Metabolic HealthNCT07673432
A Clinical Trial to Evaluate the Effects of a Plant-Based Liquid Supplement on Metabolic Health and Overall Well-Being
A study testing Plant-Based Liquid Supplement in people with Metabolic Health and Elevated Liver Enzymes, run by Biocol Labs at 1 site in United States.
Trial summary
This single-arm clinical trial will evaluate the effects of a plant-based liquid supplement on metabolic health, digestive health, skin health, and overall well-being. Twenty participants aged 40 to 60 years with elevated alanine transaminase (ALT) or aspartate transaminase (AST) levels will use the supplement daily… Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Metabolic Health, Elevated Liver Enzymes, Digestive Symptoms
- What is being tested?
- Plant-Based Liquid Supplement
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteUnited States
- Study dates
- 5 Jun 2025to 15 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age 40 to 60 years
- Elevated ALT or AST identified during prescreening blood testing
- Currently experiencing at least two of the following:
- Stomach discomfort, Constipation, Diarrhea, Heartburn, Bloating, Gas, Abdominal pain, Skin redness or pimples, Sugar cravings
- Willing to comply with study requirements
- Willing to discontinue supplements or herbal remedies targeting detoxification, digestive health, liver function, or skin health during the study
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- Willing to avoid starting new products, medications, or supplements targeting detoxification, digestive health, liver function, or skin health
- Willing to maintain normal diet, sleep patterns, and activity levels
- Generally healthy without uncontrolled chronic disease
- Resides in the United States
- Not participating in another research study during the study period
- Has access to a study partner to take study photographs
Who cannot join
- Severe digestive disorders including acid reflux, IBS, IBD, Crohn's disease, or gastrointestinal tract surgeries
- Liver disease
- Known allergy or hypersensitivity to study product ingredients Chronic conditions that would interfere with study participation, including oncological or psychiatric disorders
- Known severe allergic reactions
- Pregnant, breastfeeding, or attempting to conceive
- Unwilling to follow study procedures
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- Stopped hormonal birth control within the past month
- History of substance abuse
- Use of prescription diabetes medications, including GLP-1 receptor agonists such as Ozempic, Wegovy, or Mounjaro
Trial locations and contacts
1 site in 1 country.
About this study
This single-arm clinical trial will evaluate the effects of a plant-based liquid supplement on metabolic health, digestive health, skin health, and overall well-being. Twenty participants aged 40 to 60 years with elevated alanine transaminase (ALT) or aspartate transaminase (AST) levels will use the supplement daily for 90 days. Participants will complete questionnaires, provide body composition and waist circumference measurements, submit photographs, and undergo blood testing throughout the study. Outcomes include changes in metabolic biomarkers, body composition, digestive symptoms, skin health, and overall well-being.
- Conditions
- Metabolic Health, Elevated Liver Enzymes, Digestive Symptoms
- Being tested
- Plant-Based Liquid Supplement
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Plant-Based Liquid SupplementDietary supplement
A liquid dietary supplement containing choline bitartrate, zinc sulfate, manganese sulfate, artichoke leaf extract, fennel extract, rosemary leaf extract, L-arginine monohydrochloride, inositol, bromelain, papain, sorbitol, glycerin, artificial flavour, and potassium sorbate.
| Study group | Role | What they receive |
|---|---|---|
| Plant-Based Liquid Supplement | Experimental | Participants will consume one ampule of the study product diluted in approximately 8 ounces of water before the first meal of the day throughout the study period. Receives: Dietary Supplement: Plant-Based Liquid Supplement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Body Weight
Change in body weight measured using a Withings smart scale.
Measured: Baseline, Day 30, Day 60, and Day 90.
Change in Waist Circumference
Change in waist circumference measured using a tape measure and recorded in centimeters.
Measured: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in Body Fat Mass
Change in body fat mass measured using a Withings smart scale.
Measured: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in Lean Body Mass
Change in lean body mass measured using a Withings smart scale.
Measured: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in Visceral Fat Index
Change in visceral fat index measured using a Withings smart scale.
Measured: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in Alanine Aminotransferase (ALT)
Change in serum alanine aminotransferase concentration measured by hepatic function panel.
Measured: Baseline, Day 30, Day 60, and Day 90.
Change in Aspartate Aminotransferase (AST)
Change in serum aspartate aminotransferase concentration measured by hepatic function panel.
Measured: Baseline, Day 30, Day 60, and Day 90
Change in Alkaline Phosphatase (ALP)
Change in serum alkaline phosphatase concentration measured by hepatic function panel.
Measured: Baseline, Day 30, Day 60, and Day 90.
Change in Total Bilirubin
Change in serum total bilirubin concentration measured by hepatic function panel.
Measured: Baseline, Day 30, Day 60, and Day 90.
Change in Total Cholesterol
Change in serum total cholesterol concentration measured by lipid panel.
Measured: Baseline, Day 30, Day 60, and Day 90.
Secondary outcomes (5)
Change in Participant-Reported Bloating Severity
Change in participant-reported bloating severity assessed by study questionnaire.
Measured: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Flatulence Severity
Change in participant-reported flatulence severity assessed by study questionnaire.
Measured: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Heartburn Severity
Change in participant-reported heartburn severity assessed by study questionnaire.
Measured: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Digestive Comfort
Change in participant-reported digestive comfort assessed by study questionnaire.
Measured: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Skin Health
Change in participant-reported skin health assessed by study questionnaire.
Measured: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jun 2026
- Study start5 Jun 2025
- Primary completion15 Jan 2026
- Study completion15 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Metabolic HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- Biocol Labs
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07673432
- Sponsor's protocol ID
- #20758
- Status last verified
- Jun 2026
- First submitted
- 23 Jun 2026
- Last updated
- 29 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Clinical Trial to Evaluate the Effects of a Plant-Based Liquid Supplement on Metabolic Health and Overall Well-Being
- ClinicalTrials.gov ID
- NCT07673432
- Acronym / sponsor ID
- #20758
- Conditions
- Metabolic Health, Elevated Liver Enzymes, Digestive Symptoms
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- Biocol LabsIndustry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Study start
- 5 Jun 2025 (actual)
- Primary completion
- 15 Jan 2026 (actual)
- Study completion
- 15 Jan 2026 (actual)
- First posted
- 29 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This single-arm clinical trial will evaluate the effects of a plant-based liquid supplement on metabolic health, digestive health, skin health, and overall well-being. Twenty participants aged 40 to 60 years with elevated alanine transaminase (ALT) or aspartate transaminase (AST) levels will use the supplement daily for 90 days. Participants will complete questionnaires, provide body composition and waist circumference measurements, submit photographs, and undergo blood testing throughout the study. Outcomes include changes in metabolic biomarkers, body composition, digestive symptoms, skin health, and overall well-being.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Plant-Based Liquid Supplement | Experimental | Dietary Supplement: Plant-Based Liquid SupplementParticipants will consume one ampule of the study product diluted in approximately 8 ounces of water before the first meal of the day throughout the study period. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (12 listed)
- Age 40 to 60 years
- Elevated ALT or AST identified during prescreening blood testing
- Currently experiencing at least two of the following:
- Stomach discomfort, Constipation, Diarrhea, Heartburn, Bloating, Gas, Abdominal pain, Skin redness or pimples, Sugar cravings
- Willing to comply with study requirements
Key exclusion criteria (9 listed)
- Severe digestive disorders including acid reflux, IBS, IBD, Crohn's disease, or gastrointestinal tract surgeries
- Liver disease
- Known allergy or hypersensitivity to study product ingredients Chronic conditions that would interfere with study participation, including oncological or psychiatric disorders
- Known severe allergic reactions
- Pregnant, breastfeeding, or attempting to conceive
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Plant-Based Liquid SupplementA liquid dietary supplement containing choline bitartrate, zinc sulfate, manganese sulfate, artichoke leaf extract, fennel extract, rosemary leaf extract, L-arginine monohydrochloride, inositol, bromelain, papain, sorbitol, glycerin, artificial flavour, and potassium sorbate. | Dietary supplement | Plant-Based Liquid Supplement |
Primary outcome
Change in Body Weight
Time frame: Baseline, Day 30, Day 60, and Day 90.
Change in body weight measured using a Withings smart scale.
Change in Waist Circumference
Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in waist circumference measured using a tape measure and recorded in centimeters.
Change in Body Fat Mass
Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in body fat mass measured using a Withings smart scale.
Change in Lean Body Mass
Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in lean body mass measured using a Withings smart scale.
Change in Visceral Fat Index
Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.
Change in visceral fat index measured using a Withings smart scale.
Change in Alanine Aminotransferase (ALT)
Time frame: Baseline, Day 30, Day 60, and Day 90.
Change in serum alanine aminotransferase concentration measured by hepatic function panel.
Change in Aspartate Aminotransferase (AST)
Time frame: Baseline, Day 30, Day 60, and Day 90
Change in serum aspartate aminotransferase concentration measured by hepatic function panel.
Change in Alkaline Phosphatase (ALP)
Time frame: Baseline, Day 30, Day 60, and Day 90.
Change in serum alkaline phosphatase concentration measured by hepatic function panel.
Change in Total Bilirubin
Time frame: Baseline, Day 30, Day 60, and Day 90.
Change in serum total bilirubin concentration measured by hepatic function panel.
Change in Total Cholesterol
Time frame: Baseline, Day 30, Day 60, and Day 90.
Change in serum total cholesterol concentration measured by lipid panel.
5 secondary outcomes
Change in Participant-Reported Bloating Severity
Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Flatulence Severity
Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Heartburn Severity
Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Digestive Comfort
Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Change in Participant-Reported Skin Health
Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Plant-Based Liquid Supplement in people with Metabolic Health and Elevated Liver Enzymes, run by Biocol Labs at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 12 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Body Weight (time frame: Baseline, Day 30, Day 60, and Day 90.). The study lists 10 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jun 2026.