Condition
Endometriosis Clinical Trials
Studies of endometriosis, matched by condition name and medical subject headings. Start with those open to enrolment.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 232Endometriosis
Phase Ia Trial of HHK001 Compared With Enantone in Patients With Endometriosis
The goal of this clinical trial is to find out how the study drug HHK001 compares to Enantone (an approved treatment for endometriosis) when given as a single 3.75 mg injection to participants with endometriosis.
- Trial name
- NCT07755956
- Testing
- Leuprorelin Acetate, Leuprorelin Acetate 3.75mg Injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhuhai Huahaikang Pharmaceutical Technology Co., Ltd.
Endometriosis, Microbiome Dysbiosis
Trial Evaluating Nutritional Fiber in Digestive Symptoms of Endometriosis
This study is a double-blind, randomized, placebo-controlled study that evaluates the safety and tolerability of a fiber-based dietary supplement and the mechanistic and structure-function effects of that supplement on the gut…
- Conditions
- Endometriosis, Microbiome Dysbiosis, Gastrointestinal Symptoms
- Trial name
- TEND (NCT07875062)
- Testing
- Fiber
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- LOAM Science
Endometriosis
Retinal Imaging for Systemic Inflammation in Endometriosis
There is increasing evidence that examining our eyes can tell us a lot of information about our health, and systemic diseases. Our plan is to compare the images taken of the back of eyes of women who have endometriosis with those…
- Trial name
- RISE (NCT07232485)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Endometriosis
Comparison Between the Effects of Implantable Gestrinone and Oral Dienogest in the Treatment of Endometriosis
This study aims to evaluate the effects of therapy with implantable Gestrinone compared to oral Dienogest in relieving complaints related to endometriosis.
- Trial name
- NCT06543550
- Testing
- Implantable gestrinone, Oral Dienogest
- Where
- 4 sites in Brazil
- Volunteers
- 70 people
- Sponsor
- Bio Meds Pharmaceutica Ltda
Endometriosis, Postoperative Pain
Postoperative Pain Trajectories After Endometriosis Surgery
The pain associated with endometriosis reflects a multifactorial pathophysiology combining peripheral nociception, central sensitisation and psychosocial factors.
- Conditions
- Endometriosis, Postoperative Pain, Pain Trajectories, Chronic Postsurgical Pain
- Trial name
- TRACK-ENDO (NCT07882498)
- Testing
- Perioperative quantitative sensory testing, questionnaire
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Endometrioma, Ultrasound Therapy; Complications
Effect of Alcohol Sclerotherapy on Pelvic Pain and Quality of Life in Women With Ovarian Endometriosis
The goal of this clinical trial is to evaluate whether ultrasound-guided alcohol sclerotherapy can improve pelvic pain and quality of life in women aged 18 to 45 diagnosed with ovarian endometriomas, compared to expectant…
- Conditions
- Endometrioma, Ultrasound Therapy; Complications, Quality of Life, Pelvic Pain
- Trial name
- ESCOMA (NCT06955221)
- Testing
- Ultrasound-guided aspiration and alcohol sclerotherapy
- Where
- 27 sites in Spain
- Volunteers
- 288 people
- Sponsor
- Hospital Universitari de Bellvitge
Endometriosis, Deep Infiltrating Endometriosis
Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis
The goal of this clinical trial is to learn whether [18F]AlF-FAPI-74 PET/CT can help detect endometriosis in adult women who are already scheduled for laparoscopy due to suspicion of deep infiltrating endometriosis or superficial…
- Conditions
- Endometriosis, Deep Infiltrating Endometriosis, Women, Superficial Peritoneal Endometriosis
- Trial name
- EM-FAPI (NCT07876648)
- Testing
- [18F]AlF-FAPI-74 PET/CT
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometriosis
Perioperative Esketamine Safety and Efficacy in Reducing Postoperative ENDometriosis PAIN (the ENDPAIN Trial): a Randomized Controlled Trial.
Endometriosis is a chronic condition affecting approximately 10% of women. It is frequently associated with persistent or recurrent pelvic and abdominal pain.
- Trial name
- ENDPAIN (NCT07881562)
- Testing
- Esketamine
- Volunteers
- 1,000 people
- Sponsor
- Region Skane
Deep Endometriosis
3D Modeling of Deep Endometriosis From Pelvic MRI
This retrospective monocentric study aims to assess the feasibility and clinical relevance of three-dimensional (3D) modeling of deep endometriosis lesions derived from pelvic MRI.
- Trial name
- ENDO-3D (NCT07864883)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Endometriosis
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
The study is a prospective, monocentric, randomized controlled, two-armed, pilot-study conducted at Department for Women's Health, Tuebingen, Germany.
- Trial name
- OVAPLAS (NCT07065214)
- Testing
- APC, Lap bipolar forceps
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Erbe Elektromedizin GmbH
Completed, with results posted
All –Endometriosis
Cardiovascular Disease Risk in Women With Endometriosis
To test the hypothesis that estrogen suppression impairs endothelial dysfunction in endometriosis.
- Trial name
- NCT03746535
- Testing
- Elagolix
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Yale University
Endometriosis, Pelvic Pain
Use of TENS Unit in the Management of Endometriosis Pain
The purpose of this study is see if Transcutaneous Electrical Nerve Stimulator (TENS) units help decrease endometriosis flare pain.
- Trial name
- NCT05348005
- Testing
- Ovira Transcutaneous Electrical Nerve Stimulation Unit
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Infertility, Endometriosis
Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis
A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate.
- Trial name
- PREGnant (NCT04173169)
- Testing
- Elagolix 200 MG
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- Yale University
Contraception
Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women With Uterine Fibroids or Endometriosis Who Are at Risk for Pregnancy
The purpose of this study is to assess the contraceptive efficacy of relugolix combination therapy.
- Trial name
- SERENE (NCT04756037)
- Testing
- Relugolix Combination Therapy
- Where
- 112 sites in United States, Puerto Rico
- Volunteers
- 1,164 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Endometriosis
A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain
The purpose of this global Phase 2 study is to determine the efficacy, safety, and tolerability of 3 dose levels of OG-6219 in pre-menopausal women between 18 and 49 years of age (inclusive), who have moderate to severe…
- Trial name
- ELENA (NCT05560646)
- Testing
- OG-6219
- Where
- 86 sites in United States, Belgium and 9 more
- Volunteers
- 354 people
- Sponsor
- Organon and Co