Clinical trials: Depression, Involutional
Involutional Depression, Anxiety Disorders
MRI Study of Brain Activity and Risk for Depression in Adolescents
Anxiety in children of parents with major depressive disorder (MDD) poses a particularly high risk for later-life MDD. In adults, MDD involves dysfunction in prefrontal brain regions that regulate attention to emotional stimuli.
- Trial name
- NCT00047944
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bone Diseases, Metabolic, Depression, Involutional
Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
In this study researchers would like to learn more about the low levels of bone mineral density seen in approximately half of women in their forties diagnosed as currently having or previously had depression.
- Conditions
- Bone Diseases, Metabolic, Depression, Involutional, Osteoporosis
- Trial name
- NCT00001916
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorder, Involutional Depression
Study of the Psychological Development of Children of Parents With and Without Affective Disorders
This research study is the continuation of a study started more than 20 years ago. The study was designed to explore the effect that depressed parents have on their children and to better understand the factors that contribute to…
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001170
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorder, Involutional Depression
Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial
This study will examine the effectiveness of omega-3 fatty acids, compounds found in plants and fish, in treating bipolar disorder. Some studies have indicated that omega-3 fatty acids may be effective in treating mood disorders.
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001146
- Testing
- Ethyl Eicosapentaenoic Acid, OmegaBrite
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy, Involutional Depression
Dynamics of Leptin and Endocrine Function
This is a study investigating the hormones and substances important to the stress response. The hormone that is most directly responsible for stress response is called corticotropin-releasing hormone (CRH).
- Trial name
- NCT00001543
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)