Piriformis SyndromePiriformisNCT07674433
Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control Study
An observational study of Piriformis Syndrome and Pes Planus, run by Kahramanmaras Sutcu Imam University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate the relationship between Pes Planus and Piriformis Syndrome. The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing skills, have been diagnosed with piriformis syndrome, and voluntarily agree to participate. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Piriformis Syndrome, Pes Planus
- How many people
- 70 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jun 2026to 30 Aug 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing skills, have been diagnosed with piriformis syndrome (PS), and have voluntarily agreed to participate in the study and healthy group.
Who may be able to join
- Piriformis group
- 18-50 years old
- Clinical diagnosis of piriformis syndrome
- Positive FAIR test
- Piriformis tenderness on palpation Control group
- No piriformis syndrome
- No hip or lower back pain
- No neurological disease
Who cannot join
- Herniated disc (L5-S1 radiculopathy),
- previous hip surgery,
- inflammatory joint diseases
- neurological deficits…
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Kahramanmaraş Sütçü İmam Üniversitesi
Kahramanmaraş, onikişubat, 46100
About this study
The aim of this study is to investigate the relationship between Pes Planus and Piriformis Syndrome. The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing skills, have been diagnosed with piriformis syndrome, and voluntarily agree to participate. Participants will consist of individuals who have not previously undergone lumbar, hip, or lower extremity surgery and have not received injection therapy (corticosteroids, PRP) or any other physiotherapy program within the last three months.
Read the detailed description
In the literature, the effects of pes planus deformity on the lower extremity kinetic chain, especially its relationship with patellofemoral pain syndrome and non-specific low back pain, have been widely studied. However, case-control studies examining the direct relationship between increased tibial and femoral internal rotation caused by pes planus, the compensatory hypertrophy in the piriformis muscle which tries to stabilize the hip joint, and the resulting 'Piriformis Syndrome' are quite limited. This study aims to fill this gap in the literature by revealing the effect of foot postural disorders on deep gluteal region pathologies with clinical tests and to provide a biomechanical perspective to treatment protocols.
- Conditions
- Piriformis Syndrome, Pes Planus
- Keywords
- piriformis syndrome, pes planus, gluteal pain, pelvic pain, Navicular Drop
- Medical subject headings
- Piriformis Muscle Syndrome, Flatfoot, Pelvic Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| piriformis sendrom group | Investigation of pes planus in individuals with piriformis syndrome. | |
| healthy group | Investigation of pes planus in healthy individuals |
What is being measured
The primary outcome is the main question the study is designed to answer.
Foot Posture Index (FPI-6)
To comprehensively assess the static foot posture of the participants, the Foot Posture Index, which has proven reliability in the literature, will be used. During the assessment, the participant will be fixed in a relaxed standing position with their arms at their sides and facing forward, distributing their weight equally on both feet.
Measured: Baseline
Navicular Drop Test(NDT)
In evaluating the foot posture of the participants, the Navicular Drop Test (NDT), which has proven reliability and validity in the literature, will be used (10). The Navicular Drop Test is a clinical measurement method used to evaluate the arch structure and dynamic stability of the foot.The measurement process consists of two stages: First, with the foot unloaded, the height of this marked point from the ground is measured with a millimeter ruler or caliper. Then, the participant is asked to stand up without changing the foot position and distribute their body weight evenly between both legs. In this loaded position, the distance of the navicular tubercle from the ground is measured again. Finally, the difference between the height in the seated position and the height in the standing position is calculated. This drop, recorded in millimeters, indicates how much the foot flexes or collapses under load.
Measured: Baseline
Secondary outcomes (2)
Pain assessment
An algometer will be used to assess the pain threshold. The pressure-applying end of the algometric measuring device is blunt, not sharp, and has a diameter of 1 square centimeter. The pressure will be applied perpendicular to the midpoint of the muscle. Before the application, the individual will be informed and asked to report any pain felt while the pressure is gradually increased. The measurement will be taken while the individual is in a supine position. The value at which the individual first feels pain when pressure is applied will be recorded as the pain threshold. Three measurements will be taken at 1-minute intervals and their averages will be taken . The assessment will be made by applying pressure to the symphysis pubis.
Measured: Baseline
Demographic information
Demographic information of the individuals included in the study, such as age, height, body weight, body mass index, number of pregnancies, week of gestation, and the presence of any accompanying problems, will be recorded with a form.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jun 2026
- Study start1 Jun 2026
- Primary completion1 Aug 2026
- Study completion30 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Piriformis SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kahramanmaras Sutcu Imam University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Asiya Uzun, Kahramanmaras Sutcu Imam University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07674433
- Sponsor's protocol ID
- 2026/065
- Acronym
- Piriformis
- Status last verified
- Oct 2026
- First submitted
- 23 Jun 2026
- Last updated
- 2 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: patient data privacy
Study at a glance
From the registry record, last updated by the sponsor on 2 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control Study
- ClinicalTrials.gov ID
- NCT07674433
- Acronym / sponsor ID
- Piriformis / 2026/065
- Conditions
- Piriformis Syndrome, Pes Planus
- Keywords
- piriformis syndrome, pes planus, gluteal pain, pelvic pain, Navicular Drop
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Kahramanmaras Sutcu Imam UniversityUniversity, hospital or other
- Study start
- 1 Jun 2026 (actual)
- Primary completion
- 1 Aug 2026 (actual)
- Study completion
- 30 Aug 2026 (actual)
- First posted
- 29 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the relationship between Pes Planus and Piriformis Syndrome. The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing skills, have been diagnosed with piriformis syndrome, and voluntarily agree to participate. Participants will consist of individuals who have not previously undergone lumbar, hip, or lower extremity surgery and have not received injection therapy (corticosteroids, PRP) or any other physiotherapy program within the last three months.
Detailed description
In the literature, the effects of pes planus deformity on the lower extremity kinetic chain, especially its relationship with patellofemoral pain syndrome and non-specific low back pain, have been widely studied. However, case-control studies examining the direct relationship between increased tibial and femoral internal rotation caused by pes planus, the compensatory hypertrophy in the piriformis muscle which tries to stabilize the hip joint, and the resulting 'Piriformis Syndrome' are quite limited. This study aims to fill this gap in the literature by revealing the effect of foot postural disorders on deep gluteal region pathologies with clinical tests and to provide a biomechanical perspective to treatment protocols.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| piriformis sendrom group | – | –Investigation of pes planus in individuals with piriformis syndrome. |
| healthy group | – | –Investigation of pes planus in healthy individuals |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing skills, have been diagnosed with piriformis syndrome (PS), and have voluntarily agreed to participate in the study and healthy group.
Key inclusion criteria (8 listed)
- Piriformis group
Key exclusion criteria (4 listed)
- Herniated disc (L5-S1 radiculopathy),
- previous hip surgery,
- inflammatory joint diseases
- neurological deficits…
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Foot Posture Index (FPI-6)
Time frame: Baseline
To comprehensively assess the static foot posture of the participants, the Foot Posture Index, which has proven reliability in the literature, will be used. During the assessment, the participant will be fixed in a relaxed standing position with their arms at their sides and facing forward, distributing their weight equally on both feet.
Navicular Drop Test(NDT)
Time frame: Baseline
In evaluating the foot posture of the participants, the Navicular Drop Test (NDT), which has proven reliability and validity in the literature, will be used (10). The Navicular Drop Test is a clinical measurement method used to evaluate the arch structure and dynamic stability of the foot.The measurement process consists of two stages: First, with the foot unloaded, the height of this marked point from the ground is measured with a millimeter ruler or caliper. Then, the participant is asked to stand up without changing the foot position and distribute their body weight evenly between both legs. In this loaded position, the distance of the navicular tubercle from the ground is measured again. Finally, the difference between the height in the seated position and the height in the standing position is calculated. This drop, recorded in millimeters, indicates how much the foot flexes or collapses under load.
2 secondary outcomes
Pain assessment
Time frame: Baseline
Demographic information
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Nov 2026.
- Individual participant dataSharing planned: No. patient data privacy
Related trials for Piriformis Syndrome
Not yet recruitingPhase 2
Efficacy of Botulinum Toxin Versus Placebo on Pain and Health Related Quality of Life of Patients With Piriformis Muscle Syndrome
Piriformis Muscle Syndrome
Recruiting
Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome
Piriformis Syndrome
Recruiting
Comparative Effects of Post-Isometric Relaxation and Reciprocal Inhibition Techniques inPiriformis Syndrome
Piriformis Syndrome
Enrolling by invitation
Neural Gliders With and Without ESWT for Deep Gluteal Syndrome
Deep Gluteal Syndrome
Enrolling by invitation
Comparative Effects of the Bowen Technique With and Without Extracorporeal Shock Wave Therapy in Patients With Deep Gluteal Syndrome
Deep Gluteal Syndrome
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Piriformis Syndrome and Pes Planus, run by Kahramanmaras Sutcu Imam University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Foot Posture Index (FPI-6) (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Nov 2026.