Clinical trials: Coenzyme Q10
Oral Aphthous Ulcer
Clinical Evaluation of Topical Coenzyme Q10 in Management of Oral Aphthous Ulcer
Recurrent oral aphthous ulcer is the most common oral lesion in occurrence and one of cause is oxidative stress so investigators need to use antioxidant drugs like topical coenzyme Q10 gel to treat the lesion and more safe for…
- Trial name
- NCT03213769
- Testing
- topical coenzyme Q10 gel, Carpabol gel
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Huntington's Disease
Coenzyme Q10 in Huntington's Disease (HD)
The goals of this trial are to determine if coenzyme Q10 is effective in slowing the worsening symptoms of Huntington's disease and to learn about the safety and acceptability of long-term coenzyme Q10 use by determining its…
- Trial name
- 2CARE (NCT00608881)
- Testing
- coenzyme Q10
- Where
- 49 sites in United States, Australia and 1 more
- Volunteers
- 609 people
- Sponsor
- Massachusetts General Hospital
Mitochondrial Diseases
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease
To show that oral CoQ10 is a safe and effective treatment for children with inborn errors of mitochondrial energy metabolism due to defects in specific respiratory chain (RC) complexes or mitochondrial DNA (mtDNA) mutations, and…
- Trial name
- NCT00432744
- Testing
- CoenzymeQ10
- Where
- 3 sites in United States, Canada
- Volunteers
- 24 people
- Sponsor
- University of Florida
Muscular Dystrophy, Duchenne
An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy
This study will help to determine the safety and efficacy of the nutritional supplement Coenzyme Q10 when added to steroids as a treatment for Duchenne muscular dystrophy (DMD).
- Trial name
- NCT00033189
- Testing
- Coenzyme Q10
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Myelodysplastic Syndrome
The Efficacy of Coenzyme Q10 And Curcumin in Patients With Myelodysplastic Syndromes
To determine the clinical effects of coenzyme Q10 and Curcumin in improving the cytopenias of patients with myelodysplastic syndromes.
- Trial name
- NCT00247026
- Testing
- curcumin; coenzyme q10
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Coenzyme Q10, Alveolar Cleft Grafting
Effect of Co-enzyme Q10 on the Bone Volume of Alveolar Cleft Reconstruction
Evaluate the effect of Co-enzyme Q10 on the bone volume in unilateral alveolar cleft repair
- Trial name
- NCT07045246
- Testing
- Coenzyme Q 10, iliac bone graft
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Oral Lichen Planus
Clinical and Biochemical Assessment of the Effect of Topical Use of Coenzyme Q10 Versus Topical Corticosteroid in Management of Symptomatic Oral Lichen Planus: Randomized Controlled Clinical Trial
The aim of the present investigation is to assess the clinical therapeutic effect of topical use of Coenzyme Q10 versus topical corticosteroid in management of symptomatic oral lichen planus and determine whether the effect, if…
- Trial name
- NCT04091698
- Testing
- Co-Enzyme Q10 mucoadhesive tablets
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Migraine
Influence of a Dietary Supplement as Treatment of Migraine in Children and Adolescents
Migraine in children and adolescents can be associated with low serum levels of coenzyme q10, the key-enzyme of mitochondrial energy production.During migraine attacks inflammation is an important issue.
- Trial name
- NCT01010711
- Testing
- Migra 3
- Where
- 2 sites in Germany
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Complen Health GmbH
Dilated Cardiomyopathy
Coenzyme Q10 Supplementation in Children With Idiopathic Dilated Cardiomyopathy
This study aims to determine the effect of Coenzyme Q10 supplementation on conventional therapy of children with heart failure due to idiopathic dilated cardiomyopathy.
- Trial name
- NCT02115581
- Testing
- Coenzyme Q10
- Where
- Iran
- Volunteers
- 38 people
- Sponsor
- University of Tehran
Polycystic Ovary Syndrome
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled…
- Trial name
- NCT01910766
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Cyclic Vomiting Syndrome
The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)
This is a study with the principle goal being to learn about the use of L-Carnitine and CoQ10, two vitamin supplements that are currently being used to treat Cyclic Vomiting Syndrome, largely initiated by parents.
- Trial name
- NCT00728104
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Autism Spectrum Disorder, Phelan-McDermid Syndrome
Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome.
This double-blind, cross-over, randomized, controlled trial (RCT) has the aim of evaluating the effectiveness of a metabolic support therapy in two cohorts of patients with idiopathic Autism Spectrum Disorder or Phelan-McDermid…
- Trial name
- Q10ASD (NCT04312152)
- Testing
- Q10 Ubiquinol, Vitamin E, Multi-Vitamin B complex
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Antonio Persico
Hemodialysis
Efficacy and Safety of Coenzyme Q10 in Pediatric Hemodialysis Patients
All chronic kidney disease patients, whether on regular hemodialysis or not, are at high risk of cardiovascular diseases. This is mainly due to increased oxidative stress, reduced antioxidants and generalized inflammation.
- Trial name
- NCT05170893
- Testing
- Coenzyme Q10
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Parkinson Disease
Effects of High-dose Coenzyme Q10 on Biomarkers of Oxidative Damage and Clinical Outcome in Parkinson Disease
The investigators hypothesise that measuring biomarkers of oxidative damage could better inform investigators on the potential merits (and pitfalls) of CoQ10 supplementation in PD subjects.
- Trial name
- NCT01892176
- Testing
- coenzyme q10
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
Preeclampsia
Coenzyme Q10 Supplementation and Development of Preeclampsia
As preeclampsia is a disease specially affecting young and primiparous women, and due to the fact that we found previously in several studies a prevalence of 12%, to ensure a confidence of 95% and a power of 80%, it is necessary…
- Trial name
- NCT00300937
- Testing
- Coenzyme Q10
- Where
- Ecuador
- Volunteers
- 235 people
- Sponsor
- Teran, Enrique, MD, PhD
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Duchenne Muscular Dystrophy
CoQ10 and Prednisone in Non-Ambulatory DMD
This study will help determine if CoQ10 and prednisone, alone and as a combination decrease the decline in cardiopulmonary and skeletal muscle function that occurs in the wheelchair confined phase of DMD.
- Trial name
- NCT00308113
- Testing
- Prednisone, Coenzyme Q10
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Systemic Lupus Erythematosus
The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus
The goal of this clinical trial is to evaluate the safety and efficacy of coenzyme Q10 supplementation in pediatric patients with SLE.
- Trial name
- NCT07096557
- Testing
- Coenzyme Q10
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
Clinical Trial of Coenzyme Q10 and Lisinopril in Muscular Dystrophies
The study will include 120 participants aged 8 and up with Duchenne, Becker, or autosomal recessive limb-girdle (specifically: LGMD 2C-2F and 2I) muscular dystrophies that have no clinical cardiac symptoms.
- Conditions
- Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Limb Girdle Muscular Dystrophy
- Trial name
- NCT01126697
- Testing
- Coenzyme Q10 and Lisinopril
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 63 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Cyclic Vomiting Syndrome
Analysis of Q10 Coenzyme Efficacy for Long-term Treatment of Cyclic Vomiting Syndrome in Children
The main purpose of this study is the comparison of frequency of vomiting episodes (number of episodes per year) observed during the year after the begin of Q10 coenzyme treatment to frequency observed during the year before the…
- Trial name
- COENZYME (NCT03295760)
- Testing
- Q10 Coenzyme
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Central Hospital, Nancy, France