Clinical trials: Idiopathic
Erector Spinae Block, Analgesia
Ultrasound Guided Bilateral Erector Spinae Block as Analgesia for Adolescent Idiopathic Scoliosis Correction
Scoliosis is a structural, tridimensional deformity of the spine. Characterized by lateral curvature and rotation of the vertebrae with functional limitations and cosmetic problems, idiopathic scoliosis, which accounts for 75% to…
- Conditions
- Erector Spinae Block, Analgesia, Scoliosis Idiopathic
- Trial name
- NCT04336046
- Testing
- erector spinae block, normal saline, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Idiopathic Juvenile Arthritis
Biomarkers in Idiopathic Juvenile Arthritis
Juvenile idiopathic arthritis (JIA) is the most common form of arthritis in children. The etiology is unknown. Several types of arthritis fall under the JIA heading.
- Trial name
- NCT02343770
- Testing
- blood sample for identifying biomarkers
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Growth Disorder, Idiopathic Short Stature
Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature
This trial is conducted in Asia. The aim of this trial is to evaluate the efficacy and safety of recombinant human growth hormone (hGH) in subjects with idiopathic short stature in Korea.
- Trial name
- NCT01778023
- Testing
- somatropin
- Where
- 8 sites in South Korea
- Volunteers
- 54 people
- Sponsor
- Novo Nordisk A/S
Scoliosis; Adolescence
A New Spinal Orthosis for Adolescent Idiopathic Scoliosis
The new device with digital technology provides a new avenue to enable clinicians to communicate wirelessly with the imbedded core system such that they can adjust the electrical stimulation parameters and retrieve the…
- Trial name
- NCT03825159
- Testing
- Spinal Orthosis with an Integrated System of Electric Surface Stimulation and Heat Sensing, spinal orthosis
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Changhua Christian Hospital
Idiopathic Increased Femoral Anteversion
The FDR (Femoral Derotaton) Trail.
Femoral derotational osteotomy is the gold standard to correct symptomatic patients with increased femoral AV. There is no clear evidence in the literature supporting which surgical technique or implant that should be used.
- Trial name
- FDR (NCT04086368)
- Testing
- Adolescent Lateral Entry Femoral Nail, Pediatric LCP Hip Plate System
- Where
- Norway
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Scoliosis, Spondylolisthesis
Effect of Pregabalin on Immediate Post-operative and Longterm Pain
This study aims to evaluate the incidence of longterm pain after spinal fusion surgery in children and adolescents. In the second part of the study a randomized double-blind clinical trial will be conducted.
- Trial name
- NCT02464813
- Testing
- Pregabalin, Sugar pill, Oxycodone
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Adolescent Idiopathic Scoliosis
Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion
Prospective, randomized control trial To determine if oral caffeine decreases the frequency of opioid demand in children with adolescent idiopathic scoliosis after their spinal fusion surgery To compare pain scale ratings, number…
- Trial name
- NCT04950660
- Testing
- Caffeine Tablet
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Children's Mercy Hospital Kansas City
Scoliosis; Adolescence, Spinal Curvatures
Effect of PSSE on Spine Reposition Sensation in Scoliosis
The main aim of the investigator's study is to investigate the effect of Physiotherapeutic Scoliosis-Specific Exercises (PSSE) on spine joint reposition sense and also to investigate the effect of PSSE on vertebral rotation…
- Conditions
- Scoliosis; Adolescence, Spinal Curvatures, Proprioception, Physiotherapy
- Trial name
- PSSE (NCT04215497)
- Testing
- PSSE
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoporosis
Treatment of Childhood Osteoporosis With Alendronate (Fosamax)
Bones grow and stay strong through a continuous process of formation (building) and resorption (break down). When more bone is formed than resorbed, the density (level of calcium) in bone increases and the bones become stronger.
- Trial name
- NCT00001720
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Ultra-short-term, Iron Deficiency Anemia
Effect of Ultra-short-term Treatment of Patients With Iron Deficiency or Anemia Undergoing Adolescent Scoliosis Correction
Scoliosis is a condition in which there is curvature of the spine occurring in the lateral plane. It occurs in structural forms, characterized by a fixed curve, and "functional" forms, characterized by a flexible or correctable…
- Conditions
- Ultra-short-term, Iron Deficiency Anemia, Scoliosis Idiopathic
- Trial name
- NCT04343170
- Testing
- ferric carboxymaltose , α erythropoietin, vitamin B12, oral folic acid
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Chronic Idiopathic Urticaria
A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1)
The study is a global Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of omalizumab administered subcutaneously as an add-on therapy for the treatment…
- Trial name
- NCT01292473
- Testing
- Omalizumab
- Where
- 61 sites in United States, Denmark and 6 more
- Volunteers
- 323 people
- Sponsor
- Genentech, Inc.
Juvenile Idiopathic Arthritis, Gingivitis
Clinical and Biochemical Evaluation of Dental and Periodontal Conditions in Children With Juvenile Idiopathic Arthritis
Aimed to be done in the planned thesis to evaluate the dental and periodontal health of patients with newly diagnosed JIA and healthy-periodontal problems with cytokines from saliva and oxidative stress markers non-invasively…
- Conditions
- Juvenile Idiopathic Arthritis, Gingivitis, Decay, Dental
- Trial name
- NCT05217277
- Testing
- Humans ELISA kits
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Marmara University
Parkinson Disease
Continuous Delivery of Levodopa in Patients With Advanced Idiopathic Parkinsons Disease - Cost-benefit
An open, observational health economic study to estimate marginal cost and health consequences of replacing conventional Parkinsons disease therapy with intraduodenal levodopa administered continuously
- Trial name
- NCT00272688
- Testing
- Levodopa (drug), intraduodenal administration
- Where
- 2 sites in Norway
- Volunteers
- 10 people
- Sponsor
- University Hospital, Akershus
Asthma, Chronic Obstructive Pulmonary Disease
A Study of Patients With Chronic Disease
TARGET-RWE is a 10-year, international, longitudinal, observational study of patients with chronic disease designed to specifically address important clinical questions that remain incompletely answered from registration trials.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis, IPF
- Trial name
- NCT04263727
- Where
- 5 sites in United States
- Volunteers
- 579 people
- Sponsor
- Target PharmaSolutions, Inc.
Scoliosis, Spine Deformity
Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis
Idiopathic scoliosis of developmental age (AIS) is the most vertebral deformity in the adolescent population, with a prevalence of 1-3%.
- Conditions
- Scoliosis, Spine Deformity, Adolescent Idiopathic Scoliosis
- Trial name
- BS23 (NCT06396286)
- Testing
- single rod
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cancer
Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation
RATIONALE: Antivirals such as valacyclovir act against viruses and may be effective in preventing cytomegalovirus. It is not yet known if valacyclovir is effective in preventing cytomegalovirus in patients undergoing stem cell…
- Trial name
- NCT00045292
- Testing
- acyclovir, acyclovir sodium, valacyclovir
- Where
- 6 sites in United States
- Sponsor
- Fred Hutchinson Cancer Center
Scoliosis Idiopathic Adolescent
Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) is a curvature of the spine that occurs in 1-2% of otherwise healthy children, and requires corrective surgery, posterior spinal fusion (PSF) in ~10% of cases.
- Trial name
- NCT03539770
- Testing
- Posterior spinal fusion
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Temporomandibular Joint Disorder
Effect of Functional Treatment on Mandibular Asymmetric Growth
Temporomandibular joint (TMJ) arthritis is known to alter the mandibular development in children diagnosed with juvenile idiopathic arthritis.
- Trial name
- NCT01113177
- Testing
- Distraction splint therapy
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Aarhus
Adolescent Idiopathic Scoliosis
Identification of Circulating microRNAs in Adolescent Idiopathic Scoliosis
The aim of the present study is to evaluate the expression of a large panel of microRNAs, already known and validated in other ortopedic pathologies and bone metabolism, in the plasma of Adolescent Idiopathic Scoliosis (AIS)…
- Trial name
- IMIRSA (NCT04746586)
- Testing
- Circulating MiRNA indentification
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Nephrotic Syndrome
Prednisolone Trial in Children Younger Than 4 Years
This study is a multicentric, randomized, parallel group, open label controlled trial of children age 1 year up to 4 years with new onset, idiopathic nephrotic syndrome.
- Trial name
- NCT03141970
- Testing
- Prednisolone
- Where
- 5 sites in United States, India
- Volunteers
- 170 people
- Sponsor
- All India Institute of Medical Sciences
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