Clinical trials: Adverse Childhood Experience
Adverse Childhood Experience, Depression / Major Depressive Disorder
Preventive and Personalized Digital Emotion Regulation Skills Intervention to Reduce Depression and Anxiety in Youths With Adverse Childhood Experiences
The present study aims to determine whether a personalized digital psychoeducation intervention (active intervention group) is more effective than self-monitoring of one's mood (control group) in reducing emotion regulation…
- Conditions
- Adverse Childhood Experience, Depression / Major Depressive Disorder, Anxiety Depression, Anxiety
- Trial name
- PREVENT-DERS (NCT07921446)
- Testing
- Lifestyle psychoeducation intervention, Personalized digital psychoeducation intervention on emotion regulation
- Volunteers
- 140 people
- Sponsor
- Institute of Mental Health, Singapore
Substance-Related Disorders, Adverse Childhood Experiences
Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program
Primary Objective: Conduct a rigorous evaluation of a prevention-based intervention designed to mitigate the harms of adverse childhood experiences (ACEs) exposure and prevent future ACEs, substance use, and overdose within 36…
- Trial name
- NCT06236100
- Testing
- Strengthening Families Program + Family Advocate, Strengthening Families Program
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- RTI International
Adverse Childhood Experiences, Domestic Violence
The Impact of an Adapted Version of the Strengthening Families Program on IPV Among Caregivers and ACEs Among Children
Adverse childhood experiences (ACEs) are unfortunately common and the known outcomes are concerning. However, very little is currently known about programs that may prevent ACEs among children, such as witnessing intimate partner…
- Trial name
- NCT05129501
- Testing
- Experimental
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Adverse Childhood Experiences
Journey of Hope in Appalachia: Supporting Resilience in the Region's Youth
Rural youth have heightened exposure to adverse childhood experiences (ACES) such as poverty, social isolation, chronic hunger, and drug use in the home.
- Trial name
- JOHA (NCT04096937)
- Testing
- Focus groups
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gia Mudd
Mental Health Outcomes, Adverse Childhood Experiences
School Violence Exposure as an Adverse Childhood Experience
This study hypothesize that school safety strategies may contribute to poor mental health and distress among various school populations and proposes the following research questions to be answered through this study: 1.
- Conditions
- Mental Health Outcomes, Adverse Childhood Experiences, Perceived School Safety, Educational Outcomes
- Trial name
- NCT06153316
- Testing
- School shooting incident
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Depression in Adolescence, Adverse Childhood Experiences
Life Experiences in Adolescents and the Development of Skills
The primary objective of this study is to assess acquisition and retention of a Cognitive Behavioral Therapy (CBT)-based "cognitive restructuring" skill, among young adolescents (12-15 years of age) with elevated depression…
- Trial name
- LEADS (NCT04719897)
- Testing
- FIRST: Repairing Thoughts
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Pittsburgh
Stress-related Problem, Stress, Emotional
Effects of Parent-Adolescent Joint I-Interventions for Adolescents with Adverse Childhood Experiences
The study aims to examine the effectiveness of internet-based Parent-Adolescent Joint Interventions in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as…
- Trial name
- EASY-PEP-i (NCT06650696)
- Testing
- PCE promotion, Psychoeducation, Emotiaonl skill enhancement
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Anxiety, Stress Disorder, Posttraumatic
BLOOM: Boldly Living outdOOrs for Mental Health
In 2019, the Office of the California Surgeon General launched the ACEs Aware Initiative in collaboration with the California Department of Health Care Services.
- Conditions
- Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
- Trial name
- BLOOM (NCT05973123)
- Testing
- Group Nature Outings, Family Outings
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Emotion Regulation, Adverse Childhood Experience
Paired Emotion Reading Improves Emotion Regulation in Rural Children With ACE
The goal of this study is to explore the feasibility and effectiveness of the online Paired Emotion Reading Intervention (PERI) on the emotion regulation of rural children with adverse childhood experiences (ACE), as compared…
- Trial name
- NCT06505629
- Testing
- the online Paired Emotion Reading Intervention (PERI), the online Paired General Reading Intervention (PGRI)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University
Adverse Childhood Experiences
Implementation of Adverse Childhood Experiences (ACEs) Policy
Adverse Childhood Experiences (ACEs) are pervasive among children with 45% experiencing at least one ACE and 10% experiencing three or more, placing them at high risk for toxic stress and symptomatology.
- Trial name
- NCT04916587
- Testing
- Implementation Strategy of ACEs Screenings, Usual Care
- Where
- United States
- Volunteers
- 7,645 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Early Life Adversity, Caregiver Stress
The Resilience Clinic Evaluation
Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the…
- Trial name
- NCT05690256
- Testing
- Resilience Clinic, Enhanced primary care
- Where
- 4 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Preschool Age Children, Preschool Education
The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs
# Brief Summary The goal of this clinical trial is to learn if a occupational therapy-led trauma-informed care intervention can improve resilience, self-regulation, coping skills, and emotional health in preschoolers ages 2-4…
- Conditions
- Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health
- Trial name
- NCT07170605
- Testing
- Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Autism, Adverse Childhood Experience
A Two-Part Intervention to Target Cardiovascular Health
Obesity is one of the most common health conditions among autistic young people and its prevalence rises at faster rates for autistic-relative to non-autistic-individuals.
- Conditions
- Autism, Adverse Childhood Experience, Stress, Cardiovascular (CV) Risk
- Trial name
- NCT07673172
- Testing
- Lifestyle Medicine, Cognitive Behavioral Therapy (CBT), Lifestyle Medicine with CBT Group
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of California, Los Angeles
Aggression Childhood, Teen Dating Violence
Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services
The goal of this clinical trial is to learn if this intervention (Social Skills, Problem Solving, emotion Regulation, and psycho-Education on Trauma: A Trauma-Informed Peer Aggression and Teen Dating Violence Prevention Program…
- Trial name
- SPARE (NCT06769282)
- Testing
- Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Rhode Island Hospital
Adverse Childhood Experiences, Child Development
Testing a Scalable Model For ACEs-Related Care Navigation
The study is a randomized controlled trial of a telephone-based care coordination system for families who experienced Adverse Childhood Events (ACEs).
- Trial name
- NCT05567250
- Testing
- Behavioral: Telephone-based ACEs care coordination
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Adverse Childhood Experiences, Family Functioning
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among…
- Trial name
- NCT06821035
- Testing
- Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Autism Spectrum Disorder, Adverse Childhood Experiences
Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition
Using a metabolomics approach in combination with eye-tracking data, this research study proposes to gather evidence from two interrelated body systems (gut and brain) in order to assess how the microbiome is involved in stress…
- Conditions
- Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
- Trial name
- NCT06269614
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Child Abuse, Child Neglect
Child-Parent Psychotherapy - a Feasibility Study for Children in Foster Care
Children in foster care have an increased risk of exposure to adverse experiences during childhood and across the lifespan. In current studies of interventions children in foster care are often excluded, or they are too few to be…
- Conditions
- Child Abuse, Child Neglect, Post-Traumatic Stress Disorder in Children, Parent-Child Relations
- Trial name
- NCT04519229
- Testing
- Child-Parent Psychotherapy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Kronoberg County Council
Adverse Childhood Experiences
Family Resilience Initiative Research Program
University Le Bonheur Pediatric Specialists (ULPS) and Le Bonheur Community Health and Well-Being, Maternal Child Department, have started the Family Resilience Initiative (FRI) in the ULPS General Pediatrics Clinic.
- Trial name
- NCT04018404
- Testing
- FRI CLINICAL PROGRAM
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Adverse Childhood Experiences
ACEs Referral From PED
Adverse childhood experiences (ACEs) are traumatic exposures that can cause many negative health impacts across life. ACEs are common in patients who seek out care in pediatric emergency departments (PEDs); this is an opportunity…
- Trial name
- NCT06574633
- Testing
- In-person therapy, Telehealth therapy
- Where
- 4 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Emory University