Neovascular GlaucomaNCT07177807
Clinical Characteristics of Neovascular Glaucoma
An observational study of Neovascular Glaucoma, run by Zhongnan Hospital at 1 site in China.
Trial summary
The goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Neovascular Glaucoma
- How many people
- 400 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2018to 1 Sep 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patients with NVG diagnosed by ophthalmic examination in the Second Clinical Hospital of Wuhan University, Central Hospital of Enshi Tujia and Miao Autonomous Prefecturefrom and Central Hospital of Xiaogan from January 2018 to September 2024 were enrolled. A certain number of healthy volunteers in the Physical Examination Center of the Second Clinical Hospital of Wuhan University from January 2018 to September 2024 were enrolled
Who may be able to join
- Patients who met the diagnostic criteria for NVG.
Who cannot join
- Patients with incomplete clinical data and information.
- Severe systemic diseases (such as chronic renal failure requiring dialysis, severe neurological diseases, immune diseases), pregnancy or lactation.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Clinical Characteristics of Neovascular Glaucoma : A Six-Year Retrospective Study
The goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. To systematically analyze the clinical data of NVG patients with different types of primary disease, further reveal the different clinical characteristics of NVG patients with different primary disease, and describe the selection of treatment methods in recent years, in order to provide more scientific basis for clinical treatment.
Read the detailed description
The goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. To systematically analyze the clinical data of NVG patients with different types of primary disease, further reveal the different clinical characteristics of NVG patients with different primary disease, and describe the selection of treatment methods in recent years, in order to provide more scientific basis for clinical treatment.Patients discharged from multiple hospitals from January 2018 to September 2024 with the diagnosis of NVG were retrospectively investigated. The medical history of each patient was reviewed, and the basic information, past medical history, eye examinations and their results, treatment plans, and prognosis information of the patients were recorded in detail.
- Conditions
- Neovascular Glaucoma
- Keywords
- Neovascular glaucoma, clinical feature, Retinal Vein Occlusion, Diabetic Retinopathy
- Medical subject headings
- Glaucoma, Neovascular, Retinal Vein Occlusion, Diabetic Retinopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| ALL group | Not described | |
| DR group | Not described | |
| RVO group | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
visual acuity
best-corrected visual acuity （BCVA）
Measured: Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.
intraocular pressure
intraocular pressure(IOP)
Measured: Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Sep 2025
- Study start1 Jan 2018
- Primary completion1 Sep 2024
- Study completion1 Sep 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neovascular GlaucomaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 400 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zhongnan Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture, Central Hospital of Xiaogan
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07177807
- Sponsor's protocol ID
- 20250719
- Status last verified
- Sep 2025
- First submitted
- 10 Sep 2025
- Last updated
- 17 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Characteristics of Neovascular Glaucoma : A Six-Year Retrospective Study
- ClinicalTrials.gov ID
- NCT07177807
- Acronym / sponsor ID
- 20250719
- Conditions
- Neovascular Glaucoma
- Keywords
- Neovascular glaucoma, clinical feature, Retinal Vein Occlusion, Diabetic Retinopathy
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 400 participants (actual)
- Lead sponsor
- Zhongnan HospitalUniversity, hospital or other
- Collaborators
- The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture, Central Hospital of Xiaogan
- Study start
- 1 Jan 2018 (actual)
- Primary completion
- 1 Sep 2024 (actual)
- Study completion
- 1 Sep 2024 (actual)
- First posted
- 17 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. To systematically analyze the clinical data of NVG patients with different types of primary disease, further reveal the different clinical characteristics of NVG patients with different primary disease, and describe the selection of treatment methods in recent years, in order to provide more scientific basis for clinical treatment.
Detailed description
The goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. To systematically analyze the clinical data of NVG patients with different types of primary disease, further reveal the different clinical characteristics of NVG patients with different primary disease, and describe the selection of treatment methods in recent years, in order to provide more scientific basis for clinical treatment.Patients discharged from multiple hospitals from January 2018 to September 2024 with the diagnosis of NVG were retrospectively investigated. The medical history of each patient was reviewed, and the basic information, past medical history, eye examinations and their results, treatment plans, and prognosis information of the patients were recorded in detail.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| ALL group | – | – |
| DR group | – | – |
| RVO group | – | – |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients with NVG diagnosed by ophthalmic examination in the Second Clinical Hospital of Wuhan University, Central Hospital of Enshi Tujia and Miao Autonomous Prefecturefrom and Central Hospital of Xiaogan from January 2018 to September 2024 were enrolled. A certain number of healthy volunteers in the Physical Examination Center of the Second Clinical Hospital of Wuhan University from January 2018 to September 2024 were enrolled
Key inclusion criteria (1 listed)
- Patients who met the diagnostic criteria for NVG.
Key exclusion criteria (2 listed)
- Patients with incomplete clinical data and information.
- Severe systemic diseases (such as chronic renal failure requiring dialysis, severe neurological diseases, immune diseases), pregnancy or lactation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
visual acuity
Time frame: Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.
best-corrected visual acuity （BCVA）
intraocular pressure
Time frame: Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.
intraocular pressure(IOP)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Neovascular Glaucoma, run by Zhongnan Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
visual acuity (time frame: Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2025.