Hamstring TightnessTightnessNCT07178132
Use of PNF and Tissue Flossing to Treat Hamstring Tightness in Young Female Students
A study testing tissue floss band and Proprioceptive Neuromuscular Facilitation in people with Hamstring Tightness and Muscle Tightness, run by Sakshi Negi at 1 site in India.
Trial summary
The goal of this clinical trial is to learn tissue flossing and proprioceptive neuromuscular facilitation effect in treating hamstring muscle tightness. The main questions it aims to answer are: 1. which technique is more useful in giving instant relaxation of hamstring muscle 2. Read more about this study
- Who is it for?
- Ages 18 to 25 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Hamstring Tightness, Muscle Tightness
- What is being tested?
- tissue floss band and Proprioceptive Neuromuscular Facilitation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteIndia
- Study dates
- 2 Feb 2024to 15 Apr 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female subjects were included in the study
- Subjects with hamstring muscle tightness were included
- Subjects between the age group of 18-25 years were included
Who cannot join
- Male subjects
- Subject who didn't fulfill the age criteria
- Subject with hamstring tear or other knee ligament injury
- Any history of lower limb surgery dating back a year
- Subjects with Lower back pain or any neurological compromise in the lower limb
- Any acute injury like a sprain, strain, and open wound
- Subjects who had latex allergies
- Subjects with venous thrombotic disease, heart disease, respiratory illness, and dermatitis, in their lower legs were excluded
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparative Effects of Tissue Flossing and Proprioceptive Neuromuscular Facilitation on Hamstring Flexibility and Knee Range of Motion in Young Female Students
The goal of this clinical trial is to learn tissue flossing and proprioceptive neuromuscular facilitation effect in treating hamstring muscle tightness.
The main questions it aims to answer are:
Read more
- which technique is more useful in giving instant relaxation of hamstring muscle
- can these technique increase muscle flexibility and knee motion
Researchers will compare Tissue flossing to a PNF (Proprioceptive neuromuscular facilitation) to see which on is more effective.
Participant will:
- be provided one technique either tissue flossing or PNF in first day
- physiotherapist will immediately measure the the change in flexibility or knee motion
- another technique will be applied after 1 week 3. again change in flexibility and knee motion will be recorded
- Conditions
- Hamstring Tightness, Muscle Tightness
- Being tested
- tissue floss band, Proprioceptive Neuromuscular Facilitation
- Keywords
- tightness, tissue flossing, proprioceptive neuromuscular facilitation, Hamstring tightness, flexibility
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
tissue floss bandOther
Also called Floss band
Floss band is wrapped in thigh from distal to proximal for 2 minutes. during this period patient is asked to actively perform movement for 2 minute, after that the band is removed and repeated once more. Immediately followed by flexibility measurements
Proprioceptive Neuromuscular FacilitationOther
Proprioceptive Neuromuscular Facilitation (PNF) Stretching using the hold-relax method: participants perform an isometric contraction of the hamstring at the end of its stretch range , followed by relaxation and passive stretch, then flexibility assessed similarly
| Study group | Role | What they receive |
|---|---|---|
| Tissue Flossing Arm | Experimental | Application of tissue floss band to hamstring muscle at moderate tension for 2 minutes, followed by flexibility testing via AKET (Active Knee Extension Test), PKET (Passive Knee Extension Test), SLR (Straight Leg Raise), and Sit-and-Reach. Receives: Other: tissue floss band |
| PNF Hold-Relax Arm | Active comparator | Standard PNF hold-relax stretching technique of hamstring, followed by flexibility testing via AKET (Active Knee Extension Test), PKET (Passive Knee Extension Test), SLR (Straight Leg Raise), and Sit-and-Reach. Receives: Other: Proprioceptive Neuromuscular Facilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Active Knee Extension Test
With the participant supine and the hip flexed to 90°, the participant actively extends the knee. A goniometer was used to records the knee extension angle. Three trials are performed and the mean is used for analysis.
Measured: From enrollment to the end of treatment at 1 week
Passive Knee Extension Test
With the participant supine and the hip flexed to 90°, the examiner passively extends the knee until the first onset of resistance. A goniometer is used to records the knee extension angle. Three trials are performed and the mean is used.
Measured: From enrollment to the end of treatment at 1 week
Straight Leg Raise
With the participant supine, the examiner passively raises the extended leg until resistance . A goniometer at the hip measures maximum hip flexion angle (degrees). Three trials are performed and the mean is used.
Measured: From enrollment to the end of treatment at 1 week
Sit-and-Reach Test
The participant sits with legs extended and reaches forward along a standard sit-and-reach box . After a warm-up, three trials are performed and the mean score (cm) is recorded.
Measured: From enrollment to the end of treatment at 1 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Sep 2025
- Study start2 Feb 2024
- Primary completion10 Apr 2024
- Study completion15 Apr 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hamstring TightnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sakshi Negi
- Sponsor type
- University, hospital or other
- Collaborators
- Guru Nanak Dev University
- Responsible party
- Sponsor-investigator, Sakshi Negi, Guru Nanak Dev University
- Investigators
- Manpreet Kaur, MPT, Study director, Guru Nanak Dev University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07178132
- Sponsor's protocol ID
- 2250/HG
- Acronym
- Tightness
- Status last verified
- Sep 2025
- First submitted
- 10 Sep 2025
- Last updated
- 24 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: I did not include individual participant data in ClinicalTrials.gov to protect participant privacy and confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Tissue Flossing and Proprioceptive Neuromuscular Facilitation on Hamstring Flexibility and Knee Range of Motion in Young Female Students
- ClinicalTrials.gov ID
- NCT07178132
- Acronym / sponsor ID
- Tightness / 2250/HG
- Conditions
- Hamstring Tightness, Muscle Tightness
- Keywords
- tightness, tissue flossing, proprioceptive neuromuscular facilitation, Hamstring tightness, flexibility
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Sakshi NegiUniversity, hospital or other
- Collaborators
- Guru Nanak Dev University
- Study start
- 2 Feb 2024 (actual)
- Primary completion
- 10 Apr 2024 (actual)
- Study completion
- 15 Apr 2024 (actual)
- First posted
- 17 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn tissue flossing and proprioceptive neuromuscular facilitation effect in treating hamstring muscle tightness.
The main questions it aims to answer are:
- which technique is more useful in giving instant relaxation of hamstring muscle
- can these technique increase muscle flexibility and knee motion
Researchers will compare Tissue flossing to a PNF (Proprioceptive neuromuscular facilitation) to see which on is more effective.
Participant will:
- be provided one technique either tissue flossing or PNF in first day
- physiotherapist will immediately measure the the change in flexibility or knee motion
- another technique will be applied after 1 week 3. again change in flexibility and knee motion will be recorded
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Tissue Flossing Arm | Experimental | Other: tissue floss bandApplication of tissue floss band to hamstring muscle at moderate tension for 2 minutes, followed by flexibility testing via AKET (Active Knee Extension Test), PKET (Passive Knee Extension Test), SLR (Straight Leg Raise), and Sit-and-Reach. |
| PNF Hold-Relax Arm | Active comparator | Other: Proprioceptive Neuromuscular FacilitationStandard PNF hold-relax stretching technique of hamstring, followed by flexibility testing via AKET (Active Knee Extension Test), PKET (Passive Knee Extension Test), SLR (Straight Leg Raise), and Sit-and-Reach. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Female subjects were included in the study
- Subjects with hamstring muscle tightness were included
- Subjects between the age group of 18-25 years were included
Key exclusion criteria (8 listed)
- Male subjects
- Subject who didn't fulfill the age criteria
- Subject with hamstring tear or other knee ligament injury
- Any history of lower limb surgery dating back a year
- Subjects with Lower back pain or any neurological compromise in the lower limb
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| tissue floss bandAlso: Floss bandFloss band is wrapped in thigh from distal to proximal for 2 minutes. during this period patient is asked to actively perform movement for 2 minute, after that the band is removed and repeated once more. Immediately followed by flexibility measurements | Other | Tissue Flossing Arm |
| Proprioceptive Neuromuscular FacilitationProprioceptive Neuromuscular Facilitation (PNF) Stretching using the hold-relax method: participants perform an isometric contraction of the hamstring at the end of its stretch range , followed by relaxation and passive stretch, then flexibility assessed similarly | Other | PNF Hold-Relax Arm |
Primary outcome
Active Knee Extension Test
Time frame: From enrollment to the end of treatment at 1 week
With the participant supine and the hip flexed to 90°, the participant actively extends the knee. A goniometer was used to records the knee extension angle. Three trials are performed and the mean is used for analysis.
Passive Knee Extension Test
Time frame: From enrollment to the end of treatment at 1 week
With the participant supine and the hip flexed to 90°, the examiner passively extends the knee until the first onset of resistance. A goniometer is used to records the knee extension angle. Three trials are performed and the mean is used.
Straight Leg Raise
Time frame: From enrollment to the end of treatment at 1 week
With the participant supine, the examiner passively raises the extended leg until resistance . A goniometer at the hip measures maximum hip flexion angle (degrees). Three trials are performed and the mean is used.
Sit-and-Reach Test
Time frame: From enrollment to the end of treatment at 1 week
The participant sits with legs extended and reaches forward along a standard sit-and-reach box . After a warm-up, three trials are performed and the mean score (cm) is recorded.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2025.
- Individual participant dataSharing planned: No. I did not include individual participant data in ClinicalTrials.gov to protect participant privacy and confidentiality.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Manpreet Kaur, MPT study director
Guru Nanak Dev University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing tissue floss band and Proprioceptive Neuromuscular Facilitation in people with Hamstring Tightness and Muscle Tightness, run by Sakshi Negi at 1 site in India.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in India. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Active Knee Extension Test (time frame: From enrollment to the end of treatment at 1 week). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2025.