Knee OARCTNCT07478861
Whole-body Vibration Training on the Elderly With Combined Bilateral Knee Osteoarthritis
A study testing Whole-body vibration training in people with Knee OA and Sarcopenic Obesity, run by Beni-Suef University at 1 site in Egypt.
Trial summary
This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance [gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with… Read more about this study
- Who is it for?
- Ages 60 to 75 years
- Conditions the study is for
- Knee OA, Sarcopenic Obesity, Whole Body Vibration
- What is being tested?
- Whole-body vibration training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Nov 2026to 15 Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients with KOA were graded based on the Kellgren-Lawrence grading criteria (K-L grading)
- only grades 3 and 4 will be included in this study
- Sarcopenia obesity based on with SMI with SMI < 7 kg/m2
- PBF ≥ 30% into the SO group
- BMI ≥ 28%, or waist circumference ≥ 85 cm in men and ≥ 80 cm in women
- able to communicate
Who cannot join
- Inability to walk
- Knee joint underwent drug treatment or intra-articular injection
- Uncontrollable angina pectoris induced by exercise
- Uncontrolled hypertension, acute or chronic renal failure, or dyspnea in the resting state
- Neurological or respiratory conditions or injuries (ie, dementia, Alzheimer's disease, multiple sclerosis, chronic obstructive pulmonary disease), rheumatoid arthritis and clinical depression.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Impact of Whole-body Vibration Training (WBVT) on the Elderly With Combined Bilateral Knee Osteoarthritis (KOA) and Sarcopenic Obesity
This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance [gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with knee OA and sarcopenic obesity in a group of Men compared to group of females.
Read the detailed description
Both groups received the intervention 3 times a week for 12 weeks. WBVT group. Each intervention lasted 30 min, which included 5 min of warm-up, 20 min of vibration training, and 5 min of relaxation.
- Conditions
- Knee OA, Sarcopenic Obesity, Whole Body Vibration
- Being tested
- Whole-body vibration training
- Keywords
- knee osteoarthritis, elderly patients, sarcopenic obesity, whole body vibration training
- Medical subject headings
- Osteoarthritis, Knee
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Whole-body vibration trainingOther
Whole-body vibration therapy stimulates muscle contraction. It can increase muscle function to a level like that of classical resistance training, but with the advantage of being more convenient and safer
| Study group | Role | What they receive |
|---|---|---|
| Elderly male patients with knee osteoarthritis | Experimental | Elderly male patients with knee osteoarthritis associated with sarcopenic obesity Receives: Other: Whole-body vibration training |
| Elderly female patients with knee osteoarthritis | Active comparator | Elderly female patients with knee osteoarthritis associated with sacropenic obesity Receives: Other: Whole-body vibration training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Physical performance
These are standardized tests used to assess lower limb strength, mobility, and overall functional ability in elderly patients it includes: 1. Gait speed (it is the rate a person can tolerate walking measured in meter per seconds (ask the person to walk at their usual comfortable pace for 10 meters; and record how many seconds it takes to complete this distance and evaluate the recorded time before and after the treatment); 2. 5-time chair stand test; t evaluates how quickly a participant can perform 5 successive sit-to-stand without using their arms (it evaluate the time taken to complete 5 repetitions, a. ≤ 12 seconds is considered normal physical performance, b. > 15 seconds may indicate lower extremity weakness, mobility limitations, or increased fall risk, c. Unable to complete indicates significant functional impairment). All measurements will be carried out before the treatment and after the end of the treatment.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Mar 2026
- Study start15 Nov 2026 (estimated)
- Primary completion15 Feb 2027 (estimated)
- Study completion15 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee OAStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance \[gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with knee OA and sarcopenic obesity in a group of Men compared to group of females.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Beni-Suef University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mariam Abdel Rahman, Beni-Suef University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07478861
- Sponsor's protocol ID
- Faculty of Physical Therapy
- Other IDs
- Mariam Abdel Rahman
- Acronym
- RCT
- Status last verified
- Jun 2026
- First submitted
- 3 Mar 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Whole-body Vibration Training (WBVT) on the Elderly With Combined Bilateral Knee Osteoarthritis (KOA) and Sarcopenic Obesity
- ClinicalTrials.gov ID
- NCT07478861
- Acronym / sponsor ID
- RCT / Faculty of Physical Therapy
- Conditions
- Knee OA, Sarcopenic Obesity, Whole Body Vibration
- Keywords
- knee osteoarthritis, elderly patients, sarcopenic obesity, whole body vibration training
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Beni-Suef UniversityUniversity, hospital or other
- Study start
- 15 Nov 2026 (estimated)
- Primary completion
- 15 Feb 2027 (estimated)
- Study completion
- 15 Apr 2027 (estimated)
- First posted
- 18 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance [gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with knee OA and sarcopenic obesity in a group of Men compared to group of females.
Detailed description
Both groups received the intervention 3 times a week for 12 weeks. WBVT group. Each intervention lasted 30 min, which included 5 min of warm-up, 20 min of vibration training, and 5 min of relaxation.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance [gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with knee OA and sarcopenic obesity in a group of Men compared to group of females.
| Arm | Type | Receives |
|---|---|---|
| Elderly male patients with knee osteoarthritis | Experimental | Other: Whole-body vibration trainingElderly male patients with knee osteoarthritis associated with sarcopenic obesity |
| Elderly female patients with knee osteoarthritis | Active comparator | Other: Whole-body vibration trainingElderly female patients with knee osteoarthritis associated with sacropenic obesity |
Who may qualify
- Ages
- 60 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Patients with KOA were graded based on the Kellgren-Lawrence grading criteria (K-L grading)
- only grades 3 and 4 will be included in this study
- Sarcopenia obesity based on with SMI with SMI < 7 kg/m2
- PBF ≥ 30% into the SO group
- BMI ≥ 28%, or waist circumference ≥ 85 cm in men and ≥ 80 cm in women
Key exclusion criteria (5 listed)
- Inability to walk
- Knee joint underwent drug treatment or intra-articular injection
- Uncontrollable angina pectoris induced by exercise
- Uncontrolled hypertension, acute or chronic renal failure, or dyspnea in the resting state
- Neurological or respiratory conditions or injuries (ie, dementia, Alzheimer's disease, multiple sclerosis, chronic obstructive pulmonary disease), rheumatoid arthritis and clinical depression.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Whole-body vibration trainingWhole-body vibration therapy stimulates muscle contraction. It can increase muscle function to a level like that of classical resistance training, but with the advantage of being more convenient and safer | Other | Elderly female patients with knee osteoarthritis, Elderly male patients with knee osteoarthritis |
Primary outcome
Physical performance
Time frame: 8 weeks
These are standardized tests used to assess lower limb strength, mobility, and overall functional ability in elderly patients it includes: 1. Gait speed (it is the rate a person can tolerate walking measured in meter per seconds (ask the person to walk at their usual comfortable pace for 10 meters; and record how many seconds it takes to complete this distance and evaluate the recorded time before and after the treatment); 2. 5-time chair stand test; t evaluates how quickly a participant can perform 5 successive sit-to-stand without using their arms (it evaluate the time taken to complete 5 repetitions, a. ≤ 12 seconds is considered normal physical performance, b. > 15 seconds may indicate lower extremity weakness, mobility limitations, or increased fall risk, c. Unable to complete indicates significant functional impairment). All measurements will be carried out before the treatment and after the end of the treatment.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Whole-body vibration training in people with Knee OA and Sarcopenic Obesity, run by Beni-Suef University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physical performance (time frame: 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.