Sudden Cardiac ArrestFEMART-1NCT07596446
FEMART-1 Pilot Study
A study testing Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement in people with Sudden Cardiac Arrest and Out-of-hospital Cardiac Arrest (OHCA), run by Emergency Medical Service, Prague at 1 site in Czechia.
Trial summary
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during ongoing cardiopulmonary resuscitation and after return of spontaneous circulation (ROSC). Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA), Cardiogenic Shock Acute
- What is being tested?
- Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteCzechia
- Study dates
- 11 May 2026to 30 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Non-traumatic out-of-hospital cardiac arrest (OHCA).
- Patients meeting criteria for one of the following clinical scenarios:
- Group A - ECPR-like group:
- Refractory cardiac arrest, including cardiac arrest occurring in the presence of the EMS crew.
- Age 18-70 years.
- Effective bystander cardiopulmonary resuscitation.
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- Initial rhythm of ventricular fibrillation (VF), pulseless ventricular tachycardia (pVT), or pulseless electrical activity (PEA).
- Group B - post-ROSC group:
- Return of spontaneous circulation (ROSC) after non-traumatic OHCA.
- Age 18-70 years.
Who cannot join
- Trauma as the probable primary cause of cardiac arrest.
- Known severe comorbidity, including:
- terminal stage of incurable disease (advanced malignancy, advanced dementia, terminal pulmonary disease, terminal heart failure, or palliative care status),
- established do-not-resuscitate (DNR) status,
- severe pre-existing neurological disability (CPC 3 or CPC 4),
- known severe peripheral arterial disease or known occlusion of lower limb arteries,
Show all 10Show fewer
- suspected pulmonary embolism with indication for thrombolytic therapy,
- known severe hematological disease associated with severe thrombocytopenia,
- morbid obesity.
- Known or suspected pregnancy.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Czechia1 site, 1 recruiting
- Recruiting
EMS Prague
Prague, 10100
Jan Spicak, MD, +420776155836, jan.spicak@zzshmp.cz
Silvie Trhlikova, MD PhD, +420607610869, silvie.trhlikova@zzshmp.cz
About this study
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during ongoing cardiopulmonary resuscitation and after return of spontaneous circulation (ROSC).
The primary objective of the study is to enable invasive arterial blood pressure monitoring for targeted and continuous hemodynamic management using vasopressor therapy in the prehospital setting. The study evaluates the feasibility, safety, and procedural performance of invasive arterial monitoring with the aim of improving assessment of the patient's hemodynamic status and enabling more accurate titration of vasopressor support. This approach may reduce episodes of hypotension and decrease the risk of recurrent cardiac arrest while allowing safer transport to specialized cardiac arrest centers.
Read more
Femoral arterial access enables more precise monitoring of perfusion pressure, targeted vasopressor titration, and early recognition of impending circulatory collapse. The intervention may contribute to improved early organ perfusion and could be associated with more favorable neurological and overall clinical outcomes after cardiac arrest. In accordance with the ERC Guidelines 2025, which emphasize active hemodynamic optimization after ROSC and acknowledge the potential role of invasive arterial pressure monitoring during ongoing resuscitation, the study evaluates not only feasibility, safety, and procedural timing, but also the potential clinical benefit of continuous hemodynamic-guided management in the prehospital phase, including (1) early identification of hypotension, (2) targeted vasopressor administration, and (3) prevention of re-arrest.
The study is conducted by the Prague Air Rescue Service Kryštof 01 (Prague Emergency Medical Services) in collaboration with the Central Bohemian Emergency Medical Service, the Second Department of Internal Medicine - Cardiology and Angiology of the General University Hospital in Prague and First Faculty of Medicine, Charles University, and the Department of Anesthesiology, Resuscitation and Intensive Care Medicine of the General University Hospital in Prague and First Faculty of Medicine, Charles University.
FEMART-1 is designed as a prospective pilot study without external funding.
- Being tested
- Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement
- Keywords
- ECPR, Femoral Arterial Sheath, Femoral Cannulation, Invasive Blood Pressure Monitoring, Prehospital Care, Emergency Medical Services, Resuscitation, Ultrasound-Guided Vascular Access, OHCA, ROSC, Hemodynamic Monitoring, Refractory Cardiac Arrest, ALS
- Medical subject headings
- Death, Sudden, Cardiac, Out-of-Hospital Cardiac Arrest, Heart Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Prehospital Ultrasound-Guided Femoral Arterial Sheath PlacementProcedure or surgery
Also called Femoral Arterial Cannulation, Prehospital Arterial Access, Femoral Arterial Sheath Insertion, Ultrasound-Guided Femoral Access
Ultrasound-guided placement of a femoral arterial sheath in the prehospital setting during ongoing cardiopulmonary resuscitation or after return of spontaneous circulation. The procedure is performed to enable invasive arterial blood pressure monitoring, optimization of hemodynamic management during ongoing cardiopulmonary resuscitation or post-resuscitation care, prevention of re-arrest, and to facilitate rapid transition to potential VA-ECMO cannulation if clinically indicated.
| Study group | Role | What they receive |
|---|---|---|
| Prehospital Femoral Arterial Sheath Insertion | Active comparator | Patients receive standard advanced prehospital resuscitation and post-resuscitation care including ultrasound-guided femoral arterial sheath insertion for invasive blood pressure monitoring and potential facilitation of subsequent VA-ECMO cannulation if clinically indicated. Receives: Procedure: Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement |
| Standard Prehospital Care | No intervention | Patients receive standard advanced prehospital resuscitation and post-resuscitation care without prehospital femoral arterial sheath insertion. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Percentage of Patients With Successful and Functional Invasive Arterial Blood Pressure Monitoring
Feasibility of prehospital femoral arterial sheath placement expressed as the percentage of patients with successfully established and functional invasive arterial blood pressure monitoring among patients in whom prehospital femoral arterial sheath placement was attempted following a clinical decision to perform the procedure.
Measured: During prehospital care until hospital arrival
Percentage of Patients With Major Procedure-Related Complications
Safety of prehospital femoral arterial sheath placement expressed as the percentage of patients with major procedure-related complications among patients in whom prehospital femoral arterial sheath placement was attempted following a clinical decision to perform the procedure. Major complications include clinically significant bleeding, vascular injury, distal limb ischemia, or sheath-related complications requiring therapeutic intervention.
Measured: From sheath insertion until hospital admission
Procedural Time Characteristics of Prehospital Femoral Arterial Sheath Placement
Assessment of procedural time characteristics of prehospital femoral arterial sheath placement among patients in whom the procedure was attempted following a clinical decision to perform the intervention. Time intervals are assessed using predefined procedural time points recorded during the intervention.
Measured: During prehospital care until hospital arrival
Secondary outcomes (8)
Use of Vasopressor or Inotropic Therapy in the Prehospital Setting
Comparison of the number and proportion of patients receiving vasopressor or inotropic therapy during prehospital care.
Measured: During prehospital care until hospital arrival
Recognition of Impending Hemodynamic Collapse After ROSC
Comparison of the number and proportion of patients with return of spontaneous circulation who develop hypotension (MAP below 50 mmHg) associated with re-initiation of cardiopulmonary resuscitation, initiation of vasopressor therapy, or escalation of ongoing vasopressor therapy during prehospital care.
Measured: During prehospital care until hospital arrival
Prehospital Re-arrest Rate
Comparison of the number and proportion of patients requiring defibrillation or manual/mechanical cardiopulmonary resuscitation after previously achieved return of spontaneous circulation during prehospital care.
Measured: During prehospital care until hospital arrival
In-Hospital Re-arrest Within 20 Minutes After Handover
Comparison of the number and proportion of patients transferred to the receiving hospital with return of spontaneous circulation who subsequently require defibrillation or manual/mechanical cardiopulmonary resuscitation within 20 minutes after hospital handover.
Measured: Within 20 minutes after hospital admission
Adequate Mean Arterial Pressure at Hospital Handover
Comparison of the number and proportion of patients with mean arterial pressure above 60 mmHg at hospital handover.
Measured: At hospital admission
Blood Lactate Level at Hospital Admission
Comparison of median and mean lactate levels measured at hospital admission.
Measured: At hospital admission
Heart Rate at Hospital Admission
Comparison of median and mean heart rate measured at hospital admission.
Measured: At hospital admission
Survival and Neurological Clinical Outcomes
Comparison of the number and percentage of patients surviving to hospital discharge, surviving with favorable neurological outcome defined as Cerebral Performance Category (CPC) 1-2 at hospital discharge, and surviving 30 days after the index event.
Measured: Through hospital discharge (up to 30 days) and at 30 days after the index event
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study start11 May 2026 (estimated)
- Primary completion31 Dec 2026 (estimated)
- Study completion30 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Sudden Cardiac ArrestStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- FEMART-1 is a prospective observational pilot study focused exclusively on non-traumatic out-of-hospital cardiac arrest (OHCA). The study compares two parallel prehospital management strategies: an invasive strategy including ultrasound-guided femoral arterial sheath placement and a standard non-invasive strategy. Allocation is non-randomized and organizationally determined according to the availability of a trained investigator qualified to perform the procedure. Patients are categorized into two clinical scenarios: (A) refractory cardiac arrest with consideration for ECPR ("ECPR-like" group) and (B) post-ROSC patients after OHCA. Post hoc exploratory stratification according to clinical scenario and management strategy creates four analytical subgroups (1A, 1B, 2A, 2B) for pilot data evaluation and future FEMART-2 trial planning. The study will continue until at least 20 patients are enrolled in the invasive arm.
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Emergency Medical Service, Prague
- Sponsor type
- Other government
- Collaborators
- General University Hospital, Prague, Emergency Medical Service of the Central Bohemian Region, Czech Republic
- Responsible party
- Sponsor
- Investigators
- Jan Spicak, MD, Principal investigator, Prague Emergency Medical Services
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07596446
- Sponsor's protocol ID
- ZZSHMP_001_2026
- Acronym
- FEMART-1
- Status last verified
- May 2026
- First submitted
- 7 May 2026
- Last updated
- 20 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Individual participant data sharing has not yet been determined. Future data sharing decisions will depend on data protection requirements, institutional policies, ethical considerations, and the feasibility of adequate anonymization of prehospital and hospital clinical data.
Publications
Ule J, Huppe T, Thiel J, Berwanger U, Schlechtriemen T, Conrad D, Merscher B. Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients-a prospective observational first year analysis. Scand J Trauma Resusc Emerg Med. 2025 Sep 2;33(1):145. doi: 10.1186/s13049-025-01461-9.
PubMed 40898249Butterfield ED, Price J, Bonsano M, Lachowycz K, Starr Z, Edmunds C, Barratt J, Major R, Rees P, Barnard EBG. Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service- a retrospective observational review of practice. Scand J Trauma Resusc Emerg Med. 2024 Mar 12;32(1):20. doi: 10.1186/s13049-024-01193-2.
PubMed 38475832Wildner G, Pauker N, Archan S, Gemes G, Rigaud M, Pocivalnik M, Prause G. Arterial line in prehospital emergency settings - A feasibility study in four physician-staffed emergency medical systems. Resuscitation. 2011 Sep;82(9):1198-201. doi: 10.1016/j.resuscitation.2011.05.002. Epub 2011 May 11.
PubMed 21621893
Study at a glance
From the registry record, last updated by the sponsor on 20 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- FEMART-1 Pilot Study
- ClinicalTrials.gov ID
- NCT07596446
- Acronym / sponsor ID
- FEMART-1 / ZZSHMP_001_2026
- Keywords
- ECPR, Femoral Arterial Sheath, Femoral Cannulation, Invasive Blood Pressure Monitoring, Prehospital Care, Emergency Medical Services, Resuscitation, Ultrasound-Guided Vascular Access
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Emergency Medical Service, PragueOther government
- Collaborators
- General University Hospital, Prague, Emergency Medical Service of the Central Bohemian Region, Czech Republic
- Study start
- 11 May 2026 (estimated)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 30 Mar 2027 (estimated)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during ongoing cardiopulmonary resuscitation and after return of spontaneous circulation (ROSC).
The primary objective of the study is to enable invasive arterial blood pressure monitoring for targeted and continuous hemodynamic management using vasopressor therapy in the prehospital setting. The study evaluates the feasibility, safety, and procedural performance of invasive arterial monitoring with the aim of improving assessment of the patient's hemodynamic status and enabling more accurate titration of vasopressor support. This approach may reduce episodes of hypotension and decrease the risk of recurrent cardiac arrest while allowing safer transport to specialized cardiac arrest centers.
Femoral arterial access enables more precise monitoring of perfusion pressure, targeted vasopressor titration, and early recognition of impending circulatory collapse. The intervention may contribute to improved early organ perfusion and could be associated with more favorable neurological and overall clinical outcomes after cardiac arrest. In accordance with the ERC Guidelines 2025, which emphasize active hemodynamic optimization after ROSC and acknowledge the potential role of invasive arterial pressure monitoring during ongoing resuscitation, the study evaluates not only feasibility, safety, and procedural timing, but also the potential clinical benefit of continuous hemodynamic-guided management in the prehospital phase, including (1) early identification of hypotension, (2) targeted vasopressor administration, and (3) prevention of re-arrest.
The study is conducted by the Prague Air Rescue Service Kryštof 01 (Prague Emergency Medical Services) in collaboration with the Central Bohemian Emergency Medical Service, the Second Department of Internal Medicine - Cardiology and Angiology of the General University Hospital in Prague and First Faculty of Medicine, Charles University, and the Department of Anesthesiology, Resuscitation and Intensive Care Medicine of the General University Hospital in Prague and First Faculty of Medicine, Charles University.
FEMART-1 is designed as a prospective pilot study without external funding.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- FEMART-1 is a prospective observational pilot study focused exclusively on non-traumatic out-of-hospital cardiac arrest (OHCA). The study compares two parallel prehospital management strategies: an invasive strategy including ultrasound-guided femoral arterial sheath placement and a standard non-invasive strategy. Allocation is non-randomized and organizationally determined according to the availability of a trained investigator qualified to perform the procedure. Patients are categorized into two clinical scenarios: (A) refractory cardiac arrest with consideration for ECPR ("ECPR-like" group) and (B) post-ROSC patients after OHCA. Post hoc exploratory stratification according to clinical scenario and management strategy creates four analytical subgroups (1A, 1B, 2A, 2B) for pilot data evaluation and future FEMART-2 trial planning. The study will continue until at least 20 patients are enrolled in the invasive arm.
| Arm | Type | Receives |
|---|---|---|
| Prehospital Femoral Arterial Sheath Insertion | Active comparator | Procedure: Prehospital Ultrasound-Guided Femoral Arterial Sheath PlacementPatients receive standard advanced prehospital resuscitation and post-resuscitation care including ultrasound-guided femoral arterial sheath insertion for invasive blood pressure monitoring and potential facilitation of subsequent VA-ECMO cannulation if clinically indicated. |
| Standard Prehospital Care | No intervention | –Patients receive standard advanced prehospital resuscitation and post-resuscitation care without prehospital femoral arterial sheath insertion. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (10 listed)
- Non-traumatic out-of-hospital cardiac arrest (OHCA).
- Refractory cardiac arrest, including cardiac arrest occurring in the presence of the EMS crew.
- Age 18-70 years.
- Effective bystander cardiopulmonary resuscitation.
- Initial rhythm of ventricular fibrillation (VF), pulseless ventricular tachycardia (pVT), or pulseless electrical activity (PEA).
Key exclusion criteria (10 listed)
- Trauma as the probable primary cause of cardiac arrest.
- Known severe comorbidity, including:
- Known or suspected pregnancy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Prehospital Ultrasound-Guided Femoral Arterial Sheath PlacementAlso: Femoral Arterial Cannulation, Prehospital Arterial Access, Femoral Arterial Sheath Insertion, Ultrasound-Guided Femoral AccessUltrasound-guided placement of a femoral arterial sheath in the prehospital setting during ongoing cardiopulmonary resuscitation or after return of spontaneous circulation. The procedure is performed to enable invasive arterial blood pressure monitoring, optimization of hemodynamic management during ongoing cardiopulmonary resuscitation or post-resuscitation care, prevention of re-arrest, and to facilitate rapid transition to potential VA-ECMO cannulation if clinically indicated. | Procedure or surgery | Prehospital Femoral Arterial Sheath Insertion |
Primary outcome
Percentage of Patients With Successful and Functional Invasive Arterial Blood Pressure Monitoring
Time frame: During prehospital care until hospital arrival
Feasibility of prehospital femoral arterial sheath placement expressed as the percentage of patients with successfully established and functional invasive arterial blood pressure monitoring among patients in whom prehospital femoral arterial sheath placement was attempted following a clinical decision to perform the procedure.
Percentage of Patients With Major Procedure-Related Complications
Time frame: From sheath insertion until hospital admission
Safety of prehospital femoral arterial sheath placement expressed as the percentage of patients with major procedure-related complications among patients in whom prehospital femoral arterial sheath placement was attempted following a clinical decision to perform the procedure. Major complications include clinically significant bleeding, vascular injury, distal limb ischemia, or sheath-related complications requiring therapeutic intervention.
Procedural Time Characteristics of Prehospital Femoral Arterial Sheath Placement
Time frame: During prehospital care until hospital arrival
Assessment of procedural time characteristics of prehospital femoral arterial sheath placement among patients in whom the procedure was attempted following a clinical decision to perform the intervention. Time intervals are assessed using predefined procedural time points recorded during the intervention.
8 secondary outcomes
Use of Vasopressor or Inotropic Therapy in the Prehospital Setting
Time frame: During prehospital care until hospital arrival
Recognition of Impending Hemodynamic Collapse After ROSC
Time frame: During prehospital care until hospital arrival
Prehospital Re-arrest Rate
Time frame: During prehospital care until hospital arrival
In-Hospital Re-arrest Within 20 Minutes After Handover
Time frame: Within 20 minutes after hospital admission
Adequate Mean Arterial Pressure at Hospital Handover
Time frame: At hospital admission
Blood Lactate Level at Hospital Admission
Time frame: At hospital admission
Heart Rate at Hospital Admission
Time frame: At hospital admission
Survival and Neurological Clinical Outcomes
Time frame: Through hospital discharge (up to 30 days) and at 30 days after the index event
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 May 2026.
- Background: PubMed 40898249Ule J, Huppe T, Thiel J, Berwanger U, Schlechtriemen T, Conrad D, Merscher B. Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients-a prospective observational first year analysis. Scand J Trauma Resusc Emerg Med. 2025 Sep 2;33(1):145. doi: 10.1186/s13049-025-01461-9.
- Background: PubMed 38475832Butterfield ED, Price J, Bonsano M, Lachowycz K, Starr Z, Edmunds C, Barratt J, Major R, Rees P, Barnard EBG. Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service- a retrospective observational review of practice. Scand J Trauma Resusc Emerg Med. 2024 Mar 12;32(1):20. doi: 10.1186/s13049-024-01193-2.
- Background: PubMed 21621893Wildner G, Pauker N, Archan S, Gemes G, Rigaud M, Pocivalnik M, Prause G. Arterial line in prehospital emergency settings - A feasibility study in four physician-staffed emergency medical systems. Resuscitation. 2011 Sep;82(9):1198-201. doi: 10.1016/j.resuscitation.2011.05.002. Epub 2011 May 11.
- Individual participant dataSharing planned: Undecided. Individual participant data sharing has not yet been determined. Future data sharing decisions will depend on data protection requirements, institutional policies, ethical considerations, and the feasibility of adequate anonymization of prehospital and hospital clinical data.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jan Spicak, MD principal investigator
Prague Emergency Medical Services
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement in people with Sudden Cardiac Arrest and Out-of-hospital Cardiac Arrest (OHCA), run by Emergency Medical Service, Prague at 1 site in Czechia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 20 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Czechia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jan Spicak, MD (00420776155836, jan.spicak@zzshmp.cz), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Percentage of Patients With Successful and Functional Invasive Arterial Blood Pressure Monitoring (time frame: During prehospital care until hospital arrival). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07596446, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 May 2026.