Clinical trials: Gastroenterology
Chronic Diarrhea
Epidemiology of Chronic Diarrhea Among Children Admitted to Gastroenterology Unit at Assuit University Children Hospital
Chronic diarrhea is defined as stool volume of more than 10g/kg/day in toddlers/infants and greater than 200 g/day in older children that lasts for 14 days or more.
- Trial name
- NCT03261297
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Abdominal Pain, Chronic Diarrhea
Evaluation of Fecal Calprotectin Screening and a Gastroenterology Questionnaire for Triaging Children With Chronic Abdominal Pain and/or Diarrhea Referred to a Pediatric Gastroenterology Service
Triaging new pediatric gastroenterology consultations is challenging as both inflammatory and non-inflammatory gastrointestinal (GI) diseases can present with non-specific chronic abdominal pain and/or diarrhea.
- Trial name
- NCT01866774
- Testing
- Fecal calprotectin level
- Where
- 2 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Queen's University
Gastroenterology Surgery, Tube Feeding
Efficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing
This is a single-center prospective study evaluating the efficacy of a prototype gastrostomy anchor dressing for use with button gastrostomy tubes.
- Trial name
- Tube Anchor (NCT07115134)
- Testing
- Bearables Gastrostomy Tube Dressing
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Children's National Research Institute
Gastroenterology & Work Related Injuries
Gastroenterology & Work Related Injuries
2.2.1. Primary Outcome(s) Percentage of gastroenterology fellows who have received any formal training in the ergonomics of endoscopy and how to prevent long term work related injuries. 2.2.2.
- Trial name
- NCT04216212
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Methodist Health System
Pancreatitis, Acute, Pain, Acute
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
The aim of the study is to assess the effectiveness and tolerance of pain treatment in AP in children using intravenous paracetamol in combination with ibuprofen or paracetamol in combination with metamizole.
- Conditions
- Pancreatitis, Acute, Pain, Acute, Pancreatic Disease, Pancreatic Diseases
- Trial name
- NCT07024199
- Testing
- The initial pain assessment, Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol), The effectiveness of the treatment
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- Medical University of Warsaw
Attitude, Staff, Behavior
The Attitudes and Behaviors of Gastroenterology Specialists on Anesthesia Procedures in Endoscopy Units
Most gastrointestinal endoscopic procedures are now performed with sedation and analgesia. Sedation and analgesia affects the quality of the procedure, patient co-operation and compliance as well as endoscopist's satisfaction.
- Conditions
- Attitude, Staff, Behavior, Anesthesia
- Trial name
- NCT03540238
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Crohn
Study of Photographs of Interest in Training to Obtain Good Reproducibility of the Diagnosis of Perianal Lesions of Crohn's Disease Inspection in Internal Gastroenterology
The diagnosis of LAP (lesions Ano-perineal) requires the inspection, palpation, anoscopy and possibly additional examinations including endoscopy and imaging; any of these steps of the diagnosis can only be replaced by another.
- Trial name
- PhotoCrohn (NCT02842450)
- Testing
- Photos + definitions, definitions only
- Where
- France
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph
Refractory Gastroesophageal Reflux Disease
Anti-reflux Mucosectomy (ARMS) is a Useful Therapy for Refractory Gastroesophageal Reflux Disease (RGERD)
Anti-reflux mucosectomy (ARMS) may be a new therapy for refractory gastroesophageal reflux disease (RGERD). The aim of the present study is to explore the safety and efficacy of ARMS.
- Trial name
- NCT03259191
- Testing
- anti-reflux mucosectomy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ruihua Shi
Diarrhea
Clinical Trial in Children Between 3 Months and 14 Years Old to Evaluate the Efficacy and Safety of Gelatin Tannate in the Treatment of Acute Diarrhea (INDIGO)
To evaluate the safety, global efficacy and rapidity of action of GT in children with acute gastroenteritis taking ORS solution.
- Trial name
- INDIGO (NCT04065529)
- Testing
- Gelatin tannate (GT) + oral rehydration solution (ORS) + Zinc supplementation
- Where
- Senegal
- Volunteers
- 150 people
- Sponsor
- Ferrer Internacional S.A.
Inflammatory Bowel Disease, Ulcerative Colitis
Pediatric FEcal Microbiota Transplant for Ulcerative Colitis
The PediFETCh study is a pilot trial designed to assess the feasibility of fecal microbiota transplants for the therapy of pediatric ulcerative colitis (UC) and pediatric inflammatory bowel disease-unclassified (IBD-U).
- Trial name
- PediFETCh (NCT02487238)
- Testing
- Fecal Microbiota Enema, Normal Saline Enema
- Where
- 3 sites in Canada
- Volunteers
- 35 people
- Sponsor
- McMaster Children's Hospital
HELICOBACTER PYLORI INFECTIONS
Feasibility Study to Diagnose Helicobacter Pylori in the Paediatric Population Using Non-invasive Fecal Analysis
Helicobacter pylori infection is a widespread bacterial disease affecting nearly half of the world's population. In children, the infection displays distinct features versus adults, with lower prevalence, variable symptoms, and…
- Trial name
- HEPYCA (NCT07083804)
- Testing
- Gastric biopsies, Stool sampling
- Where
- France
- Volunteers
- 188 people
- Sponsor
- Poitiers University Hospital
Colorectal Cancer
Efficacy of a Mobile Clinical Decision Support System (CaPtyVa CCR App) to Improve Performance of Gastroenterology and Coloproctology Specialists in Colorectal Cancer Screening and Surveillance According to Guideline Recommendations: A Randomized Clinical Trial.
This prospective study evaluates the use of a (Mobile Decision Support Systems), MDSS (CaPtyVa CCR app) in order to improves gastroenterology and coloproctology specialist's performance in CRC screening and surveillance according…
- Trial name
- NCT04389502
- Testing
- CaPtyVa app, Control group
- Where
- Argentina
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Aleman
Metabolic Liver Disorders in Children
The Prevalence of Metabolic Liver Disorders in Children
Aim of study : To detect the prevalence of metabolic liver disease in patients attending gastroenterology and hepatology unit at assuit university children hospital.
- Trial name
- NCT06197867
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pediatric Crohns Disease
Modified vs Standard CDED: Evaluation of a Nordic Adaptation of Nutritional Therapy in Paediatric Crohn's Disease
The primary aim of this clinical trial is to evaluate the clinical effectiveness of the Nordic Crohn's Disease Exclusion Diet (Nordic CDED) in children with Crohn's disease, measured by remission rates, and to compare these…
- Trial name
- N-CDED (NCT07334340)
- Testing
- Nordic Crohn´s Disease Exclusion Diet
- Where
- 3 sites in Sweden
- Volunteers
- 30 people
- Sponsor
- Vastra Gotaland Region
Eosinophilic Disorder, Eosinophilic Esophagitis (EoE)
New Cases of EoE in Children in Poland.
The aim of the study is to assess the incidence of EZP in Poland in the pediatric population and characteristics of Polish patients with EZP, i.e. their demographic, clinical, endoscopic and histological features.
- Conditions
- Eosinophilic Disorder, Eosinophilic Esophagitis (EoE), Eosinophilic Disease, Pediatric
- Trial name
- NCT07772388
- Testing
- Data collection
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Medical University of Warsaw
Pediatric Outpatients Encountered in Three Specialty Clinics, i.e. Respirology, Gastroenterology, and Genito-urology
Effects of Expert Arbitration on Clinical Outcomes When Disputes Over Diagnosis Arise Between Physicians and Their Artificial Intelligence Counterparts: a Randomized, Multicenter Trial in Pediatric Outpatients
We have recently developed an artificial intelligence (AI) framework to diagnose common pediatric diseases. This randomized controlled clinical trial aims to investigate the effects of expert arbitration on clinical outcomes in…
- Trial name
- NCT04011761
- Testing
- expert arbitration over discordant diagnoses made by AI diagnostic system and human doctors, respectively
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Guangzhou Women and Children's Medical Center
AI-assisted Colonoscopy
AI_Colonoscopy_for_Fellows
The goal of this study is to look at how good artificial intelligence (AI) assisted colonoscopy is compared to conventional colonoscopy in detecting polyps when used by gastroenterology fellows.
- Trial name
- NCT07661914
- Testing
- AI assisted colonoscopy, Conventional Colonoscopy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Functional Gastrointestinal Disorders, Functional Abdominal Pain Syndrome
Targeted Food Elimination for Treatment of Functional Gastrointestinal Diseases in Children
Recurrent Abdominal Pain (RAP) in children is common and causes significant functional impairment and poor quality of life. Lifestyle factors such as diet, anxiety, and stress are important triggers of abdominal pains, but there…
- Conditions
- Functional Gastrointestinal Disorders, Functional Abdominal Pain Syndrome, Abdominal Pain (AP)
- Trial name
- FGID (NCT02565355)
- Testing
- Dietary Exclusion, Standard Treatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Disordered Eating
Investigating Prevalence of Disordered Eating in Children With GI Disorders
Gastroenterological disorders are disorders affecting the stomach, intestines and associated organs. Symptoms of these types of disorders vary but often include vomiting, diarrhoea, weight loss and loss of appetite.
- Trial name
- NCT01872169
- Testing
- Disordered eating screening questionnaire
- Where
- United Kingdom
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Infantile Colic
Lactobacillus Reuteri Supplementation in the Treatment of Infantile Colic
The purpose of this study is to evaluate the efficacy of the oral administration of Lactobacillus reuteri in treating infantile colic as defined by the Rome III criteria.
- Trial name
- PROBIOC (NCT01887444)
- Testing
- Lactobacillus reuteri DSM17938 probiotic
- Where
- France
- Sponsor
- BioGaia AB