Clinical trials: Diabetic Foot
Diabetic Foot, Diabetes Mellitus
The Role of Extrinsic Foot Muscles Chances in Determining the Risk of Diabetic Foot Ulcer
Many foot and lower limb disorders resulting from diabetes, such as deformity, muscle weakness, reduced range of motion, stiffness of connective tissue, amount of oxygenation, functional capacity, poor balance and coordination…
- Trial name
- NCT06736210
- Testing
- Muscle Elastic Properties Measurement, Muscle Oxygen Saturation (SmO2), Plantar Pressure Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
The aim of this study is to evaluate the chance of non-healing diabetic foot ulcers repair by improving the condition of lack of oxygen or hypoxia in the wound area caused by diabetes using methylene blue along with the use of…
- Trial name
- NCT05850611
- Testing
- Methylene Blue, Milk (control), Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Diabetic Foot Ulcer (DFU), Neuropathy (Disorder)
Effect of Foot-ankle Exercise Using Elastic Band
The goal of this clinical trial is to learn if foot-ankle exercise can prevent diabetic foot ulcer incidence in patient with diabetes neuropathy.
- Trial name
- NCT07229794
- Testing
- foot-ankle exercise
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- St Elisabeth School Health Science
Wound, Diabetes
Pathology of Skin, Nerve and Vasculature in the Amputated Limb of Diabetes
1. To explore the pathology of nerve, vascular, and skin in the amputated leg 2. To diagnose small-fiber sensory neuropathy of the contralateral leg by investigating the skin intervention 3.
- Conditions
- Wound, Diabetes, Amputation
- Trial name
- NCT00840164
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Diabetic Foot Ulcer
Pathogenicity Factors of Staphylococcus Pettenkoferi in Foot Wounds and Osteitis in Diabetic Patients
Gram-positive cocci, particularly Staphylococcus aureus and coagulase-negative staphylococci (SCoN), are the bacteria most frequently isolated from diabetic foot ulcers. Although studies have been carried out on the role of S.
- Trial name
- PETTENK-OS (NCT06688084)
- Testing
- Molecular epidemiology of the collection, Study of the resistome of the S. pettenkoferi population, Study of the virulome of the S. pettenkoferi population
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetic Foot Ulcer
Longitudinal Study of Chronic Wounds Using Novel Wound Measurement Technologies
An open, non-randomised longitudinal study of diabetic foot ulcers receiving standardised treatment, over a 16 week period conducted at out-patient level, utilising novel optical wound measurement technologies.
- Trial name
- NCT02967900
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Michelson Diagnostics Ltd.
Impaired Wound Healing, Diabetes Mellitus
Wound Healing In Diabetes (WHy) Study
This observational study aims to identify risk factors and molecular mechanisms of impaired wound healing, to guide better foot care in the diabetic population.
- Trial name
- WHy (NCT01002521)
- Where
- Barbados
- Volunteers
- 605 people
- Sponsor
- The University of The West Indies
Diabetic Foot
Cost-effectiveness Evaluation of Two 10% Urea Creams in Patients With Diabetic Foot Syndrome
Randomised, double-blind, cost-effectiveness clinical trial of two 10% urea creams purchased in pharmacies and supermarkets in patients with diabetic foot syndrome.
- Trial name
- NCT05588258
- Testing
- Participants were given the 10% urea cream purchased in pharmacy or supermarket as appropriate after randomisation and their foot skin quality was assessed by validated questionnaire.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Diabetic Foot Ulcer, Amputation
Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers
Chronic foot ulcers occurring among diabetic patients are difficult to heal. The frequent elderly age with co-morbidities, vascular insufficiencies, peripheral neuropathies and super imposed infections, all contribute towards the…
- Trial name
- NCT00393510
- Testing
- TCM
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Wounds, Pressure Ulcer
Kerecis Real-World Fish Skin Graft Registry
Multi-center, observational (i.e., non-interventional), open-label, real-world Registry on the Use of Kerecis Devices
- Conditions
- Wounds, Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
- Trial name
- ISACOD (NCT06384183)
- Testing
- Kerecis Fish Skin Graft
- Where
- 6 sites in United States
- Volunteers
- 600 people
- Sponsor
- Kerecis Ltd.
Diabetic Foot, Amputation
Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort Study
This study explored the pattern and type of amputations performed on patients with diabetic foot who were admitted to our institution, as well as the 7-year mortality rate of patients with diabetic foot at the same institution.
- Trial name
- NCT05123157
- Testing
- NO intervention
- Where
- Saudi Arabia
- Volunteers
- 358 people
- Sponsor
- King Abdulaziz University
Venous Leg Ulcer (VLU), Diabetic Foot Ulcer (DFU)
A Real World Data Collection of Human Amniotic Membrane(s) on Diabetic Foot Ulcers, Venous Leg Ulcers, Pressure Ulcers and Post Operative Wounds
This study is designed to evaluate the effectiveness of Tri-Membrane Wrap™, Membrane Wrap™ and Membrane Wrap-Hydro™ compared to the effectiveness of Standard of Care alone though a retrospective data collection.
- Conditions
- Venous Leg Ulcer (VLU), Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
- Trial name
- NCT07078968
- Testing
- Tri-Membrane Wrap™, Membrane Wrap™, Membrane Wrap-Hydro™
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- BioLab Holdings
Diabetic Foot, Diabetes Complications
Local Application of Autologous Bone Marrow Cells for Treatment of Chronic Diabetic Ulcers
Bone marrow cells were previously shown to enhance wound healing in experimental diabetes. In this pilot study, patients with chronic diabetic ulcers not healing under conventional therapy, will be treated with local application…
- Trial name
- NCT00292357
- Testing
- Application of autologous bone marrow
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heidelberg University
Toenail Fungal Infection, Cellulitis
A Subjective Observational Study of Patients Using Medicated Footbath/Footwash Treatment in Podiatry Care
The purpose of this study is to evaluate the level of relief perceived by patients using medicated footbath/footwash with or without an oral medication for the treatment of podiatry issues.
- Conditions
- Toenail Fungal Infection, Cellulitis, Pitted Keratolysis, Diabetic Foot Ulcer
- Trial name
- NCT03781024
- Testing
- Footwash
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Data Collection Analysis Business Management
Diabetes Mellitus, Polyneuropathies
Cost-effectiveness of In-shoe Pressure Measurement for Therapeutic Shoes
The purpose of this study is determine whether the use of plantar pressure measurements in the production of customized therapeutic footwear for patients with diabetes and a history of foot ulceration results in lower production…
- Trial name
- NCT02061059
- Testing
- block 1, block 2, standard
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University
Diabetic Foot Ulcer
Effectiveness and Safety of Early-Stage Amputation and External Herbs Chitosan for Diabetic Foot Ulcer
Diabetic Foot as the popular chronic complications of diabetes, is one of the main factors leading to limb amputation, it was reported that the amputation rate is 15 times of the non-diabetic patients.
- Trial name
- NCT02413086
- Testing
- Early-stage amputation, Amputation, External herbs chitosan
- Volunteers
- 320 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Diabetic Mellitus, Laser
Helium-Neon Laser Therapy Versus Infrared Laser Therapy in Treating Patients With Diabetic Foot Ulcer
Background: Diabetic patients are frequently showed with foot ulceration as a common complication which increases to 20% in admission.
- Trial name
- NCT03338517
- Testing
- Helium Neon Laser
- Volunteers
- 65 people
- Sponsor
- Ahlia University
Diabetes Mellitus
Assessing Diabetic Foot Ulcer Microcirculation With High-frequency Contrast Enhanced Ultrasound
The objective of this observational study is to investigate and validate the utility of high-frame-rate ultrasound imaging technology for dynamic observation of the blood perfusion process at the site of ulcer wounds in…
- Trial name
- NCT06309082
- Testing
- Amputation, Debridement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Diabetic Foot
Bacteriological Study of Diabetic Foot and Antibiotic Sensitivity Pattern in Eastern India
The pattern of organism causing diabetic foot infection are presumed to vary from location to location depending on the antibiotic prescription practice, geographical locations, environmental variations and therapeutic…
- Trial name
- NCT01351701
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Sun Valley Hospital, Guwahati