Clinical trials: ACT
Exercise, Physical Activity
The Active by Choice Today (ACT) Trial to Increase Physical Activity
The increasing prevalence of obesity in U.S. children and adolescents is a major health threat to our society, especially among minority and low social economic status (SES) populations.
- Conditions
- Exercise, Physical Activity, Obesity
- Trial name
- ACT (NCT01028144)
- Testing
- Physical Activity Program, General Health Program
- Where
- United States
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cystic Fibrosis
Improving Outcome Measures For Adult CF ACT Trials
This is a randomised controlled cross-over trial involving adult cystic fibrosis (CF) patients from the Royal Brompton Hospital, London investigating outcome measures used in airway clearance trials.
- Trial name
- NCT02721498
- Testing
- Airway clearance session using the Active Cycle of Breathing Techniques (ACBT), Rest period
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Autism Spectrum Disorder
ACT Combined Yoga for Parental Burnout in Parents with Autistic Children
OBJECTIVE: To explore the intervention effect of ACT combined with a yoga intervention program on parenting burnout in parents with ASD.
- Trial name
- NCT06348992
- Testing
- Acceptance commitment therapy and yoga, Active Comparator: Mental Health Education Group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Harbin Medical University
Depressive Disorder, Sleep Disturbance
iACT & iTBS for Sleep Quality in Depressed Adolescents
This study evaluated whether combining an internet-delivered Acceptance and Commitment Therapy program with intermittent theta burst stimulation improves subjective sleep quality in adolescents with depressive disorders and sleep…
- Trial name
- NCT07807072
- Testing
- Internet-Delivered Acceptance and Commitment Therapy, Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Central China Normal University
Malaria
Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria
The purpose of this study is to compare the efficacy and safety of the fixed combination of pyronaridine artesunate (Pyramax®, PA) (180:60 mg) with that of standard chloroquine therapy in children and adults with acute…
- Trial name
- NCT00440999
- Testing
- Pyronaridine artesunate, Chloroquine
- Where
- 5 sites in Cambodia, India and 2 more
- Volunteers
- 456 people
- Sponsor
- Medicines for Malaria Venture
Rudeness/Incivility, Aggression or Violence Against Healthcare Workers in an Ophthalmic Emergencies Unit.
Antisocial Behavior on Healthcare Professionals in an Emergency Unit.
At the hospital, the attacks against health professionals are becoming commonplace, making working conditions difficult. The ophthalmological emergencies are a perfect testing ground to evaluate the effectiveness of a series of…
- Trial name
- PREVURGO (NCT02015884)
- Where
- France
- Volunteers
- 58,465 people
- Sponsor
- Hospices Civils de Lyon
Healthy Participants Study
ACT-based EMI in College Students
This study aims to evaluate the acceptability and effectiveness of a transdiagnostic, Acceptance and Commitment Therapy (ACT)-based ecological momentary intervention (EMI) among college students.
- Trial name
- NCT06843395
- Testing
- ACT-based ecological momentary intervention, Mood monitoring
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Falciparum Malaria
Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients
The primary objective of this phase III clinical study is to compare the efficacy and safety of the fixed combination of pyronaridine artesunate (Pyramax®, PA) with that of the combination of mefloquine plus artesunate (MQ + AS)…
- Trial name
- NCT00403260
- Testing
- Pyronaridine - artesunate, Mefloquine plus artesunate
- Where
- 9 sites in Burkina Faso, Cambodia and 5 more
- Volunteers
- 1,271 people
- Sponsor
- Medicines for Malaria Venture
Asthma
To Determine the Validity of the ACT in an Adolescent Population With Persistent Asthma
To determine the measurement profiles of the asthma control test (ACT) in an adolescent population with persistent asthma.
- Trial name
- ACT2 (NCT02662413)
- Testing
- Validation of Asthma Control Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of North Carolina, Chapel Hill
Detention Under the Mental Health Act
Advance Choice Document Implementation
Advance Choice Documents (ACDs) are statements of preferences for mental health care and treatment made when service users have capacity to do so. This is done with their care team and others as desired, e.g.
- Trial name
- ACDI (NCT07284368)
- Testing
- Advance Choice Document Implementation
- Where
- United Kingdom
- Volunteers
- 374 people
- Sponsor
- King's College London
Alpha-1 Antitrypsin Deficiency
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study
The Alpha-1 Coded Testing (ACT) Study was established to study genetic testing and outcomes of individuals at risk for alpha-1 antitrypsin deficiency.
- Trial name
- ACT (NCT00500123)
- Testing
- Alpha-1 Antitrypsin Genotype
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Florida
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
Fever, Malaria
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar
The purpose of this study is to study the effectiveness of wide scale RDT use at the primary health care level in previously high malaria endemic area during malaria pre-elimination phase for improved targeting of anti-malarial…
- Trial name
- RDTACT (NCT01002066)
- Where
- Tanzania
- Volunteers
- 3,890 people
- Sponsor
- Karolinska University Hospital
Anger, Aggression
Anger Control Therapy (ACT) With RAGE-Control: An Outpatient Videogame-assisted Therapy for the Treatment of Anger
The purpose of this study is to determine whether adding an interactive biofeedback video game to anger control cognitive behavioral therapy is an effective and feasible treatment.
- Trial name
- NCT01551732
- Testing
- ACT, ACT with RAGE-Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gonzalez-Heydrich, Joseph, M.D.
Health Behavior
Using Emails and Personalized Phone Calls to Increase Affordable Care Act Marketplace Enrollment Among Households Losing Medicaid
Since its passage in 2010, the Affordable Care Act (ACA) has helped reduce the uninsured rate to record lows, but changes in insurance coverage over time, known as churn, remain a concern.
- Trial name
- NCT05327712
- Testing
- Control group, Email only, Phone only
- Where
- United States
- Volunteers
- 2,173 people
- Sponsor
- Office of Evaluation Sciences
Malaria, Falciparum
Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, Indonesia
This is a prospective, open label, randomised controlled trial to assess the safety and efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum…
- Trial name
- NCT02325180
- Testing
- Dihydroartemisinin-Piperaquine, Artemether-lumefantrine
- Where
- 3 sites in Indonesia
- Volunteers
- 338 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Malaria,Falciparum
"Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania"
This clinical trial evaluates the advantage of prolonging the therapeutic life span of Artemether-lumefantrine from 3 days to 6 days, and addition of single low dose of Primaquine 0.25mg/kg.
- Trial name
- ALU-PQ (NCT03241901)
- Testing
- Artemether-Lumefantrine Tab 20-120mg, Primaquine Phosphate 0.25 mg/kg
- Where
- 2 sites in Tanzania
- Volunteers
- 280 people
- Sponsor
- Muhimbili University of Health and Allied Sciences
Asthma Childhood
This Study Aims to Compare Asthma Control in Children Monitored With FeNO Against a Historical Cohort Without FeNO. Secondary Objectives Include Evaluating Associations Between FeNO Levels, ACT/C-ACT Scores, Eosinophil Counts, FEV1%, ICS Adherence, and Exacerbation Frequency.
This study aims to evaluate whether incorporating FeNO monitoring into routine pediatric asthma care improves clinical outcomes relative to a historical cohort managed without FeNO
- Trial name
- NCT07788534
- Testing
- FENO, PFT
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Accute Falciparum Malaria
Artemether-lumefantrine Resistance Monitoring in Children With Uncomplicated Plasmodium Falciparum Malaria in Mali
Background: Malaria is a disease caused by a parasite. People get malaria if they are bitten by an parasite-infected mosquito. A drug called artemether-lumefantrine (AL) can treat malaria.
- Trial name
- NCT02645604
- Where
- Mali
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Traumatic Articular Cartilage Defects in the Knee Joint
Phase III Study to Evaluate Safety and Effectiveness of NOVOCART 3D Plus vs. Microfracture in Knee Cartilage Defects
In this phase 3 clinical trial, a second generation ACI (autologous chondrocyte implantation technique) is compared to standard of care therapy (microfracture) to treat traumatic cartilage defects of the knee for efficacy and…
- Trial name
- N3D (NCT01656902)
- Testing
- NOVOCART® 3D plus, Microfracture
- Where
- 35 sites in Austria, Czechia and 8 more
- Volunteers
- 263 people
- Sponsor
- Tetec AG