Clinical trials: Frail Elderly
Hematologic Disease, Neoplams
Retrospective Non-interventional Analysis of Opportunistic Infections in Immunocompromised and Frail Patients
The analysis of a cohort of consecutive non-selected patients from the Strasbourg University Hospital, and therefore representative of the real life, will allow better identifying the risk factors for these infections (by…
- Conditions
- Hematologic Disease, Neoplams, Transplantation, Immunologic Deficiency Syndromes
- Trial name
- NCT03920735
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Strasbourg, France
Adhd, ALS
National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.
The objective of the study will be to understand whether a supplementation of the diet with an active symbiotic, i.e. characterized by a mix of probiotics and a specially selected fiber with prebiotic activity combined with a…
- Conditions
- Adhd, ALS, Bronchial Asthma
- Trial name
- sPATIALS3 (NCT06005506)
- Testing
- Prebiotic fiber, Dietary fiber, Probiotic
- Where
- 4 sites in Italy
- Volunteers
- 64 people
- Sponsor
- Institute of Biomedical Technologies-National Research Council, Italy
Chronic Respiratory Failure
Telemedicine for Patients With Chronic Respiratory Insufficiency
In unstable patients needing oxygen and/or home mechanical ventilation, a nurse-centred TM programme (supported by continuous availability of a call centre and a pulsed oxygen system) is cost/effective saving health care…
- Trial name
- NCT00563745
- Testing
- telemedicine program
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Michele Vitacca
CLL (Chronic Lymphocytic Leukemia)
A Trial to Evaluate the Efficacy and Safety of a Fitness-adapted Thera-py Approach With Either Continuous Zanubrutinib Monotherapy or Time-limited Zanubrutinib + Sonrotoclax in Older and/or Frail Patients With Treatment-naïve CLL
The CLL-Frail2 trial will be a prospective, open-label, multicentre phase-II-trial to evaluate the efficacy and safety of a fitness-adapted therapy approach with either con-tinuous zanubrutinib (BGB-3111) monotherapy or…
- Trial name
- NCT07899398
- Testing
- Zanubrutinib, Sonrotoclax
- Volunteers
- 80 people
- Sponsor
- German CLL Study Group
Ageing
Implementation of Knowledge-Based Palliative Care
The research on ageing during the last couple of decades has increasingly focused on questions regarding the quality of life and life satisfaction of the old people.
- Trial name
- KUPA (NCT02708498)
- Testing
- Educational Intervention
- Where
- 30 sites in Sweden
- Volunteers
- 1,151 people
- Sponsor
- Lund University
Mildly Frail, Fragile and More Vulnerable
Using a Technology Assisted Physical Activity Program to Improve Muscle Strength, Joint Mobility, Standing Time,Self-efficacy and Life Satisfaction of Residents in Institutions
This study aims to examine the effectiveness of a technology-assisted physical activity program on improving muscle strength, joint mobility, standing time, self-efficacy, and life satisfaction among residents in institutions.
- Trial name
- NCT07199400
- Testing
- physical activity program
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan Normal University
Biliary Tract Infection
Ultrasound-guided Biliary Drainage Improving Prognosis in the Frail and High Risk Elderly Patients
Acute biliary tract infection is a kind of disease caused by bacteria of biliary tract infection, mainly including acute cholecystitis and acute cholangitis, especially acute obstructive suppurative cholangitis (AOSC),which can…
- Trial name
- NCT06960486
- Testing
- Bedside ultrasound-guided real-time biliary drainage, traditional appointment ultrasound
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hebei Medical University
Breast Cancer
Views and Attitudes of Oncologists and Geriatricians on the Use of Chemotherapy and Hormone Therapy in Treating Older and/or Frail Women With Breast Cancer
RATIONALE: A patient's age, health, and ability to perform daily activities may affect which treatment options are offered by doctors to older and/or frail women with breast cancer.
- Trial name
- NCT00478283
- Testing
- survey administration
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Neoplasms
Using Multimodal Prehabilitation to Improve Outcomes for Frail Patients Undergoing Resection of Colorectal Cancer
The purpose of this study is to determine if a program of physical activity, nutritional supplements and relaxation techniques is effective at decreasing post operative complications in frail colorectal cancer patients undergoing…
- Trial name
- NCT02502760
- Testing
- Physical Exercise Program, Whey Protein Isolate Powder, Relaxation Techniques
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Frailty, Caregiver Burnout
Mindfulness-Based Intervention for Caregivers of Frail Older Chinese Adults
This is study to investigate the effects of a brief mindfulness-based program for frail older adults caregivers.
- Trial name
- NCT04861610
- Testing
- Brief mindfulness based program, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Accidental Falls
Trial to Reduce Falls Incidence Rate in Frail Elderly
Background: Approximately 750,000 elderly Dutch people fall at least once a year, which often results in physical injuries and a fear of falling, with high costs and far-reaching consequences on functionality, physical activity…
- Trial name
- CP (NCT00512655)
- Testing
- Fall prevention course
- Where
- 3 sites in Netherlands
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Plasma Cell Myeloma
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
This phase III trial compares three-drug induction regimens followed by double-or single-drug maintenance therapy for the treatment of newly diagnosed multiple myeloma in patients who are not receiving a stem cell transplant and…
- Trial name
- NCT05561387
- Testing
- Bortezomib, Daratumumab and Hyaluronidase-fihj, Dexamethasone
- Where
- 397 sites in United States
- Volunteers
- 510 people
- Sponsor
- SWOG Cancer Research Network
Frail Elderly, Frailty
Frailty Training for Emergency Nurses: A Cluster RCT in Morocco
This study tests whether a training program helps nurses better recognize and care for older adults with frailty in hospital emergency departments.
- Trial name
- NCT07892612
- Testing
- Structured Educational Program on Geriatric Frailty
- Where
- Morocco
- Volunteers
- 144 people
- Sponsor
- Cadi Ayyad University
Coronary Artery Bypass Graft, Non-cardiac Thoracic Surgery
Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery
Frail Veterans are at increased risk for poor surgical outcomes, and as the Veteran population grows older and more frail, there is a critical need to identify effective strategies for reducing surgical risks for these patients.
- Conditions
- Coronary Artery Bypass Graft, Non-cardiac Thoracic Surgery, Frailty
- Trial name
- NCT03299101
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
Congestive Heart Failure, Heart Failure, Diastolic
Kyoto Congestive Heart Failure Study
The purpose of this study is to investigate the patient characteristics, selection of treatment, and factors associated with clinical outcomes in Japanese patients with acutely decompensated congestive heart failure.
- Conditions
- Congestive Heart Failure, Heart Failure, Diastolic, Heart Failure, Systolic, Elderly Frail
- Trial name
- KCHF (NCT02334891)
- Testing
- Standard
- Where
- Japan
- Volunteers
- 4,056 people
- Sponsor
- Kyoto University, Graduate School of Medicine
DLBCL
A Real-world Data and Sample Compendium of Frail and/or Multiply Treated Large B-cell Lymphoma
LBCL is a cancer of the lymphatic system where B-cells (a type of white blood cell) experience uncontrolled growth. The standard treatment for LBCL is a combination of chemotherapy and immunotherapy, referred to as…
- Trial name
- ALMANAC (NCT07335120)
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- The Clatterbridge Cancer Centre NHS Foundation Trust
Elderly, Frail
Improving Balance in Frail Elderly
The objective of this pilot study is to estimate, for a frail elderly population, the extent to which balance improves following a Core-Strength training program in comparison to a Stretch \& Strength program.
- Trial name
- NCT00785746
- Testing
- Core
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University
Residents in Longterm Care Facilities
Better tArgetting, Better Outcomes for Frail ELderly Patients
The acronym for this proposal, BABEL, refers to the fact that a common "language" - the interRAI risk-stratification and decision-making tool - will be used in this project, allowing several measures of care quality in long-term…
- Trial name
- BABEL (NCT06034444)
- Testing
- interRAI LTCF
- Where
- Canada
- Volunteers
- 5,692 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Frail Elderly
Factors Predisposing to Inappropriate Transfers of Nursing Home Residents to Emergency Departments
According to the data of our nursing homes (NH) research network (REHPA - Gérontopôle Toulouse, 345 nursing home in France), 13.5% of NH residents are hospitalized every 3 months or about 50% per year.
- Trial name
- FINE (NCT02677272)
- Testing
- Appropriateness of NH resident's transfer to ED
- Where
- 16 sites in France
- Volunteers
- 1,040 people
- Sponsor
- University Hospital, Toulouse
Frail Elderly, Elderly
Geriatric Education and Its Effect on Certain Aspects of Hospital Care of the Nursing Home Patients - 12 Month Retrospective Study
Nursing home patients admitted to the hospital poses significant challenge for health care providers. Geriatric teaching pays particular attention to these admissions and related problems.
- Conditions
- Frail Elderly, Elderly, Hospitalization, Geriatrics
- Trial name
- NCT01213225
- Volunteers
- 20 people
- Sponsor
- Maimonides Medical Center