EndometriosisNCT07202741
Effect of Yoga on Pelvic Pain and Quality of Life in Endometriosis
A study testing yoga group in people with Endometriosis, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).
Trial summary
Women may experience loss of work/education and disruption in family relationships due to endometriosis-related symptoms. While surgical and medical treatments provide effective results in the management of endometriosis-related pain, the rate of recurrence is high. Read more about this study
- Who is it for?
- Ages 18 to 55 years, women only
- Conditions the study is for
- Endometriosis
- What is being tested?
- yoga group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 30 Jan 2024to 3 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Women over the age of 18 diagnosed with endometriosis
- Experiencing pelvic pain for at least 6 months (VAS score ≥4)
- Not pregnant
- Have not practiced yoga before
- Able to participate with internet access
- No communication barriers
- No health problems that would prevent practicing yoga
- No psychiatric health problems
Who cannot join
- Becoming pregnant during the study
- Developing a health problem that prevents yoga
- Failing to participate in at least two of the 8-week yoga program
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of Yoga on Pelvic Pain and Quality of Life in Women With Endometriosis
Women may experience loss of work/education and disruption in family relationships due to endometriosis-related symptoms. While surgical and medical treatments provide effective results in the management of endometriosis-related pain, the rate of recurrence is high. There is a need for nurse-led studies to identify supportive practices and interventions that can improve the quality of life and comfort of women with endometriosis, as well as to assess the effectiveness of these interventions. Nurses, with their holistic and patient-centered approach, play a crucial role. Therapeutic communication between nurses and patients during the diagnosis, treatment, and follow-up of endometriosis will contribute to disease management.
While there are limited studies worldwide examining the effects of yoga on pain and quality of life in women with endometriosis, no studies have been found in our country on the effectiveness of yoga on endometriosis. Therefore, this study was designed to contribute to the literature and evaluate the effects of yoga on pelvic pain and quality of life in women with endometriosis.
- Conditions
- Endometriosis
- Being tested
- yoga group
- Keywords
- Endometriosis, pelvic pain, quality of life, yoga
- Medical subject headings
- Endometriosis, Pelvic Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
yoga groupOther
Also called yoga
A total of 50 minutes of hatha yoga practice was performed three times a week for 12 weeks.
- In the first week, two days of face-to-face yoga practice with the researcher.
- During the eighth week, online yoga practices were held twice a week via Skype with the researcher and one yoga practice per week (a list was made for the group the researcher would create via WhatsApp).
The participants were supported with weekly motivation and follow-up information to continue practicing yoga at least twice a week for the next four weeks. All yoga sessions included a 10-minute warm-up and breathing session, 50 minutes of hatha yoga, 15 minutes of relaxation and separation, and 5 minutes of feedback. At the end of the session, the participants received support regarding correct yoga asanas, motivation, and consistency.
| Study group | Role | What they receive |
|---|---|---|
| yoga group | Experimental | At the patient's first meeting, they were given an educational brochure and booklet about endometriosis and yoga. The researcher, who received an RYS-200 Yoga Instructor Certificate from the Turkish Yoga Federation, prepared a yoga video for endometriosis patients with a yoga instructor and shared it on Google Drive. The women practiced yoga according to the designated days and times. Yoga practiced three times a week for a total of eight weeks.
Until the end of the 8th week, online yoga practices continued via Skype with the researcher twice a week and yoga practices that the participants would practice themselves once a week.
Participants were encouraged to continue their yoga practice at least twice a week for the next four weeks with weekly motivational and follow-up messages. At the end of the 12 weeks, participants were contacted by phone to assess their yoga practice attendance and satisfaction, and they were asked to complete forms. Receives: Other: yoga group |
| control group | No intervention | During the initial patient encounter, the researcher provided information about endometriosis, its symptoms, diagnosis, pain management methods, and ways to adopt a healthy lifestyle, all in a 20-minute session using a brochure and educational booklet. Participants were provided with a printed version of the educational booklet and brochure for later use. No intervention was administered for 8 weeks, and routine follow-up was conducted. At the end of weeks 4, 8, and 12, the Endometriosis Pain Monitoring Form, Visual Analog Scale (VAS), McGill Pain Scale Short Form, Endometriosis Health Profile Questionnaire (EHP-5), and Psychological Well-Being Scale were completed via telephone. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analog Scale for Pelvic Pain
The Visual Analog Scale is a widely used scale in daily practice to measure perceived pain. It consists of a measured horizontal or vertical line. A value of "0" indicates no pain on a 10 cm neck, a value of "1-4" indicates mild pain, "5-6" indicates moderate pain, and "7-10" indicates severe pain. A value of "10" indicates the most severe pain.
Measured: 12 weeks
McGill Pain Scale Short Form for Pelvic Pain
The McGill Pain Scale Short Form consists of three sections. The first section contains 15 word groups describing the sensory/perceptual pain dimension (the first 11 words) and the emotional/emotional pain dimension (the last four words). Increasing total pain scores indicate an increase in the individual's perception of pain. The second section of the scale determines the severity of an individual's pain using a VAS. The third section uses a six-point Likert-type scale to determine the severity of the pain. The scale consists of expressive values ranging from 0 = no pain, 1 = mild, 2 = bothersome, 3 = distressing, 4 = excruciating, and 5 = unbearable pain. A low score indicates that the individual's pain intensity is generally low or mild, while a high score indicates high or severe pain.
Measured: 12 weeks
Quality of life (Endometriosis Health Profile Questionnaire-5 score)
The Endometriosis Health Profile Questionnaire (EHP-5) consists of core (pain, control and powerlessness, emotional well-being, social support, and body image) and modular (work life, relationship with children, sexual life, healthcare professionals, treatment, and infertility) sections. Each item is scored on a five-point scale from 0 to 4, corresponding to never, rarely, sometimes, often, and always. Scores are converted to a scale ranging from 0 to 100, representing best and worst health status, respectively. Lower scores indicate better quality of life, whereas higher scores indicate poorer quality of life.
Measured: 12 weeks
Psychological well-being (Psychological Well-being Scale score)
The eight-item Psychological Well-Being Scale describes important elements of human functioning, from positive relationships and feelings of competence to having a meaningful and purposeful life. The scale's items are answered on a scale of 1-7, from strongly disagree (1) to strongly agree (7). All items are worded positively. Scores range from 8 (if all items are answered "strongly disagree") to 56 (if all items are answered "strongly agree"). A higher score indicates a higher level of psychological well-being.
Measured: 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Oct 2025
- Study start30 Jan 2024
- Primary completion17 Mar 2025
- Study completion3 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for EndometriosisStudies of the same condition, open and under way.
- More trials run by Istanbul University - CerrahpasaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- It is an experimental study consisting of 2 groups, a randomized controlled experiment and a control group, using a pre-test-post-test design.
- Masking
- None (open label)
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Istanbul University - Cerrahpasa
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Gizem Cevik, Istanbul University - Cerrahpasa
- Investigators
- İlkay GÜNGÖR SATILMIŞ, Professor Dr., Principal investigator, Florence Nightingale Faculty of Nursing, Department of Nursing, Department of Women's Health and Disease Nursing
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07202741
- Sponsor's protocol ID
- IstanbulUC-HEM-GÇ-01
- Status last verified
- Sep 2025
- First submitted
- 23 Sep 2025
- Last updated
- 27 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Yoga on Pelvic Pain and Quality of Life in Women With Endometriosis
- ClinicalTrials.gov ID
- NCT07202741
- Acronym / sponsor ID
- IstanbulUC-HEM-GÇ-01
- Conditions
- Endometriosis
- Keywords
- Endometriosis, pelvic pain, quality of life, yoga
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Istanbul University - CerrahpasaUniversity, hospital or other
- Study start
- 30 Jan 2024 (actual)
- Primary completion
- 17 Mar 2025 (actual)
- Study completion
- 3 Jul 2025 (actual)
- First posted
- 2 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Women may experience loss of work/education and disruption in family relationships due to endometriosis-related symptoms. While surgical and medical treatments provide effective results in the management of endometriosis-related pain, the rate of recurrence is high. There is a need for nurse-led studies to identify supportive practices and interventions that can improve the quality of life and comfort of women with endometriosis, as well as to assess the effectiveness of these interventions. Nurses, with their holistic and patient-centered approach, play a crucial role. Therapeutic communication between nurses and patients during the diagnosis, treatment, and follow-up of endometriosis will contribute to disease management.
While there are limited studies worldwide examining the effects of yoga on pain and quality of life in women with endometriosis, no studies have been found in our country on the effectiveness of yoga on endometriosis. Therefore, this study was designed to contribute to the literature and evaluate the effects of yoga on pelvic pain and quality of life in women with endometriosis.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- It is an experimental study consisting of 2 groups, a randomized controlled experiment and a control group, using a pre-test-post-test design.
| Arm | Type | Receives |
|---|---|---|
| yoga group | Experimental | Other: yoga groupAt the patient's first meeting, they were given an educational brochure and booklet about endometriosis and yoga. The researcher, who received an RYS-200 Yoga Instructor Certificate from the Turkish Yoga Federation, prepared a yoga video for endometriosis patients with a yoga instructor and shared it on Google Drive. The women practiced yoga according to the designated days and times. Yoga practiced three times a week for a total of eight weeks. Until the end of the 8th week, online yoga practices continued via Skype with the researcher twice a week and yoga practices that the participants would practice themselves once a week. Participants were encouraged to continue their yoga practice at least twice a week for the next four weeks with weekly motivational and follow-up messages. At the end of the 12 weeks, participants were contacted by phone to assess their yoga practice attendance and satisfaction, and they were asked to complete forms. |
| control group | No intervention | –During the initial patient encounter, the researcher provided information about endometriosis, its symptoms, diagnosis, pain management methods, and ways to adopt a healthy lifestyle, all in a 20-minute session using a brochure and educational booklet. Participants were provided with a printed version of the educational booklet and brochure for later use. No intervention was administered for 8 weeks, and routine follow-up was conducted. At the end of weeks 4, 8, and 12, the Endometriosis Pain Monitoring Form, Visual Analog Scale (VAS), McGill Pain Scale Short Form, Endometriosis Health Profile Questionnaire (EHP-5), and Psychological Well-Being Scale were completed via telephone. |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (8 listed)
- Women over the age of 18 diagnosed with endometriosis
- Experiencing pelvic pain for at least 6 months (VAS score ≥4)
- Not pregnant
- Have not practiced yoga before
- Able to participate with internet access
Key exclusion criteria (3 listed)
- Becoming pregnant during the study
- Developing a health problem that prevents yoga
- Failing to participate in at least two of the 8-week yoga program
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| yoga groupAlso: yogaA total of 50 minutes of hatha yoga practice was performed three times a week for 12 weeks. * In the first week, two days of face-to-face yoga practice with the researcher. * During the eighth week, online yoga practices were held twice a week via Skype with the researcher and one yoga practice per week (a list was made for the group the researcher would create via WhatsApp). The participants were supported with weekly motivation and follow-up information to continue practicing yoga at least twice a week for the next four weeks. All yoga sessions included a 10-minute warm-up and breathing session, 50 minutes of hatha yoga, 15 minutes of relaxation and separation, and 5 minutes of feedback. At the end of the session, the participants received support regarding correct yoga asanas, motivation, and consistency. | Other | yoga group |
Primary outcome
Visual Analog Scale for Pelvic Pain
Time frame: 12 weeks
The Visual Analog Scale is a widely used scale in daily practice to measure perceived pain. It consists of a measured horizontal or vertical line. A value of "0" indicates no pain on a 10 cm neck, a value of "1-4" indicates mild pain, "5-6" indicates moderate pain, and "7-10" indicates severe pain. A value of "10" indicates the most severe pain.
McGill Pain Scale Short Form for Pelvic Pain
Time frame: 12 weeks
The McGill Pain Scale Short Form consists of three sections. The first section contains 15 word groups describing the sensory/perceptual pain dimension (the first 11 words) and the emotional/emotional pain dimension (the last four words). Increasing total pain scores indicate an increase in the individual's perception of pain. The second section of the scale determines the severity of an individual's pain using a VAS. The third section uses a six-point Likert-type scale to determine the severity of the pain. The scale consists of expressive values ranging from 0 = no pain, 1 = mild, 2 = bothersome, 3 = distressing, 4 = excruciating, and 5 = unbearable pain. A low score indicates that the individual's pain intensity is generally low or mild, while a high score indicates high or severe pain.
Quality of life (Endometriosis Health Profile Questionnaire-5 score)
Time frame: 12 weeks
The Endometriosis Health Profile Questionnaire (EHP-5) consists of core (pain, control and powerlessness, emotional well-being, social support, and body image) and modular (work life, relationship with children, sexual life, healthcare professionals, treatment, and infertility) sections. Each item is scored on a five-point scale from 0 to 4, corresponding to never, rarely, sometimes, often, and always. Scores are converted to a scale ranging from 0 to 100, representing best and worst health status, respectively. Lower scores indicate better quality of life, whereas higher scores indicate poorer quality of life.
Psychological well-being (Psychological Well-being Scale score)
Time frame: 12 weeks
The eight-item Psychological Well-Being Scale describes important elements of human functioning, from positive relationships and feelings of competence to having a meaningful and purposeful life. The scale's items are answered on a scale of 1-7, from strongly disagree (1) to strongly agree (7). All items are worded positively. Scores range from 8 (if all items are answered "strongly disagree") to 56 (if all items are answered "strongly agree"). A higher score indicates a higher level of psychological well-being.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
İlkay GÜNGÖR SATILMIŞ, Professor Dr. principal investigator
Florence Nightingale Faculty of Nursing, Department of Nursing, Department of Women's Health and Disease Nursing
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing yoga group in people with Endometriosis, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analog Scale for Pelvic Pain (time frame: 12 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026.