Clinical trials: Exercise Tolerance
Obesity
Influence of Cardio-ventilatory Factors on Exercise Intolerance in Obese Adolescents: Effects of Exercise Training
Worldwide, childhood and adolescent obesity has reached epidemic proportions despite major efforts to promote weight reduction. Pediatric obesity commonly presages adult obesity and is associated with the development of…
- Trial name
- VENTILOBE (NCT01411605)
- Testing
- Exercise training
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy, Children
Comparison Between 6 Minute Walk Test, 6 Minute Step Test and 4 Metre Gait Speed
The purpose of this study is to find an alternative to the six minute walk test by validating six minute step test and four metre gait speed in healthy children.
- Trial name
- NCT02318238
- Testing
- 6 minutes walking test, 6 minutes step test, 4 meters gait speed
- Where
- Belgium
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Liver Fat, Type 2 Diabetes
EXIT: Prospective Study of the Response to Exercise
Background : Regular exercise is a cornerstone in the prevention and the management of comorbidities. Unfortunately, the metabolic benefit of exercise training is not universal and varies among individuals.
- Trial name
- EXIT (NCT02204670)
- Testing
- Acute release of irisin after a single exercise session.
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Risk Assessment, Parenting
Randomized Controlled Trial of a Risk Reframing Tool to Change Mothers' Parenting Associated With Children's Risky Play
Children's risky play is associated with a variety of positive developmental, physical and mental health outcomes, including greater physical activity, self-confidence and risk management skills.
- Trial name
- NCT03374683
- Testing
- RR Digital Tool, RR In-Person Workshop, Position Statement on Active Outdoor Play
- Where
- Canada
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cystic Fibrosis
A Study of the Effects of Lumacaftor/Ivacaftor (LUM/IVA) on Exercise Tolerance in Subjects With Cystic Fibrosis (CF), Homozygous for the F508del-CFTR Mutation
This is a Phase 4, randomized, double-blind, placebo-controlled, parallel-group study in subjects aged 12 years and older with CF who are homozygous for the F508del-CFTR mutation.
- Trial name
- NCT02875366
- Testing
- LUM/IVA
- Where
- 12 sites in Australia, United Kingdom
- Volunteers
- 70 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Cystic Fibrosis (CF), Primary Ciliary Dyskinesia (PCD)
Upper Extremity Exercise Capacity, Muscle Oxygenation, and Balance in Pediatric CF and PCD
The number of studies evaluating respiratory functions and upper extremity functional exercise capacity in patients with CF and PCD is limited in the literature.
- Trial name
- NCT07148362
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Gazi University
Hematopoietic Stem Cell Transplantation
Effectiveness Rehabilitation Hematopoietic Transplantation (ovERsHOT)
The objective of the study is to evaluate the benefits and costs of a comprehensive rehabilitation program (physical, psychological, social and educational) for patients receiving hematopoietic stem cell transplantation (HSCT).
- Trial name
- ovERsHOT (NCT03324620)
- Testing
- Specific program functional and respiratory rehabilitation
- Where
- Spain
- Volunteers
- 190 people
- Sponsor
- Hospital Clinic of Barcelona
Anaemia, Asthma Exacerbations
Study on Effect of Papworth Technique in Anemic Asthmatic Pediatrics
As asthma is chronic condition which interferes with quality of life and exercise tolerance, so it is important to find out cost-effective alternative for the management of asthma due to increased prevalence and rising health…
- Trial name
- NCT06750354
- Testing
- papworth technique, aerobic training
- Volunteers
- 40 people
- Sponsor
- Cairo University
Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1
Evaluation of Exercise Testing and Physical Activity in Children and Adolescents Living With Inherited Arrhythmias
The goal of this observational study is to evaluate exercise testing and daily physical activity in children and adolescents who are diagnosed with an inherited arrhythmia.
- Conditions
- Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1, Catecholaminergic Polymorphic Ventricular Tachycardia Type 2
- Trial name
- ACTIVELY (NCT06661278)
- Testing
- Exercise tolerance test, Physical activity & heart rate monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Obesity, Insulin Resistance
Diabetes Prevention Program for Obese Latino Youth
The purpose of this study is to examine the effects of 12 week lifestyle intervention on diabetes risk in obese Latino adolescents.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- ELSC (NCT02039141)
- Testing
- Every Little Step Counts Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pulmonary Disease, Chronic Obstructive
Breathing Helium-Hyperoxia During Exercise in Patients With Chronic Obstructive Pulmonary Disease
Regular exercise can help patients with the lung disease, chronic obstructive pulmonary disease (COPD). But COPD patients have a hard time with training because of their breathing.
- Trial name
- NCT01283685
- Testing
- breathing helium-hyperoxia, breathing supplemental oxygen
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- West Park Healthcare Centre
Heart Failure, Ventricular Dysfunction, Left
Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use
The purpose of this study is to determine whether neuromuscular electrical stimulation can improve exercise tolerance for patients with heart failure and continuous dobutamine use in a hospital.
- Trial name
- NCT02668419
- Testing
- Neuromuscular Electrical Stimulator, Physical Therapy Session
- Where
- Brazil
- Volunteers
- 49 people
- Sponsor
- Federal University of São Paulo
Lung Transplantation
Effect of Early Pulmonary Rehabilitation After Lung Transplantation
The purpose of this observation study is to evaluate the effects of an early, 3 week lasting rehabilitation program, that starts roundabout 4 weeks after lung or combined lung transplantation, on physical activity, functional and…
- Trial name
- NCT00759538
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Hannover Medical School
Fabry Disease
Pulmonary Disease and Exercise Tolerance in Boys With Fabry Disease
When to start children with Fabry disease on therapy is controversial because of its expense and inconvenience. Many Fabry children complain of exercise intolerance.
- Trial name
- NCT01304875
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Cystic Fibrosis
Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough,in Cystic Fibrosis Patients
This randomized clinical trial aims to evaluate the effects of high-frequency chest wall oscillation (HFCWO) combined with concurrent training on cough, sputum clearance, exercise tolerance, and respiratory muscle strength in…
- Trial name
- NCT07519460
- Testing
- High-Frequency Chest Wall Oscillation, Concurrent Training
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease, COPD
The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD
The purpose of this study is to examine whether breathing helium-hyperoxia during exercise in a pulmonary rehabilitation program can improve the exercise tolerance and health related quality of life of patients with Chronic…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Lung Diseases
- Trial name
- NCT00406705
- Testing
- Helium-Hyperoxia
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Hypoxemia
The Effects of Wearing a Face Mask During Exercise in Youth Hockey Players During COVID-19
There is concern that wearing a face mask during COVID will affect oxygen uptake, especially during intense exercise. COVID transmission is especially prevalent in sports such as hockey, where there is close contact between…
- Trial name
- NCT04874766
- Testing
- Wingate exercise test and on-ice testing while wearing a face mask
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Univentricular Heart, Children, Adult
Respiratory Drive in Patients With Univentricular Congenital Heart Disease
The aim is to evaluate the correlation between the respiratory control to hypercapnia at rest and the VE/VCO2 slope measured during cardiopulmonary exercise testing.
- Trial name
- NCT03818373
- Testing
- polysomnography
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Cystic Fibrosis
LBM & Lung Function in Adolescents With CF
In patients with cystic fibrosis (CF) the commonest cause of death is respiratory failure. Respiratory failure can have many causes.
- Trial name
- NCT02797912
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- King's College Hospital NHS Trust