Out-of-hospital Cardiac Arrest (OHCA)NCT07042061
Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore.
A study testing Mobile external automated defibrillator in people with Out-of-hospital Cardiac Arrest (OHCA), run by Singapore General Hospital.
Trial summary
The goal of this clinical trial is to learn the feasibility of equipping the volunteer community responders (VCR) with the mobile external automated defibrillators (mAEDs) for the management of adults experiencing out-of-hospital cardiac arrest (OHCA) patients. Read more about this study
- Who is it for?
- Ages 21 to 74 years
- Conditions the study is for
- Out-of-hospital Cardiac Arrest (OHCA)
- What is being tested?
- Mobile external automated defibrillator
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,000 participants
- Where
- No sites listed yet
- Study dates
- 1 May 2026to 31 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 74 years
- All sexes
- No healthy volunteers
- Adult, Older adult
1.1. Inclusion Criteria
Study participants must meet all the inclusion criteria to participate in this study:
- Must be proficient in English. Able to read and understand English fluently.
- Be aged 21-74 years of age at point of recruitment.
- Willing and able to move rapidly to a scene that can be 400 meters away from their location.
- Be a registered CFR with SCDF.
- Must be active myResponder® mobile phone app user so they can receive alerts about nearby OHCA cases.
1.2. Exclusion Criteria All subjects meeting any of the following exclusion criteria will be excluded from participation in this study.
- Not proficient in English. Cannot read and understand English.
- Aged less than 21 and over 74 years of age.
- Not willing to be a myResponder app user.
- Not able to move rapidly to a scene that can be 400 meters away from their location.
- Given the short duration of the trial, those who are pregnant will be ineligible.
- Those experiencing any serious physical injury or handicap and those with obvious mental handicap.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Garion Senior Executive contact
About this study
Official title: Out-of-Hospital Cardiac Arrest Care Through Empowered and Equipped Community First Responders: Mobile External Defibrillation Investigation for Cardiac Arrest in Singapore (MEDICS).
The goal of this clinical trial is to learn the feasibility of equipping the volunteer community responders (VCR) with the mobile external automated defibrillators (mAEDs) for the management of adults experiencing out-of-hospital cardiac arrest (OHCA) patients. It will also provide early signals if this enhanced system can help increase the frequency of defibrillation and doing it earlier. The main questions it aims to answer are:
- Can equipped VCRs apply mAEDs more frequently and earlier to potentially get more patients successfully resuscitated?
- Is this system enhancement is feasible in the long run.
Read more
Participants, the VCRs, will:
- Carry a 450 gm mAED with them all the time for up to an year and use it on an OHCA patient if and when alerted to help.
- They will hand over this single-use battery-operated device to the EMS crew for data retrieval and potential replacement
- They will be interviewed for their experience of being equipped and use of the mAED.
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA)
- Being tested
- Mobile external automated defibrillator
- Keywords
- Out-of-hospital, Cardiac arrest, Automated external defibrillator, AED, Community volunteers
- Medical subject headings
- Out-of-Hospital Cardiac Arrest, Heart Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mobile external automated defibrillatorDevice
A single-use, hand-held, chocolate bar sized portable AED
| Study group | Role | What they receive |
|---|---|---|
| AED arm | Experimental | Not described Receives: Device: Mobile external automated defibrillator |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility of a full scale trial
A validated AIM/FIM tool will be used to collect perceptions of the users and managers using a likert scale measurement reporting on feasibility and acceptability of the intervention
Measured: Through study completion, an average of 1 year
Secondary outcomes (3)
Qualitative experiences of CFR elicited through semi-structured interviews
Experience of the CFRs as regards challenges faced while carrying the device and convenience when the device is needed
Measured: 1 year
Qualitative experiences of CFR elicited through semi-structured interviews
Experience of the CFRs as regards challenges of using the new device as compared to standard of care device
Measured: 1 year
Qualitative experiences of CFR elicited through semi-structured interviews
Responses of the patient's relatives regarding the use of the device by CFRs before and after the usage as perceived by the CFRs
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jun 2025
- Study start1 May 2026 (estimated)
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Out-of-hospital Cardiac Arrest (OHCA)Studies of the same condition, open and under way.
- More trials run by Singapore General HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Singapore General Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Singapore Civil Defence Force, Duke-NUS Graduate Medical School
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07042061
- Sponsor's protocol ID
- ECOS 2024-3485
- Status last verified
- Jun 2025
- First submitted
- 4 Jun 2025
- Last updated
- 27 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The trial include government owned information and hence cannot be released.
Publications
Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.
PubMed 28851459
Study at a glance
From the registry record, last updated by the sponsor on 27 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Out-of-Hospital Cardiac Arrest Care Through Empowered and Equipped Community First Responders: Mobile External Defibrillation Investigation for Cardiac Arrest in Singapore (MEDICS).
- ClinicalTrials.gov ID
- NCT07042061
- Acronym / sponsor ID
- ECOS 2024-3485
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA)
- Keywords
- Out-of-hospital, Cardiac arrest, Automated external defibrillator, AED, Community volunteers
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- Singapore General HospitalUniversity, hospital or other
- Collaborators
- Singapore Civil Defence Force, Duke-NUS Graduate Medical School
- Study start
- 1 May 2026 (estimated)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Jan 2027 (estimated)
- First posted
- 27 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn the feasibility of equipping the volunteer community responders (VCR) with the mobile external automated defibrillators (mAEDs) for the management of adults experiencing out-of-hospital cardiac arrest (OHCA) patients. It will also provide early signals if this enhanced system can help increase the frequency of defibrillation and doing it earlier. The main questions it aims to answer are:
- Can equipped VCRs apply mAEDs more frequently and earlier to potentially get more patients successfully resuscitated?
- Is this system enhancement is feasible in the long run.
Participants, the VCRs, will:
- Carry a 450 gm mAED with them all the time for up to an year and use it on an OHCA patient if and when alerted to help.
- They will hand over this single-use battery-operated device to the EMS crew for data retrieval and potential replacement
- They will be interviewed for their experience of being equipped and use of the mAED.
Study design
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| AED arm | Experimental | Device: Mobile external automated defibrillator |
Who may qualify
- Ages
- 21 to 74 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mobile external automated defibrillatorA single-use, hand-held, chocolate bar sized portable AED | Device | AED arm |
Primary outcome
Feasibility of a full scale trial
Time frame: Through study completion, an average of 1 year
A validated AIM/FIM tool will be used to collect perceptions of the users and managers using a likert scale measurement reporting on feasibility and acceptability of the intervention
3 secondary outcomes
Qualitative experiences of CFR elicited through semi-structured interviews
Time frame: 1 year
Qualitative experiences of CFR elicited through semi-structured interviews
Time frame: 1 year
Qualitative experiences of CFR elicited through semi-structured interviews
Time frame: 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Apr 2026.
- Background: PubMed 28851459Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.
- Individual participant dataSharing planned: No. The trial include government owned information and hence cannot be released.
Related trials for Out-of-hospital Cardiac Arrest (OHCA)
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Cardiac Arrest (CA)
Active, not recruitingObservational study
Frontal EEG in OHCA Feasibility Study
Out-Of-Hospital Cardiac Arrest, BIS
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Garion Senior Executive contact
Questions about this trial
What is this clinical trial studying?
A study testing Mobile external automated defibrillator in people with Out-of-hospital Cardiac Arrest (OHCA), run by Singapore General Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 27 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Fahad J Siddiqui (+65 66017951, fahad.siddiqui@duke-nus.edu.sg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility of a full scale trial (time frame: Through study completion, an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07042061, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2026.