Clinical trials: Abortion, Induced
Medication Abortion, Telemedicine
TeleMAb Retrospective Cohort Study
The objective of this study is to evaluate whether there are different clinical outcomes and unscheduled follow-ups between in-person and telemedicine medication abortion, and to better understand patients' experiences with…
- Trial name
- NCT07405294
- Testing
- Telemedicine Medication Abortion
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Columbia University
Abortion Early
Very Early Medical Abortion
The research question begin addressed by this study is "Is Very Early Medical Abortion (VEMA - before a pregnancy is visible on ultrasound scan) as effective as medical abortion when performed later and an intrauterine pregnancy…
- Trial name
- VEMASCOT (NCT03989869)
- Testing
- Immediate treatment
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Uterine Cervical Incompetence
Dilapan-S Osmotic Dilator in Pre-induction of Labor
Non-interventional prospective data collection designed to evaluate clinical outcome on the efficacy of the use of Dilapan-S in the indication of labor pre-induction in women with/without a history of Caesarean section.
- Trial name
- NCT02098382
- Testing
- Dilapan-S
- Where
- Czechia
- Volunteers
- 125 people
- Sponsor
- Medicem International CR s.r.o.
Infections, Papillomavirus
Post-marketing Safety Study to Assess the Risk of Spontaneous Abortions in Women Exposed to Cervarix Residing in UK
This study will assess the risk of spontaneous abortion during weeks 1-23 and weeks 1-19 of gestation, respectively, and other pregnancy outcomes, in an exposed cohort, i.e.
- Trial name
- NCT01905462
- Testing
- Data Collection, Cervarix
- Where
- United Kingdom
- Volunteers
- 1,046 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Abortion in First Trimester, Abortion Early
A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial
Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion.
- Conditions
- Abortion in First Trimester, Abortion Early, Decision Aid, Clinical Decision-making
- Trial name
- NCT05182008
- Testing
- Decision aid, Usual care
- Where
- Canada
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Medical Abortion
The Acceptability and Feasibility of an Alternative to Routine Follow-up Visit After Medical Abortion in Vietnam
This trial will compare the efficacy and acceptability of post-medical abortion follow-up by assigning women to either 1) alternative follow-up via routine semi-quantitative pregnancy test and a self-administered follow-up…
- Trial name
- NCT01150422
- Testing
- Alternative follow-up
- Where
- 4 sites in Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Outpatient Medical Abortion With Mifepristone and Misoprostol Through 77 Days of Gestation
To demonstrate non-inferiority of the efficacy of 200 mg mifepristone followed in 24 to 48 hours by 800 µg buccal misoprostol in outpatient medical abortion services among women 71-77 days' compared to women 64-70 days' LMP.
- Trial name
- XXGA (NCT02314754)
- Testing
- Mifepristone followed by misoprostol 24-48 hours later
- Where
- 8 sites in United States, Azerbaijan and 3 more
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Retained Products of Conception Post Abortion
Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
We speculate that the use of combined oral contraceptives may be a possible solution to promote the management of retained pregnancy products versus expectant management.
- Trial name
- NCT03230825
- Testing
- Oral contraceptive, Expectant management
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Induced; Abortion, Nonmedical
Comparison of Laminaria and Misoprostol for Cervical Preparation Before Second Trimester Surgical Abortion
This study compares the effectiveness of cervical preparation before second trimester abortion using laminaria versus vaginal Misoprostol.
- Trial name
- NCT01678703
- Testing
- Laminaria, MedGyn Products, Inc. USA., Misoprostol
- Where
- Israel
- Volunteers
- 84 people
- Sponsor
- Wolfson Medical Center
Pregnancy
Evaluation of Telemedicine Medical Abortion Service in Ecuador
This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks…
- Trial name
- NCT06270056
- Testing
- Misoprostol
- Where
- 3 sites in Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Induced
Mifepristone Plus Misoprostol Versus Misoprostol Alone for 2nd Trimester Abortion (14 - 21 Weeks Last Menstrual Period (LMP))
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00969982
- Testing
- mifepristone+misoprostol
- Where
- 2 sites in Moldova, Tunisia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Missed Abortion
Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage
Termination of pregnancy is an important subject that has complex and emotional controversies. The most common time of termination of pregnancy is the mid-trimester which has two-thirds of all serious abortion-related…
- Trial name
- NCT03584698
- Testing
- Misoprostol 100Mcg Tab, Evening Primrose Oil 1000 MG
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Assiut University
Infertility, Intellectual Disability
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
Chromosomal aberrations are major causes of developmental disorders (Intellectual disability (ID), multiple congenital anomalies (MCA), autism spectrum disorders (ASD)) as well as reproductive disorders (RD) in particular…
- Conditions
- Infertility, Intellectual Disability, Malformation, Miscarriage
- Trial name
- CHROMAPS (NCT05290051)
- Testing
- Optical Genome Mapping (Bionano®), Longread sequencing (Nanopore®)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Miscarriage, Parodontitis
PERIodontal Disease, Microbiota and Miscarriage
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and…
- Trial name
- PERI2M (NCT06576622)
- Testing
- biological sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Contraception
RCT: Can a Single Counseling Phone Call Improve Contraception After an Abortion?
Hypothesis: Use of an effective contraceptive six weeks after abortion will be higher in the treatment group than in the control group.
- Trial name
- PPR (NCT01199952)
- Testing
- Treatment group: receives counseling phone call intervention
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
Study of Immediate Start of Progestin Contraceptives in Medical Abortion
This study will compare immediate to post-abortion start of two progestin-based contraceptives (DMPA and etonorgestrel implants) among women having first trimester medical abortion who wish to use that method for post-abortion…
- Trial name
- Quickstart (NCT01902485)
- Testing
- Timing of Contraceptive Initiation in Medical Abortion
- Where
- 8 sites in United States, Mexico
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Self-Assessment of Medical Abortion Outcome Using Serial Multi-level Pregnancy Tests
This study aims to investigate the effectiveness and acceptability of the multi-level pregnancy test for self-assessment of abortion outcomes, without a routine provider contact.
- Trial name
- NCT02570204
- Testing
- Self-assessment
- Where
- 3 sites in United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Recurrent Pregnancy Loss(RPL)
Genomics and Microbiome Investigation in Cases of Recurrent Pregnancy Losses
Recurrent pregnancy losses (RPL) are characterized by the occurrence of more than one spontaneous pregnancy loss. It is caused by different known factors, but about half of the cases remain without an explanation.
- Trial name
- NCT06604338
- Testing
- Exome test, Microbiota analysis
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Missed Miscarriage
Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Miscarriage is the most common complication of pregnancy. As many as 15-25% of pregnancies end in miscarriage, and the number of miscarriages in England is estimated to be approximately 125,000 per year.
- Trial name
- MifeMiso (NCT03065660)
- Testing
- Mifepristone, Oral, 200 Mg
- Where
- 28 sites in United Kingdom
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Pregnancy, COVID-19
SARS-COV-2 VARIANTS' EFFECT ON PREGNANCY AND LONG-TERM OUTCOMES AMONG PREGNANT WOMEN AND THEIR NEWBORNS IN ESTONIA
The main aim of the study is to describe the possible impacts of SARS-CoV-2 and its various genotypes on pregnancy and long-term outcomes among pregnant women and their newborns in Estonia.
- Conditions
- Pregnancy, COVID-19, Post-COVID / Long-COVID, Newborn Health
- Trial name
- NCT06806696
- Testing
- COVID-19 infection
- Where
- Estonia
- Volunteers
- 60,739 people
- Sponsor
- University of Tartu