Osteoarthritis, KneePDNCT07342166
Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty
A study testing Patellar Denervation in people with Osteoarthritis, Knee, run by Queen Savang Vadhana Memorial Hospital, Thailand at 1 site in Thailand.
Trial summary
This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing. Read more about this study
- Who is it for?
- Ages 55 to 85 years
- Conditions the study is for
- Osteoarthritis, Knee
- What is being tested?
- Patellar Denervation
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 64 participants
- Where
- 1 siteThailand
- Study dates
- 8 Aug 2023to 21 Jun 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 55-85 years old
- Knee osteoarthritis
- Plan for total knee arthroplasty after failed conservative treatment for at least 3 months
Who cannot join
- Previous history of trauma, fracture or open surgery on the same knee
- Inflammatory arthritis or Crystal-induced arthritis
- Patellar instability or isolated patellofemoral osteoarthritis
- Unable to answer questionnaire
- Cannot tolerate surgery due to medical comorbidities
Trial locations and contacts
1 site in 1 country.
Thailand1 site
Chalathorn Kulthonchalanan
Chon Buri, Changwat Chon Buri, 20110
About this study
Official title: Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty: A Randomized Controlled Trial
This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.
Read the detailed description
This study is a prospective, double-blind randomized controlled trial conducted at Queen Savang Vadhana Memorial Hospital between 2023 and 2025. The aim of the study is to assess the effect of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.
Sixty-four patients were enrolled and randomly assigned to either the patellar denervation group (PD) or the non-denervation group (NPD), with 32 participants in each group.
- Conditions
- Osteoarthritis, Knee
- Being tested
- Patellar Denervation
- Keywords
- Patellar denervation, Total knee arthroplasty, Total knee replacement
- Medical subject headings
- Osteoarthritis, Knee
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Patellar DenervationProcedure or surgery
Electrocautery patella circumferentially during total knee arthroplasty
| Study group | Role | What they receive |
|---|---|---|
| Patellar Denervation | Experimental | Not described Receives: Procedure: Patellar Denervation |
| Non-Patellar Denervation | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual analog scale score for knee pain
Measured: 2 weeks, 6 weeks, 3 months, 6 months, and 12 months
Secondary outcomes (3)
Kujala score
Measured: 3 months, 1 year
Knee Society score
Measured: 3 months, 1 year
Timed up and go test
Measured: 3 months, 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jan 2026
- Study start8 Aug 2023
- Primary completion21 Jun 2025
- Study completion21 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Osteoarthritis, KneeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 64 participants (actual)
Sponsor and investigators
- Lead sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07342166
- Sponsor's protocol ID
- 021/2566
- Acronym
- PD
- Status last verified
- Jan 2026
- First submitted
- 25 Dec 2025
- Last updated
- 15 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Data was save in form of Google sheet
Study at a glance
From the registry record, last updated by the sponsor on 15 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07342166
- Acronym / sponsor ID
- PD / 021/2566
- Conditions
- Osteoarthritis, Knee
- Keywords
- Patellar denervation, Total knee arthroplasty, Total knee replacement
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 64 participants (actual)
- Lead sponsor
- Queen Savang Vadhana Memorial Hospital, ThailandUniversity, hospital or other
- Study start
- 8 Aug 2023 (actual)
- Primary completion
- 21 Jun 2025 (actual)
- Study completion
- 21 Jun 2025 (actual)
- First posted
- 15 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.
Detailed description
This study is a prospective, double-blind randomized controlled trial conducted at Queen Savang Vadhana Memorial Hospital between 2023 and 2025. The aim of the study is to assess the effect of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.
Sixty-four patients were enrolled and randomly assigned to either the patellar denervation group (PD) or the non-denervation group (NPD), with 32 participants in each group.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Patellar Denervation | Experimental | Procedure: Patellar Denervation |
| Non-Patellar Denervation | No intervention | – |
Who may qualify
- Ages
- 55 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Age 55-85 years old
- Knee osteoarthritis
- Plan for total knee arthroplasty after failed conservative treatment for at least 3 months
Key exclusion criteria (5 listed)
- Previous history of trauma, fracture or open surgery on the same knee
- Inflammatory arthritis or Crystal-induced arthritis
- Patellar instability or isolated patellofemoral osteoarthritis
- Unable to answer questionnaire
- Cannot tolerate surgery due to medical comorbidities
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Patellar DenervationElectrocautery patella circumferentially during total knee arthroplasty | Procedure or surgery | Patellar Denervation |
Primary outcome
Visual analog scale score for knee pain
Time frame: 2 weeks, 6 weeks, 3 months, 6 months, and 12 months
3 secondary outcomes
Kujala score
Time frame: 3 months, 1 year
Knee Society score
Time frame: 3 months, 1 year
Timed up and go test
Time frame: 3 months, 1 year
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jan 2026.
- Individual participant dataSharing planned: No. Data was save in form of Google sheet
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Patellar Denervation in people with Osteoarthritis, Knee, run by Queen Savang Vadhana Memorial Hospital, Thailand at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual analog scale score for knee pain (time frame: 2 weeks, 6 weeks, 3 months, 6 months, and 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2026.