AphasiaLCSANCT07889778
Learning to Communicate Successfully Approach for Urdu Speaking Patients With Chronic Aphasia
A study testing Learning to Communicate Successfully Approach (LCSA) in people with Aphasia, run by University of Lahore at 2 sites in Pakistan.
Trial summary
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Aphasia
- What is being tested?
- Learning to Communicate Successfully Approach (LCSA)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesPakistan
- Study dates
- 17 Jul 2025to 10 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult male and female patients
- Mild or moderate level on the Glasgow Coma Scale (GCS)
- Diagnosed with chronic aphasia
- Passed hearing and vision screening
Who cannot join
- Patients with impaired levels of consciousness
- Patients speaking a language other than Urdu in the acute stage
Trial locations and contacts
2 sites in 1 country.
Pakistan2 sites
University of Lahore Teaching Hospital
Lahore, Punjab Province, 54792
Combined Military Hospital (CMH), Lahore, Pakistan
Lahore, Punjab Province, 54800
About this study
Official title: Development and Validation of Manual for Learning to Communicate Successfully Approach (LCSA) in Urdu Speaking Patients With Chronic Aphasia
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia. Aphasia is a language disorder that can affect speaking, understanding, reading, writing, and everyday communication, commonly following stroke or other neurological conditions. The LCSA addresses communication difficulties while also considering participation in daily life, communication partners, the communication environment, and personal and psychosocial factors. The study evaluates the feasibility, applicability, and outcomes of the LCSA approach in Urdu-speaking adults with chronic aphasia.
Read the detailed description
Aphasia is an acquired language disorder that can affect an individual's ability to speak, understand spoken language, read, and write. People living with chronic aphasia may experience persistent communication difficulties that affect participation in everyday activities, relationships, and quality of life.
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA) manual for Urdu-speaking adults with chronic aphasia. The LCSA is a culturally sensitive, comprehensive intervention approach that addresses communication difficulties from multiple perspectives. The approach incorporates impairment-based intervention, participation-focused intervention, communication partner training, communication environment modification, and personal and psychosocial factors.
The LCSA manual's development included a qualitative phase with input from speech-language pathologists and caregivers, followed by expert review and face-validity assessment. The team then implemented the manual with Urdu-speaking adults with chronic aphasia to evaluate its applicability and outcomes.
The quantitative phase uses a one-group pre-test-post-test design to evaluate changes in communication and related functional outcomes following implementation of the LCSA. Participants undergo assessment before and after the intervention using standardized and study-related outcome measures. The findings are intended to provide evidence regarding the validity, applicability, and potential effectiveness of the LCSA manual for Urdu-speaking adults with chronic aphasia.
The study is intended to contribute to culturally and linguistically appropriate aphasia rehabilitation by providing speech-language pathologists with a structured intervention approach specifically developed for Urdu-speaking individuals with chronic aphasia.
- Conditions
- Aphasia
- Being tested
- Learning to Communicate Successfully Approach (LCSA)
- Keywords
- Aphasia, Rehabilitation, Speech-Language Pathology, Communication, Neurological Rehabilitation, Learning to Communicate Successfully Approach, LCSA
- Medical subject headings
- Aphasia, Communication
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Learning to Communicate Successfully Approach (LCSA)Behavioural
The Learning to Communicate Successfully Approach (LCSA) is a structured, culturally sensitive communication intervention developed for Urdu-speaking adults with chronic aphasia. The approach integrates impairment-based intervention, participation-focused intervention, communication partner training, communication environment modification, and personal and psychosocial support. A speech-language pathologist delivers the intervention according to the LCSA manual.
| Study group | Role | What they receive |
|---|---|---|
| Learning to Communicate Successfully Approach (LCSA) | Experimental | Participants with chronic aphasia receive the Learning to Communicate Successfully Approach (LCSA), a structured, culturally sensitive communication intervention designed to address communication impairment, participation in everyday communication, communication partner involvement, the communication environment, and personal and psychosocial factors. Assess outcomes before and after the intervention. Receives: Behavioral: Learning to Communicate Successfully Approach (LCSA) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Aphasia Severity and Language Function
Aphasia severity and language function will be assessed using the Quick Aphasia Battery (QAB). The QAB summary scores range from 0 to 10, with a minimum score of 0 and a maximum score of 10. Higher scores indicate better language function, whereas lower scores indicate greater language impairment.
Time Frame: Baseline and immediately after completion of the intervention.
Measured: Baseline and immediately after completion of the intervention.
Secondary outcomes (1)
Impact of Aphasia on Quality of Life
The impact of aphasia on quality of life will be assessed using the Aphasia Impact Questionnaire-21 (AIQ-21). The total score ranges from a minimum of 0 to a maximum of 84. Higher scores indicate a greater impact of aphasia on the individual's life, whereas lower scores indicate a lesser impact and a better outcome.
Time Frame: Baseline and immediately after completion of the intervention.
Measured: Baseline and immediately after completion of the intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Oct 2026
- Study start17 Jul 2025
- Primary completion10 Mar 2026
- Study completion10 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AphasiaStudies of the same condition, open and under way.
- More trials run by University of LahoreThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- This single-group, pre-test-post-test interventional study includes participants with chronic aphasia who receive the Learning to Communicate Successfully Approach (LCSA). We assess outcomes before and after the intervention to evaluate changes associated with the LCSA.
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Abdoul Aziz Fall, PhD, Principal investigator, University of CyberjayaMUHAMMAD AHMED, PhD Medical Sciences, Principal investigator, University of Cyberjaya
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07889778
- Sponsor's protocol ID
- 575/24
- Acronym
- LCSA
- Status last verified
- Sep 2026
- First submitted
- 16 Oct 2026
- Last updated
- 29 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share individual participant data with other researchers. The research team will retain participant-level data and handle it confidentially in accordance with the approved research ethics requirements.
Study at a glance
From the registry record, last updated by the sponsor on 29 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development and Validation of Manual for Learning to Communicate Successfully Approach (LCSA) in Urdu Speaking Patients With Chronic Aphasia
- ClinicalTrials.gov ID
- NCT07889778
- Acronym / sponsor ID
- LCSA / 575/24
- Conditions
- Aphasia
- Keywords
- Aphasia, Rehabilitation, Speech-Language Pathology, Communication, Neurological Rehabilitation, Learning to Communicate Successfully Approach, LCSA
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- University of LahoreUniversity, hospital or other
- Study start
- 17 Jul 2025 (actual)
- Primary completion
- 10 Mar 2026 (actual)
- Study completion
- 10 Mar 2026 (actual)
- First posted
- 22 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia. Aphasia is a language disorder that can affect speaking, understanding, reading, writing, and everyday communication, commonly following stroke or other neurological conditions. The LCSA addresses communication difficulties while also considering participation in daily life, communication partners, the communication environment, and personal and psychosocial factors. The study evaluates the feasibility, applicability, and outcomes of the LCSA approach in Urdu-speaking adults with chronic aphasia.
Detailed description
Aphasia is an acquired language disorder that can affect an individual's ability to speak, understand spoken language, read, and write. People living with chronic aphasia may experience persistent communication difficulties that affect participation in everyday activities, relationships, and quality of life.
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA) manual for Urdu-speaking adults with chronic aphasia. The LCSA is a culturally sensitive, comprehensive intervention approach that addresses communication difficulties from multiple perspectives. The approach incorporates impairment-based intervention, participation-focused intervention, communication partner training, communication environment modification, and personal and psychosocial factors.
The LCSA manual's development included a qualitative phase with input from speech-language pathologists and caregivers, followed by expert review and face-validity assessment. The team then implemented the manual with Urdu-speaking adults with chronic aphasia to evaluate its applicability and outcomes.
The quantitative phase uses a one-group pre-test-post-test design to evaluate changes in communication and related functional outcomes following implementation of the LCSA. Participants undergo assessment before and after the intervention using standardized and study-related outcome measures. The findings are intended to provide evidence regarding the validity, applicability, and potential effectiveness of the LCSA manual for Urdu-speaking adults with chronic aphasia.
The study is intended to contribute to culturally and linguistically appropriate aphasia rehabilitation by providing speech-language pathologists with a structured intervention approach specifically developed for Urdu-speaking individuals with chronic aphasia.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- This single-group, pre-test-post-test interventional study includes participants with chronic aphasia who receive the Learning to Communicate Successfully Approach (LCSA). We assess outcomes before and after the intervention to evaluate changes associated with the LCSA.
| Arm | Type | Receives |
|---|---|---|
| Learning to Communicate Successfully Approach (LCSA) | Experimental | Behavioral: Learning to Communicate Successfully Approach (LCSA)Participants with chronic aphasia receive the Learning to Communicate Successfully Approach (LCSA), a structured, culturally sensitive communication intervention designed to address communication impairment, participation in everyday communication, communication partner involvement, the communication environment, and personal and psychosocial factors. Assess outcomes before and after the intervention. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adult male and female patients
- Mild or moderate level on the Glasgow Coma Scale (GCS)
- Diagnosed with chronic aphasia
- Passed hearing and vision screening
Key exclusion criteria (2 listed)
- Patients with impaired levels of consciousness
- Patients speaking a language other than Urdu in the acute stage
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Learning to Communicate Successfully Approach (LCSA)The Learning to Communicate Successfully Approach (LCSA) is a structured, culturally sensitive communication intervention developed for Urdu-speaking adults with chronic aphasia. The approach integrates impairment-based intervention, participation-focused intervention, communication partner training, communication environment modification, and personal and psychosocial support. A speech-language pathologist delivers the intervention according to the LCSA manual. | Behavioural | Learning to Communicate Successfully Approach (LCSA) |
Primary outcome
Aphasia Severity and Language Function
Time frame: Baseline and immediately after completion of the intervention.
Aphasia severity and language function will be assessed using the Quick Aphasia Battery (QAB). The QAB summary scores range from 0 to 10, with a minimum score of 0 and a maximum score of 10. Higher scores indicate better language function, whereas lower scores indicate greater language impairment. Time Frame: Baseline and immediately after completion of the intervention.
1 secondary outcome
Impact of Aphasia on Quality of Life
Time frame: Baseline and immediately after completion of the intervention.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Oct 2026.
- Individual participant dataSharing planned: No. There is no plan to share individual participant data with other researchers. The research team will retain participant-level data and handle it confidentially in accordance with the approved research ethics requirements.
Related trials for Aphasia
Not yet recruiting
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia (BG-Aphasia-01)
Expressive Aphasia, Aphasia Following Cerebral Infarction
Recruiting
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
Aphasia, Stroke
Not yet recruiting
Restoring Speech With an Intracortical Neuroprosthesis for Post-Stroke Agrammatic Aphasia (BG-Aphasia-02)
Aphasia, ALS
Not yet recruiting
Cerebellar Brain Stimulation Plus Language Therapy for People at Risk of Poor Aphasia Recovery After Stroke
Aphasia, Stroke
Not yet recruitingObservational study
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Stroke, Ischemic Stroke
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Abdoul Aziz Fall, PhD principal investigator
University of Cyberjaya
MUHAMMAD AHMED, PhD Medical Sciences principal investigator
University of Cyberjaya
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Learning to Communicate Successfully Approach (LCSA) in people with Aphasia, run by University of Lahore at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Aphasia Severity and Language Function (time frame: Baseline and immediately after completion of the intervention.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Oct 2026.