Ultrasound-Guided Vascular AccessNCT07062068
Ultrasound-Guided BCV and IJV in ICU Patients
A study testing ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients in people with Ultrasound-Guided Vascular Access and ICU Patients, run by Sohag University.
Trial summary
This is a prospective randomized clinical trial aiming to compare the success rate, complications, and insertion time between ultrasound-guided brachiocephalic vein (BCV) and internal jugular vein (IJV) cannulation in mechanically ventilated patients in the intensive care unit (ICU). Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Ultrasound-Guided Vascular Access, ICU Patients
- What is being tested?
- ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- No sites listed yet
- Study dates
- Jul 2025to Dec 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- 100 patients with age between ( 18 - 50 years old ) ventilated in ICU with need central venous access , with physical status II or III according to ASA classification .
Who cannot join
- refusal of relatives of patients
- Any contraindication of Central venous line insertion as thrombocytopenia , coagulopathy …. Etc
- any suspected or documented thrombus inside vein
- any congenital or acquired musculo-skeletal deformities of neck or clavicle
- any active infections or signs of inflammation over insertion site
- any previous procedures performed at the cannulation site
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Comparative Study Between Ultrasound-Guided Brachiocephalic Vein and Internal Jugular Vein Cannulation in Mechanically Ventilated ICU Patients
This is a prospective randomized clinical trial aiming to compare the success rate, complications, and insertion time between ultrasound-guided brachiocephalic vein (BCV) and internal jugular vein (IJV) cannulation in mechanically ventilated patients in the intensive care unit (ICU). The goal is to determine whether BCV access offers a safer or more effective alternative in critically ill patients requiring central venous catheter placement.
Read the detailed description
Central venous cannulation is a common and essential procedure in the management of critically ill patients, especially those requiring mechanical ventilation. Traditionally, the internal jugular vein (IJV) has been the preferred site. However, the brachiocephalic vein (BCV) has recently gained attention due to its potentially favorable anatomical location and reduced complication rates.
This study is designed to compare the outcomes of ultrasound-guided cannulation of the BCV versus the IJV, focusing on parameters such as success rate of insertion on first attempt, total cannulation time, and incidence of complications such as arterial puncture, pneumothorax, or hematoma formation. The study will be conducted on adult patients admitted to the ICU and undergoing mechanical ventilation
- Conditions
- Ultrasound-Guided Vascular Access, ICU Patients
- Being tested
- ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients
- Keywords
- Comparative Study Between Ultrasound-Guided Brachiocephalic Vein and Internal Jugular Vein Cannulation in Mechanically Ventilated ICU Patients
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patientsProcedure or surgery
For Arm ( candidates for BCV cannulation ) :
by ultrasound guided we insert Central venous catheter in BCV under complete aseptic condition For Arm ( candidates for IJV cannulation ) by ultrasound guided we insert central venous catheter in IJV under complete aseptic conidtion we do comparison between the 2 arms as regard : 1st pass success rate , complications and failure rate in ventilated patient in ICU .
| Study group | Role | What they receive |
|---|---|---|
| candidates for BCV cannulation | Active comparator | Not described Receives: Procedure: ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients |
| candidates for IJV cannulation | Active comparator | Not described Receives: Procedure: ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients |
What is being measured
The primary outcome is the main question the study is designed to answer.
cannulation failure rate
Failure to cannulate selected vein at 1st attempt
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2025
- Study startJul 2025 (estimated)
- Primary completionNov 2025 (estimated)
- Study completionDec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ultrasound-Guided Vascular AccessStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hasnaa Mohy Ibrhim, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07062068
- Sponsor's protocol ID
- SU-BCV-IJV-2025
- Status last verified
- Jul 2025
- First submitted
- 2 Jul 2025
- Last updated
- 14 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 14 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Study Between Ultrasound-Guided Brachiocephalic Vein and Internal Jugular Vein Cannulation in Mechanically Ventilated ICU Patients
- ClinicalTrials.gov ID
- NCT07062068
- Acronym / sponsor ID
- SU-BCV-IJV-2025
- Conditions
- Ultrasound-Guided Vascular Access, ICU Patients
- Keywords
- Comparative Study Between Ultrasound-Guided Brachiocephalic Vein and Internal Jugular Vein Cannulation in Mechanically Ventilated ICU Patients
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- Jul 2025 (estimated)
- Primary completion
- Nov 2025 (estimated)
- Study completion
- Dec 2025 (estimated)
- First posted
- 14 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a prospective randomized clinical trial aiming to compare the success rate, complications, and insertion time between ultrasound-guided brachiocephalic vein (BCV) and internal jugular vein (IJV) cannulation in mechanically ventilated patients in the intensive care unit (ICU). The goal is to determine whether BCV access offers a safer or more effective alternative in critically ill patients requiring central venous catheter placement.
Detailed description
Central venous cannulation is a common and essential procedure in the management of critically ill patients, especially those requiring mechanical ventilation. Traditionally, the internal jugular vein (IJV) has been the preferred site. However, the brachiocephalic vein (BCV) has recently gained attention due to its potentially favorable anatomical location and reduced complication rates.
This study is designed to compare the outcomes of ultrasound-guided cannulation of the BCV versus the IJV, focusing on parameters such as success rate of insertion on first attempt, total cannulation time, and incidence of complications such as arterial puncture, pneumothorax, or hematoma formation. The study will be conducted on adult patients admitted to the ICU and undergoing mechanical ventilation
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| candidates for BCV cannulation | Active comparator | Procedure: ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients |
| candidates for IJV cannulation | Active comparator | Procedure: ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- 100 patients with age between ( 18 - 50 years old ) ventilated in ICU with need central venous access , with physical status II or III according to ASA classification .
Key exclusion criteria (6 listed)
- refusal of relatives of patients
- Any contraindication of Central venous line insertion as thrombocytopenia , coagulopathy …. Etc
- any suspected or documented thrombus inside vein
- any congenital or acquired musculo-skeletal deformities of neck or clavicle
- any active infections or signs of inflammation over insertion site
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patientsFor Arm ( candidates for BCV cannulation ) : by ultrasound guided we insert Central venous catheter in BCV under complete aseptic condition For Arm ( candidates for IJV cannulation ) by ultrasound guided we insert central venous catheter in IJV under complete aseptic conidtion we do comparison between the 2 arms as regard : 1st pass success rate , complications and failure rate in ventilated patient in ICU . | Procedure or surgery | candidates for BCV cannulation, candidates for IJV cannulation |
Primary outcome
cannulation failure rate
Time frame: Baseline
Failure to cannulate selected vein at 1st attempt
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jul 2025.
- Individual participant dataSharing planned: Undecided
Related trials for Ultrasound-Guided Vascular Access
Enrolling by invitation
TruVascular Access - Ultrasound-Guided Vascular Access Study
Peripheral Venous Catheterization, Difficult Intravenous Access
Recruiting
Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses
Difficult Vein Access, Emergency Department Patients
Active, not recruiting
Biplanar Handheld Ultrasound for Transradial Artery Puncture
Radial Artery Cannulation
Recruiting
Evaluating the Role of the Guidewire in Peripheral Intravenous Access: A Randomized Controlled Trial of Ultrasound-Guided Catheter Survival
Peripheral Intravenous Vein Catheter Phlebitis, Intravenous Infection
Recruiting
FEMART-1 Pilot Study
Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients in people with Ultrasound-Guided Vascular Access and ICU Patients, run by Sohag University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hasnaa mohey ibrahim, resident doctor (0201156950052, hasnaa.mohy@med.sohag.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
cannulation failure rate (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jul 2025.