Clinical trials: Delirium Prevention
Emergence Agitation
Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
The goal of this clinical trial is to compare Efficacy of low dose propofol(0.5 mg/kg) vs placebo given at the end of sevoflurane anesthesia for prevention of emergence agitation in pediatric patient undergoing MRI scan.
- Trial name
- NCT06218680
- Testing
- Propofol, Normal saline
- Where
- Thailand
- Volunteers
- 134 people
- Sponsor
- Khon Kaen University
Emergence Delirium, Anesthesia
Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children
This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will…
- Trial name
- NCT07799311
- Testing
- propofol 1mg/kg, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Delirium, Psychomotor Agitation
Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement
Myringotomy tube placement is one of the most commonly performed operations in children. Emergence delirium after such procedures is common.
- Trial name
- NCT02383004
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Emergence Delirium
Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children
Study where children will receive one premedication, either intranasal dexmedetomidine or oral midazolam, to reduce agitation on emergence of anesthesia.
- Trial name
- NCT03171740
- Testing
- Dexmedetomidine, Midazolam oral solution, Oral saline
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Brasilia University Hospital
Remimazolam, Tonsillectomy
Remimazolam for Emergence Delirium Prevention in Children Undergoing Tonsillectomy
The aim of this study is to confirm the effectiveness of remimazolam in preventing delirium during emergence from anesthesia in children who will undergo elective procedures of tonsillectomy, adenotonsillectomy or adenoidectomy…
- Conditions
- Remimazolam, Tonsillectomy, Emergence Delirium
- Trial name
- NCT07704437
- Testing
- Remimazolam 20 MG Injection [Byfavo], NaCl (0,9%)
- Where
- Croatia
- Volunteers
- 110 people
- Sponsor
- University Hospital of Split
Emergence Delirium
Emergence Agitation of Sevoflurane in Pediatric
Low dose nalbuphine versus dexmedetomidine on prevention of emergence agitation in children
- Trial name
- NCT06830564
- Testing
- we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure, we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sevoflurane Anaesthesia
Effect of Animated Cartoon for Prevention of Emergence Agitation in Children Aged 1.5 - 5 yr After General Anesthesia
Emergence agitation (EA) in children early after sevoflurane anaesthesia is a common postoperative problem, with incidence ranging up to 80%.
- Trial name
- NCT01880138
- Testing
- watching animated cartoon before general anesthesia, not watching animated cartoon beofre general anaesthesia
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Agitation, Child
Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery
This study is a single-center, prospective, randomized, controlled trial. To investigate if preoperative using of eye patch will decrease emergence agitation, and to provide a better method of decreasing emergence agitation to…
- Conditions
- Agitation, Child, Anesthesia
- Trial name
- NCT02590744
- Testing
- eye patch, non-eye patch
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xiaoliang Gan
Tonsillectomy
Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation
To Determine The Efficacy of a Rapid Bolus Injection of Dexmedetomidine on the Incidence of Emergence Agitation in Anesthetized Children and the Cardiovascular Profile of a Rapid Bolus Injection of Dexmedetomidine.
- Trial name
- NCT01528891
- Testing
- Dexmedetomidine
- Where
- 2 sites in United States
- Volunteers
- 418 people
- Sponsor
- Peter Davis
Emergence Delirium
Ketofol Versus Dexmedetomidine for Prevention of Emergence Delirium in Pediatric Patients Undergoing Squint Surgeries
The aim of the study is to compare the effectiveness of ketofol for the prevention of emergence delirium in pediatric patients undergoing squint surgery, in comparison to dexmedetomidine.
- Trial name
- NCT06545890
- Testing
- Ketamine, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ambulatory Surgical Procedures
Effect of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery
Emergence agitation/delirium (EA/ED) is a common complication in pediatric surgery patients, which increases the risk of developing postoperative airway obstruction and respiratory depression.
- Trial name
- NCT03262090
- Testing
- 0.2ug/kg dexmedetomidine, 0.4ug/kg dexmedetomidine, 0.6ug/kg dexmedetomidine
- Where
- China
- Volunteers
- 389 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Strabismus
Comparison of Propofol 1mg/kg and Propofol 0.5mg/kg for Prevention of Emergence Agitation in Children Undergoing Strabismus Surgery During Sevoflurane Anesthesia
The occurrence of emergence agitation (EA) in pediatric patients who have received sevoflurane anesthesia is a common postoperative problem.
- Trial name
- NCT02152787
- Testing
- Injection of propofol 1.0mg/kg, propofol 0.5mg/kg, normal saline
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Pediatric ALL, Pediatric Anesthesia
Nalbuphine Versus Ketamine for Prevention of Emergence Agitation After Sevoflurane in Children Undergoing Tonsillectomy
The effect of low dose nalbuphine or ketamine in the prevention of emergence agitation after sevoflurane anesthesia in children undergoing tonsillectomy with or without adenoidectomy.
- Trial name
- NCT05176119
- Testing
- Nalbuphine Injection, Ketamine, Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Surgery, Delirium - Postoperative
VR-Based Cognitive Stimulation Games for Delirium Prevention
This trial aims to evaluate the feasibility, safety, and acceptability of a virtual reality (VR)-based cognitive stimulation game to reduce postoperative delirium among older surgical patients at high risk due to pre-existing…
- Conditions
- Surgery, Delirium - Postoperative, Delirium
- Trial name
- NCT07641153
- Testing
- Virtual Reality Software, Virtual Reality movies, Nurse led control arm
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- The Methodist Hospital Research Institute
Pediatric Delirium
Pediatric Delirium
Preventing emergent delirium in pediatric ambulatory surgery through preoperative use of intra-nasal Dexmedetomidine and oral Midazolam.
- Trial name
- NCT04669457
- Testing
- Intra-nasal Dexmedetomidine, Oral Midazolam
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Emergence Delirium
Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics
The aim of the present study is to compare the effect of IV infusion 0.5 µg/kg dexmedetomidine and IV 0.1 mg/kg nalbuphine in preschool children for prevention of emergence agitation after adenotonsillectomy under sevoflurane…
- Trial name
- NCT04058899
- Testing
- Dexmedetomidine, Nalbuphine, infusion pump
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Emergence Delirium
Intranasal Dexmedetomidine Versus Intranasal Midazolam for Emergence Delirium Prevention
This study is a double-blind clinical trial, in pediatric patients aged 1-12 years with physical status ASA (American Society of Anesthesiology) 1 and 2 who underwent eye surgery under general anesthesia using Sevoflurane…
- Trial name
- NCT04263844
- Testing
- Intranasal dexmedetomidine, Intranasal Midazolam
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Universitas Indonesia
Specified Sedative, Hypnotic
Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric
The purpose of this study is to investigate the effect of diphenhydramine on the prevention of sevoflurane induced emergence delirium/ agitation in pediatrics.
- Trial name
- NCT02463929
- Testing
- Diphenhydramine, normal saline, Ketamine
- Volunteers
- 50 people
- Sponsor
- Universitas Diponegoro
Emergence Delirium
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children
Postoperative agitation and emergence delirium describe a spectrum of symptoms of early postoperative negative behavior, in which the child experiences a variety of behavioral disturbances including crying, thrashing, and…
- Trial name
- MELA-PAED (NCT05541276)
- Testing
- Melatonin, Isotonic sodium chloride solution
- Where
- Denmark
- Volunteers
- 676 people
- Sponsor
- Arash Afshari
Emergence Agitation, Emergence Delirium
Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Emergence Agitation and Delirium in Children Undergoing Tonsillectomy and Adenoidectomy
Brief Summary This study is designed to find out whether transcutaneous auricular vagus nerve stimulation (taVNS) can safely reduce restlessness and confusion when children wake up from anesthesia after tonsillectomy and…
- Trial name
- NCT07394647
- Testing
- Active taVNS Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University