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CervicalNCT07790874

Effects of Oculomotor Exercises in Patients With Non Traumatic Cervical Dizziness

A study testing Sustained Natural Apophyseal Glides and Oculomotor exercises and Sustained Natural Apophyseal Glides in people with Cervical and Dizziness, run by Riphah International University at 1 site in Pakistan.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

To investigate the effects of oculomotor exercises on pain disability, dizziness and gaze stability in patients with non-traumatic cervical dizziness. Read more about this study

Who is it for?
Ages 20 to 40 years
Conditions the study is for
Cervical, Dizziness, Disability
What is being tested?
Sustained Natural Apophyseal Glides and Oculomotor exercises and Sustained Natural Apophyseal Glides
Could I receive a placebo?
No, everyone receives an active treatment
How many people
48 participants
Where
1 sitePakistan
Study dates
11 Aug 2026to 10 Oct 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 40 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Both Males and Females
  • Age between 20 and 40 years with nontraumatic cervical dizziness.
  • Patients experiencing symptoms of cervicogenic dizziness for at least 3 months (chronic cervicogenic dizziness)
  • Patients having a Numeric Pain Rating Scale (NPRS) score greater than or equal to 3
  • Patient with positive Flexion Rotation Test (FRT)
  • Cervical Torsion Test
  • Patients have never received oculomotor exercises and SNAGS before.

Who cannot join

  • History of trauma or recent surgery to the head, face, neck, or chest.
  • Diagnosis of central vertigo (e.g., brainstem or cerebellar pathology).
  • Presence of vestibular-origin vertigo, such as benign paroxysmal positional vertigo (BPPV).
  • Triage (Patients with traumatic cervical spine injury, Cervical arterial dysfunction and central vestibular disorders
  • Inability to perform exercises (e.g., due to cervical fracture)

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Imran Amjad, PhD contact

03324390125

imran.amjad@riphah.edu.pk

Pakistan1 site, 1 recruiting
  • Independent Hospital

    Faisalābad, Punjab Province, 38000

    Saba Rafiq, PhD, 03034045433, saba.rafiq@riphah.edu.pk

    Maria Irshad, MS OMPT

    Recruiting

Other trials in Pakistan

About this study

Official title: Effects of Oculomotor Exercises on Pain, Disability, Dizziness and Gaze Stability in Patients With Non Traumatic Cervical Dizziness

To investigate the effects of oculomotor exercises on pain disability, dizziness and gaze stability in patients with non-traumatic cervical dizziness.

Read the detailed description

A randomized controlled trial compared routine exercise with a combination of oculomotor exercises (OEs) and manual myofascial techniques (MFT) in patients with chronic non-specific neck pain (CNNP). Thirty-eight participants were randomly allocated into two groups, and both groups completed a six-week exercise program, while the intervention group additionally received OEs and manual MFT. Outcome measures included pain intensity, cervical range of motion (ROM), proprioception, kinesiophobia, and disability. Both groups showed significant improvements after treatment. However, the group receiving OEs and manual MFT demonstrated significantly greater improvements in cervical ROM, pain, disability, proprioception, and kinesiophobia compared to the routine exercise group. These findings suggest that adding OEs and manual MFT may enhance rehabilitation outcomes in patients with CNNP.

A comparative study evaluated manual therapy alone versus manual therapy combined with proprioception training in patients with cervicogenic dizziness (CGD) and chronic neck pain (CNP). Twenty participants were divided into two groups, with ten patients in each group. One group received manual therapy, while the other received manual therapy along with proprioception training. Outcome measures included joint position error sense (JPSE), smooth pursuit performance, Dizziness Handicap Inventory (DHI), and dizziness visual analogue scale (VAS). Both groups showed significant improvements following treatment; however, the combined therapy group demonstrated greater improvements in proprioception, eye movement control, dizziness severity, and disability. These findings indicate that adding proprioception training to manual therapy may provide superior therapeutic benefits for patients with CGD and CNP.

A randomized controlled trial investigated the effectiveness of tactile discrimination training (TDT) and OEs in individuals with chronic neck pain. Fifty-seven participants were randomly assigned to a TDT group, an OE group, or a control group that received no intervention. Both intervention groups underwent treatment three times per week for four weeks. Outcomes included pain intensity, neck pain-related disability, pressure pain thresholds, mechanical temporal summation of pain, and conditioned pain modulation. Significant improvements in pain intensity and neck-related disability were observed in both intervention groups compared with the control group. However, the OEs group demonstrated greater reductions in pain intensity and greater improvements in pressure pain thresholds than the TDT group. These findings suggest that both TDT and OEs may be effective in reducing pain and disability in patients with chronic neck pain, with OEs providing greater clinical benefits.

A multicenter randomized controlled trial compared three vestibular rehabilitation approaches in patients with unilateral peripheral vestibular dysfunction. Thirty-four participants were randomly assigned to customized vestibular rehabilitation therapy, generic vestibular rehabilitation therapy using Cawthorne-Cooksey exercises, or vestibulo-ocular reflex (VOR) adaptation exercises, with 23 participants completing the study. Outcomes included dizziness-related disability, balance, and visual stability. All three intervention groups demonstrated significant improvements following treatment. However, participants performing gaze stabilization exercises demonstrated greater reductions in dizziness-related disability and superior improvements in balance. These findings highlight the potential importance of gaze stabilization training as a component of vestibular rehabilitation, particularly in individuals with gaze stability impairments.

A randomized controlled trial compared the short- and long-term effects of two manual therapy approaches in patients with chronic cervicogenic dizziness. Eighty-six participants were randomly allocated to groups receiving SNAGs with self-SNAG exercises, passive joint mobilizations with ROM exercises, or a placebo intervention. Participants received treatment sessions over six weeks, with outcomes assessed up to 12 months. Both manual therapy groups demonstrated significant reductions in dizziness intensity and frequency, improvements in cervical ROM, and lower dizziness-related disability compared with the placebo group. The SNAG intervention produced greater improvements in cervical mobility and balance performance, while passive joint mobilization resulted in greater improvements in dizziness-related disability and pain reduction.

A randomized controlled study investigated the effects of oculomotor exercises in patients with chronic non-specific neck pain and associated visual complaints. Thirty-two participants were randomly allocated into two groups. The control group received stretching exercises for the sternocleidomastoid and anterior scalene muscles along with neck isometric exercises, whereas the experimental group received the same conventional treatment in addition to a structured OEs program consisting of saccadic eye movements, smooth pursuit exercises, convergence training, and gaze stabilization exercises. Outcomes included pain intensity, the Neck Disability Index (NDI), gaze stability, and visual symptoms. Significant improvements were observed in neck pain, disability, gaze stability, and visual complaints following the intervention. Improvements in eye-head coordination and sensorimotor control were also reported, suggesting that OEs may be beneficial for reducing pain and disability while improving gaze stability and visual function in patients with chronic neck pain.

A randomized controlled trial compared OEs combined with a cervical proprioceptive training program with cervical proprioceptive training alone in patients with chronic neck pain. Forty-eight patients were equally randomized into two groups. The intervention was applied three times per week for eight weeks, resulting in 24 sessions. Both groups demonstrated significant improvements in deep cervical flexor muscle activation and function. However, greater improvements in deep cervical flexor activation and functional outcomes were observed in the group receiving combined cervical proprioceptive and oculomotor training. These findings suggest that combining OEs with cervical proprioceptive training may provide additional benefits for improving clinical symptoms in patients with chronic neck pain.

A randomized controlled trial evaluated the efficacy of a self-exercise program in patients with cervicogenic dizziness. Thirty-two participants were randomly allocated to a self-exercise group or a control group. The self-exercise program included muscle strengthening, cervical mobilization, and osteopathic manipulative exercises performed at home, while the control group received no specific exercise intervention. Outcomes were assessed using the DHI, NDI, VAS, cervical ROM, and posturography tests. The self-exercise group demonstrated significantly greater improvements in dizziness-related disability and neck disability compared with the control group. However, no significant between-group differences were observed in pain intensity, cervical ROM, or balance measures.

A randomized controlled trial evaluated the effectiveness of adding sensorimotor training, including oculomotor and gaze stability exercises, to standard neck exercises in patients with chronic neck pain and dizziness. Seventy-two patients were randomly assigned to a standard neck exercise group or a combined sensorimotor training group. The intervention lasted ten weeks, and outcomes included neck pain intensity, disability, dizziness, balance, and gaze stability. The combined intervention demonstrated significantly greater improvements in dizziness, gaze stability, and balance compared with standard neck exercises. Greater reductions in neck pain and disability were also reported, suggesting that incorporating sensorimotor and oculomotor exercises may enhance rehabilitation outcomes in patients with chronic neck pain and associated dizziness.

A randomized controlled trial investigated the postural and clinical outcomes of SNAGs treatment in patients with cervicogenic dizziness. Eighty-nine patients were randomly assigned to either a SNAGs intervention group or a placebo group receiving a detuned laser. Both groups received six intervention sessions over four weeks. The SNAGs group demonstrated a significant reduction in perceived dizziness, neck disability, and pain, along with significant improvements in cervical ROM and selected posturographic parameters.

A randomized controlled trial investigated the short-term effects of a traction-manipulation protocol on dizziness intensity and disability in patients with cervicogenic dizziness. Forty participants were randomly assigned to an intervention group receiving traction-manipulation treatment or a control group that remained in a supine position. The intervention was delivered according to safety recommendations. Outcomes included dizziness intensity, pain intensity, DHI, cervical ROM, and balance, assessed at 48 hours and one month after treatment. The intervention group demonstrated significantly greater improvements in dizziness, neck pain, DHI scores, and upper cervical mobility compared with the control group at both follow-up periods. Postural stability also improved significantly in the intervention group at one month. These findings indicate that traction-manipulation may be effective for reducing dizziness and pain while improving cervical function and balance in patients with cervicogenic dizziness.

Being tested
Sustained Natural Apophyseal Glides and Oculomotor exercises, Sustained Natural Apophyseal Glides
Keywords
cervical dizziness, Oculomotor Exercises, Gaze Stability, Non Traumatic
Medical subject headings
Dizziness, Pain

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Sustained Natural Apophyseal Glides and Oculomotor exercisesOther

    Also called SNAGs

    Sustained Natural Apophyseal Glides: The patient sat upright and actively moved the head in the direction that provoked dizziness. The therapist applied a sustained anterior glide to the targeted C1 or C2 vertebra during the movement. The technique was performed initially for 3 repetitions and progressed to 6 repetitions, with gentle overpressure added as tolerated.

    Oculomotor Exercises: The intervention included saccadic eye movements, smooth pursuit training, gaze stabilization, and head-eye coordination exercises. These exercises were performed with the head and/or eyes moving in controlled directions to improve gaze stability, eye-head coordination, and sensorimotor control.

  • Sustained Natural Apophyseal GlidesOther

    he patient sat upright and actively moved the head in the direction that provoked dizziness. The therapist applied a sustained anterior glide to the targeted C1 or C2 vertebra during the movement. The technique was performed initially for 3 repetitions and progressed to 6 repetitions, with gentle overpressure added as tolerated.

Study groups in NCT07790874
Study groupRoleWhat they receive
Sustained Natural Apophyseal Glides and Oculomotor ExercisesExperimentalParticipants in Group A received moist heating pad, isometric exercises, Sustained Natural Apophyseal Glides, and oculomotor exercises including saccadic eye movements, smooth pursuit training, gaze stabilization, and head-eye coordination exercises.
Receives: Other: Sustained Natural Apophyseal Glides and Oculomotor exercises
Sustained Natural Apophyseal GlidesActive comparatorParticipants in Group B received standard physiotherapy, consisting of moist heating pad, isometric exercises, and Sustained Natural Apophyseal Glides
Receives: Other: Sustained Natural Apophyseal Glides

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Rating Scale of Gaze Stability

    Assesses gaze stability during head movements in sitting. It consists of three ratings: 0 indicates stable gaze, 1 indicates slightly irregular gaze stability, and 2 indicates repeatedly unstable gaze.

    Measured: 4 weeks

  2. Neck Disability index

    It comprises of 10 items; 7 related to daily living activities, 2 related to pain and 1 related to concentration. Each item is scored from 0 to 5. Total score is expressed as a percentage, with higher scores related to greater disability. It has high test-retest reliability (ICC = 0.978)

    Measured: 4 weeks

  3. Dizziness Handicap Inventory questionnaire

    A 25-item questionnaire assessing the functional, emotional, and physical effects of dizziness. Each item is scored as 0, 2, or 4, with a total score ranging from 0-100. Lower scores indicate less disability.

    Measured: 4th week

  4. Universal Goniometer

    A commonly used instrument for measuring cervical range of motion. It demonstrates high test-retest reliability and inter-rater reliability.

    Measured: 4 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted27 Aug 2026
  2. Study start11 Aug 2026
  3. Primary completion16 Sep 2026 (estimated)
  4. Study completion10 Oct 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
48 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07790874
Sponsor's protocol ID
REC/RCR&AHS/25/0128
Status last verified
Aug 2026
First submitted
25 Aug 2026
Last updated
27 Aug 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Sustained Natural Apophyseal Glides and Oculomotor exercises and Sustained Natural Apophyseal Glides in people with Cervical and Dizziness, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Imran Amjad, PhD (03324390125, imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Rating Scale of Gaze Stability (time frame: 4 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026.

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