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Parkinson's Disease (PD)NCT07641556

The Effects of Tele-Rehabilitation-Based Dual-Task Upper Extremity Training in Patients With Parkinson's Disease

A study testing Conventional Single Task Upper Extremity Exercise Training, Clinic-Based Dual Task Upper Extremity Exercise Training and Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise Training in people with Parkinson's Disease (PD), run by Saglik Bilimleri Universitesi at 1 site in Turkey (Türkiye).

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The aim of this study is to compare the effects of tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training with clinical based dual-task upper extremity training and conventional single-task upper extremity training in patients with Parkinson's disease. Read more about this study

Who is it for?
Ages 40 years and older
Conditions the study is for
Parkinson's Disease (PD)
What is being tested?
Conventional Single Task Upper Extremity Exercise Training, Clinic-Based Dual Task Upper Extremity Exercise Training and Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise Training
Could I receive a placebo?
No, everyone receives an active treatment
How many people
40 participants
Where
1 siteTurkey (Türkiye)
Study dates
1 Jul 2026to 15 Dec 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 40 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Having been diagnosed with Parkinson's disease by a neurologist according to the UK Brain Bank criteria
  • Being in stage 3 or higher according to the Hoehn-Yahr Scale
  • Having a caregiver capable of providing the necessary assistance during tele-rehabilitation sessions and using the required equipment and programs.
  • Having the device and software to conduct remote video calls for tele-rehabilitation

Who cannot join

  • Presence of a neurological disease other than Parkinson's disease
  • Cognitive impairment (Standardized Mini Mental Test score less than 24)
  • Having undergone deep brain stimulation surgery
  • Having a visual, auditory, or perceptual problem
  • Having any orthopedic, rheumatological, or other condition that may affect hand functions

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Turkey (Türkiye)1 site, 1 recruiting
  • Gülhane Faculty of Physiotherapy and Rehabilitation

    Ankara, 06010

    Fatih SÖKE, +90 312 567 15 00, fatih.soke@sbu.edu.tr

    Recruiting

Other trials in Turkey (Türkiye)

About this study

Official title: Investigating the Effects of Tele-Rehabilitation-Based Dual-Task Upper Extremity Training in Patients With Parkinson's Disease

The aim of this study is to compare the effects of tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training with clinical based dual-task upper extremity training and conventional single-task upper extremity training in patients with Parkinson's disease. The main questions it aims to answer are:

  • Whether there are differences in motor symptoms, hand dexterity, upper extremity functions, grip strength, executive functions, daily living activities, and treatment satisfaction between tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training, clinical-based dual-task upper extremity training, and conventional single-task upper extremity training in patients with Parkinson's disease.
  • Whether there is a difference in telemedicine satisfaction between tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training in patients with Parkinson's disease.
Read more

Researchers will compare conventional single-task upper extremity training, clinical-based dual-task upper extremity training, tele-rehabilitation-based synchronous upper extremity training and tele-rehabilitation-based asynchronous upper extremity training.

Participants will:

  • Receive upper extremity exercise training at the study clinic or home, twice a week for approximately 60 minutes each time, for 6 weeks.
  • Participate in assessments at the study clinic before and after exercise training.
Being tested
Conventional Single Task Upper Extremity Exercise Training, Clinic-Based Dual Task Upper Extremity Exercise Training, Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise Training, Tele-Rehabilitation Based Asynchronous Dual Task Upper Extremity Exercise Training
Keywords
Parkinson's Disease, Dual Task Training, Upper Extremity, Tele-Rehabilitation
Medical subject headings
Parkinson Disease

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Conventional Single Task Upper Extremity Exercise TrainingOther

    Conventional single task upper extremity exercise training at clinical setting. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performed for 3 minutes each, in a random order. A 2-minute rest period will be given between each activity.

  • Clinic-Based Dual Task Upper Extremity Exercise TrainingOther

    Dual task upper extremity exercise training at clinical setting. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performed simultaneously with three randomly selected cognitive tasks (arithmetic task, verbal fluency, digit span) for 3 minutes each, in a random order. A 2-minute rest period will be given between each activity.

  • Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise TrainingOther

    Dual task upper extremity exercise training at patient's home, synchronous with a researcher via tele-rehabilitation method. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performed simultaneously with three randomly selected cognitive tasks (arithmetic task, verbal fluency, digit span) for 3 minutes each, in a random order. A 2-minute rest period will be given between each activity.

  • Tele-Rehabilitation Based Asynchronous Dual Task Upper Extremity Exercise TrainingOther

    Dual task upper extremity exercise training at patient's home, asynchronous under a researcher supervision. It will be carried out according to the pre-determined schedule and will be video recorded. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performed simultaneously with three randomly selected cognitive tasks (arithmetic task, verbal fluency, digit span) for 3 minutes each, in a random order. A 2-minute rest period will be given between each activity.

Study groups in NCT07641556
Study groupRoleWhat they receive
Single Task TrainingActive comparatorConventional, clinic-based, single task upper extremity training
Receives: Other: Conventional Single Task Upper Extremity Exercise Training
Clinic-Based Dual Task TrainingExperimentalClinic-based, dual task upper extremity training
Receives: Other: Clinic-Based Dual Task Upper Extremity Exercise Training
Tele-Rehabilitation Based Synchronous Dual Task TrainingExperimentalTele-rehabilitation based synchronous dual task upper extremity training
Receives: Other: Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise Training
Tele-Rehabilitation Based Asynchronous Dual Task TrainingExperimentalTele-rehabilitation based asynchronous dual task upper extremity training
Receives: Other: Tele-Rehabilitation Based Asynchronous Dual Task Upper Extremity Exercise Training

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Unified Parkinson's Disease Rating Scale (UPDRS) - PART 3

    UPDRS is a reliable and valid scale that assesses cognitive skills, mood, daily living activities, motor skills, motor fluctuations, dyskinesias and autonomic dysfunction and is widely used in clinical studies and research in Parkinson's disease. The motor symptoms section, which is the third section of this scale, will be used.

    Measured: From enrollment to the end of training at 6 weeks

  2. Hoehn & Yahr Scale

    It is a staging system that provides information quickly in determining the severity and symptoms of Parkinson's disease.

    Measured: From enrollment to the end of treatment at 6 weeks

  3. Nine-Hole Peg Test

    During the test, individuals use only one hand to pick up nine wooden pegs one by one and insert them into the holes as quickly as possible. After inserting all the pegs, they quickly place them back into the container one by one. The timer starts when the individual touches the first peg and ends when the last peg is placed back into the container.

    Measured: From enrollment to the end of treatment at 6 weeks

  4. Coin Rotation Test

    This test assesses the coordination of independent finger movements. In this test, the person is asked to rotate a coin 180 degrees as many times as possible between their thumb, index finger, and middle finger within 10 seconds without dropping it. The person's performance is video recorded and later analyzed. An increase in the number of times the patient rotates the coin within 10 seconds indicates better fine motor skills.

    Measured: From enrollment to the end of treatment at 6 weeks

  5. Manual Ability Measure-36

    This is a 36-question survey that assesses fine motor skills based on individual self-reports. The survey includes questions related to daily life, such as drinking water, tying shoelaces, brushing teeth, and turning book pages. Each question is scored from 0 (almost impossible) to 4 (easy). The resulting score is converted to a 100-point system. Higher scores indicate good fine motor skills.

    Measured: From enrollment to the end of treatment at 6 weeks

  6. Grip Strength

    Grip strength will be assessed using a Jamar hand dynamometer (JAMAR®, Performance Health Holdings, Inc., USA). During the tests, the individual will be positioned in a chair with the arm at the side of the body, the elbow flexed at 90°, and the wrist in a neutral position. Individuals will be asked to make a fist to assess their grip strength.

    Measured: From enrollment to the end of treatment at 6 weeks

  7. Trail Making Test

    It is used to assess executive functions and attention. The test consists of two parts, A and B. In part A, the individual is asked to combine numbers from 1 to 25, and the completion time is recorded. In part B, the individual completes a sequence where each number corresponds to a letter, and the completion time is recorded.

    Measured: From enrollment to the end of treatment at 6 weeks

  8. Unified Parkinson's Disease Rating Scale (UPDRS) - PART 2

    It consists of thirteen items. The assessment is based on anamnesis information regarding how the patient functions in various activities. The presence of sensory complaints that may be related to tremor and parkinsonism is also included in this section as they can affect daily living activities. Each item is evaluated using a scoring system between '0' and '4'.

    Measured: From enrollment to the end of treatment at 6 weeks

  9. Dual-Task Impact on Daily-Living Activities Questionnaire

    This test is used to assess the difficulties experienced in daily tasks involving dual task execution. It consists of 19 questions, with a scale of 0 (not difficult at all) to 4 (extremely difficult). A higher overall score indicates a higher perceived level of difficulty when performing dual tasks during daily life activities.

    Measured: From enrollment to the end of treatment at 6 weeks

Secondary outcomes (2)
  1. Treatment Satisfaction

    Patient satisfaction with treatment will be assessed post-treatment using a 100 mm long visual-analog scale.

    Measured: At end of treatment at 6 weeks

  2. Telemedicine Satisfaction Questionnaire

    This survey consists of 14 items. It assesses patients' satisfaction levels with the software or system they use for treatment or other remote rehabilitation services. The total score ranges from 14 to 70, with a maximum of 5 points per question. A higher score indicates higher satisfaction.

    Measured: At end of treatment at 6 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted11 Jun 2026
  2. Study start1 Jul 2026
  3. Primary completion1 Dec 2026 (estimated)
  4. Study completion15 Dec 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
40 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07641556
Sponsor's protocol ID
2026-151
Status last verified
Oct 2026
First submitted
6 Jun 2026
Last updated
19 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing Conventional Single Task Upper Extremity Exercise Training, Clinic-Based Dual Task Upper Extremity Exercise Training and Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise Training in people with Parkinson's Disease (PD), run by Saglik Bilimleri Universitesi at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Fatih SÖKE (+90 312 567 15 00, fatih.soke@sbu.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Unified Parkinson's Disease Rating Scale (UPDRS) - PART 3 (time frame: From enrollment to the end of training at 6 weeks). The study lists 9 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.

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