Clinical trials: Implementation Research
Accidental Injuries, Global Child Health
The P-KIDs CARE Health Systems Intervention in Tanzania
The objective of the proposed research is to develop and pilot a locally-relevant, multicomponent intervention to streamline the triage process (e.g.
- Conditions
- Accidental Injuries, Global Child Health, Pediatric Emergency Medicine, Public Health System Research
- Trial name
- P-KIDs CARE (NCT06075108)
- Testing
- P-KIDs CARE
- Where
- Tanzania
- Volunteers
- 284 people
- Sponsor
- University of Utah
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
Emergencies
Non-medical Practitioner Workforce in the Urgent and Emergency Care System Skill-mix in England
This study will explore the result of different skill-mix in ED/UTCs in England, to make recommendations about the best balance. Patient and public involvement (PPI) representatives have helped design the study.
- Trial name
- SKILLmix-ED (NCT04770766)
- Testing
- Non-medical practitioners
- Where
- 2 sites in United Kingdom
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Kingston University
Respiratory Insufficiency Syndrome of Newborn
CPAP vs NIPPV: A COMPARATIVE EFFECTIVENESS RESEARCH
Aim: Investigators aim is to conduct two complementary and concurrent CER projects using a pragmatic clinical trial design and registry-based RWD to identify the optimal respiratory management practices for extremely preterm…
- Trial name
- NCT04075123
- Testing
- CPAP
- Where
- Canada
- Volunteers
- 1,829 people
- Sponsor
- Canadian Neonatal Network
Understanding of Consent in Clinical Research, Implementation of Consent in Clinical Research
Facilitating Learning Health Care (LHC) and Neonatal Research: Effects of a Brief Introductory Discussion Between a Neonatologist and the Parents of Eligible Infants
The primary purpose of this pilot quality improvement study is to assess the impact of a brief introductory discussion about Learning Health Care (LHC) and clinical research between a neonatologist and the mothers (and the…
- Trial name
- NCT05541536
- Testing
- Consultation meeting, Pamphlet, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Low Birth Weight
Kangaroo Mother Care Implementation Research for Accelerating Scale-up
The implementation research project aims to develop and evaluate models for scaling up KMC in health facilities across India and Ethiopia and thereby develop effective approaches to achieve high population coverage
- Trial name
- NCT03506698
- Testing
- Kangaroo Mother Care (KMC)
- Where
- 3 sites in Ethiopia
- Volunteers
- 3,804 people
- Sponsor
- Rajiv Bahl
Nurse's Role
Development of Electronic Continuing Professional Development for Indonesian Clinical Nurses
The goal of this clinical trial is to test a e-CPD prototype device for feasibility as it is applied within the clinical nursing setting in Level II clinical nurses in Indonesia.
- Trial name
- e-CPD (NCT06047652)
- Testing
- e-CPD user testing
- Volunteers
- 7 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Cysticercosis
EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso
This is a pre-post randomized community-based controlled trial aimed at estimating the effectiveness of an educational package developed using PRECEDE PROCEED to reduce the cumulative incidence of Taenia solium cysticercosis in…
- Trial name
- EFECAB (NCT03095339)
- Testing
- Educational package
- Where
- Burkina Faso
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Data Accuracy, Agency
Empowerment Training for Personal Agency Development of Primary Health Care Workers
This study evaluates an Empowerment Agency Training (EAT) intervention within the SPHERES programme that aims to strengthen personal agency among workers in primary healthcare centers (Puskesmas) in Indonesia.
- Conditions
- Data Accuracy, Agency, Burnout, Service Evaluation
- Trial name
- NCT07509931
- Testing
- Empowerment Agency Training (EAT)
- Where
- 2 sites in Indonesia
- Volunteers
- 200 people
- Sponsor
- Oxford University Clinical Research Unit Indonesia
Maternal and Child Health, Health Service Utilization
Integrated Community Based Health Systems Strengthening in Northern Togo
The general objective of this study is to optimize implementation and assess effectiveness of the integrated facility and community-based health systems strengthening (ICBHSS) model in four Northern Togo districts, using the…
- Trial name
- ICBHSS-Togo (NCT03694366)
- Testing
- ICBHSS model
- Where
- Togo
- Volunteers
- 7,600 people, healthy volunteers welcome
- Sponsor
- Integrate Health
Neonatal Resuscitation, Delivery Room Resuscitation
Supraglottic Airway for Resuscitation Trial
This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on…
- Conditions
- Neonatal Resuscitation, Delivery Room Resuscitation, Positive Pressure Ventilation, Infant, Newborn
- Trial name
- SUGAR (NCT07150923)
- Testing
- Enhanced Standard of Care ("Enhanced"), Enhanced Standard of Care ("Enhanced-Plus")
- Where
- 30 sites in United States
- Volunteers
- 36,503 people
- Sponsor
- Children's Hospital of Philadelphia
Malaria Asymptomatic Parasitaemia, Malaria Falciparum
Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administration in High Endemic Communities in the Eastern Region of Ghana
Previous malaria control studies in Ghana have shown that community-wide approaches can substantially reduce malaria infections.
- Conditions
- Malaria Asymptomatic Parasitaemia, Malaria Falciparum, Malaria Infection, Malaria Transmission
- Trial name
- NCT07389057
- Testing
- DHAP, Single low dose PQ
- Where
- Ghana
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Healthy
Implementation of Job Rotation for the Development of Nursing Competencies and the Improvement of Organizational Health in a Department of Cardiovascular Sciences: A Research Protocol
This prospective, monocentric observational study aims to evaluate the implementation of a Job Rotation (JR) program in the Department of Cardiovascular Sciences at Fondazione Policlinico Universitario A. Gemelli IRCCS.
- Trial name
- JR_01 (NCT06987487)
- Testing
- Job Rotation Program, No Job Rotation (Standard Care)
- Where
- Italy
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Telemedicine Usage, Teleconsultation Usage
Implementation Strategy and Systemic Effects of Routine Telemedical Care in Prehospital Emergency Medicine
In two research projects a comprehensive prehospital telemedicine system was developed and general feasibility as well as impact on guideline adherence were evaluated.
- Conditions
- Telemedicine Usage, Teleconsultation Usage, Emergency Medical Service Missions
- Trial name
- NCT04127565
- Volunteers
- 51,649 people
- Sponsor
- RWTH Aachen University
Nutrient Deficiency
Antenatal Multiple Micronutrient Supplementation (MMS) in Indonesia
The objective of this research is to understand how antenatal multiple micronutrient supplements (MMS) can be effectively implemented and scaled within the Indonesian national health system context to support improved maternal…
- Trial name
- NCT06225791
- Testing
- MMS (90x2) + BCC or expanded BCC, MMS (180x1) + BCC or expanded BCC
- Where
- Indonesia
- Volunteers
- 5,384 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Team-effectiveness Research, School-based Interventions
Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD
The proposed project aims to integrate team-based implementation strategies with an established school-based intervention for children with ADHD, the Collaborative Life Skills Program (CLS), to enhance its implementation and…
- Conditions
- Team-effectiveness Research, School-based Interventions, Attention Deficit/ Hyperactivity Disorder, Implementation Science
- Trial name
- NCT06180681
- Testing
- Team-Enhanced Collaborative Life Skills Program, Standard Collaborative Life Skills Program
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
HIV/AIDS, Tuberculosis
Choice Architecture Based TB Preventive Therapy Prescribing
Background: Clinical guidelines and policies often fail to achieve high levels of delivery of intended clinical interventions. The difference in what investigators know works and what is actually delivered at the clinic-level to…
- Trial name
- CAT (NCT04466293)
- Testing
- Choice Architecture
- Where
- 3 sites in Malawi, Mozambique and 1 more
- Volunteers
- 57 people
- Sponsor
- Johns Hopkins University
Family Research
Addressing Mental Health Disparities in Refugee Children
The proposed study will employ a cross-cultural Community Based Participatory Research (CBPR) approach to build from prior needs assessments and mixed-methods research to evaluate the effectiveness of the Family Strengthening…
- Trial name
- NCT03796065
- Testing
- FSI-R Treatment
- Where
- 2 sites in United States
- Volunteers
- 354 people
- Sponsor
- Boston College
Suicide
Army-SPRING Army-Suicide Prevention Research
Every unit in the Connecticut Army National Guard has a Suicide Intervention Officer to provide suicide intervention education awareness for their unit, monitor for soldiers in crisis and connect soldiers with helping resources…
- Trial name
- NCT06547008
- Testing
- Army-SPRING, Risk Reduction Group (Control)
- Where
- 3 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Malaria
Factors Influencing Adoption of a Novel Malaria Treatment in Côte d'Ivoire, Ghana, and Rwanda
This non-interventional qualitative study will examine factors that influence the adoption of a novel malaria treatment in Côte d'Ivoire, Ghana, and Rwanda.
- Trial name
- NCT07896746
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals