Hamstring TightnessNCT07919184
Eccentric Exercise Versus Neurodynamic Sliding Technique for Hamstring Flexibility and Lower-Limb Strength
A study testing The hamstring eccentric exercises and The neurodynamic sliding technique in people with Hamstring Tightness, run by King Saud University at 1 site in India.
Trial summary
This randomized comparative trial evaluated the effects of a six-week, supervised intervention comparing eccentric exercise to the neurodynamic sliding technique in 42 sedentary young women with hamstring tightness. Read more about this study
- Who is it for?
- Ages 18 to 25 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Hamstring Tightness
- What is being tested?
- The hamstring eccentric exercises and The neurodynamic sliding technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 siteIndia
- Study dates
- 7 Aug 2024to 18 Feb 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Sedentary young women
- 18 to 25 years
- Absence of major metabolic comorbidity,
- Active knee extension loss of at least 20 degrees,
- Unilateral or bilateral hamstring tightness with full knee range of motion
Who cannot join
- Prior injury,
- Neurological dysfunction,
- Spinal pathology,
- Regular sports participation;
- A history of musculotendinous hamstring injury;
- A history of lumbar disc herniation;
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- Limited joint mobility of the hip, knee, or ankle,
- Rheumatoid arthritis;
- Anterior cruciate ligament tear without surgical correction;
- Abnormal psychological conditions;
- Radiating low back pain;
- Congenital, traumatic, or acquired (pathological or infective) spinal conditions;
- Malignancy;
- Neck trauma.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Eccentric Exercise Versus Neurodynamic Sliding Technique for Hamstring Flexibility and Lower-Limb Strength in Young Women With Hamstring Tightness: A Randomized Comparative Trial
This randomized comparative trial evaluated the effects of a six-week, supervised intervention comparing eccentric exercise to the neurodynamic sliding technique in 42 sedentary young women with hamstring tightness. Both interventions were completed without adverse events and produced significant improvements in hamstring flexibility (active knee extension) and lower-limb strength. Although the eccentric exercise group achieved significantly greater strength gains and greater flexibility improvements over time compared to the neurodynamic sliding group, the overall between-group differences in flexibility across time points were not statistically significant and were confounded by baseline imbalances. Consequently, while both approaches are effective for this population, eccentric exercise demonstrated greater overall benefits, though the between-group flexibility advantages warrant cautious interpretation.
- Conditions
- Hamstring Tightness
- Being tested
- The hamstring eccentric exercises, The neurodynamic sliding technique
- Keywords
- Hamstring tightness, eccentric exercise, neurodynamic sliding technique, flexibility, muscle strength
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
The hamstring eccentric exercisesOther
To perform hamstring eccentric exercises in supine with the lower extremities fully extended, a 1-meter TheraBand was wrapped around the foot and held in both hands. Participants actively flexed the hip while resisting eccentrically with the hamstrings for about 5 seconds, then slowly extended the hip.
The neurodynamic sliding techniqueOther
To perform the neurodynamic sliding technique, participants sat with a slouched posture and hands behind their backs, then alternated cervical extension with ankle dorsiflexion and knee extension, followed by cervical flexion with ankle plantarflexion and knee flexion.
| Study group | Role | What they receive |
|---|---|---|
| The eccentric exercise group | Experimental | In the eccentric exercise group the participants performed a TheraBand-assisted eccentric hamstring exercise three times weekly for a total duration of 6 weeks. Receives: Other: The hamstring eccentric exercises |
| The neurodynamic sliding technique group | Active comparator | In the neurodynamic sliding technique group the participants performed a a seated slump-based neurodynamic sliding sequence three times weekly for a total duration of 6 weeks. Receives: Other: The neurodynamic sliding technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
Active Knee Extension Test
Participants lay supine with the hip and knee flexed to 90 degrees, actively extended the knee while maintaining hip position, and the popliteal angle was calculated as 180 degrees minus the measured knee extension angle, with lower values indicating greater flexibility. Normal Range for this outcome is 15 degrees - 25 degrees. Lower values indicate better outcome.
Measured: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.
Lower-limb strength
Participants stood on the platform of Back-Leg-Chest dynamometer, with slight knee flexion, grasped the handle at knee level, and performed a maximal isometric lift for three seconds. Normal ranges: 220 to 330 lbs. Higher values indicate better outcome.
Measured: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Nov 2026
- Study start7 Aug 2024
- Primary completion10 Jan 2025
- Study completion18 Feb 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hamstring TightnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 42 participants (actual)
Sponsor and investigators
- Lead sponsor
- King Saud University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Masood Khan, King Saud University
- Investigators
- Kavitha Jayaraman, Principal investigator, AWH Special College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07919184
- Sponsor's protocol ID
- AWH/EC/04/2024
- Status last verified
- Oct 2026
- First submitted
- 31 Oct 2026
- Last updated
- 5 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Eccentric Exercise Versus Neurodynamic Sliding Technique for Hamstring Flexibility and Lower-Limb Strength in Young Women With Hamstring Tightness: A Randomized Comparative Trial
- ClinicalTrials.gov ID
- NCT07919184
- Acronym / sponsor ID
- AWH/EC/04/2024
- Conditions
- Hamstring Tightness
- Keywords
- Hamstring tightness, eccentric exercise, neurodynamic sliding technique, flexibility, muscle strength
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 42 participants (actual)
- Lead sponsor
- King Saud UniversityUniversity, hospital or other
- Study start
- 7 Aug 2024 (actual)
- Primary completion
- 10 Jan 2025 (actual)
- Study completion
- 18 Feb 2025 (actual)
- First posted
- 5 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized comparative trial evaluated the effects of a six-week, supervised intervention comparing eccentric exercise to the neurodynamic sliding technique in 42 sedentary young women with hamstring tightness. Both interventions were completed without adverse events and produced significant improvements in hamstring flexibility (active knee extension) and lower-limb strength. Although the eccentric exercise group achieved significantly greater strength gains and greater flexibility improvements over time compared to the neurodynamic sliding group, the overall between-group differences in flexibility across time points were not statistically significant and were confounded by baseline imbalances. Consequently, while both approaches are effective for this population, eccentric exercise demonstrated greater overall benefits, though the between-group flexibility advantages warrant cautious interpretation.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| The eccentric exercise group | Experimental | Other: The hamstring eccentric exercisesIn the eccentric exercise group the participants performed a TheraBand-assisted eccentric hamstring exercise three times weekly for a total duration of 6 weeks. |
| The neurodynamic sliding technique group | Active comparator | Other: The neurodynamic sliding techniqueIn the neurodynamic sliding technique group the participants performed a a seated slump-based neurodynamic sliding sequence three times weekly for a total duration of 6 weeks. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Sedentary young women
- 18 to 25 years
- Absence of major metabolic comorbidity,
- Active knee extension loss of at least 20 degrees,
- Unilateral or bilateral hamstring tightness with full knee range of motion
Key exclusion criteria (14 listed)
- Prior injury,
- Neurological dysfunction,
- Spinal pathology,
- Regular sports participation;
- A history of musculotendinous hamstring injury;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| The hamstring eccentric exercisesTo perform hamstring eccentric exercises in supine with the lower extremities fully extended, a 1-meter TheraBand was wrapped around the foot and held in both hands. Participants actively flexed the hip while resisting eccentrically with the hamstrings for about 5 seconds, then slowly extended the hip. | Other | The eccentric exercise group |
| The neurodynamic sliding techniqueTo perform the neurodynamic sliding technique, participants sat with a slouched posture and hands behind their backs, then alternated cervical extension with ankle dorsiflexion and knee extension, followed by cervical flexion with ankle plantarflexion and knee flexion. | Other | The neurodynamic sliding technique group |
Primary outcome
Active Knee Extension Test
Time frame: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.
Participants lay supine with the hip and knee flexed to 90 degrees, actively extended the knee while maintaining hip position, and the popliteal angle was calculated as 180 degrees minus the measured knee extension angle, with lower values indicating greater flexibility. Normal Range for this outcome is 15 degrees - 25 degrees. Lower values indicate better outcome.
Lower-limb strength
Time frame: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.
Participants stood on the platform of Back-Leg-Chest dynamometer, with slight knee flexion, grasped the handle at knee level, and performed a maximal isometric lift for three seconds. Normal ranges: 220 to 330 lbs. Higher values indicate better outcome.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Nov 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kavitha Jayaraman principal investigator
AWH Special College
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing The hamstring eccentric exercises and The neurodynamic sliding technique in people with Hamstring Tightness, run by King Saud University at 1 site in India.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 14 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in India. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Active Knee Extension Test (time frame: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Nov 2026.