Help-Seeking BehaviorNCT07475702
Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)
A study testing Moon and Sun Brothers: A Community Prevention Intervention in people with Help-Seeking Behavior and Pre-exposure Prophylaxis Use, run by San Francisco State University at 2 sites in United States.
Trial summary
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men. The main questions the study aims to answer are: Does the intervention improve sexual risk behaviors? Does the intervention increase self-esteem and social support?… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex
- What is being tested?
- Moon and Sun Brothers: A Community Prevention Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 360 participants
- Where
- 2 sitesUnited States
- Study dates
- 13 Jan 2026to 31 Mar 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Identify as male.
- Latino/x/e
- Report having sex with men only, or both men and women in the last 12 months.
- Speaks, reads/writes in Spanish.
- ≥18 years of age.
- Has access to a computer, laptop, tablet or smart phone device.
- Be willing to participate in the study.
- Be able to provide informed consent.
Who cannot join
- Populations younger than 18 years.
- Individuals who have participated in an Hermanos de Luna y Sol program in either the intervention or control group locations.
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Rita Melendez, PhD contact
United States2 sites, 2 recruiting
- Recruiting
Chicago Queer Latine Collaborative
Chicago, Illinois, 60607
Pedro A Serrano, MPH, DrPH (c), 708-683-9304, pserrano@sfsu.edu
- Recruiting
San Francisco State University
San Francisco, California, 94132
Emma V Sanchez-Vaznaugh, ScD, 415-405-2832, emmav@sfsu.edu
Maria E Acosta, MPH, 415-405-2832, macosta3@sfsu.edu
About this study
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men. The main questions the study aims to answer are:
Does the intervention improve sexual risk behaviors? Does the intervention increase self-esteem and social support? Are self-esteem and social support mediators in the link between the intervention and sexual risk? Researchers will compare information from the intervention versus control participants to answer the above questions.
Read more
Participants in the intervention arm will take part in:
- One day-long (8-hour) group retreat.
- Weekly discussion groups.
- Community events and civic engagement activities.
- Prevention counseling. Participants in the control arm will not be part of any activity.
- Conditions
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
- Being tested
- Moon and Sun Brothers: A Community Prevention Intervention
- Medical subject headings
- Help-Seeking Behavior, Unsafe Sex, Health Risk Behaviors
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Moon and Sun Brothers: A Community Prevention InterventionBehavioural
The is a community-based, group intervention delivered in Spanish, using a quasi-experimental design, to reduce HIV sexual risk among Hispanic immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM).
| Study group | Role | What they receive |
|---|---|---|
| Intervention Community | Other | Over the course of twelve months, study participants will participate in: 1) One day-long (8-hour) group retreat (dosage: 100%); 2) Weekly discussion groups (dosage: minimum of 50% of weekly sessions); 3) Community participation (dosage: minimum of 5 civic engagement activities; 50% of community events); and 4) Prevention counseling sessions (dosage: minimum of 1 session). Intervention participants will take part in all four components. Receives: Behavioral: Moon and Sun Brothers: A Community Prevention Intervention |
| Control Community | No intervention | Participants in the control arm will be unexposed to the intervention components. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Self-reported condomless anal intercourse
Measured: From baseline to end the of intervention, at twelve months.
Secondary outcomes (2)
Self-Esteem
We will assess self-esteem using the 20-item Inner Strength Scale adapted for this study with response options and corresponding scores as follows: never (0), rarely (1), sometimes (2), often (4) and very often (4). The scores ranged from 0 to 80 with higher scores denoting higher degrees of inner strength.
Measured: From enrollment to the end of intervention at 12 months
Social Support
We will assess social support using a 20-item questionnaire developed by Krause, measuring social embeddedness (contact with friends and family) and enacted support from others (which entail emotional, tangible and informational support). These items are scored (coding in parentheses) based on the following responses: never (0), rarely (1), sometimes (2), often (3) and very often (4). The scores range from 0-80, with higher scores denoting a higher degree of social support.
Measured: From enrollment to the end of intervention, at 12 months.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Mar 2026
- Study start13 Jan 2026
- Primary completion31 Mar 2028 (estimated)
- Study completion31 Mar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Help-Seeking BehaviorStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- The study is designed as a quasi-experimental, with a community intervention group and a control group.
- Masking
- None (open label)
- Enrolment
- 360 participants (estimated)
Sponsor and investigators
- Lead sponsor
- San Francisco State University
- Sponsor type
- University, hospital or other
- Collaborators
- Drexel University, Chicago Queer Latine Collaborative, National Institute of Mental Health (NIMH)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07475702
- Sponsor's protocol ID
- 2025-123
- Status last verified
- Jan 2026
- First submitted
- 5 Mar 2026
- Last updated
- 25 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified Individual participant data collected as part of this intervention.
Study at a glance
From the registry record, last updated by the sponsor on 25 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)
- ClinicalTrials.gov ID
- NCT07475702
- Acronym / sponsor ID
- 2025-123
- Conditions
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 360 participants (estimated)
- Lead sponsor
- San Francisco State UniversityUniversity, hospital or other
- Collaborators
- Drexel University, Chicago Queer Latine Collaborative, National Institute of Mental Health (NIMH)
- Study start
- 13 Jan 2026 (actual)
- Primary completion
- 31 Mar 2028 (estimated)
- Study completion
- 31 Mar 2028 (estimated)
- First posted
- 16 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men. The main questions the study aims to answer are:
Does the intervention improve sexual risk behaviors? Does the intervention increase self-esteem and social support? Are self-esteem and social support mediators in the link between the intervention and sexual risk? Researchers will compare information from the intervention versus control participants to answer the above questions.
Participants in the intervention arm will take part in:
- One day-long (8-hour) group retreat.
- Weekly discussion groups.
- Community events and civic engagement activities.
- Prevention counseling. Participants in the control arm will not be part of any activity.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- The study is designed as a quasi-experimental, with a community intervention group and a control group.
| Arm | Type | Receives |
|---|---|---|
| Intervention Community | Other | Behavioral: Moon and Sun Brothers: A Community Prevention InterventionOver the course of twelve months, study participants will participate in: 1) One day-long (8-hour) group retreat (dosage: 100%); 2) Weekly discussion groups (dosage: minimum of 50% of weekly sessions); 3) Community participation (dosage: minimum of 5 civic engagement activities; 50% of community events); and 4) Prevention counseling sessions (dosage: minimum of 1 session). Intervention participants will take part in all four components. |
| Control Community | No intervention | –Participants in the control arm will be unexposed to the intervention components. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Identify as male.
- Latino/x/e
- Report having sex with men only, or both men and women in the last 12 months.
- Speaks, reads/writes in Spanish.
- ≥18 years of age.
Key exclusion criteria (2 listed)
- Populations younger than 18 years.
- Individuals who have participated in an Hermanos de Luna y Sol program in either the intervention or control group locations.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Moon and Sun Brothers: A Community Prevention InterventionThe is a community-based, group intervention delivered in Spanish, using a quasi-experimental design, to reduce HIV sexual risk among Hispanic immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM). | Behavioural | Intervention Community |
Primary outcome
Self-reported condomless anal intercourse
Time frame: From baseline to end the of intervention, at twelve months.
2 secondary outcomes
Self-Esteem
Time frame: From enrollment to the end of intervention at 12 months
Social Support
Time frame: From enrollment to the end of intervention, at 12 months.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Mar 2026.
- Website to promote the studyLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. De-identified Individual participant data collected as part of this intervention.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Rita Melendez, PhD contact
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Moon and Sun Brothers: A Community Prevention Intervention in people with Help-Seeking Behavior and Pre-exposure Prophylaxis Use, run by San Francisco State University at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Emma V Sanchez-Vaznaugh, ScD (415-405-2832, emmav@sfsu.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Self-reported condomless anal intercourse (time frame: From baseline to end the of intervention, at twelve months.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Mar 2026.