Clinical trials: Fatty Pancreas
Cystic Fibrosis
Choline Nutrition in Children With Cystic Fibrosis
Cystic fibrosis (CF) is the most common lethal, inherited disorder among Caucasians. Choline is an essential vitamin and as a methyl donor is critically needed to support the normal metabolism.
- Trial name
- NCT01070446
- Testing
- Vitamin: Choline Bitartrate (2-hydroxyethyl) trimethylammonium salt 1:1
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis
The purpose of this study is to investigate the utility of a continuous glucose monitor device (CGM) in screening for cystic fibrosis related diabetes.
- Conditions
- Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis Liver Disease, Pancreatic Steatosis
- Trial name
- CFCGM (NCT03961516)
- Testing
- Frequently Sampled Oral Glucose Tolerance Test and CGM, MRI Pancreas and Liver
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University Hospitals Cleveland Medical Center
Cystic Fibrosis in Children
Effect of Antioxidant Docosahexaenoic Acid (DHA) in Cystic Fibrosis Patients
This study evaluates the effect of antioxidant docosahexaenoic acid (DHA) in patients with cystic fibrosis. Half of participants will receive DHA, while the other half will receive placebo.
- Trial name
- NCT04987567
- Testing
- ANTIOXIDANT DHA TRIGLYCERIDE (TRIDOCOSAHEXAENOINE-AOX®)
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Corporacion Parc Tauli
Cystic Fibrosis
Lipid Formulation to Increase the Bioavailability of Fatty Acids in Cystic Fibrosis (CF) Patients
The purpose of this trial is to evaluate if the use of a newly developed lipid formulation versus fish oil would better enable the absorption of essential fatty acids after 12 weeks of supplementation.
- Trial name
- NCT02646995
- Testing
- modified lipid formulation, Fish oil
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Société des Produits Nestlé (SPN)
Cystic Fibrosis, Pancreatic Insufficiency
Study of LYM-X-SORB™ to Improve Fatty Acid and Choline Status in Children With CF and PI
The purpose of this phase II research study is to evaluate the effectiveness of the next generation LYM-X-SORB™ in improving the essential fatty acid (EFA) and choline status for children and adolescents with Cystic Fibrosis (CF)…
- Trial name
- NCT00406536
- Testing
- Lym-X-Sorb powder
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Avanti Polar Lipids, Inc.
Gastric Tumor, Pancreatic Tumor
Parenteral Fish Oil in Major Laparoscopic Abdominal Surgery
The aim of this study is to assess the effect of postoperative parenteral fish oil on clinical outcome and immune function after major laparoscopic abdominal surgery.
- Conditions
- Gastric Tumor, Pancreatic Tumor, Liver Tumor
- Trial name
- NCT01819961
- Testing
- MCT/LCT and fish oil, MCT/LCT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wei Zhou
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cystic Fibrosis
Oral Docosahexanoic Acid Supplementation in Cystic Fibrosis
Oral supplementation of patients affected by cystic fibrosis with docosahexanoic acid (DHA) will result in normalization of the known fatty acid derangements in these patients and will diminish the production of proinflammatory…
- Trial name
- NCT00924547
- Testing
- Docosahexanoic Acid Supplement
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vanderbilt University
Cystic Fibrosis
Effect of Azithromycin on Fatty Acids in CF
In collaboration with Dr.Birgit Alteheld, Institute of Nutrional Sciences of the university of Bonn, Germany the following effect is explored: Effect of a 4 week therapy with AZT on synthesis of lipoproteins as well as…
- Trial name
- NCT03045198
- Testing
- Azithromycin
- Volunteers
- 20 people
- Sponsor
- University Childrens' Hospital (Zentrum für Kinderheilkunde des Universitätsklinikum Bonn)
Nonalcoholic Fatty Liver Disease After Pancreaticoduodenectomy
The Impact of Hepatic Steatosis on Survival After Pancreaticoduodenectomy
We will use simple summaries, educational handouts, and discussions with doctors and nurses to explain this study. The study looks at patients with early-stage pancreatic cancer who undergo pancreaticoduodenectomy (Whipple…
- Trial name
- NCT07182136
- Testing
- Pancreaticoduodenectomy
- Volunteers
- 200 people
- Sponsor
- Wei-Hsun Lu
Cystic Fibrosis
Use of Formula Fortified With DHA in Infants With Cystic Fibrosis
The hypothesis of this study is that feeding infants diagnosed with CF via newborn screening a formula enhanced with a specific fish-oil fatty acid known as DHA will improve growth and decrease pancreatic dysfunction (as measured…
- Trial name
- DHA (NCT00530244)
- Testing
- Docosahexaenoic acid (DHA), Standard formula (Enfamil)
- Where
- 24 sites in United States
- Volunteers
- 76 people
- Sponsor
- University of Massachusetts, Worcester
Acute Pancreatitis, Nonalcoholic Fatty Liver Disease
Association Between Nonalcoholic Fatty Liver Disease and Acute Pancreatitis
The early evaluation of AP severity are vital. Previous studies have shown non-alcoholic fatty liver disease (NAFLD) is associated with severity of acute pancreatitis (AP).
- Trial name
- NCT03566173
- Where
- China
- Volunteers
- 1,662 people
- Sponsor
- Ningbo No. 1 Hospital
Cystic Fibrosis
Omega 3 Supplementation in Cystic Fibrosis Patients
Essential fatty acids (EFA) deficiency has been often reported in patients with cystic fibrosis (CF), particularly in those homozygous for the DF508 mutation.
- Trial name
- NCT00959010
- Testing
- omega-3 triglycerides
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Queen Fabiola Children's University Hospital
Obesity & Overweight, Type 2 Diabetes Mellitus (T2DM)
MRI Assessment of Pancreatic Fat Changes and Islet Function Recovery After Bariatric Surgery in Obese Patients
This study evaluates changes in pancreatic fat and recovery of pancreatic function in obese patients undergoing laparoscopic sleeve gastrectomy (LSG), a weight-loss surgery.
- Conditions
- Obesity & Overweight, Type 2 Diabetes Mellitus (T2DM), Pancreatic Steatosis, Insulin Resistance
- Trial name
- PANFAT-BS (NCT07464223)
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- yu li，MD
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute