Clinical trials: Alveolar Bone Resorption
Angle Class I
Root Resorption and Alveolar Bone in the Maxillary Canine Retraction Using Injectable Platelet-rich Fibrin: A Split-Mouth Trial
Prolonged orthodontic treatment is a risk factor for root resorption, so accelerating the speed of tooth movement using different methods can limit tooth root resorption.
- Trial name
- NCT06634888
- Testing
- Injectable platelet rich fbirin
- Where
- Vietnam
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusion, Angle Class II, Division 1
Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399760
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Clift Lip, Cleft Palate
Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone)
Study Objective The objective of this study was to evaluate and compare postoperative pain and hospital costs in pediatric patients with cleft lip and palate undergoing alveolar bone grafting surgery.
- Conditions
- Clift Lip, Cleft Palate, Alveolar Bone Loss, Postoperative Pain
- Trial name
- NCT07734974
- Testing
- Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sirio-Libanes
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Periodontal Bone Loss, Periodontitis
The Role of Granulation Tissue in Periodontal Regeneration
The goal of this observational study is to distinguish the infectious, healing, and regeneration-related characteristics of two types of gingival granulation tissues, namely infra-osseous and supra-osseous granulation tissues, in…
- Conditions
- Periodontal Bone Loss, Periodontitis, Periodontal Disease, Periodontal Diseases
- Trial name
- NCT07254117
- Where
- Latvia
- Volunteers
- 34 people
- Sponsor
- Riga Stradins University
Alveolar Cleft
Partial Maxillary Expansion With Post Grafting Expansion vs. Pre Full Maxillary Expansion in Secondary Alveolar Cleft
Intermediate grafting with both pre- and post- grafting maxillary expansion with time span after grafting 6-8 weeks for consolidation and final retention for 3 months after finalization of expansion will get the advantages of…
- Trial name
- NCT05941988
- Testing
- pre grafting partial maxillary expansion with post grafting expansion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Cleft
Evaluation of Bilateral Alveolar Cleft Grafting With Micro Plate Stabilization Versus Conventional Grafting Technique
The aim of the study is to enhance the maxillary segments stability during graft healing using microplate fixation to be compared with conventional grafting technique regarding gained bone quality and quantity.
- Trial name
- NCT06523855
- Testing
- bilateral alveolar cleft grafting using iliac crest particulate and microplate fixation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Bone Loss
3D Printed Customized Bone Graft for Alveolar Regeneration: Longitudinal Cohort Evaluation
This study will evaluate the behavior of the implant-supported restorations (prosthesis) placed into the areas grafted with the 3D printed customized bone (personalized graft produced to fit a specific bone defect), as well as…
- Trial name
- NCT07405918
- Testing
- Clinical evaluation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Alveolar Bone Grafting
E-Polycaprolactone-Containing Membrane in Alveolar Bone Regeneration
This study aimed to evaluate the effectiveness of synthetic polycaprolactone (PCL) bioscaffold membranes used for alveolar augmentation in maxillofacial surgery for increasing the amount of newly formed bone after…
- Trial name
- NCT06627621
- Testing
- Alveolar Ridge Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- cem üngör
Alveolar Clefts, Alveolar Bone Grafting
Evaluation of Using Iliac Crest With and Without Platelet-Rich Fibrin in Repair of Congenital Alveolar Cleft
A randomized clinical trial aims to evaluate the clinical and radiographic outcomes of the repair of congenital alveolar clefts using Iliac crest graft with and without mixing with platelet-rich fibrin
- Conditions
- Alveolar Clefts, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- NCT06924216
- Testing
- alveolar bone grafting, alveolar bone grafting Plus Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Suez Canal University
Alveolar Bone Loss, Tooth Extraction Status Nos
Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone
This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in…
- Conditions
- Alveolar Bone Loss, Tooth Extraction Status Nos, Immediate Implant Placement
- Trial name
- NCT07449806
- Testing
- Immediate Implant Placement with Medpark S1 xenograft, Immediate Implant Placement with bio-Oss xenograft
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Basma Gamal Mohamed Ahmed
Alveolar Bone Resorption, Alveolar Bone Grafting
Split Crest Procedure: Is It Necessary to Fill the Gap?
This prospective controlled clinical study evaluates the effectiveness of adding bone graft or dentin graft material during the split crest (alveolar ridge splitting) procedure for horizontal ridge augmentation with simultaneous…
- Conditions
- Alveolar Bone Resorption, Alveolar Bone Grafting, Bone Expansion
- Trial name
- NCT07272694
- Testing
- Split Crest Technique
- Where
- Serbia
- Volunteers
- 24 people
- Sponsor
- Vladimir Biocanin
Alveolar Bone Loss, Periodontitis
Intraoral Ultrasound Imaging of Tooth-periodontium Complex
Misaligned teeth are very common in the population and are commonly known as malocclusion. This happens when the upper teeth do not align properly with the lower teeth.
- Trial name
- NCT04971642
- Testing
- Intraoral ultrasound
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Bone Resorption
Using Platelet Rich Plasma in Reducing Alveolar Bone Resorption During Rapid Maxillary Expansion
The purpose of this study is to determine if the injection of Platelet-rich plasma (PRP) is effective in reducing alveolar bone loss that happens after each rapid maxillary expansion (RME) on the buccal aspect of the posterior…
- Trial name
- NCT03028038
- Testing
- Platelet Rich Plasma, No Platelet Rich Plasma
- Where
- Syria
- Volunteers
- 16 people
- Sponsor
- Damascus University
Alveolar Bone Loss
Comparison of Coronally Advanced Lingual Flap to Modified MPI for Flap Advancement in Partially Edentulous Patients
Comparison of cronally advanced lingual flap to modified periosteal releasing incision (MPRI)
- Trial name
- NCT03466840
- Testing
- The coronally advanced lingual flap, Modified periosteal releasing Incision
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Bone Loss
Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth.
- Trial name
- NCT02972788
- Testing
- Enamel Matrix Proteins Derivative, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Bone Loss, Alveolar
L-PRF in Alveolar Ridge Preservation
The effect of leucocyte- and platelet-rich fibrin (L-PRF) for enhancing the healing after dental extractions is still a matter of debate.
- Trial name
- L-PRF (NCT03408418)
- Testing
- Platelet-rich fibrin
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Alveolar Bone Loss
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.
- Trial name
- NCT02709525
- Testing
- hyaluronic acid
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Periodontal Bone Loss
Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the treatment of periodontal intrabony…
- Trial name
- NCT03707483
- Testing
- combination of vitamin C and platelet rich fibrin
- Volunteers
- 20 people
- Sponsor
- Cairo University
Maxillofacial Bone Defect, Alveolar Bone Loss
Bone Marrow Mononuclear Cells for the Repair of Severe Maxillofacial Bone Defects
This is a single-center, single-arm, open-label clinical study conducted at the Department of Stomatology, Nanjing Drum Tower Hospital.
- Trial name
- NCT07852806
- Testing
- Autologous bone marrow-derived mononuclear cells (BMMNCs), Bio-Oss bone graft material with collagen membrane
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School