Clinical trials: Acute Post Operative Pain
Pain
A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy
The purpose of this study is to evaluate effectiveness of a fixed combination of acetaminophen/naproxen sodium compared with placebo for reduction of pain when administered as multiple doses over a 48-hour period.
- Trial name
- NCT05868122
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination
- Where
- 4 sites in United States
- Volunteers
- 143 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Inguinal Hernia, Postoperative Pain
Lumbar ESP Block Versus TAP Block for Postoperative Pain Control in Children Undergoing Open Inguinal Hernia Repair
This study evaluates two ultrasound-guided nerve block techniques-Erector Spinae Plane Block (ESPB) and Transversus Abdominis Plane (TAP) block-for pain relief in children undergoing elective open inguinal hernia repair.
- Trial name
- NCT07916233
- Testing
- Ultrasound-guided Lumbar Erector Spinae Plane Block (ESPB), Ultrasound-guided Transversus Abdominis Plane (TAP) Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pain
Effect of Peritoneal Lavage With Clindamycin-gentamicin on Laparoscopic Sleeve Gastrectomy
A prospective, randomized study will be performed in patients undergoing laparoscopic sleeve gastrectomy (LSG) as bariatric procedure.
- Trial name
- NCT02479971
- Testing
- Clindamycin-gentamicin irrigation, Normal saline irrigation
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Elche
Post Operative Pain, Acute
Comparison Between the Analgesic Effect of Fascia Transversalis Block vs Caudal Block
Despite the growing interest in interfascial blocks and their successful use in pediatric surgeries, no previous randomized clinical trials have directly compared the analgesic efficacy, opioid-sparing effect, and safety profile…
- Trial name
- NCT07235475
- Testing
- Caudal Block Anesthesia, Fascia Transversalis Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative Confusion, Postoperative Delirium
Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
The goal of this randomized, double blinded study is to examine in children whether postoperative agitation can be reduced. The main question it aims to answer is Will optimized, monitor guided analgesic treatment and…
- Conditions
- Postoperative Confusion, Postoperative Delirium, Postoperative Pain, Acute, Postoperative Complications
- Trial name
- ANNA (NCT05785689)
- Testing
- Dexmedetomidine
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Appendicitis
A Comparison of UGBRS Block and Local Infiltration
In this research study, the investigators are trying to find out which of the two methods of injecting local anesthetics (at the site of the belly button cut or by ultrasound guided rectus sheath block) will provide better pain…
- Trial name
- NCT02352519
- Testing
- UGBRSB, Local Infiltration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pediatric Surgical Patients, Preemptive Epidural Analgesia
The Impact of Preemptive Epidural Analgesia on Acute Postoperative Pain in Pediatric Orthopedic Surgery
Management of postoperative pain is critical in the pediatric patients, however, safe and effective analgesia for pediatric surgical patients remains a challenge.
- Trial name
- NCT02813018
- Testing
- 0.2 ml/kg of 0.2% ropivacaine, 0.2mg/kg of Normal Saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Postoperative Pain
Effects of Perioperative Administration of Intravenous Lidocaine in Children Operated on for Acute Generalized Peritonitis
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay…
- Trial name
- NCT06051630
- Testing
- Lidocaine intravenous, Serum saline intravenous
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Université NAZI BONI
Postoperative Pain, Acute
Erector Spinae Plane Block Versus Quadratus Lumborum Block for Open Renal Surgeries in Children
Open renal surgeries are associated with significant postoperative pain; early control of the perioperative pain is associated with decrease of hemodynamic variations during the surgery, early mobilization, better quality of…
- Trial name
- NCT05386121
- Testing
- Ultrasound-guided Erector Spinae Plane Block, Ultrasound-guided Quadratus Lumborum Block, Ultrasound Machine
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Injury
Preemptive Analgesia in Cruciate Reconstruction
The aims of this study was to compare analgesic efficacy of preoperative administration of etoricoxib versus celecoxib for post-operative pain relief after arthroscopic anterior cruciate ligament reconstruction.
- Trial name
- NCT01017380
- Testing
- Celecoxib, etoricoxib
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University
Peritonitis; Acute, Acute Appendicitis
Retrospective Comparison Between AirSeal® and Standard Insufflation in Appendicular Peritonitis
The AirSeal System Valve-less Trocar is known to decrease postoperative pain, consumption of analgesics, operating time, and length of stay in adults during robotic and laparoscopic procedures.
- Conditions
- Peritonitis; Acute, Acute Appendicitis, Postoperative Pain, Laparoscopy
- Trial name
- APPAS (NCT06734494)
- Testing
- Laparoscopic appendectomy Laparoscopic appendectomy with Airseal or with standard insufflation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Destinval Christelle
Post Operative Pain, Acute
Ketamine Versus Magnesium as Analgesic Adjuvants in Pediatric Adenotonsillectomy
Adeno-tonsillectomy is one of the most common surgeries in children. The most common complication associated is postoperative pain.
- Trial name
- NCT05565664
- Testing
- Ketamine hydrochloride, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Analgesia, Pain, Acute
Assessment of Efficacy of Sacral Erector Spinae Plane Block for Postoperative Analgesia in Pediatric Rectal Biopsies
The purpose of this study is to evaluate how sacral erector spinae block changed the postoperative analgesia requirements in pediatric patients undergoing rectal biopsies under general anesthesia.
- Trial name
- NCT06362811
- Testing
- Sacral Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Acute Postoperative Pain, Motor Activity
Axillary Brachial Plexus Block Using 0.25% Bupivacaine Versus Using 0.19%Bupivacaine in Pediatrics
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage and inadequate intraoperative pain assessment and management .Axillary brachial plexus block provides motor and…
- Trial name
- NCT05386095
- Testing
- 0.25%Bupivacaine Axillary brachial plexus block, 0.19% Bupivacaine Axillary brachial plexus block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Opioid Use, Unspecified
Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in Children.
The overall objective of this study is to evaluate strategies to reduce unused opioids prescribed for pediatric acute post-surgical pain management.
- Trial name
- NCT04219397
- Testing
- Medication take back, Medication home disposal
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Pain, Acute
Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management
Compare between the analgesic efficacy of diclofenac sodium and ketorolac tromethamine in post-tonsillectomy pain management.and Compare between the effect of diclofenac sodium and ketorolac tromethamine on post-tonsillectomy…
- Trial name
- NCT03178539
- Testing
- diclofenac, ketorolac
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University