Clinical trials: Hemodynamics
Hemorrhagic Shock, Pediatric Trauma
Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients
Pediatric trauma often leads to hemorrhagic shock, which reduces blood flow to the digestive tract and delays gastric emptying. This delay can cause fluid and food to remain in the stomach, increasing the risk of pulmonary…
- Conditions
- Hemorrhagic Shock, Pediatric Trauma, Delayed Gastric Emptying, Gastric Dysmotility
- Trial name
- NCT07810907
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hemodynamics Instability, Arrhythmias Cardiac
Low and Moderete Flow Anaesthesia on Haemodynamics
The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.
- Conditions
- Hemodynamics Instability, Arrhythmias Cardiac, Cerebral Oxygenation
- Trial name
- NCT06871371
- Testing
- Sevoflurane (Volatile Anesthetic), low- medium flow anesthetic machine
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Umraniye Education and Research Hospital
Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction
Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease
This study evaluates whether new flow parameters of the cardiac magnetic resonance imaging (MRI) allow evaluation of parameters for which usually invasive rigth-left heart catheterization are necessary.
- Conditions
- Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction, Fontan Circulation
- Trial name
- NCT07742046
- Testing
- Right-left heart catheterization in magnetic resonance imaging (MRI)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Tobias Rutz
Hemodynamic Instability
Role of Nebulized Dexmedetomidine in Blunting the Effects of Direct Laryngoscopy and Endotracheal Tube on Heart Rate and Blood Pressure.
The goal of this interventional study is to check the effectiveness of nebulized Dexmedetomidine in preventing the rise in blood pressure and heart rate in patients undergoing General Anesthesia.
- Trial name
- NCT06103721
- Testing
- Dexmedetomidine Injection [Precedex], Normal Saline
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Intrauterine Growth Restriction, Small-for-gestational Age
Ultrasound Evaluation of Fetal Hemodynamics and Perinatal Complications
In case of fetal weight below the 10th centile for gestational age, it is important to distinguish SGA and IUGR. SGA is defined as a fetal weight below the 10th centile.
- Trial name
- PTI'DOP (NCT03865628)
- Volunteers
- 1,200 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Coronavirus, SARS-CoV-2
Hemodynamic Characteristics of Patients With SARS-CoV-2
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a public health emergency of international concern.
- Conditions
- Coronavirus, SARS-CoV-2, COVID-19, Acute Respiratory Distress Syndrome
- Trial name
- PiCCOVID (NCT04337983)
- Testing
- Transpulmonary thermodilution, Echocardiography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Bicetre Hospital
Video-Assisted Thoracic Surgery
Hemodynamic and Inflammatory Responses in Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) for thoracic surgery is practical, has been shown to reduce postoperative discomfort, and has improved cosmetic results when compare to open thoracotomy.
- Trial name
- NCT02647775
- Testing
- multi-port VATS, single-port VATS
- Where
- Taiwan
- Volunteers
- 63 people
- Sponsor
- Chang Gung Memorial Hospital
Growth and Development
fMRI Study to Investigate Hemodynamic Changes in Brain Resulting From Supplementation of Bacopa Monnieri Extract and Multiple Micronutrient Supplementation.
The study will aim to compare the effects of a beverage powder fortified with multiple micronutrients and Bacopa monnieri extract (test product) to a non-fortified isocaloric beverage powder (control product) on cognitive…
- Trial name
- NCT02345187
- Testing
- Beverage powder fortified with Bacopa Monnieri Extract and Multiple Micronutrient supplementation, Non-fortified isocaloric beverage powder
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Pediatric Shock
Functional Hemodynamic Assessment in Shocked Patients in the Pediatric Intensive Care Unit
is to assess Functional hemodynamic status in shocked patients in the Pediatric Intensive Care Unit
- Trial name
- NCT06720493
- Testing
- echocardiographic assessment of shocked patients to fluid administration
- Volunteers
- 129 people
- Sponsor
- Assiut University
Medulloblastoma, Childhood, Survivorship
Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback
This study will evaluate a new way to help childhood medulloblastoma survivors improve their thinking and memory skills. Many survivors experience long term challenges with attention and working memory because of the tumor and…
- Trial name
- NCT07830134
- Testing
- rt fMRI Neurofeedback (DLPFC), rt fMRI Neurofeedback (PAC)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Jude Children's Research Hospital
Induction of General Anesthesia
Propofol Versus Sevoflurane for Induction of GA in Infants
This comparative study aims to investigate the haemodynamic safety profile for induction of general anesthesia in infants 3 months or less guided by electrical cardiometry parameters versus sevoflurane.
- Trial name
- NCT05105022
- Testing
- Propofol
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Anesthesia Intubation Complication
Co-induction Ketamine-propofol: Effects on Laryngeal Mask Airway Insertion Conditions in Children
Background: Large doses of propofol needed for induction and laryngeal mask (LM) insertion in children may be associated with hemodynamic sides effects.
- Trial name
- NCT03631875
- Testing
- Ketamine
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- University Hospital, Mahdia
Portal Hypertension
Acute Hemodynamic Response to Carvedilol in Children With Clinically Significant Portal Hypertension.
Clinically significant portal hypertension (CSPH) is defined as Hepatic Venous Pressure gradient (HVPG) >10 mmHg. Patients with CSPH are at risk of developing esophageal varices and clinical decompensation (variceal bleeding…
- Trial name
- NCT05767229
- Testing
- Carvedilol
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Anesthesia
Feasibility Study of a Hemodynamic Parameter Algorithm
An algorithm to calculate hemodynamic parameters based on blood pressure waveform was developed by collecting arterial blood pressure of patients during surgery
- Trial name
- NCT04520919
- Testing
- anesthesia;Radial artery puncture
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Hemodynamics
Perioperative Cerebrovascular Autoregulation Monitoring in Neurosurgical Patients
One of the challenges in pediatric anesthesiology is to ensure adequate cerebral perfusion pressure to prevent cerebral ischemia or hyperemia from pressure-passive perfusion.
- Trial name
- NCT04174001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
Pulmonary Hypertension
Evaluation of Feasibility of Ultrasonography Guided Pulmonary Artery Catheterization in Pulmonary Hypertension Diagnosis
Pulmonary artery catheters (PACs) that called Swan-Ganz catheters provide valuable information in select patient's especially pulmonary hypertension patiens.
- Trial name
- NCT07154927
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Mostafa K. Ahmed
Laryngeal Masks
Laryngeal Mask Insertion Conditions And Hemodynamic Effects
This interventional double-blind, randomized trial has included120 children of American Society of Anesthesiologist (ASA) physical status I or II aged between 1and 8 years of either sex, scheduled for outpatient minor surgery…
- Trial name
- NCT03257800
- Testing
- Ketamine
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- Leila mansali stambouli
Pre-Term
Placental Transfusion Effect on Hemodynamics of Premature Newborns
The objective of this study is to perform ultrasound Doppler measurements to evaluate the hemodynamic changes associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking…
- Trial name
- NCT04811872
- Testing
- Intact umbilical cord milking (I-UCM), Cut-umbilical cord milking(C-UCM), Delayed Cord Clamping (DCC)
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Marwa Mohamed Farag
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc