Parkinson's Disease (PD)NCT07422064
Validity and Reliability of the Six-Minute Pegboard Ring Test in Individuals With Parkinson's Disease
An observational study of Parkinson's Disease (PD) and Functional Capacity, run by Sanko University at 1 site in Turkey (Türkiye).
Trial summary
Parkinson's patients who volunteer to participate in the study will be included. Parkinson's patients participating in the study will be referred from the SANKO University Hospital Neurology Outpatient Clinic. Read more about this study
- Who is it for?
- Ages 40 to 75 years
- Conditions the study is for
- Parkinson's Disease (PD), Functional Capacity, Upper Extremity Function
- How many people
- 47 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Nov 2025to 6 Feb 2026
- How long will I take part?
- 3 Months
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients diagnosed with Parkinson's disease at the SANKO University Sani Konukoğlu Application and Research Hospital Neurology Outpatient Clinic
Who may be able to join
- Having been diagnosed with Parkinson's disease
- Being over 35 years of age
- Not having changed medications in the last 2 months
- Being able to walk with or without assistance
- Volunteering to participate in the study
Who cannot join
- Having a neurological disorder other than Parkinson's disease
- Having a visual impairment
- Having dyskinesia severe enough to interfere with the test
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Validity and Reliability of the Six-Minute Pegboard Ring Test for Assessing Functional Capacity and Upper Extremity Function in Individuals With Parkinson's Disease
Parkinson's patients who volunteer to participate in the study will be included. Parkinson's patients participating in the study will be referred from the SANKO University Hospital Neurology Outpatient Clinic. The assessments of patients referred from the Neurology Outpatient Clinic will be conducted at the SANKO University Physiotherapy and Rehabilitation Department Research Laboratory. The socio-demographic information of the included patients will be collected. Patients will then be grouped using the Hoehn-Yahr Staging Scale. Vital signs such as blood pressure, saturation, and pulse will be measured. Upper extremity muscle strength will be assessed using a dynamometer. Upper extremity performance will be assessed using the Nine-Hole Peg Test. The patient's fatigue will be assessed using the Fatigue Severity Scale, and upper extremity disability will be assessed using the Disability of the Arm, Shoulder, and Hand (DASH) questionnaire. The assessments will be conducted by Physiotherapist Rüveyda GÜRDAL.Except for the six-minute pegboard ring test, the other tests will evaluate the parameters required for an individual's upper extremity function. These parameters are balance, muscle strength, and fine motor skills. The six-minute pegboard ring test will be reassessed one week later by a different physiotherapist at the SANKO University Department of Physiotherapy and Rehabilitation Research Laboratory.
Read the detailed description
Parkinson's disease (PD) primarily arises from the progressive degeneration of the nigrostriatal dopaminergic pathway and neurons in the substantia nigra pars compacta, which aggregate in the form of Lewy bodies or Lewy neurites. PD is the second most common neurodegenerative disease after Alzheimer's disease, with a prevalence of 0.3% in the general population and 1-3% in the population over 65 years of age. As the disease progresses, the decrease in dopamine levels leads to resting tremor, bradykinesia, rigidity, impaired reflexes, depression, anxiety, emotional changes, cognitive impairment, difficulty swallowing, chewing and speaking, blank facial expressions, urinary problems, constipation, fatigue and sleep problems. Although the course and rate of progression of Parkinson's disease, which has an insidious onset, vary from patient to patient, the symptoms progress over the years in an extremely slow but gradually increasing manner. The asymmetric onset of the disease is very typical, and motor symptoms usually begin with resting tremor. Asymmetry in symptoms is maintained throughout the course of the disease, and bradykinesia develops to varying degrees in each patient. While there is a decrease in movement speed and amplitude (bradykinesia) in the early stages of the disease, it can progress over time and turn into akinesia. Initially, only the distal muscles are affected (micrographia, limited finger movements), but over time, all muscle groups become involved, and patients may eventually become unable to perform activities of daily living. We believe that the six-minute pegboard ring test may be valid and reliable in these individuals. If found to be valid and reliable, its use is recommended for the assessment of individuals diagnosed with Parkinson's disease. Assessments of patients referred from the SANKO University Hospital Neurology Outpatient Clinic will be conducted at the SANKO University Physiotherapy and Rehabilitation Department Research Laboratory. The socio-demographic information of the included patients will be collected. Subsequently, patients will be grouped using the Hoehn-Yahr Staging Scale. Vital signs such as blood pressure, saturation, and pulse will be checked. Upper extremity muscle strength will be assessed using a dynamometer. Upper extremity performance will be assessed using the Nine-Hole Peg Test. The patient's fatigue will be assessed using the Fatigue Severity Scale, and upper extremity disability will be assessed using the Disability of Arm, Shoulder, and Hand Questionnaire (DASH). The assessments will be conducted by Fzt. Rüveyda GÜRDAL. Except for the six-minute pegboard ring test, the other tests will evaluate the parameters required for an individual's upper extremity function. These parameters are balance, muscle strength, and fine motor skills. The six-minute pegboard ring test will be reassessed one week later by a different physiotherapist at the SANKO University Department of Physiotherapy and Rehabilitation Research Laboratory.
- Conditions
- Parkinson's Disease (PD), Functional Capacity, Upper Extremity Function, Validity and Safety
- Keywords
- Parkinson's Disease, Functional Capacity, Upper Extremity Function, Validity and Reliability
- Medical subject headings
- Parkinson Disease
What is being measured
The primary outcome is the main question the study is designed to answer.
Nine-Hole Peg Test
It is a simple, timed test used to assess an individual's fine motor skills, hand-eye coordination, and upper extremity function. The test board has 9 small holes. There are 9 small pegs in front of the person. The participant uses one hand to place the pegs into the holes one by one, then removes them again. This process should be completed in the shortest possible time. It is performed separately for each hand. The time is measured for evaluation.
Measured: 1 year
Blood Pressure
As our study involves the assessment of functional capacity and upper extremity function, these parameters will be measured during the test, as the individual's physiological state must remain stable
Measured: 1 year
Manual muscle test device
Muscle strength (right foot dorsi flexion, left foot dorsi flexion, right foot plantar flexion, left foot plantar flexion) will be measured with Commander Echo brand manual muscle test device. The participant will be asked to resist the resistance as much as possible and the maximum force will be recorded. After the participants are informed, 1 trial will be performed. Muscle strength measurement will be repeated 3 times and the average value will be recorded in kilograms.
Measured: 1 year
Fatigue Severity Scale
On the nine-item scale, the highest score is 63 and the lowest score is 9. An increase in the fatigue severity scale score indicates a higher level of fatigue.
Measured: 1 year
Wrist, Shoulder, and Hand Problems Survey(DASH)
This is a self-report questionnaire developed to assess functional limitations and pain levels in the arm, shoulder, and hand regions of individuals. It consists of a total of 30 questions. It inquires about the person's daily living activities, symptoms, and functionality over the past week. Subheadings: daily living activities (carrying objects, writing, combing hair, etc.), symptom assessment (pain, stiffness, weakness), social life and psychological impact, work/activity limitations. Each question is rated from 1 (no difficulty) to 5 (great difficulty/unable to perform). Score range: 0-100. 0 points: No limitations. 100 points: Maximum limitations and problems. At least 27 questions must be answered.
Measured: 1 year
Hoehn and Yahr Staging Scale
It is a 5-level classification system developed in 1967 and used to determine the clinical stage of Parkinson's disease based on motor symptoms. It is frequently used to determine the progression of the disease and support treatment planning.
The stages are as follows:
Stage 1: Only unilateral symptoms Stage 2: Bilateral symptoms, no balance issues Stage 3: Mild postural imbalance, still independent Stage 4: Significant motor impairment, requires some assistance Stage 5: Wheelchair-bound or bedridden
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Feb 2026
- Study start1 Nov 2025
- Primary completion15 Dec 2025
- Study completion6 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Parkinson's Disease (PD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Other
- Enrolment
- 47 participants (actual)
- Target duration
- 3 Months
Sponsor and investigators
- Lead sponsor
- Sanko University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hakan Polat, Sanko University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07422064
- Sponsor's protocol ID
- hakanpolat10
- Status last verified
- Feb 2026
- First submitted
- 11 Feb 2026
- Last updated
- 17 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: will be decided when the study is completed
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Validity and Reliability of the Six-Minute Pegboard Ring Test for Assessing Functional Capacity and Upper Extremity Function in Individuals With Parkinson's Disease
- ClinicalTrials.gov ID
- NCT07422064
- Acronym / sponsor ID
- hakanpolat10
- Conditions
- Parkinson's Disease (PD), Functional Capacity, Upper Extremity Function, Validity and Safety
- Keywords
- Parkinson's Disease, Functional Capacity, Upper Extremity Function, Validity and Reliability
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 47 participants (actual)
- Lead sponsor
- Sanko UniversityUniversity, hospital or other
- Study start
- 1 Nov 2025 (actual)
- Primary completion
- 15 Dec 2025 (actual)
- Study completion
- 6 Feb 2026 (actual)
- First posted
- 19 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Parkinson's patients who volunteer to participate in the study will be included. Parkinson's patients participating in the study will be referred from the SANKO University Hospital Neurology Outpatient Clinic. The assessments of patients referred from the Neurology Outpatient Clinic will be conducted at the SANKO University Physiotherapy and Rehabilitation Department Research Laboratory. The socio-demographic information of the included patients will be collected. Patients will then be grouped using the Hoehn-Yahr Staging Scale. Vital signs such as blood pressure, saturation, and pulse will be measured. Upper extremity muscle strength will be assessed using a dynamometer. Upper extremity performance will be assessed using the Nine-Hole Peg Test. The patient's fatigue will be assessed using the Fatigue Severity Scale, and upper extremity disability will be assessed using the Disability of the Arm, Shoulder, and Hand (DASH) questionnaire. The assessments will be conducted by Physiotherapist Rüveyda GÜRDAL.Except for the six-minute pegboard ring test, the other tests will evaluate the parameters required for an individual's upper extremity function. These parameters are balance, muscle strength, and fine motor skills. The six-minute pegboard ring test will be reassessed one week later by a different physiotherapist at the SANKO University Department of Physiotherapy and Rehabilitation Research Laboratory.
Detailed description
Parkinson's disease (PD) primarily arises from the progressive degeneration of the nigrostriatal dopaminergic pathway and neurons in the substantia nigra pars compacta, which aggregate in the form of Lewy bodies or Lewy neurites. PD is the second most common neurodegenerative disease after Alzheimer's disease, with a prevalence of 0.3% in the general population and 1-3% in the population over 65 years of age. As the disease progresses, the decrease in dopamine levels leads to resting tremor, bradykinesia, rigidity, impaired reflexes, depression, anxiety, emotional changes, cognitive impairment, difficulty swallowing, chewing and speaking, blank facial expressions, urinary problems, constipation, fatigue and sleep problems. Although the course and rate of progression of Parkinson's disease, which has an insidious onset, vary from patient to patient, the symptoms progress over the years in an extremely slow but gradually increasing manner. The asymmetric onset of the disease is very typical, and motor symptoms usually begin with resting tremor. Asymmetry in symptoms is maintained throughout the course of the disease, and bradykinesia develops to varying degrees in each patient. While there is a decrease in movement speed and amplitude (bradykinesia) in the early stages of the disease, it can progress over time and turn into akinesia. Initially, only the distal muscles are affected (micrographia, limited finger movements), but over time, all muscle groups become involved, and patients may eventually become unable to perform activities of daily living. We believe that the six-minute pegboard ring test may be valid and reliable in these individuals. If found to be valid and reliable, its use is recommended for the assessment of individuals diagnosed with Parkinson's disease. Assessments of patients referred from the SANKO University Hospital Neurology Outpatient Clinic will be conducted at the SANKO University Physiotherapy and Rehabilitation Department Research Laboratory. The socio-demographic information of the included patients will be collected. Subsequently, patients will be grouped using the Hoehn-Yahr Staging Scale. Vital signs such as blood pressure, saturation, and pulse will be checked. Upper extremity muscle strength will be assessed using a dynamometer. Upper extremity performance will be assessed using the Nine-Hole Peg Test. The patient's fatigue will be assessed using the Fatigue Severity Scale, and upper extremity disability will be assessed using the Disability of Arm, Shoulder, and Hand Questionnaire (DASH). The assessments will be conducted by Fzt. Rüveyda GÜRDAL. Except for the six-minute pegboard ring test, the other tests will evaluate the parameters required for an individual's upper extremity function. These parameters are balance, muscle strength, and fine motor skills. The six-minute pegboard ring test will be reassessed one week later by a different physiotherapist at the SANKO University Department of Physiotherapy and Rehabilitation Research Laboratory.
Study design
- Observational model
- Other
- Time perspective
- Other
- Target follow-up
- 3 Months
Who may qualify
- Ages
- 40 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients diagnosed with Parkinson's disease at the SANKO University Sani Konukoğlu Application and Research Hospital Neurology Outpatient Clinic
Key inclusion criteria (5 listed)
- Having been diagnosed with Parkinson's disease
- Being over 35 years of age
- Not having changed medications in the last 2 months
- Being able to walk with or without assistance
- Volunteering to participate in the study
Key exclusion criteria (3 listed)
- Having a neurological disorder other than Parkinson's disease
- Having a visual impairment
- Having dyskinesia severe enough to interfere with the test
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Nine-Hole Peg Test
Time frame: 1 year
It is a simple, timed test used to assess an individual's fine motor skills, hand-eye coordination, and upper extremity function. The test board has 9 small holes. There are 9 small pegs in front of the person. The participant uses one hand to place the pegs into the holes one by one, then removes them again. This process should be completed in the shortest possible time. It is performed separately for each hand. The time is measured for evaluation.
Blood Pressure
Time frame: 1 year
As our study involves the assessment of functional capacity and upper extremity function, these parameters will be measured during the test, as the individual's physiological state must remain stable
Manual muscle test device
Time frame: 1 year
Muscle strength (right foot dorsi flexion, left foot dorsi flexion, right foot plantar flexion, left foot plantar flexion) will be measured with Commander Echo brand manual muscle test device. The participant will be asked to resist the resistance as much as possible and the maximum force will be recorded. After the participants are informed, 1 trial will be performed. Muscle strength measurement will be repeated 3 times and the average value will be recorded in kilograms.
Fatigue Severity Scale
Time frame: 1 year
On the nine-item scale, the highest score is 63 and the lowest score is 9. An increase in the fatigue severity scale score indicates a higher level of fatigue.
Wrist, Shoulder, and Hand Problems Survey(DASH)
Time frame: 1 year
This is a self-report questionnaire developed to assess functional limitations and pain levels in the arm, shoulder, and hand regions of individuals. It consists of a total of 30 questions. It inquires about the person's daily living activities, symptoms, and functionality over the past week. Subheadings: daily living activities (carrying objects, writing, combing hair, etc.), symptom assessment (pain, stiffness, weakness), social life and psychological impact, work/activity limitations. Each question is rated from 1 (no difficulty) to 5 (great difficulty/unable to perform). Score range: 0-100. 0 points: No limitations. 100 points: Maximum limitations and problems. At least 27 questions must be answered.
Hoehn and Yahr Staging Scale
Time frame: 1 year
It is a 5-level classification system developed in 1967 and used to determine the clinical stage of Parkinson's disease based on motor symptoms. It is frequently used to determine the progression of the disease and support treatment planning. The stages are as follows: Stage 1: Only unilateral symptoms Stage 2: Bilateral symptoms, no balance issues Stage 3: Mild postural imbalance, still independent Stage 4: Significant motor impairment, requires some assistance Stage 5: Wheelchair-bound or bedridden
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2026.
- Individual participant dataSharing planned: Undecided. will be decided when the study is completed
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Parkinson's Disease (PD) and Functional Capacity, run by Sanko University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nine-Hole Peg Test (time frame: 1 year). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2026; AzTrials last refreshed its copy on 26 Oct 2026.