Facial AsymmetryNCT07008807
The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry
An observational study of Facial Asymmetry, run by South Valley University at 1 site in Egypt.
Trial summary
Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. Read more about this study
- Who is it for?
- Ages 16 years and older
- Conditions the study is for
- Facial Asymmetry
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2025to 1 Aug 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Presenting with noticeable facial asymmetry.
Who may be able to join
- Presenting with noticeable facial asymmetry
- Age > 16 years
- General good health
- Absence of specific neurological conditions affecting facial muscles.
- Absence of congenital facial disorders that might cause facial asymmetry, like hemifacial microsomia and cleft lip and palate syndromes.
Who cannot join
- History of facial trauma or surgery
- Diagnosed Neuromuscular Disorders
- Active facial infections.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Nehad A. Abo-zaid, PhD contact
Egypt1 site
orthodontic outpatient clinic, and students at Faculty of Dentistry, Alsalam University, Egypt
Tanta, Tanta
Ayman Elmakakey, PhD, 01006740689, A.elmakaky@svu.edu.eg
About this study
Official title: The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry, A Prospective Correlation Study
Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.
- Conditions
- Facial Asymmetry
- Medical subject headings
- Facial Asymmetry
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| group A | people with facial asymmetry | |
| Group B | control group of healthy normal people |
What is being measured
The primary outcome is the main question the study is designed to answer.
Facial Electromyography (EMG)
Measured: Day 1
Facial Asymmetry Measurement
assesses differences between the two sides of the face using various techniques, both two-dimensional (2D) and three-dimensional (3D)
Measured: Day 1
Secondary outcomes (1)
Demographic and Clinical Data
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Jun 2025
- Study start1 Jun 2025 (estimated)
- Primary completion1 Jul 2025 (estimated)
- Study completion1 Aug 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Facial AsymmetryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- South Valley University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohammed E. Ali, South Valley University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07008807
- Sponsor's protocol ID
- SREC.PT.SUE(7)325
- Status last verified
- May 2025
- First submitted
- 20 May 2025
- Last updated
- 6 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
4. Kowner, R. (1996). Facial asymmetry and attractiveness judgment in Western and Japanese cultures. Journal of Social Behavior and Personality, 11(2), 301-314.
Ferrario VF, Dellavia C, Tartaglia GM, Turci M, Sforza C. Soft tissue facial morphology in obese adolescents: a three-dimensional noninvasive assessment. Angle Orthod. 2004 Feb;74(1):37-42. doi: 10.1043/0003-3219(2004)0742.0.CO;2.
PubMed 15038489
Study at a glance
From the registry record, last updated by the sponsor on 6 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry, A Prospective Correlation Study
- ClinicalTrials.gov ID
- NCT07008807
- Acronym / sponsor ID
- SREC.PT.SUE(7)325
- Conditions
- Facial Asymmetry
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- South Valley UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 1 Jul 2025 (estimated)
- Study completion
- 1 Aug 2025 (estimated)
- First posted
- 6 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| group A | – | –people with facial asymmetry |
| Group B | – | –control group of healthy normal people |
Who may qualify
- Ages
- 16 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Presenting with noticeable facial asymmetry.
Key inclusion criteria (5 listed)
- Presenting with noticeable facial asymmetry
- Age > 16 years
- General good health
- Absence of specific neurological conditions affecting facial muscles.
- Absence of congenital facial disorders that might cause facial asymmetry, like hemifacial microsomia and cleft lip and palate syndromes.
Key exclusion criteria (3 listed)
- History of facial trauma or surgery
- Diagnosed Neuromuscular Disorders
- Active facial infections.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Facial Electromyography (EMG)
Time frame: Day 1
Facial Asymmetry Measurement
Time frame: Day 1
assesses differences between the two sides of the face using various techniques, both two-dimensional (2D) and three-dimensional (3D)
1 secondary outcome
Demographic and Clinical Data
Time frame: Day 1
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Jun 2025.
- Background4. Kowner, R. (1996). Facial asymmetry and attractiveness judgment in Western and Japanese cultures. Journal of Social Behavior and Personality, 11(2), 301-314.
- Results publication: PubMed 15038489Ferrario VF, Dellavia C, Tartaglia GM, Turci M, Sforza C. Soft tissue facial morphology in obese adolescents: a three-dimensional noninvasive assessment. Angle Orthod. 2004 Feb;74(1):37-42. doi: 10.1043/0003-3219(2004)0742.0.CO;2.
- Individual participant dataSharing planned: Undecided
Related trials for Facial Asymmetry
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RecruitingPhase 4
Evaluation of Filler Injection for Chin Profile Enhancement
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Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.
Hemifacial Microsomia, Mucormycosis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nehad A. Abo-zaid, PhD contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Facial Asymmetry, run by South Valley University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 6 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mohammed E. Ali, PhD (+201011212425, m.essam@svu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Facial Electromyography (EMG) (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07008807, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Jun 2025.