Clinical trials: Exotropia
Intermittent Exotropia
Improving Control of Alignment in Intermittent Exotropia
Aim 1: To determine whether use of dichoptic movies for 4 weeks may be helpful in improving control of alignment in children with intermittent exotropia (IXT), thus allowing IXT to be managed non-surgically Aim 2: To determine…
- Trial name
- NCT04199871
- Testing
- dichoptic 3D movies
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Retina Foundation of the Southwest
Dynamic Stereopsis in Intermittent Exotropia Patients
A Novel Dynamic Random-dot Stereopsis Assessment to Measure the Stereopsis in Intermittent Exotropia
A novel dynamic random-dot stereopsis test that included motion + disparity (MD), motion (M), and disparity (D), in which the disparity cues range from 200 to 1200 arc-seconds was used.
- Trial name
- NCT04152122
- Testing
- The dynamic stereopsis test
- Where
- China
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Moderate Intermittent Exotropia
Study of Surgical Treatment Versus Observation in Children With Moderate Intermittent Exotropia
The purpose of this study is to determine the long-term effect and security of the surgical treatment and observation only on ocular alignment, binocular stereopsis, and quality of life in children with moderate intermittent…
- Trial name
- SOMIX (NCT02736526)
- Testing
- recession or resection of the horizontal extraocular muscles
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sun Yat-sen University
Convergence Insufficiency Intermittent Exotropia (CI-IXT)
S-BLR Versus C-BLR for CI-IXT in Children
This is a multi-center, randomized single-blind controlled trial to compare the effectiveness of S-BLR with C-BLR for the treatment of CI-IXT in children.
- Trial name
- SCCIXT (NCT04064112)
- Testing
- S-BLR, C-BLR
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chen Zhao
Exotropia
Intermittent Exotropia in Egyptian Population
Strabismus is one of the most frequent ocular problems among developmentally normal children. The prevalence of strabismus varies among different regions, ranging from 0.06% in Japan to 5.65% in China.
- Trial name
- NCT06312865
- Testing
- Ophthalmic exam
- Volunteers
- 600 people
- Sponsor
- Assiut University
Intermittent Exotropia
Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent Exotropia
To determine the effectiveness of alternate occlusion therapy for the treatment of IXT among patients aged 3 to < 11 years old.
- Trial name
- CIAO (NCT02466659)
- Testing
- CIAO therapy Amblyz glasses
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Intermittent Exotropia
Visual Perceptual Learning Based Digital Therapeutics for Stereopsis in Intermittent Exotropia
This study evaluates the efficacy and safety of visual perceptual learning for improving stereopsis in intermittent exotropia. Half of participants will receive visual perceptual training using the Nu.T.
- Trial name
- NCT06117813
- Testing
- Nu.T, No-Treatment Control
- Where
- 6 sites in South Korea
- Volunteers
- 54 people
- Sponsor
- Nunaps Inc
Surgical Correction, V Pattern
Surgical Correction of V Pattern Intermittent Exotropia Without Inferior Oblique Muscle Overaction
Evaluation of the results of surgical correction of V pattern intermittent exotropia without inferior oblique muscle overaction by either performing bilateral lateral rectus recession (BLR) alone or performing bilateral lateral…
- Conditions
- Surgical Correction, V Pattern, Intermittent Exotropia, Inferior Oblique Muscle
- Trial name
- NCT07180199
- Testing
- Bilateral Lateral Rectus Recession (BLR Recession), Bilateral Lateral Rectus Recession with Upward Transposition
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Intermittent Exotropia, Myopia
A Comparative Study of the Efficacy of Myopia Control Lenses With Different Mechanisms on Controlling Myopia Progression in Patients With Intermittent Exotropia
The goal of this clinical trial is to compare the efficacy of myopia control lenses with different working principles in patients with intermittent exotropia aged 6 to 12 years.
- Trial name
- NCT07642934
- Testing
- DIMS glasses, DOT glasses
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Exotropia
Observation Versus Occlusion Therapy for Intermittent Exotropia
The present study is being conducted to assess the natural history of intermittent exotropia and to establish the effectiveness of occlusion in its treatment.
- Trial name
- IXT2 (NCT01032330)
- Testing
- occlusion treatment
- Where
- 2 sites in United States
- Volunteers
- 611 people
- Sponsor
- Jaeb Center for Health Research
Strabismus, Divergent
Lateral Rectus Muscle Strangulation in Cases of Exotropia
The goal of our study to evaluate effect of lateral rectus muscle strangulation as a novel effective weakening technique in cases of exotropia.
- Trial name
- NCT07373197
- Testing
- Muscle strangulation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Sohag University
Intermittent Exotropia
Bilateral Lateral Rectus Recession Versus Bilateral Primary Medial Rectus Resection in Intermittent Exotropia
The goal of this clinical trial is to compare the efficacy of bilateral lateral rectus recession and bilateral primary medial rectus resection in basic type intermittent exotropia Participants will be randomized into two groups…
- Trial name
- NCT06650735
- Testing
- BMR resection, BLR recession
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Strabismus, Esotropia
Risk Factors And Surgical Outcomes Of Strabismus Reoperation
Horizontal strabismus, commonly known as inward or outward deviation of the eyes, is a frequent eye condition that may require surgical correction.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- RSOR (NCT07446621)
- Testing
- Horizontal Strabismus Reoperation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Strabismic Deviation, Strabismus
Botulinum Toxin for Strabismus Treatment
The bacterial species Clostridium botulinum produces a class of neurotoxins known as botulinum toxin. At the neuromuscular junction, botulinum toxin A prevents acetylcholine from being released.
- Trial name
- Botox Squint (NCT07180394)
- Testing
- Botox injection into extraocular muscles
- Where
- Pakistan
- Volunteers
- 127 people
- Sponsor
- Foundation University Islamabad
Primary Exotropia, Strabismus
Accommodative Changes After Medial Rectus Resection Versus Plication in Primary Exotropia
Exotropia is a type of eye misalignment in which one eye turns outward. In some patients, surgery is needed to improve eye alignment and binocular function.
- Conditions
- Primary Exotropia, Strabismus, Strabismus Surgery, Exotropia
- Trial name
- NCT07637253
- Testing
- Lateral Rectus Recession combined with Medial Rectus Resection, Lateral Rectus Recession combined with Medial Rectus Plication
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Alternating Exotropia
Bil. LR Rec. Using Standard Tables VS Reduced Numbers in Intermittent Exo. in Children Under 6
comparing the motor alignment and the incidence of postoperative esotropia following the correction of intermittent exotropia in children below 7 years by bilateral lateral rectus recession using the standard recession tables…
- Trial name
- NCT04308538
- Testing
- Standard Recession, Reduced Recession
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Intermittent Exotropia
Office Based Vergence and Accommodative Therapy and Intermittent Exotropia
This pilot study is designed specifically to determine the short-term effect of OBVAT on intermittent exotropia in terms of 4 key areas (Standardizing reported outcomes of surgery for intermittent exotropia): control score…
- Trial name
- NCT03321838
- Testing
- accommodative/vergence therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sun Yat-sen University
Intermittent Exotropia
Office Based Vergence/Accommodative Therapy for the Treatment of Intermittent Exotropia
Effectiveness of office based vergence/accommodative therapy for the treatment of intermittent exotropia is investigated through a randomized clinical trial
- Trial name
- NCT04744779
- Testing
- Office-based accommodative/vergence therapy and home reinforcement
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Strabismus
Basic Intermittent Exotropia and Risk Factors for Postoperative Overcorrection and Under Correction
To evaluate preoperative risk factors for overcorrection and undercorrection following surgery for basic intermittent exotropia such as axial length of the globe, refractive error, age and sex
- Trial name
- NCT03153423
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Minia University