Clinical trials: Acute Diarrhea
Diarrhea, Chronic Diarrhea
Safety, Tolerability and Preliminary Efficacy of Lenodiar Pediatric in Diarrhea
Evaluation of the efficacy of a treatment with Actitan-F, a natural molecular complex of tannins (from Agrimony and Tormentil) and flavonoids (Chamomile) in a pediatric population of children affected by acture/prolonged/chronic…
- Conditions
- Diarrhea, Chronic Diarrhea, Acute Diarrhea, Diarrhea, Infantile
- Trial name
- NCT03598010
- Testing
- Actitan-F (7dd), Actitan-F (28dd)
- Volunteers
- 240 people
- Sponsor
- Aboca Spa Societa' Agricola
Acute Watery Diarrhea
Safety and Efficacy of Racecadotril in Children With Acute Watery Diarrhea
Acute watery diarrhea is a common cause of illness and hospitalization in children under five years of age, particularly in developing countries.
- Trial name
- NCT07392931
- Testing
- Racecadotril
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Punjab Rangers Teaching Hospital Lahore
Healthy Volunteers
Effects of Bifidobacterium Longum BB536 on Incidence of Acute Diarrhea and/or Respiratory- Related Illnesses in Children
This project aims to study the benefits of probiotics namely Bifidobacterium longum BB536 in prevention of acute diarrhea and/or respiratory-related illnesses, which are found common among children in Malaysia aged from 2 to 6…
- Trial name
- NCT02434042
- Testing
- BB536
- Where
- Malaysia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Acute Gastroenteritis
Lactose-free Milk in Infants With Acute Diarrhea in a Developing Country
The purpose of this study is to determine whether lactose-free milk will shorten the diarrhea duration and decrease its severity in formula-fed infants presenting to the Emergency Department (ED) or pediatric clinics with acute…
- Trial name
- NCT02246010
- Testing
- Lactose- free milk
- Where
- Lebanon
- Volunteers
- 6 people
- Sponsor
- American University of Beirut Medical Center
Acute Diarrhea, Acute Respiratory Infection
Improving Nighttime Access to Care and Treatment (Part 2)
Children in resource-limited settings who develop illness at night are often isolated from pre-emergency care, resulting in progression to an emergency because families are forced to wait until morning to seek care.
- Conditions
- Acute Diarrhea, Acute Respiratory Infection, Acute Febrile Illness
- Trial name
- INACT2 (NCT03943654)
- Testing
- MotoMeds Healthline- illness assessment and treatment recommendation for non-emergent cases by telephone
- Where
- Haiti
- Volunteers
- 391 people
- Sponsor
- University of Florida
Acute Diarrhea
Probiotics for the Prevention of Antibiotic-Associated Diarrhea
In North America, one of the most common reasons for hospitalization in previously healthy children is for the treatment of infections with antibiotics.
- Trial name
- PAID (NCT02817165)
- Testing
- Probiotic (BioK+)
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- The Hospital for Sick Children
Severe Acute Malnutrition, Persistent Diarrhea
Trial of Rice-Based F-75 in Severe Malnutrition & Persistent Diarrhea in Children (SAM-RICE Study)
The goal of this study is to find out if a rice-based version of the F-75 therapeutic food helps children with severe acute malnutrition (SAM) and persistent diarrhea recover better than the standard commercial F-75.
- Conditions
- Severe Acute Malnutrition, Persistent Diarrhea, Children
- Trial name
- SAM-RICE (NCT07070856)
- Testing
- WHO-recommended standard therapeutic milk used for stabilization phase in SAM), HO-recommended Rice based therapeutic milk used for stabilization phase in SAM)
- Where
- 2 sites in Pakistan
- Volunteers
- 320 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Acute Diarrhea, Acute Gastroenteritis
Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants
The purpose of this study is to determine the effect of zinc in acute watery diarrhea in children. The investigators will evaluate the effect of product versus placebo.
- Trial name
- NCT01571856
- Testing
- Zinc Sulfate
- Where
- Bolivia
- Volunteers
- 52 people
- Sponsor
- Centro Pediatrico Albina de Patino
Diarrhoea
Effectiveness of Smecta in the Treatment of Acute Diarrhoea in Children
The purpose of this study is to evaluate the effectiveness of Smecta at decreasing stool weight, when compared to placebo, in the treatment of acute diarrhoea in children.
- Trial name
- NCT00352716
- Testing
- Smecta (Diosmectite), duration of treatment - 7 days
- Where
- 13 sites in Peru
- Volunteers
- 300 people
- Sponsor
- Ipsen
Acute Gastroenteritis, Diarrhea
Surveillance Study of Acute Gastroenteritis in Hospitalized Children in Rural Area in Lebanon
Acute gastroenteritis is a common cause of hospitalization in children with significant socioeconomic burden on the health community, we will follow in this observational and analytical study the admitted cases of acute…
- Conditions
- Acute Gastroenteritis, Diarrhea, Rotavirus
- Trial name
- SAGE (NCT02177799)
- Where
- Lebanon
- Volunteers
- 150 people
- Sponsor
- Shaikh Ragheb Harb Hospital
Gastroenteritis, Vomiting
Oral Disintegrating Ondansetron Tablet to Reduce Vomiting From Gastroenteritis in a Pediatric Emergency Department
The objectives of the study were to determine whether ondansetron treatment would reduce: the amount of vomiting in the emergency department; the need for intravenous rehydration; and the need for hospitalization.
- Conditions
- Gastroenteritis, Vomiting, Diarrhea, Dehydration
- Trial name
- NCT00120744
- Testing
- Ondansetron Oral Disintegrating Tablet
- Sponsor
- The Hospital for Sick Children
Radiation-induced Diarrhoea in Prostate and Rectal Cancer
Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer
Approx. 80% of patients with prostate and rectal cancer who receive radiation therapy (RT) experience acute radiation-induced diarrhea (RID).
- Trial name
- PRECANU (NCT05684432)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Acute Gastroenteritis, Viral Illness
Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis
A phase III, double-blind, parallel-design, randomized, placebo-controlled trial to compare multi-dose oral Ondansetron with placebo as treatment for vomiting secondary to acute gastroenteritis (AGE), after Emergency Department…
- Conditions
- Acute Gastroenteritis, Viral Illness, Vomiting, Diarrhea
- Trial name
- DOSE-AGE (NCT03851835)
- Testing
- Ondansetron Oral Solution
- Where
- 6 sites in Canada
- Volunteers
- 1,030 people
- Sponsor
- University of Calgary
Acute Diarrhea
Fecal Calprotectin: Cheap Marker for Diagnosing Acute Infectious Diarrhea
Every year more than 4 billion cases of diarrhea occur worldwide culminating in about 2.5 million deaths, almost all in the developing nations.
- Trial name
- NCT00429325
- Where
- 2 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Diarrhea
Zinc Dosing Trial - Does Dose Reduction Reduce Side Effects But Retain Efficacy in Diarrhoea Management
Diarrhoea continues to be a major cause of child deaths. Current treatment of acute watery diarrhoea includes oral rehydration solution (ORS), zinc and continued feeding.
- Trial name
- ZTDT (NCT03078842)
- Testing
- Zinc tablets, 20 mg per day, Zinc tablets, 10 mg per day, Zinc tablets, 5 mg per day
- Where
- 2 sites in India, Tanzania
- Volunteers
- 4,500 people
- Sponsor
- Ayesha De Costa
Acute Otitis Media
Bio-Kult Infantis® in AAD Prevention in Infants
Background: antibiotic-associated diarrhoea (AAD) is defined as an acute inflammation of the intestinal mucosa associated to the administration of antibiotics.
- Trial name
- NCT03516409
- Testing
- Biokult
- Where
- Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Probiotics International Ltd.
Acute Diarrhea
Efficacy and Safety of Saccharomyces Boulardii in Treatment of Acute Diarrhea in Children Aged 6 Months to 5 Years Old
This study aimed to evaluate the effectiveness of saccharomyces-based treatment in children with acute diarrhea aged 6 months to 5 years compared to children treated with standard methods.
- Trial name
- NCT07813182
- Testing
- Saccharomyces Boulardii Probiotic Supplement, The child will be treated with standard method
- Where
- Vietnam
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Diarrhea
Impact of the Nutritional Product PTM202 on Acute and Long-Term Recovery From Childhood Diarrheal Disease
This trial will assess the impact of the nutritional product PTM202 on childhood diarrhea in Guatemalan children. The product is based on cow-milk colostrum and egg.
- Trial name
- NCT02385773
- Testing
- PTM202, Enfamil Puramino
- Where
- 2 sites in Guatemala
- Volunteers
- 321 people
- Sponsor
- University of Colorado, Denver
Gastroenteritis Acute, Gastrointestinal Symptoms
Diagnostic PCR Panel in Children With Acute Gastrointestinal Symptoms
This investigator-initiated randomized controlled trial compares the clinical impact of real time PCR of fecal samples in children with acute gastrointestinal symptoms at a pediatric emergency room.
- Conditions
- Gastroenteritis Acute, Gastrointestinal Symptoms, Abdominal Pain/ Discomfort, Vomiting in Infants and/or Children
- Trial name
- RealCAGI RCT (NCT07280624)
- Testing
- Multiplex PCR gastrointestinal panel
- Volunteers
- 526 people
- Sponsor
- University of Oulu
Gastroenteritis, Gastritis
BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis
Randomized, Placebo-Controlled, Phase 3 Trial of RHB-102 (BEKINDA) (Ondansetron 24 mg Bimodal Release Tablets) for Acute Gastroenteritis.
- Trial name
- GUARD (NCT02246439)
- Testing
- RHB-102
- Where
- 26 sites in United States
- Volunteers
- 330 people
- Sponsor
- RedHill Biopharma Limited