Bone Loss, AlveolarNCT07664605
Outcomes of Ridge Splitting Versus Sausage Technique
A study testing Ridge split in people with Bone Loss, Alveolar, run by Beni-Suef University at 1 site in Egypt.
Trial summary
The current study aims to increase the width of the alveolar bone in defective mandibular ridge with simultaneous implant placement and enhance the implant stability Read more about this study
- Who is it for?
- Ages 20 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Bone Loss, Alveolar
- What is being tested?
- Ridge split
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2026to 1 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients with deficient bone volume between (2 : 3.5 ) mm
- Patients must have installed functional implant for no less than 3 months- enough time to allow for bone augmentation changes.
- Patients with no defect in the gingival tissues.
- Patients with un-remarkable medical compromising conditions
- Patients with good oral hygiene at time of the examination
Who cannot join
- Patients with compromising medical condition.
- Patients with severe bone resorption.
- Patients with D1 or D2 bone.
- Bone height <10mm
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Beni-Suef University
Cairo
ahmed alghandour, phd, 002012457435 ext. 002, dr.ahmnagi@yahoo.com
About this study
Official title: Outcomes Of Ridge Splitting Versus Sausage Technique With Simultaneous Implant Placement For Augmenting Mandibular Horizontal Bone Defects.
The current study aims to increase the width of the alveolar bone in defective mandibular ridge with simultaneous implant placement and enhance the implant stability
Read the detailed description
Several bone augmentation approaches address horizontal bone resorption to achieve successful implantation including bone block grafting, guided bone regeneration (GBR), sinus augmentation and alveolar ridge split , However, bone block grafting had disadvantages like donor site morbidity and longer treatment time,GBR had the risk of infection due to exposure membrane and collapse of the regeneration membrane (1)These drawbacks may eventually lead to implant failure Alternatively, the Alveolar ridge splitting technique may solve some barriers and create proper dimensions for delayed or immediate implantation in both maxillary and mandible.(2) The alveolar ridge splitting technique was introduced by Simion in 1992 as a successful bone grafting technique to augment the horizontally deficient alveolar ridge with immediate implant placement. (3)The main disadvantage of the conventional ridge splitting technique is the high risk of bad split, fractures or even fenestrations of the buccal cortical plate of bone during separation with massive crestal bone loss surrounding the implants.(4)Therefore, a lot of clinical trials were introduced using minimally invasive protocols dealing with such complications for example, the usage of piezoelectric surgery or using surgical guides.(5)
In the past, onlay grafts of bone harvested from the hip, maxillary tuberosity, symphysis of the chin, or external oblique ridge have all been used with success in reconstruction of atrophic ridges,onlay grafts often require a healing period of 6 months to a year before dental implants can be placed, and the onlay graft sometimes fails to fuse to the augmented site. (6)The segmental ridge-split procedure provides a quicker method where in an atrophic ridge can be predictably expanded and grafted with bone allograft, eliminating the need for a second surgical site.(7) Using of piezoelectric alveolar ridge splitting (ARS) with simultaneous implant placement will enhance implant stability in comparison with conventional motorized surgical disc and bur .(8) Piezosurgery enhanced implant stability but didn,t mitigate the bone loss associated with ARS or increase amount of ridge width gain.(9)
The piezosurgery can be a safer option in maintaining the vitality of bone and piezoelectric implant site drilling protocol seemed to be a reliable and repeatable technique. (10) Preparation of the implant bed with the aid of piezoelectric inserts showed improved implant stability with a 100% success rate .(11) Extensive alveolar bone augmentation using sausage technique achieved significant horizontal or vertical bone height or width increase, and the retention rate after 6 months was also high,In addition, surgery in the maxillary region showed a more successful bone augmentation than in the mandible, with a higher maintenance rate. (12)The concept of GBR uses graft materials as a scaffold to preserve the created space and a non-resorbable or resorbable membrane to exclude the growth of epithelium and connective tissue cells inward the defect. (13) Urban and colleagues proposed an improved technique to stabilize the graft material to the crest by modifying the collagen membrane fixation method and the original sausage technique combines autograft chips with an organic bovine bone mineral (ABBM) particles to provide the graft mixture with osteogenic properties.(14) Briefly, the technique is similar to conventional GBR in that the membrane is fixed with pins, However, the graft material is filled inside the fixed membrane in a sufficient quantity to show a balloon effect and to push the graft material in the crestal direction to create tension on the membrane ,In this technique, two types of collagen membranes can be used: a crosslinked synthetic collagen membrane or a native collagen membrane.(15)
- Conditions
- Bone Loss, Alveolar
- Being tested
- Ridge split
- Medical subject headings
- Alveolar Bone Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ridge splitProcedure or surgery
The alveolar ridge splitting technique was introduced by Simion in 1992 as a successful bone grafting technique to augment the horizontally deficient alveolar ridge with immediate implant placement
| Study group | Role | What they receive |
|---|---|---|
| Ridge split | Active comparator | Not described Receives: Procedure: Ridge split |
| Sausage techinque | Active comparator | Not described Receives: Procedure: Ridge split |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of bone width
Cone beam CT used to asses bone density
Measured: (4-6) months
Implant primary stability
Osstel device used to asses the stability from 1 to 100
Measured: (4-6 )months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jun 2026
- Study start1 Jun 2026 (estimated)
- Primary completion1 Nov 2026 (estimated)
- Study completion1 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Bone Loss, AlveolarStudies of the same condition, open and under way.
- More trials run by Beni-Suef UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Beni-Suef University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Nagi Alghandour, Beni-Suef University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07664605
- Sponsor's protocol ID
- 25230
- Status last verified
- Jun 2026
- First submitted
- 22 May 2026
- Last updated
- 24 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Lin Y, Li G, Xu T, Zhou X, Luo F. The efficacy of alveolar ridge split on implants: a systematic review and meta-analysis. BMC Oral Health. 2023 Nov 20;23(1):894. doi: 10.1186/s12903-023-03643-2.
PubMed 37986181Hamzah B, Mounir R, Ali S, Mounir M. Maxillary horizontal alveolar ridge augmentation using computer guided ridge splitting with simultaneous implant placement versus conventional technique: A randomized clinical trial. Clin Implant Dent Relat Res. 2021 Aug;23(4):555-561. doi: 10.1111/cid.13015. Epub 2021 Jun 8.
PubMed 34105231Arakji H, Osman E, Aboelsaad N, Shokry M. Evaluation of implant site preparation with piezosurgery versus conventional drills in terms of operation time, implant stability and bone density (randomized controlled clinical trial- split mouth design). BMC Oral Health. 2022 Dec 3;22(1):567. doi: 10.1186/s12903-022-02613-4.
PubMed 36463145
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Outcomes Of Ridge Splitting Versus Sausage Technique With Simultaneous Implant Placement For Augmenting Mandibular Horizontal Bone Defects.
- ClinicalTrials.gov ID
- NCT07664605
- Acronym / sponsor ID
- 25230
- Conditions
- Bone Loss, Alveolar
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Beni-Suef UniversityUniversity, hospital or other
- Study start
- 1 Jun 2026 (estimated)
- Primary completion
- 1 Nov 2026 (estimated)
- Study completion
- 1 Dec 2026 (estimated)
- First posted
- 24 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current study aims to increase the width of the alveolar bone in defective mandibular ridge with simultaneous implant placement and enhance the implant stability
Detailed description
Several bone augmentation approaches address horizontal bone resorption to achieve successful implantation including bone block grafting, guided bone regeneration (GBR), sinus augmentation and alveolar ridge split , However, bone block grafting had disadvantages like donor site morbidity and longer treatment time,GBR had the risk of infection due to exposure membrane and collapse of the regeneration membrane (1)These drawbacks may eventually lead to implant failure Alternatively, the Alveolar ridge splitting technique may solve some barriers and create proper dimensions for delayed or immediate implantation in both maxillary and mandible.(2) The alveolar ridge splitting technique was introduced by Simion in 1992 as a successful bone grafting technique to augment the horizontally deficient alveolar ridge with immediate implant placement. (3)The main disadvantage of the conventional ridge splitting technique is the high risk of bad split, fractures or even fenestrations of the buccal cortical plate of bone during separation with massive crestal bone loss surrounding the implants.(4)Therefore, a lot of clinical trials were introduced using minimally invasive protocols dealing with such complications for example, the usage of piezoelectric surgery or using surgical guides.(5)
In the past, onlay grafts of bone harvested from the hip, maxillary tuberosity, symphysis of the chin, or external oblique ridge have all been used with success in reconstruction of atrophic ridges,onlay grafts often require a healing period of 6 months to a year before dental implants can be placed, and the onlay graft sometimes fails to fuse to the augmented site. (6)The segmental ridge-split procedure provides a quicker method where in an atrophic ridge can be predictably expanded and grafted with bone allograft, eliminating the need for a second surgical site.(7) Using of piezoelectric alveolar ridge splitting (ARS) with simultaneous implant placement will enhance implant stability in comparison with conventional motorized surgical disc and bur .(8) Piezosurgery enhanced implant stability but didn,t mitigate the bone loss associated with ARS or increase amount of ridge width gain.(9)
The piezosurgery can be a safer option in maintaining the vitality of bone and piezoelectric implant site drilling protocol seemed to be a reliable and repeatable technique. (10) Preparation of the implant bed with the aid of piezoelectric inserts showed improved implant stability with a 100% success rate .(11) Extensive alveolar bone augmentation using sausage technique achieved significant horizontal or vertical bone height or width increase, and the retention rate after 6 months was also high,In addition, surgery in the maxillary region showed a more successful bone augmentation than in the mandible, with a higher maintenance rate. (12)The concept of GBR uses graft materials as a scaffold to preserve the created space and a non-resorbable or resorbable membrane to exclude the growth of epithelium and connective tissue cells inward the defect. (13) Urban and colleagues proposed an improved technique to stabilize the graft material to the crest by modifying the collagen membrane fixation method and the original sausage technique combines autograft chips with an organic bovine bone mineral (ABBM) particles to provide the graft mixture with osteogenic properties.(14) Briefly, the technique is similar to conventional GBR in that the membrane is fixed with pins, However, the graft material is filled inside the fixed membrane in a sufficient quantity to show a balloon effect and to push the graft material in the crestal direction to create tension on the membrane ,In this technique, two types of collagen membranes can be used: a crosslinked synthetic collagen membrane or a native collagen membrane.(15)
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ridge split | Active comparator | Procedure: Ridge split |
| Sausage techinque | Active comparator | Procedure: Ridge split |
Who may qualify
- Ages
- 20 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Patients with deficient bone volume between (2 : 3.5 ) mm
- Patients must have installed functional implant for no less than 3 months- enough time to allow for bone augmentation changes.
- Patients with no defect in the gingival tissues.
- Patients with un-remarkable medical compromising conditions
- Patients with good oral hygiene at time of the examination
Key exclusion criteria (4 listed)
- Patients with compromising medical condition.
- Patients with severe bone resorption.
- Patients with D1 or D2 bone.
- Bone height <10mm
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ridge splitThe alveolar ridge splitting technique was introduced by Simion in 1992 as a successful bone grafting technique to augment the horizontally deficient alveolar ridge with immediate implant placement | Procedure or surgery | Ridge split, Sausage techinque |
Primary outcome
Evaluation of bone width
Time frame: (4-6) months
Cone beam CT used to asses bone density
Implant primary stability
Time frame: (4-6 )months
Osstel device used to asses the stability from 1 to 100
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2026.
- Background: PubMed 37986181Lin Y, Li G, Xu T, Zhou X, Luo F. The efficacy of alveolar ridge split on implants: a systematic review and meta-analysis. BMC Oral Health. 2023 Nov 20;23(1):894. doi: 10.1186/s12903-023-03643-2.
- Background: PubMed 34105231Hamzah B, Mounir R, Ali S, Mounir M. Maxillary horizontal alveolar ridge augmentation using computer guided ridge splitting with simultaneous implant placement versus conventional technique: A randomized clinical trial. Clin Implant Dent Relat Res. 2021 Aug;23(4):555-561. doi: 10.1111/cid.13015. Epub 2021 Jun 8.
- Background: PubMed 36463145Arakji H, Osman E, Aboelsaad N, Shokry M. Evaluation of implant site preparation with piezosurgery versus conventional drills in terms of operation time, implant stability and bone density (randomized controlled clinical trial- split mouth design). BMC Oral Health. 2022 Dec 3;22(1):567. doi: 10.1186/s12903-022-02613-4.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ridge split in people with Bone Loss, Alveolar, run by Beni-Suef University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact ahmed alghandour, phd (01224567435 ext. 002, ahmed.nagi@dent.bsu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of bone width (time frame: (4-6) months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07664605, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2026.