Clinical trials: Effectiveness
Comparative Effectiveness
Equivalence of Oral Melatonin and Oral Midazolam in Preoperative Anxiolysis for Pediatric Fast-Track Cardiac Surgery
Equivalence of Oral Melatonin and Oral Midazolam in Preoperative Anxiolysis for Pediatric Fast-Track Cardiac Surgery
- Trial name
- NCT07900321
- Testing
- Melatonin, Midazolam
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Effectiveness of Anesthesia Using Electronic Syringe in Children in the Context of Endotopy Treatment
Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe
This randomized clinical study aims to evaluate the efficacy and pain response of two local anesthesia techniques in pediatric dental treatment using an electronic syringe: ligament anesthesia and inferior alveolar nerve block…
- Trial name
- NCT07095946
- Testing
- Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Vaccine Effectiveness, HPV Vaccination
A Trial to Establish Non-inferiority of Immunogenicity of a Single-dose of CERVAVAC® Quadrivalent HPV Vaccine Compared to the Gardasil® Quadrivalent Vaccine Among Girls and Boys Aged 9 to 14 Years and in Girls/Women Aged 15 to 20 Years in Zambia
The goal of this study is to compare the immune response of the single dose of the CERVAVAC vaccine with the single dose of Gardasil vaccine in girls/women aged 9 to 20 and boys aged 9 to 14 at 6 months, 12 months and 24 months…
- Conditions
- Vaccine Effectiveness, HPV Vaccination, Single Dose, Immunogenicity
- Trial name
- CervALONE (NCT07256912)
- Testing
- quadrivalent HPV vaccine
- Where
- Zambia
- Volunteers
- 1,266 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Health Care, Pediatrics
Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)
Aim 1: Compare the effectiveness of focused dose vs extended dose hospital-to-home Transitional Care Interventions (H2H-TCI) on health service use and parent-reported confidence for hospitalized CYSHCN.
- Conditions
- Health Care, Pediatrics, Transitional Care, Comparative Effectiveness
- Trial name
- H2H-CYSHCN (NCT06428175)
- Testing
- Focused Dose Hospital-to-Home Transitional Care Interventions, Extended Dose Hospital-to-Home Transitional Care Interventions
- Where
- 2 sites in United States
- Volunteers
- 480 people
- Sponsor
- Duke University
Sexual Health, Mobile Application
Girls on Sexual Communication
Adolescents' sexual health has been an important issue for health care professionals, education and society. The purpose of this study was to examine the impact of a mobile application on adolescent girls' sexual communication…
- Conditions
- Sexual Health, Mobile Application, Female Adolescents, Dyadic Sexual Communication
- Trial name
- Girls (NCT07800728)
- Testing
- Girls
- Where
- Taiwan
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Insomnia, ADHD
Efficacy of Cognitive Behavioural Therapy for Insomnia and Bright Light Therapy in Adolescents With ADHD, Insomnia, and Evening Chronotype
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by persistent inattention, hyperactivity, and impulsivity.
- Conditions
- Insomnia, ADHD, Eveningness, Chronotype
- Trial name
- NCT07767617
- Testing
- CBT-I with Bright Light Group
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Tuberculosis (TB), Tuberculosis in Children
Shorter Treatment Regimen Implementation Evaluation Study
"Evaluation of the implementation of the shorter treatment regimen for children and adolescents with non-severe TB in Zambia" is a parallel and convergent mixed methods evaluation study of implementation and clinical outcomes of…
- Conditions
- Tuberculosis (TB), Tuberculosis in Children, Tuberculosis Treatment Effectiveness, Tuberculosis Active
- Trial name
- EvSTR (NCT07747792)
- Where
- Zambia
- Volunteers
- 175 people
- Sponsor
- Centre for Infectious Disease Research in Zambia
Training Effectiveness, Training Efficiency
Impact of Respiratory Training on Reaction Time and Other Performance Components in Young Football Players.
The overall aim of the study is to gain knowledge about the impact of respiratory training on reaction time and other components of performance in young football players.
- Conditions
- Training Effectiveness, Training Efficiency, Football Players
- Trial name
- NCT07737379
- Testing
- Respiratory training
- Where
- 2 sites in Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Assessment of Physical Examination Skills for the Cardiovascular System, Determining Levels of Academic Self-Efficacy
Examining the Effects of ARCS-Based Education on Cardiovascular System Physical Examination Skills, Motivation, and Self-Efficacy Levels in Nursing Students
Objective: The purpose of this study is to determine the effect of ARCS-based nursing education on skill levels, motivation, and self-efficacy in the physical examination of the cardiovascular system.
- Conditions
- Assessment of Physical Examination Skills for the Cardiovascular System, Determining Levels of Academic Self-Efficacy, Determining Motivation Levels, Evaluation of the Effectiveness of the ARCS Intervention
- Trial name
- NCT07733479
- Testing
- ARCS Model Education, Structured Supplementary Training Based on the ARCS Motivation Model
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Sexually Transmitted Infection, HIV/AIDS
Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)
This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes.
- Conditions
- Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness, Birth Outcomes
- Trial name
- NCT04446611
- Testing
- First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure)
- Where
- South Africa
- Volunteers
- 2,247 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Effectiveness of Chlorohexidine, Effectiveness of Essential Oil
Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients
The goal of this clinical trial is to evaluate and compare the antiplaque efficacy and patient reported outcome of three commonly used antiseptic mouthwashes - Chlorhexidine (CHX), Cetylpyridinium Chloride (CPC), and Essential…
- Conditions
- Effectiveness of Chlorohexidine, Effectiveness of Essential Oil, Effectiveness of Cetylpyridinium Chloride
- Trial name
- NCT07490873
- Testing
- Chlorohexidine 0.12% mouthwash, Cetylpyridinium chloride 0.05% mouthwash, Essential Oil mouthwash
- Where
- Iraq
- Volunteers
- 20 people
- Sponsor
- University of Baghdad
Team-effectiveness Research, School-based Interventions
Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD
The proposed project aims to integrate team-based implementation strategies with an established school-based intervention for children with ADHD, the Collaborative Life Skills Program (CLS), to enhance its implementation and…
- Conditions
- Team-effectiveness Research, School-based Interventions, Attention Deficit/ Hyperactivity Disorder, Implementation Science
- Trial name
- NCT06180681
- Testing
- Team-Enhanced Collaborative Life Skills Program, Standard Collaborative Life Skills Program
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Anesthesia Effectiveness
Pain Perception During Inferior Alveolar Nerve Block Administration in Children Using Vibraject and Dental Vibe Versus Conventional Syringe
This RCT study aims to establish evidence based decision comparing between Vibraject (MiltexInc LLC.,York,PA,USA).and Dental vibe(BING Innovations LLC,Crystal Lake,IL,USA versus Conventional Syringe on pain perception during…
- Trial name
- NCT07571278
- Testing
- Vibraject, Dental vibe, Conventional syringe
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children
Plaque Removal in Children Using Charcoal and Nylon Toothbrushes
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush.
- Trial name
- NCT07563400
- Testing
- soft charcoal infused bristle toothbrush (iLive) with bamboo handle, soft nylon bristle toothbrush (Oral B JUNIOR 6-12)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Effectiveness of the I-arch System
Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment
The goal of this clinical trial is to learn if the I-arch system works to align the moderately misaligned teeth in patients seeking orthodontic treatment.
- Trial name
- NCT07264127
- Testing
- The use of 0.016×0.014 copper nickel titanium arch wire during the alignment stage., Use of 0.014- then 0.016-inch heat-activated nickel titanium arch wire during the alignment stage.
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- Tabark H. Omran
Effectiveness of Application Education Intervention, Noise Induced Hearing Loss
Prevention of Noise-Induced Hearing Loss in Primary Education
The goal of this randomized controlled trial is to evaluate the effectiveness of the educational program the HoorToren in promoting recreational safe listening behavior among Dutch primary school children in group 7 (aged 10-11…
- Conditions
- Effectiveness of Application Education Intervention, Noise Induced Hearing Loss, Behavior Change Interventions, Primary School Children
- Trial name
- NCT07513077
- Testing
- HoorToren educational package
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Myopia, Cost-effectiveness Analysis
Comparing Myopia Treatments in Youth: Defocus Spectacles, Glasses, and Ortho-K
The research project titled "A Comparative Study on the Clinical Efficacy, Quality of Life, and Cost of Use of Peripheral Defocus Spectacles, Frame Glasses, and Orthokeratology Lenses in Myopic Children and Adolescents" aims to…
- Conditions
- Myopia, Cost-effectiveness Analysis, Quality of Life
- Trial name
- NCT06278974
- Where
- China
- Volunteers
- 90 people
- Sponsor
- He Eye Hospital
Intubation, Intratracheal, Airway Management
Pediatric Airway: Noninferiority Trial of Devices for Intubation Assessment
The goal of this clinical trial is to find out whether the BESDATA BD-DF videolaryngoscope works as well as the McGRATH™ MAC videolaryngoscope for placing a breathing tube in infants during surgery.
- Conditions
- Intubation, Intratracheal, Airway Management, Video Laryngoscope, Cost Effectiveness
- Trial name
- PANDA (NCT07351227)
- Testing
- Intubation
- Where
- Brazil
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Effectiveness
A Study on the Efficacy and Safety of Telitacicept in the Treatment of Children Ocular Myasthenia Gravis
Under conventional treatment regimens, pediatric ocular myasthenia gravis (OMG) is prone to relapse and is associated with corticosteroid-related adverse effects, indicating an unmet clinical need.
- Trial name
- NCT07298928
- Testing
- Telitacicept
- Where
- 3 sites in China
- Volunteers
- 30 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
This Study Aims to Evaluate the Effectiveness of the INJEX Device in Administering Local Anesthesia
Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia.
Local anesthesia is a common and essential procedure for the majority of dental treatments. The most frequently used method of administration is needle injection.
- Trial name
- NCT07426523
- Testing
- INJEX 30, Traditional syringe
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University