski shows that by studying the vascular impedance can calculate the optimal uterine receptivity in IVF. A reduced vascular resistance and increased blood flow rate improves the chance of pregnancy. Dr. Luis T.
- Trial name
- NCT02437435
- Testing
- Reproductive Technique Gimilio
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- University of Valencia
Infertility,Female
Recombinant LH Supplementation Timing Strategies (From Day 1 or Day 6) to a Standard GnRH Agonist Long Protocol in Subsequent COS Cycle of Older Patients With Unexpected Poor or Suboptimal Ovarian Response
A randomized, controlled, pilot study, for Patients ≥ 35 years and < 40 years old with sufficient ovarian reserve parameters (AFC≥ 5), but showed an unexpected poor or suboptimal ovarian response(defined as ≤ 9 retrieved oocytes…
- Trial name
- NCT04178135
- Testing
- rLH
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility, Intellectual Disability
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
Chromosomal aberrations are major causes of developmental disorders (Intellectual disability (ID), multiple congenital anomalies (MCA), autism spectrum disorders (ASD)) as well as reproductive disorders (RD) in particular…
- Conditions
- Infertility, Intellectual Disability, Malformation, Miscarriage
- Trial name
- CHROMAPS (NCT05290051)
- Testing
- Optical Genome Mapping (Bionano®), Longread sequencing (Nanopore®)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Infertility, Infertility, Female
Follicular Fluid Fetuins in in Vitro Fertilization
This study aims to investigate whether follicular fluid concentrations of fetuin A and fetuin B are associated with the clinical pregnancy and live birth rates in in vitro fertilization (IVF) cycles.Twenty-nine women with poor…
- Trial name
- NCT04201847
- Testing
- Serum test
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Samsun Education and Research Hospital
Cancer, Hematologic Disorder
Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis/Treatment
The purpose of this research is to obtain ovarian tissue from female participants who will receive therapy which is expected to result in a loss or impairment of ovarian function and/or infertility and wish to preserve (freeze)…
- Conditions
- Cancer, Hematologic Disorder, Rheumatologic Disorder, Infertility
- Trial name
- NCT02678910
- Testing
- Ovarian Cryopreservation
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Vlad Radulescu
Obesity, Childhood, Lifestyle Intervention
Obesity-fertility Cohort Study: Protocol for the Assessment of Children Aged 6-12 Years and Their Mothers
Maternal preconception obesity and adverse gestational metabolic health increase the risk of childhood obesity in offspring. A group of investigators from Université de Sherbrooke therefore developed a lifestyle intervention…
- Conditions
- Obesity, Childhood, Lifestyle Intervention, Preconception Care
- Trial name
- NCT06402825
- Testing
- Fit-for-Fertility program
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Male Infertility, Female Infertility
IMSI in Couples With Previous Implantation Failures
There is a lack of clarity regarding the justification to instruct the couple to shift from intracytoplasmic sperm injection (ICSI) to intracytoplasmic morphologically selected sperm injection (IMSI).
- Trial name
- NCT02107521
- Testing
- Intracytoplasmic morphologically selected sperm injection, Intracytoplasmic sperm injection
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Sapientiae Institute
Infertility, Female
Evaluation of Different Culture Media for in Vitro Fertilization
Under in vivo conditions, human gametes and embryos are exposed to fluids in the fallopian tubes, where fertilization occurs, and in the uterus, the site of embryonic implantation.
- Trial name
- NCT05676515
- Testing
- culture media
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Endocrine Disorders of Female Reproductive System, Secondary Infertility
Preservation of Ovarian Tissue and Chemo-Radiotherapy
The purpose of this study is to assess the results of ovarian tissue freezing, such as resumption or initiation of menses (menstruation: the discharge of blood and tissue from the uterus that happens about every 4 weeks in…
- Conditions
- Endocrine Disorders of Female Reproductive System, Secondary Infertility, Infertility Involuntary
- Trial name
- NCT02429349
- Testing
- surgery
- Where
- 7 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Tennessee
CHLAMYDIA INFECTIONS
Immunopathogenesis of Chlamydia
Sexually transmitted Chlamydia trachomatis infections are a widespread public health concern due to their prevalence and potentially devastating reproductive consequences, including pelvic inflammatory disease, infertility, and…
- Trial name
- NCT00607659
- Testing
- No intervention, only observational
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Female Infertility
The Embryologist's Impact on Blastocyst Vitrification and Thawing
The goal of this monocentric retrospective observational study is to analyse, for the first time in literature, the role of the embryologist who freezes and thaws the embryos.
- Trial name
- NCT06220227
- Testing
- vitrification and thawing procedures
- Where
- Italy
- Volunteers
- 6,800 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Infertility
Hyaluronic Acid-enriched Transfer Medium in Single Blastocyst Transfer
The purpose of this study is to compare the live birth rates of high concentration of Hyaluronic Acid (0.5 mg/ml) transfer medium (EmbryoGlue®) to those containing low Hyaluronic Acid concentrations (0.125 mg/ml) (G2 medium) in…
- Trial name
- NCT06492785
- Testing
- High Hyaluronic Acid concentrations (0.5 mg/ml), Low Hyaluronic Acid concentrations (0.125 mg/ml)
- Where
- China
- Volunteers
- 858 people
- Sponsor
- Northwest Women's and Children's Hospital, Xi'an, Shaanxi
Women in the Reproductive Age Group, Undergoing Laparoscopy for Pelvic Pain and/or Infertility
Endometrial Biopsy as Diagnostic Method for Endometriosis and Endometrioma
Our aim was to evaluate the efficacy of examining endometrial biopsy specimens for nerve fibers as a diagnostic test for endometriosis and endometrioma in a double-blind comparison with diagnostic laparoscopy.
- Conditions
- Women in the Reproductive Age Group, Undergoing Laparoscopy for Pelvic Pain and/or Infertility, Not Currently Receiving Hormonal Treatment for at Least 3 Months Prior to Laparoscopy.
- Trial name
- NCT01022372
- Testing
- Endometrial biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Infertility, Female
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome
Polycystic ovary syndrome accounts for the vast majority of anovulatory symptoms and hyperandrogenism in women. The diagnosis of Polycystic ovary syndrome has life-long implications, with increased risk for infertility, metabolic…
- Trial name
- NCT03135301
- Testing
- letrozole plus metformin, letrozole
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Infertility, Female
Intracervical Anasthesia in Outpatient Hystroscopy, Can Procedure be Completed Diagnostic and Therapeutic With no Need to General Anaesthesia
Single blind randomized controlled study in which 80 patients coming for hystroscopy due to multiple indication as infertility, AUB and missed IUD were assigned for our study.
- Trial name
- NCT03747692
- Testing
- study group, control group
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endometriosis, Pelvic Pain
Machine Learning for Early Diagnosis of Endometriosis(MLEndo)
The project aims to create a large prospective data bank using the Lucy medical mobile application and collect and analyze patient profiles and structured clinical data with artificial intelligence.
- Conditions
- Endometriosis, Pelvic Pain, Infertility, Female
- Trial name
- MLEndo (NCT06147687)
- Testing
- Self reported data collection
- Where
- 2 sites in Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Anti-Müllerian Hormone, Polycystic Ovarian Syndrome
Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements
This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following: 1.
- Conditions
- Anti-Müllerian Hormone, Polycystic Ovarian Syndrome, Premature Ovarian Insufficiency, Fertility Issues
- Trial name
- NCT05858307
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Chinese University of Hong Kong
Infertility, Female, Sexual Intercourse
Sex or no Sex: That is the Question.
This study aims to evaluate the impact of sexual intercourse and orgasm in the 72 hrs following embryo transfer of blastocysts on the clinical pregnancy rate.
- Trial name
- NCT04880590
- Testing
- Sex intercourse
- Where
- Spain
- Volunteers
- 412 people
- Sponsor
- Fundación Santiago Dexeus Font