Clinical trials: Abscess
Abscess
The Effect of Wound Irrigation With Irrisept on Abscess Healing (Irrisept UF Study)
The purpose of this study was to evaluate the safety and effectiveness of Irrisept compared to standard of care treatment of skin and soft tissue infections in the form of abscesses.
- Trial name
- NCT04957732
- Testing
- Standard of Care (SoC), Irrisept Delivery System
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Irrimax Corporation
Abscess
Management of Skin and Soft Tissue Abscesses in Pediatric Patients After Incision and Drainage
The purpose of the study is to compare rates of cure of abscesses with and without antibiotic treatment after incision and drainage.
- Trial name
- NCT00691600
- Testing
- oral trimethoprim/sulfamethoxazole
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Perforated Appendicitis
Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis
The objective of this study is to scientifically evaluate two different management strategies for perforated appendicitis. The hypothesis is that early discharge with oral antibiotic therapy may result in a dramatic decrease in…
- Trial name
- NCT00462020
- Testing
- 5 days of IV antibiotics (ceftriaxone and metronidazole), Home with oral antibiotics when eating (ampicillin/clavulanic acid)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Children's Mercy Hospital Kansas City
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
Abscess, Fracture
Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children
The purpose of the study is to find the dose of rapidly administered ketamine in 3 different pediatric age groups (2-5, 6-11 and 12-17) for abscess drainage and fracture reduction.
- Trial name
- NCT01669642
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Washington University School of Medicine
Staphylococcal Skin Infection, Abscess
Individualized vs. Household MRSA Decolonization
The purpose of this research study is to compare the effectiveness of commonly used decolonization treatments (application of mupirocin antibiotic ointment to the nose and bleach baths) when performed by individuals with a…
- Conditions
- Staphylococcal Skin Infection, Abscess, Furunculosis, Staphylococcus Aureus
- Trial name
- HOME2DS (NCT01814371)
- Testing
- 2% mupirocin ointment, Bleach Bath (dilute), Hygiene Protocol
- Where
- United States
- Volunteers
- 474 people
- Sponsor
- Washington University School of Medicine
Abscesses, Furunculosis
The Natural History of Community-Associated MRSA Infections and Decolonization Strategies
The purpose of this study is to determine the natural history of community-associated Staphylococcus aureus infections in both adult and pediatric patients by monitoring the rate of recurrent infections in those colonized with S.
- Conditions
- Abscesses, Furunculosis, Staphylococcus Aureus, Staphylococcal Skin Infections
- Trial name
- StLStaRS (NCT00513799)
- Testing
- Mupirocin ointment, Chlorhexidine showers, Bleach baths (dilute)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Abscess
The Effect Of Wound Irrigation With Irrisept™ Delivery System On Abscess Healing In Patients Presenting To The Emergency Department
The purpose of this study is to determine if wound cleansing and irrigation using the IRRISEPT Chlorhexidine Gluconate(CHG)solution, applying a given volume with a pressurized stream, will improve the outcome for infected…
- Trial name
- NCT01302548
- Testing
- IRRISEPT, Usual Care
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Florida
Staphylococcal Infection
Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus
The purpose of this clinical trial is to evaluate 2 different antibiotics, drugs that fight bacteria, [clindamycin (CLINDA) and trimethoprim-sulfamethoxazole (TMP-SMX)] and wound care for the outpatient management of…
- Trial name
- NCT00730028
- Testing
- Trimethoprim-sulfamethoxazole, Clindamycin
- Where
- 6 sites in United States
- Volunteers
- 1,310 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Cholecystitis, Empyema of Gallbladder
Effects of Drainage in Laparoscopic Cholecystectomy
During laparoscopic surgery for an acutely inflamed gallbladder, most surgeons routinely insert a drain. However, no consensus has been reached regarding the need for drainage in these cases, and the use of a drain remains…
- Conditions
- Acute Cholecystitis, Empyema of Gallbladder, Abscess of Gallbladder
- Trial name
- NCT02027402
- Testing
- Laparoscopic cholecystectomy with drain insertion
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Seoul St. Mary's Hospital
Liver Neoplasms, Adenoma
Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.
Medical records are reviewed to obtain information about the use of a MRI diagnostic imaging agent (contrast agent) called Primovist/Eovist in children older than 2 months and less than 18 years.
- Conditions
- Liver Neoplasms, Adenoma, Carcinoma, Liver Abscess
- Trial name
- NCT01043523
- Testing
- Gadoxetic Acid Disodium (Eovist, BAY86-4873)
- Where
- 9 sites in United States, Italy and 3 more
- Volunteers
- 52 people
- Sponsor
- Bayer
Complicated Appendicitis, Perforated Appendicitis
Antibiotic Duration in Post-appendectomy Abscess
This is a randomized study of patients 2-17 years old who are diagnosed with perforated appendicitis and develop an abscess after laparoscopy that is subsequently drained.
- Trial name
- NCT03795194
- Testing
- ampicillin/clavulanate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Phoenix Children's Hospital
Abscess
Antibiotics Versus Placebo in the Treatment of Abscesses in the Emergency Department
The purpose of this study is to determine if there is a difference between an antibiotic, trimethoprim-sulfamethoxazole versus placebo in healing outcomes of soft tissue abscesses following incision and drainage.
- Trial name
- NCT00867789
- Testing
- Trimethoprim-sulfamethoxazole, Sugar pill
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Staphylococcal Skin Infections, Abscesses
Staphylococcus Aureus Decolonization Study
The purpose of this study is to determine whether measures to eliminate the Staph germ from the skin of the index patient (with a special ointment and soap) are more effective when performed by everyone in the household rather…
- Conditions
- Staphylococcal Skin Infections, Abscesses, Furunculosis, Staphylococcus Aureus
- Trial name
- SuDS (NCT00731783)
- Testing
- 2% Mupirocin Ointment, 4% Chlorhexidine liquid soap, Hygiene protocol
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Washington University School of Medicine
Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection
Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Abscess
The purpose of this study is to better understand why children develop methicillin-resistant Staphylococcus aureus (MRSA) skin infections that require surgical drainage and whether antibiotics are helpful after the infection is…
- Conditions
- Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection, Skin Abscess
- Trial name
- NCT01498744
- Testing
- Oral Clindamycin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Staphylococcal Infection, Abscess
Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections
The purpose of this study is to help define the role of antibiotics in the treatment of pediatric skin infections caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA).
- Conditions
- Staphylococcal Infection, Abscess, Staphylococcal Skin Infection, Folliculitis
- Trial name
- NCT00352612
- Testing
- clindamycin, cephalexin
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aaron Chen
Community-Acquired Staphylococcus Aureus
Prevention of Recurrent Infections Caused by Community Acquired Staphylococcus Aureus (CA-SA) in Children
The primary purpose of this study is to determine if adding bleach baths to routine ways for prevention of Staph infections is helpful. The amount added is a very weak amount.
- Trial name
- NCT00901316
- Testing
- Routine Measures Group, Bleach Bath Group (Bleach plus routine measures)
- Where
- 2 sites in United States
- Volunteers
- 987 people
- Sponsor
- Baylor College of Medicine
Skin Diseases, Infectious
Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management
The purpose of this study is to determine if antibiotics are required in the management of skin abscess following incision and drainage.
- Trial name
- NCT00679302
- Testing
- Trimethoprim-sulfamethoxazole
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- St. Louis University
Pneumonia, Lung Abscess
Special Use-Result Surveillance of Unasyn-S (Kit) for Intravenous Use - A Surveillance on High-dose (>6 g Daily) Administration -
The purpose of the survey is to study the followings under practical use, regarding the safety and effectiveness in high-dose administration (exceeding 6 g per day) of UNASYN-S and UNASYN-S KIT for intravenous use (UNASYN). 1.
- Conditions
- Pneumonia, Lung Abscess, Peritonitis
- Trial name
- NCT01793688
- Testing
- Sulbactam Sodium/Ampicillin Sodium
- Volunteers
- 982 people
- Sponsor
- Pfizer