Clinical trials: Chronic Musculoskeletal Pain
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Osteoarthritis
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint
This study will examine the effectiveness of injected hylan (Synvisc) for treating pain associated with osteoarthritis of the temporomandibular joint (jaw joint) and improving function of the joint.
- Trial name
- NCT00078351
- Testing
- High molecular weight hylan (Synvisc) injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Knee Pain Chronic, Osteo Arthritis Knee
Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.
This is an Individual Patient Expanded Access IND of autologous adipose derived Mesenchymal Stem Cells with the primary goal of treating 1 individual with bilateral knee pain who has exhausted all treatment options, his condition…
- Trial name
- NCT04604288
- Testing
- HB-adMSC
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Healthy, Shoulder Impingement Syndrome
Injury Prevention Programs in Overhead Athletes
To evaluate and describe the effect of performing an integrated injury prevention exercises on the variables considered as injury risk factors in overhead athletes
- Conditions
- Healthy, Shoulder Impingement Syndrome, Shoulder Injury, Shoulder Pain Chronic
- Trial name
- IPOverhead (NCT06747702)
- Testing
- Injury prevention workout
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Temporomandibular Disorders, Psychological Distress
How Dentists' Personality Traits Affect Communication and Treatment Outcomes in TMD Patients
This prospective, longitudinal study investigates the influence of dentists' personality traits on patient-reported outcomes among individuals with temporomandibular disorders (TMDs) undergoing splint therapy.
- Conditions
- Temporomandibular Disorders, Psychological Distress, Chronic Orofacial Pain
- Trial name
- TMD (NCT07074366)
- Testing
- Splint Therapy with Structured Communication
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Rotator Cuff Tendinosis
Effects of Rotator Cuff Drills Versus Progressive Resistance Exercises on Chronic Rotator Cuff Tendinopathy
A single-blinded randomized clinical trial was conducted with 30 male overhead athletes (17-35 years) recruited from cricket clubs and sports complexes in Faisalabad.
- Trial name
- NCT07726030
- Testing
- Rotator cuff Drills, Progressive resistance exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Chronic Pain, Chronic Pain Syndrome
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
The goal of this clinical trial is to learn if adding Shiatsu therapy to standard treatment can improve quality of life in children and adolescents with chronic pain that is not caused by inflammation.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain and Comorbid Emotional Problems, Chronic Pain, Psychogenic
- Trial name
- ShiQoL (NCT06929598)
- Testing
- Shiatsu Therapy
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Chronic Musculoskeletal Pain
Pain Relief Investigation of NeuroModulation Therapy in Adult Humans
The study is being performed to determine the efficacy and safety of Fralex Neuromodulation Therapy (F-NMT), delivered by the Fralex PRIMA device, in reducing chronic musculoskeletal pain.
- Trial name
- NCT00253032
- Testing
- PRIMA
- Sponsor
- Fralex Therapeutics
Chronic Pain, Osteoarthritis
Predicting Successful Outcome of Interdisciplinary Biopsychosocial Rehabilitation in Osteoarthritis
The goal of this prospective study is to identify variables that can predict whether an interdisciplinary biopsychosocial intervention for patients with osteoarthritis will be successful.
- Conditions
- Chronic Pain, Osteoarthritis, Disability Physical
- Trial name
- CIR-predict (NCT05661760)
- Testing
- interdisciplinary multimodal pain treatment
- Where
- Netherlands
- Volunteers
- 2,309 people
- Sponsor
- Maastricht University
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Cryoanalgesia, Pain Management
The Prevalence of Chronic Pain Following Cryoanalgesia and the Nuss Procedure.
The aim of the study is to analyze the prevalence of chronic pain, including neuropathic pain following operations for funnel chest deformity of the anterior chest wall in children.
- Conditions
- Cryoanalgesia, Pain Management, Chronic Pain, Funnel Chest
- Trial name
- NCT07923500
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Pomeranian Medical University Szczecin
Duchenne Muscular Dystrophy (DMD), Chronic Pain
Does Chronic Pain Change Over Time in Children With Duchenne Muscular Dystrophy?
1. Brief Summary This prospective observational study aims to evaluate the 6-month longitudinal changes in chronic pain, pain characteristics, coping strategies, and functional performance in children and adolescents aged 7 to 18…
- Conditions
- Duchenne Muscular Dystrophy (DMD), Chronic Pain, Neuromuscular Diseases (NMD)
- Trial name
- NCT07892196
- Testing
- Routine Clinical Follow-up and Pain Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Antalya Training and Research Hospital
Knee Osteoarthritis
Effectiveness of Blood Flow Restriction Exercise Therapy to Reduce Pain in Knee Osteoarthritis Patients
Resistance training of knee extensor muscles is being used in physiotherapy management in knee osteoarthritis (OA) to improve pain and physical function.
- Trial name
- BFR;OA (NCT04917952)
- Testing
- Blood Flow Restriction (BFR)
- Volunteers
- 42 people
- Sponsor
- University of West Attica
Chronic Pain, Exposure
Agile Development of a Digital Exposure Treatment for Youth With Chronic Musculoskeletal Pain
This project proposes to systematically develop and evaluate the feasibility and preliminary effectiveness of a digitally delivered, graded exposure treatment for youth with chronic musculoskeletal pain, utilizing a sequential…
- Conditions
- Chronic Pain, Exposure, Adolescent Behavior, Child Behavior
- Trial name
- NCT05079984
- Testing
- Graded exposure treatment (GET)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Stanford University
Thoracic Surgery, Scoliosis; Adolescence
Chronic Pain After Scoliosis and Thoracic Surgery in Children
The aim of this epidemiologic prospective study is to determine the prevalence of CPSP defined as pain occurring 4 months after scoliosis and thoracic surgery and rated > 3 on a 10 point visual analogue scale or FLACC scale, in…
- Conditions
- Thoracic Surgery, Scoliosis; Adolescence, Pediatric ALL, Chronic Pain
- Trial name
- PEDIACHROII (NCT02995525)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Bordeaux
Pain, Chronic, Pain Syndrome
Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain
The goal of this clinical trial is to learn about resilience coaching in adolescents with chronic musculoskeletal pain. The main questions it aims to answer are to 1) determine how helpful resilience coaching is for teens with…
- Conditions
- Pain, Chronic, Pain Syndrome, Psychological
- Trial name
- NCT05834725
- Testing
- Promoting Resilience in Stress Management, Usual Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital of Philadelphia
Chronic Pain, Juvenile Idiopathic Arthritis
Turkish Validity and Reliability of Pain Catastrophizing Scale-Child (PCS-C)
Perception of chronic pain and related disability; occurs through the interaction of physiological and psychological processes. Pain catastrophizing is a cognitive attribution style characterized by a negative mindset and…
- Trial name
- NCT05436301
- Testing
- Pain Catastrophizing Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Fibromyalgia, Chronic Widespread Pain
12-years Follow-up on 166 Female Patients With Fibromyalgia or Chronic Widespread Pain
A 12-year follow-up of 166 women with fibromyalgia (FM) or chronic widespread pain (CWP) in western Sweden. The 166 women participated in a Randomised Controlled Trial called GAU in 2004-2005, aiming to investigate the effect of…
- Trial name
- NCT02872129
- Where
- 3 sites in Sweden
- Volunteers
- 126 people
- Sponsor
- Göteborg University
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati