Vestibular DisorderNCT07575074
OKT With Gaze and Postural Stabilization on Vertigo, MS and QOL in VBH
A study testing Group A Habituation exercises and Group B Optokinetic training protocol in people with Vestibular Disorder, run by Riphah International University at 1 site in Pakistan.
Trial summary
The objective of this study will evaluate the effects of optokinetic training combined with postural stabilization and gaze stability exercises on motion sickness, balance, gaze stability, and quality of life in individuals with vestibular hypofunction. Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Vestibular Disorder
- What is being tested?
- Group A Habituation exercises and Group B Optokinetic training protocol
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 15 May 2026to 14 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- • Male and female patients age 20 and 40 years
- Passengers who have motion sickness during travelling
- Patients of vestibular migraine who experience motion sickness
- Participants experiencing vertigo, dizziness or imbalance related to vestibular hypofunction over the past three months
Who cannot join
- • Patients who have seasickness and simulator sickness excluded.
- Patients having vestibular disease and chronic neurological disease.
- Participants who have completed formal vestibular rehabilitation in last 6 months excluded
- Patients with severe visual impairments and orthopedic conditions excluded.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Ittefaq Hospital Lahore
Lahore, Punjab Province, 54500
Javeria Ghazal, MSNMPT, +923335154664, javeria.ghazal@riphah.edu.pk
Asad Shahzad Mir, MsNMPT
About this study
Official title: Effects of Optokinetic Training With Gaze and Postural Stabilization on Vertigo, Motion Sickness and Quality of Life in Vestibular Hypofunction
The objective of this study will evaluate the effects of optokinetic training combined with postural stabilization and gaze stability exercises on motion sickness, balance, gaze stability, and quality of life in individuals with vestibular hypofunction.
Read the detailed description
A randomized clinical trial will be conducted with 32 participants assigned to two groups: Group A (breathing and aerobic exercises) and Group B (optokinetic training combined with postural stabilization and gaze stability exercises). Data will be collected using the Motion Sickness Susceptibility Questionnaire (MSSQ), Berg Balance Scale (BBS), Dynamic Visual Acuity Test for Gaze Stability, and Head Impulse Test. Statistical analysis will be performed by SPSS.
- Conditions
- Vestibular Disorder
- Being tested
- Group A Habituation exercises, Group B Optokinetic training protocol
- Keywords
- Balance, gaze stability, motion sickness, optokinetic training
- Medical subject headings
- Vestibular Diseases, Motion Sickness
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group A Habituation exercisesOther
Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness (38). Each session, lasting approximately 20-25 minutes, involved exercises conducted for 20 minutes per day, five times a week. Each session, lasting approximately 30-45 minutes, included low-intensity breathing exercises aimed at promoting relaxation and moderate-intensity aerobic activities, such as walking or cycling, at 50-60% of the participant's maximum heart rate.
Group B Optokinetic training protocolOther
10-minute warm-up, followed by 20-25 minutes of moderate-intensity optokinetic exercises (viewing controlled moving visual patterns), postural exercises involving controlled head and body movements to engage the vestibular system, and gaze stability exercises, which require focusing on a stationary target during head movements to improve the vestibulo-ocular reflex. The session concluded with a 10-15-minute cool-down to aid relaxation. These sessions continued for 12 weeks
| Study group | Role | What they receive |
|---|---|---|
| Group A Habituation exercises | Experimental | Group A performed a regime of Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness Receives: Other: Group A Habituation exercises |
| Group B Optokinetic training protocol | Experimental | Group B underwent a structured optokinetic training protocol combined with postural stabilization and gaze stability exercises, targeting both gaze and postural control systems. Receives: Other: Group B Optokinetic training protocol |
What is being measured
The primary outcome is the main question the study is designed to answer.
Motion sickness susceptibility questionnaire
The Motion Sickness Susceptibility Questionnaire (MSSQ) is a widely used tool that assesses an individual's predisposition to motion sickness in various environments, such as vehicles, amusement rides, and virtual reality.
Measured: 8th week
Berg balance scale
The Berg Balance Scale (BBS) is a reliable clinical tool used to assess balance in individuals, particularly older adults and those with balance impairments. It includes 14 tasks each scored from 0 (cannot perform) to 4 (performs independently). The BBS has a maximum score of 56, and most of the patients show a low fall risk of 41 to 56 scores, medium risk of 21 to 40 scores, and a high risk of 0 to 20 scores.
Measured: 8th week
Dynamic visual acuity test for gaze stability
The Dynamic Visual Acuity (DVA) Test is a widely used clinical test to assess gaze stability, particularly in individuals with vestibular dysfunction. It evaluates a person's ability to maintain clear vision during head movements, which requires stable gaze control. The test involves reading porotype letters or symbols displayed on a screen, first in a stationary position and then while moving the head horizontally and vertically at a standardized speed (usually around 2 Hz)
Measured: 8th week
Head impulse test
The Head Impulse Test (HIT) is a diagnostic tool used to evaluate the function of the vestibulo-ocular reflex (VOR), essential for maintaining gaze stability during rapid head movements. In this test, a clinician rapidly and unpredictably turns the patient's head to the left or right while the patient focuses on a stationary target, typically the clinician's nose. For a healthy VOR, the eyes should remain fixed on the target despite the head movement
Measured: 8th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 May 2026
- Study start15 May 2026 (estimated)
- Primary completion15 Aug 2026 (estimated)
- Study completion14 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Vestibular DisorderStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Javeria Ghazal, MSNMPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07575074
- Sponsor's protocol ID
- REC/RCR & AHS/24/02100
- Status last verified
- May 2026
- First submitted
- 22 Feb 2026
- Last updated
- 8 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Optokinetic Training With Gaze and Postural Stabilization on Vertigo, Motion Sickness and Quality of Life in Vestibular Hypofunction
- ClinicalTrials.gov ID
- NCT07575074
- Acronym / sponsor ID
- REC/RCR & AHS/24/02100
- Conditions
- Vestibular Disorder
- Keywords
- Balance, gaze stability, motion sickness, optokinetic training
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 15 May 2026 (estimated)
- Primary completion
- 15 Aug 2026 (estimated)
- Study completion
- 14 Sep 2026 (estimated)
- First posted
- 8 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of this study will evaluate the effects of optokinetic training combined with postural stabilization and gaze stability exercises on motion sickness, balance, gaze stability, and quality of life in individuals with vestibular hypofunction.
Detailed description
A randomized clinical trial will be conducted with 32 participants assigned to two groups: Group A (breathing and aerobic exercises) and Group B (optokinetic training combined with postural stabilization and gaze stability exercises). Data will be collected using the Motion Sickness Susceptibility Questionnaire (MSSQ), Berg Balance Scale (BBS), Dynamic Visual Acuity Test for Gaze Stability, and Head Impulse Test. Statistical analysis will be performed by SPSS.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A Habituation exercises | Experimental | Other: Group A Habituation exercisesGroup A performed a regime of Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness |
| Group B Optokinetic training protocol | Experimental | Other: Group B Optokinetic training protocolGroup B underwent a structured optokinetic training protocol combined with postural stabilization and gaze stability exercises, targeting both gaze and postural control systems. |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- • Male and female patients age 20 and 40 years
Key exclusion criteria (4 listed)
- • Patients who have seasickness and simulator sickness excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group A Habituation exercisesHabituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness (38). Each session, lasting approximately 20-25 minutes, involved exercises conducted for 20 minutes per day, five times a week. Each session, lasting approximately 30-45 minutes, included low-intensity breathing exercises aimed at promoting relaxation and moderate-intensity aerobic activities, such as walking or cycling, at 50-60% of the participant's maximum heart rate. | Other | Group A Habituation exercises |
| Group B Optokinetic training protocol10-minute warm-up, followed by 20-25 minutes of moderate-intensity optokinetic exercises (viewing controlled moving visual patterns), postural exercises involving controlled head and body movements to engage the vestibular system, and gaze stability exercises, which require focusing on a stationary target during head movements to improve the vestibulo-ocular reflex. The session concluded with a 10-15-minute cool-down to aid relaxation. These sessions continued for 12 weeks | Other | Group B Optokinetic training protocol |
Primary outcome
Motion sickness susceptibility questionnaire
Time frame: 8th week
The Motion Sickness Susceptibility Questionnaire (MSSQ) is a widely used tool that assesses an individual's predisposition to motion sickness in various environments, such as vehicles, amusement rides, and virtual reality.
Berg balance scale
Time frame: 8th week
The Berg Balance Scale (BBS) is a reliable clinical tool used to assess balance in individuals, particularly older adults and those with balance impairments. It includes 14 tasks each scored from 0 (cannot perform) to 4 (performs independently). The BBS has a maximum score of 56, and most of the patients show a low fall risk of 41 to 56 scores, medium risk of 21 to 40 scores, and a high risk of 0 to 20 scores.
Dynamic visual acuity test for gaze stability
Time frame: 8th week
The Dynamic Visual Acuity (DVA) Test is a widely used clinical test to assess gaze stability, particularly in individuals with vestibular dysfunction. It evaluates a person's ability to maintain clear vision during head movements, which requires stable gaze control. The test involves reading porotype letters or symbols displayed on a screen, first in a stationary position and then while moving the head horizontally and vertically at a standardized speed (usually around 2 Hz)
Head impulse test
Time frame: 8th week
The Head Impulse Test (HIT) is a diagnostic tool used to evaluate the function of the vestibulo-ocular reflex (VOR), essential for maintaining gaze stability during rapid head movements. In this test, a clinician rapidly and unpredictably turns the patient's head to the left or right while the patient focuses on a stationary target, typically the clinician's nose. For a healthy VOR, the eyes should remain fixed on the target despite the head movement
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 May 2026.
- Individual participant dataSharing planned: No
Related trials for Vestibular Disorder
RecruitingPhase 3
Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients
Vestibular Schwannoma, Facial Nerve Paralysis
Not yet recruiting
Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis
Knee Osteoarthritis, Visual Rehabilitation
Recruiting
Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma
Vestibular Schwannoma, Unilateral Vestibular Deficit
RecruitingObservational study
Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer
Ototoxic Hearing Loss, Ototoxicity, Drug-Induced
RecruitingObservational study
Natural History Study of Patients With Neurofibromatosis Type 2
Neurofibromatosis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Javeria Ghazal, MSNMPT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group A Habituation exercises and Group B Optokinetic training protocol in people with Vestibular Disorder, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Muneeb Khan, PhD (923367993611, muneeb.khan@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Motion sickness susceptibility questionnaire (time frame: 8th week). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 May 2026.