OsteoarthritisCHAT-OANCT06778486

Conversations in Health Literacy Using AI Technology for Osteoarthritis Patients

A study testing Artificial Intelligence Chatbot in people with Osteoarthritis and Osteoarthritis of the Hip or Knee, run by University of California, Davis at 1 site in United States.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record

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Trial summary

The goal of this clinical trial is to assess the use of a generative artificial intelligence large language model chatbot in improving decision making factors in patients with hip and knee osteoarthritis. Read more about this study

Who is it for?: Ages 18 to 99 years
Conditions the study is for: Osteoarthritis, Osteoarthritis of the Hip or Knee
What is being tested?: Artificial Intelligence Chatbot
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 100 participants
Where: 1 siteUnited States
Study dates: 6 Jan 2025to Dec 2026
Phase: Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 99 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Adult
Ability to read and write in English
All races and ethnicities
Clinical symptoms of hip and/or knee osteoarthritis

Who cannot join

Inability to read and write in English

Trial locations and contacts

1 site in 1 country.

United States1 site

University of California Davis Health
Sacramento, California, 95817

Other trials in United States

About this study

Official title: CHAT-OA: Conversations in Health Literacy Using AI Technology for Osteoarthritis Patients

Does the use of an artificial intelligence chatbot have an effect on decisional conflict and anxiety related to decision making? Are changes in decisional conflict correlated with changes in patient reported outcomes? Are changes in decisional conflict correlated with health literacy? Participants will interact with an artificial intelligence chatbot prior to their clinic visit with an orthopaedic surgeon, using a structured prompt.

Conditions: Osteoarthritis, Osteoarthritis of the Hip or Knee
Being tested: Artificial Intelligence Chatbot
Keywords: artificial intelligence, health literacy, decisional conflict
Medical subject headings: Osteoarthritis, Osteoarthritis, Hip

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Artificial Intelligence ChatbotOther
The intervention is a generative artificial intelligence large language model chatbot that has a structured prompt with fill-in-the-blank style questions that the participant will complete.

Study groups in NCT06778486
Study group	Role	What they receive
Standard of care	No intervention	This arm will undergo standard clinical care without the intervention.
Artificial Intelligence Chatbot	Experimental	This arm will interact with an artificial intelligence chatbot prior to their clinic visit. Receives: Other: Artificial Intelligence Chatbot

What is being measured

The primary outcome is the main question the study is designed to answer.

Decisional Conflict Scale
16 questions with Likert scale style answers ranging from 0 to 4. The raw score is converted to a score out of 100. The score ranges from 0 (no decisional conflict) to 100 (extremely high decisional conflict).
Measured: At three time points: Within one week after the clinic visit, 1 month after the clinic visit, 6 months after the clinic visit.
Beck Anxiety Inventory
21 questions with Likert scale style answers ranging from 0 to 4. The raw score is the sum of the answers, which is converted to a score out of 100. The score ranges from 0 (low anxiety) to 63 (high anxiety).
Measured: At three time points: Within one week after the clinic visit, 1 month after the clinic visit, 6 months after the clinic visit.

Secondary outcomes (3)

Knee injury and Osteoarthritis Outcome Score for Joint Replacement
7 questions with Likert scale style answers ranging from 0 to 4. The raw score is the sum of the answers, which is converted to a score out of 100. The score ranges from 0 (total knee disability) to 100 (perfect knee health).
Measured: At enrollment
Hip dysfunction and Osteoarthritis Outcome Score for Joint Replacement
6 questions with Likert scale style answers ranging from 0 to 4. The raw score is the sum of the answers, which is converted to a score out of 100. The score ranges from 0 (total hip disability) to 100 (perfect hip health).
Measured: At enrollment
Patient-Reported Outcomes Measurement Information System Global Health Version 1.2
10 questions with Likert scale style answers ranging from 1 to 5 and 1 question about pain with answers from 0 to 10. The questions are grouped into 4 sub-groups corresponding to physical and mental health main groups, in addition to the pain score. The raw scores are a sum of the answers for both physical and mental health range from 4 (poor physical or mental health) to 20 (best possible physical or mental health). The raw score is then converted to a t-score using the associated tables with the range 16.2 (worst possible physical or mental health) to 67.7 (best possible physical or mental health). The t-score is interpreted in comparison to the general population that has a mean of 50 and standard deviation of 10.
Measured: At enrollment

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

6 Jan 2025Dec 2026

First posted16 Jan 2025
Study start6 Jan 2025
Primary completionDec 2026 (estimated)
Study completionDec 2026 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for OsteoarthritisStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Other
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 100 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT06778486
Sponsor's protocol ID: 2169004
Acronym: CHAT-OA
Status last verified: Sep 2026
First submitted: 22 Nov 2024
Last updated: 14 Sep 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

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