Lyme BorreliosisNCT07871578
Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain
An observational study of Lyme Borreliosis and Fibromyalgia, run by Central Hospital, Nancy, France at 1 site in France.
Trial summary
Chronic pain is a major symptom shared by several medical conditions. This study focuses on five well-defined chronic diseases : Lyme Borreliosis (LB), Post-Acute COVID-19 Syndrome (PACS or "long COVID"), fibromyalgia, endometriosis, and rheumatoid arthritis. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Lyme Borreliosis, Fibromyalgia, Rheumatoid Arthritis (RA)
- How many people
- 501 participants
- Where
- 1 siteFrance
- Study dates
- 17 Mar 2025to 3 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: The following patient-reported conditions were selected: Lyme borreliosis, Post acute COVID-19 Syndrome, fibromyalgia, endometriosis and rheumatoid arthritis. Diagnostic accuracy was not verified. Posts were included whenever patients reported suffering from one of these conditions.
Who may be able to join
- posts had to be published on four platforms: Instagram®, Facebook®, Twitter®/X®, and patient forums
- they had to be publicly available (i.e., from open accounts);
- they had to include one or more of the following keywords in French equivalents: "fibromyalgia", "Lyme", "long COVID" (for PACS, because this term is not used by patients), "endometriosis", and "rheumatoid arthritis"
- posts had to be written in French.
Who cannot join
- none
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Is Lyme Borreliosis Experienced Differently From Other Chronic Pain Conditions? An Infodemiological Analysis of Symptoms, Treatments and Healthcare Pathways
Chronic pain is a major symptom shared by several medical conditions. This study focuses on five well-defined chronic diseases : Lyme Borreliosis (LB), Post-Acute COVID-19 Syndrome (PACS or "long COVID"), fibromyalgia, endometriosis, and rheumatoid arthritis. Although all of these conditions are associated with chronic pain, they differ in several important aspects, justifying their choice for a comparison.
The overall objective of this study was to describe the symptoms, treatments, and healthcare pathways associated with these five conditions, as reported by patients on social media platforms and online forums. The specific objectives were to compare PTLDS with the four other conditions across the following aspects: (i) Incompatible symptoms reported by patients; (ii) Different components of pain : physical, emotional, and social; (iii) Healthcare pathways; and (iv) Adherence to treatment recommendations.
- Conditions
- Lyme Borreliosis, Fibromyalgia, Rheumatoid Arthritis (RA), Post Acute COVID 19 Syndrome, Endometriosis
- Keywords
- Chronic Pain, Internet Use, Social Media, Arthritis, Rheumatoid, Post-Acute COVID-19 Syndrome, Fibromyalgia, Endometriosis, Post-Lyme Disease Syndrome, Lyme Disease
- Medical subject headings
- Lyme Disease, Fibromyalgia, Arthritis, Rheumatoid, Post-Acute COVID-19 Syndrome, Endometriosis, Chronic Pain, Post-Lyme Disease Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Lyme borreliosis | Patients describing themselves as having Lyme borreliosis | |
| Endometriosis | Patients describing on internet themselves as having Endometriosis | |
| Fibromyalgia | Patients describing on internet themselves as having Fibromyalgia | |
| Rheumatoid Arthritis | Patients describing on internet themselves as having Rheumatoid Arthritis | |
| Post-Acute COVID-19 Syndrome | Patients describing on internet themselves as having Post-Acute COVID-19 Syndrome |
What is being measured
The primary outcome is the main question the study is designed to answer.
symptoms
Comparison of symptoms reported by patients across all conditions in social media or forum posts not suggestive of the disease
Measured: Baseline
Treatments
Comparison of non-recommended treatments, reported by patients across all conditions in social media or forum posts
Measured: Baseline
healthcare pathways
Comparison of healthcare pathways, reported by patients across all conditions in social media or forum posts
Measured: Baseline
Biopsychosocial Model of Pain
Comparison of the different components of pain : physical, emotional, and social, reported by patients across all conditions in social media or forum posts
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Oct 2026
- Study start17 Mar 2025
- Primary completion3 Jul 2025
- Study completion3 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lyme BorreliosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Retrospective
- Enrolment
- 501 participants (actual)
Sponsor and investigators
- Lead sponsor
- Central Hospital, Nancy, France
- Sponsor type
- University, hospital or other
- Collaborators
- University Hospital, Strasbourg, France, University Grenoble Alps
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07871578
- Sponsor's protocol ID
- 2024PI086
- Status last verified
- Jul 2026
- First submitted
- 17 Sep 2026
- Last updated
- 13 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 13 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Is Lyme Borreliosis Experienced Differently From Other Chronic Pain Conditions? An Infodemiological Analysis of Symptoms, Treatments and Healthcare Pathways
- ClinicalTrials.gov ID
- NCT07871578
- Acronym / sponsor ID
- 2024PI086
- Conditions
- Lyme Borreliosis, Fibromyalgia, Rheumatoid Arthritis (RA), Post Acute COVID 19 Syndrome, Endometriosis
- Keywords
- Chronic Pain, Internet Use, Social Media, Arthritis, Rheumatoid, Post-Acute COVID-19 Syndrome, Fibromyalgia, Endometriosis, Post-Lyme Disease Syndrome
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 501 participants (actual)
- Lead sponsor
- Central Hospital, Nancy, FranceUniversity, hospital or other
- Collaborators
- University Hospital, Strasbourg, France, University Grenoble Alps
- Study start
- 17 Mar 2025 (actual)
- Primary completion
- 3 Jul 2025 (actual)
- Study completion
- 3 Jul 2025 (actual)
- First posted
- 13 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Chronic pain is a major symptom shared by several medical conditions. This study focuses on five well-defined chronic diseases : Lyme Borreliosis (LB), Post-Acute COVID-19 Syndrome (PACS or "long COVID"), fibromyalgia, endometriosis, and rheumatoid arthritis. Although all of these conditions are associated with chronic pain, they differ in several important aspects, justifying their choice for a comparison.
The overall objective of this study was to describe the symptoms, treatments, and healthcare pathways associated with these five conditions, as reported by patients on social media platforms and online forums. The specific objectives were to compare PTLDS with the four other conditions across the following aspects: (i) Incompatible symptoms reported by patients; (ii) Different components of pain : physical, emotional, and social; (iii) Healthcare pathways; and (iv) Adherence to treatment recommendations.
Study design
- Observational model
- Other
- Time perspective
- Retrospective
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| Lyme borreliosis | – | –Patients describing themselves as having Lyme borreliosis |
| Endometriosis | – | –Patients describing on internet themselves as having Endometriosis |
| Fibromyalgia | – | –Patients describing on internet themselves as having Fibromyalgia |
| Rheumatoid Arthritis | – | –Patients describing on internet themselves as having Rheumatoid Arthritis |
| Post-Acute COVID-19 Syndrome | – | –Patients describing on internet themselves as having Post-Acute COVID-19 Syndrome |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The following patient-reported conditions were selected: Lyme borreliosis, Post acute COVID-19 Syndrome, fibromyalgia, endometriosis and rheumatoid arthritis. Diagnostic accuracy was not verified. Posts were included whenever patients reported suffering from one of these conditions.
Key inclusion criteria (4 listed)
- posts had to be published on four platforms: Instagram®, Facebook®, Twitter®/X®, and patient forums
- they had to be publicly available (i.e., from open accounts);
- they had to include one or more of the following keywords in French equivalents: "fibromyalgia", "Lyme", "long COVID" (for PACS, because this term is not used by patients), "endometriosis", and "rheumatoid arthritis"
- posts had to be written in French.
Key exclusion criteria (1 listed)
- none
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
symptoms
Time frame: Baseline
Comparison of symptoms reported by patients across all conditions in social media or forum posts not suggestive of the disease
Treatments
Time frame: Baseline
Comparison of non-recommended treatments, reported by patients across all conditions in social media or forum posts
healthcare pathways
Time frame: Baseline
Comparison of healthcare pathways, reported by patients across all conditions in social media or forum posts
Biopsychosocial Model of Pain
Time frame: Baseline
Comparison of the different components of pain : physical, emotional, and social, reported by patients across all conditions in social media or forum posts
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Oct 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Lyme Borreliosis and Fibromyalgia, run by Central Hospital, Nancy, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
symptoms (time frame: Baseline). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Oct 2026.