Clinical trials: Diabetic Neuropathy Peripheral
Diabetic Foot Ulcer (DFU), Neuropathy (Disorder)
Effect of Foot-ankle Exercise Using Elastic Band
The goal of this clinical trial is to learn if foot-ankle exercise can prevent diabetic foot ulcer incidence in patient with diabetes neuropathy.
- Trial name
- NCT07229794
- Testing
- foot-ankle exercise
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- St Elisabeth School Health Science
Diabetic Neuropathies, Peripheral Nerve Diseases
Effect of Exercise on Gait and Balance in Peripheral Neuropathy
The purpose of this study is to find out if participation in one of the study groups: functional balance training, Tai Chi, or education, results in better outcomes overall.
- Conditions
- Diabetic Neuropathies, Peripheral Nerve Diseases, Peripheral Nervous System Diseases
- Trial name
- NCT00270842
- Testing
- Tai Chi, Functional Balance, Education Control group
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- US Department of Veterans Affairs
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Diabetes Type 1, Proteomics
Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD)
The aim of the present study is to investigate a targeted proteomic analysis in plasma of children - of Greek origin- with type 1 diabetes (DT1) and its correlation with the electrophysiological findings that accompany diabetic…
- Conditions
- Diabetes Type 1, Proteomics, Diabetic Peripheral Neuropathy
- Trial name
- PAPD (NCT04257877)
- Testing
- Blood sampling
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Diabetic Neuropathies, Herpes Zoster
Dextromethorphan Versus Placebo for Neuropathic Pain
In our current clinical trial, we are comparing the effects of two NMDA receptor antagonists to placebo in patients with painful distal symmetrical diabetic neuropathy or post-herpetic neuralgia.
- Conditions
- Diabetic Neuropathies, Herpes Zoster, Neuralgia
- Trial name
- NCT00001344
- Testing
- dextromethorphan
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Diabetic Polyneuropathy, Diabetes Mellitus, Type 2
Alpha Lipoic Acid and Diabetes Mellitus: Potential Effects on Peripheral Neuropathy
Patients with type 2 DM who are following will be enrolled into the study. Two visits were scheduled for data collection, physical examination and laboratory testing of the patients: the first prior to initiation of alpha lipoic…
- Trial name
- NCT04322240
- Testing
- Alpha lipoic acid
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Diabetic Polyneuropathy
A Double-Blind, Placebo-Controlled Study of Fermented Deglycyrrhizinated Licorice Extract
This double-blind, placebo-controlled study evaluated the efficacy of oral α-amylase enzyme replacement therapy in treating early-stage diabetic polyneuropathy (DPN).
- Trial name
- NCT07148804
- Testing
- Fermented Deglycyrrhizinated Licorice, Non-fermented Deglycyrrhizinated Licorice
- Where
- Egypt
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Helwan University
Diabetes Mellitus, Diabetic Neuropathies
Integrated Oral Care Intervention for Xerostomia in Diabetes Patients
Diabetes patients commonly experience dry mouth also known as xerostomia which can affect eating speaking oral health and overall quality of life.
- Trial name
- IOCID (NCT07425275)
- Testing
- Integrated Oral Care Intervention
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Khyber Medical University Peshawar
Diabetic Autonomic Neuropathy
Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus
Patients with diabetes mellitus and definite autonomic and peripheral neuropathy were randomized to receive quinapril or no treatment for 2 years.
- Trial name
- NCT03031834
- Testing
- Quinapril
- Sponsor
- Aristotle University Of Thessaloniki
Diabetes Mellitus, Polyneuropathies
Cost-effectiveness of In-shoe Pressure Measurement for Therapeutic Shoes
The purpose of this study is determine whether the use of plantar pressure measurements in the production of customized therapeutic footwear for patients with diabetes and a history of foot ulceration results in lower production…
- Trial name
- NCT02061059
- Testing
- block 1, block 2, standard
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University
Type 1 Diabetes Mellitus
Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes
The proposed project is a clinical intervention trial testing the feasibility and effectiveness of diabetic retinopathy screening evaluated by artificial intelligence (AI) based software in children with type 1 diabetes (CwD).
- Trial name
- PAIRS-T1D (NCT07149142)
- Testing
- Non-mydriatic fundus camera photography, Fundus ophtalmoscopy, Optic coherence tomography
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- University Hospital, Motol
Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy
Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective Study
Diabetes mellitus type I is an increasing burden for more and younger children. Therapy should avoid long-term complications as macrovascular diseases and diabetic nephropathy, retinopathy and diabetic neuropathy (DN).
- Conditions
- Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy, Nerve Conduction Study Not Performed
- Trial name
- NCT01512030
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Landeskrankenhaus Feldkirch
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Diabetic Neuropathy
Alpha Lipoic Acid for Treatment of Diabetic Neuropathy
Patients with diabetic neuropathy and total symptoms score(TSS) >7 points were invited to this open multicenter study. Patients were free of pain medications and severe diabetic complications .Patients started alpha lipoic acid…
- Trial name
- NCT02439879
- Testing
- Alpha lipoic acid
- Volunteers
- 45 people
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
Diabetic Neuropathy Peripheral
Evaluating a Nitric Oxide Generator, Nebivolol as a Disease Modifier in Patients With Diabetic Neuropathy.
The goal of this clinical trial is to test in patients with diabetic neuropathy, Can Nevibolol at a dose of 2.5 mg- 10 mg compared with standard pain modulating treatment conserve the mean nerve action potential amplitude (sural…
- Trial name
- EVANESCENT-DPN (NCT06201611)
- Testing
- Nebivolol+ Standard care arm, Epalrestat + Alpha Lipoic Acid +Standard care, Standard care alone
- Where
- 2 sites in India
- Volunteers
- 120 people
- Sponsor
- St. John's Research Institute
Diabetic Autonomic Neuropathy, Diabetic Neuropathy
High Diagnostic Performance of the Indicator Plaster Neuropad for the Detection of Diabetic Autonomic Neuropathy
Diabetic autonomic neuropathy (DAN) is a prevalent and severe complication of Diabetes Mellitus (DM). When the autonomic regulation of the cardiovascular system is affected, it is referred to as cardiovascular autonomic…
- Trial name
- NCT06734143
- Testing
- Neuropad
- Where
- Greece
- Volunteers
- 174 people
- Sponsor
- Aristotle University Of Thessaloniki
Diabetic Neuropathies
Botulinum Toxin Type A in Diabetic Peripheral Neuropathy
Background: Diabetes mellitus is commonly complicated by diabetic peripheral neuropathy. Due to common side effects and poor tolerance to medication, poor adherence to medication is common in diabetic peripheral neuropathy.
- Trial name
- NCT05296759
- Testing
- botulinum toxin A, Gabapentin, Duloxetine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Neuropathy; Peripheral, Autonomic, in Diabetes Mellitus (Manifestation)
The Relationship Between Vascular Adhesion Protein-1 and Diabetic Cardiovascular Autonomic Neuropathy
Exploring the relationship between serum VAP-1 and cardiovascular autonomic neuropathy in subjects with type 2 diabetes mellitus
- Trial name
- NCT01706289
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Diabetes Complications
New Diagnostic Tool (MinION) for Identifying Microorganisms in Foot Wounds of Patients Living With Diabetic Foot Osteomyelitis
Diabetic foot wound infections are predominantly polymicrobial. However, 'conventional' microbiological culture does not identify all the bacteria potentially involved in these infections and requires time, which can have a…
- Conditions
- Diabetes Mellitus, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- MINI-OS (NCT07391995)
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetic Peripheral Neuropathy
Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx®
The purpose of this research study is to determine if Metanx improves sensory neuropathy in persons with Type 2 diabetes. Metanx is a medical food available with a prescription from a physician.
- Trial name
- NCT00933998
- Testing
- Metanx® (Oral L-methylfolate, Methylcobalamin and Pyridoxal 5'-phosphate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carolina Musculoskeletal Institute