Functional Neurological DisorderFONDANCT07538414
Investigation of Patients Presenting With Acute Functional Neurological Symptoms
An observational study of Functional Neurological Disorder, run by University Hospital, Basel, Switzerland at 1 site in Switzerland.
Trial summary
Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases Read more about this study
- Who is it for?
- Ages 16 years and older
- Conditions the study is for
- Functional Neurological Disorder
- What is being tested?
- collection of patient data
- How many people
- 1,000 participants
- Where
- 1 siteSwitzerland
- Study dates
- 30 Mar 2026to Dec 2050
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Patients presenting with acute symptoms
Who may be able to join
- Patients older than 16 years old presenting as an emergency case to the University Hospital Basel between 1 January 2012 and 31 March 2026
- with acute neurological symptoms requiring immediate neurological work-up (e.g, acute motor or sensory disturbance, acute speech disorder, acute vestibular disorder, acute cognitive disorder, acute consciousness disorder, acute seizure disorder)
- and a documented diagnostic evaluation during hospitalization.
Who cannot join
- Documented refusal for further use of health related data for research purposes
- Insufficient documentation to determine diagnosis or clinical course
- Incomplete or inconsistent datasets compromising valid endpoint determination
- Younger than 16 years
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Switzerland1 site, 1 recruiting
- Recruiting
University Hospital Basel
Basel, 4031
Urs Fisch, MD PhD, +41 61 265 25 25, urs.fisch@usb.ch
About this study
Official title: Functional Neurological Disorders in Acute Hospital Care
Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases
- Conditions
- Functional Neurological Disorder
- Being tested
- collection of patient data
- Medical subject headings
- Conversion Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
collection of patient dataOther
collection of patient data
What is being measured
The primary outcome is the main question the study is designed to answer.
Frequency of FND
The primary endpoint is the proportion of patients presenting with acute neurological symptoms who receive a diagnosis or likely differential diagnosis of Functional Neurological Disorder (FND) during their index hospital admission.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary outcomes (8)
Secondary Outcomes
Diagnostic Process Measures (%): Referral patterns and evaluation of alternative or concurrent neurological diagnoses.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Diagnostic Resource Utilization (%): Clinical examination findings, neuroimaging, neurophysiological testing, and laboratory investigations.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Healthcare Utilization and Outcomes (%): Discharge destination, readmission, outpatient follow-up, and in-hospital mortality.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Quality of Care Associations (%) Demographic and clinical variables associated with diagnostic performance and healthcare utilization.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Comparative Analyses: FND vs Non-FND (%): Differences in diagnostics, resource utilization, escalation of care, and short-term outcomes.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Subtype Analyses (%): Differences across FND subtypes in presentation, diagnostics, management, and outcomes.
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time to Definitive Diagnosis (days)
Measured: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Length of Hospital Stay (days)
Measured: At hospital discharge (index admission), up to 30 days from presentation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Apr 2026
- Study start30 Mar 2026
- Primary completionDec 2050 (estimated)
- Study completionDec 2050 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Functional Neurological DisorderStudies of the same condition, open and under way.
- More trials run by University Hospital, Basel, SwitzerlandThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Basel, Switzerland
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Urs Fisch, University Hospital, Basel, Switzerland
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07538414
- Sponsor's protocol ID
- 2026-00643
- Acronym
- FONDA
- Status last verified
- Apr 2026
- First submitted
- 30 Mar 2026
- Last updated
- 20 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Functional Neurological Disorders in Acute Hospital Care
- ClinicalTrials.gov ID
- NCT07538414
- Acronym / sponsor ID
- FONDA / 2026-00643
- Conditions
- Functional Neurological Disorder
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- University Hospital, Basel, SwitzerlandUniversity, hospital or other
- Study start
- 30 Mar 2026 (actual)
- Primary completion
- Dec 2050 (estimated)
- Study completion
- Dec 2050 (estimated)
- First posted
- 20 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 16 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients presenting with acute symptoms
Key inclusion criteria (3 listed)
- Patients older than 16 years old presenting as an emergency case to the University Hospital Basel between 1 January 2012 and 31 March 2026
- with acute neurological symptoms requiring immediate neurological work-up (e.g, acute motor or sensory disturbance, acute speech disorder, acute vestibular disorder, acute cognitive disorder, acute consciousness disorder, acute seizure disorder)
- and a documented diagnostic evaluation during hospitalization.
Key exclusion criteria (4 listed)
- Documented refusal for further use of health related data for research purposes
- Insufficient documentation to determine diagnosis or clinical course
- Incomplete or inconsistent datasets compromising valid endpoint determination
- Younger than 16 years
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| collection of patient datacollection of patient data | Other | – |
Primary outcome
Frequency of FND
Time frame: At hospital discharge (index admission), up to 30 days from presentation
The primary endpoint is the proportion of patients presenting with acute neurological symptoms who receive a diagnosis or likely differential diagnosis of Functional Neurological Disorder (FND) during their index hospital admission.
8 secondary outcomes
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Functional Neurological Disorder, run by University Hospital, Basel, Switzerland at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 20 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Urs Fisch, MD PhD (+41 61 265 2525, urs.fisch@usb.ch), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Frequency of FND (time frame: At hospital discharge (index admission), up to 30 days from presentation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Apr 2026.