Anterior Glenoid Nerve BlockNCT06765278
Anterior Glenoid Nerve Block Versus Pericapsular Nerve Group Block Versus Interscalene Brachial Plexus Block for Postoperative Pain Management in Shoulder Arthroscopic Surgeries
A study testing Interscalene brachial plexus block, Anterior glenoid nerve block and Pericapsular nerve group block in people with Anterior Glenoid Nerve Block and Pericapsular Nerve Group Block, run by Ain Shams University at 1 site in Egypt.
Trial summary
This study aims to compare between Anterior glenoid nerve block, pericapsular nerve group (PENG) block and Interscalene brachial plexus (ISB) block for post-operative pain management in shoulder arthroscopic surgeries Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Anterior Glenoid Nerve Block, Pericapsular Nerve Group Block, Interscalene Brachial Plexus Block
- What is being tested?
- Interscalene brachial plexus block, Anterior glenoid nerve block and Pericapsular nerve group block
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 49 participants
- Where
- 1 siteEgypt
- Study dates
- 13 Jan 2025to 1 Jun 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age from 18 to 70 years.
- No sex predilection.
- American Society of Anesthesiology (ASA) physical status I-II.
- Undergoing shoulder arthroscopic surgeries.
Who cannot join
- Patient's refusal.
- Patients with a history of drug allergies to study drugs.
- Evidence of local infection at the site of injection.
- Inability to cooperate
- Neuromuscular pathology (example: - Multiple Sclerosis)
- Previous trauma or surgery to the shoulder
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Ain Shams University
Cairo, 11591
Mohamed Serry, Master, 00201002609476, mohamed.serry@med.asu.edu.eg
Amr E Abd El-Hamid, MD
About this study
Official title: Anterior Glenoid Nerve Block Versus Pericapsular Nerve Group (PENG) Block Versus Interscalene Brachial Plexus (ISB) Block for Postoperative Pain Management in Shoulder Arthroscopic Surgeries
This study aims to compare between Anterior glenoid nerve block, pericapsular nerve group (PENG) block and Interscalene brachial plexus (ISB) block for post-operative pain management in shoulder arthroscopic surgeries
Read the detailed description
Major surgeries of the shoulder constitute some of the most commonly performed orthopedic procedures. They often result in moderate to severe postoperative pain thereby requiring a multimodal analgesic approach centered around peripheral nerve blocks.
Postoperative pain management is the part of shoulder surgery to improve patient satisfaction, start rehabilitation process rapidly and decrease for hospital stay.
Interscalene blocks (ISB) are well-studied and established means of providing analgesia following shoulder surgery and are considered the gold standard mode of regional anesthesia and post-operative pain management in shoulder surgeries.
A novel technique: pericapsular nerve group (PENG) block can be effectively and safely applied under ultrasound guidance in shoulder surgery cases for postoperative analgesia. In addition, PENG block targets articular branches with less motor effect compared with interscalene brachial plexus block providing anesthetic and analgesic effect with less complication and better and sooner ambulation.
- Conditions
- Anterior Glenoid Nerve Block, Pericapsular Nerve Group Block, Interscalene Brachial Plexus Block, Postoperative Pain, Shoulder Arthroscopic Surgeries
- Being tested
- Interscalene brachial plexus block, Anterior glenoid nerve block, Pericapsular nerve group block
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Interscalene brachial plexus blockOther
Patients will receive an Interscalene brachial plexus block.
Anterior glenoid nerve blockOther
Patients will receive an anterior glenoid nerve block.
Pericapsular nerve group blockOther
Patients will receive a pericapsular nerve group (PENG) block.
| Study group | Role | What they receive |
|---|---|---|
| Interscalene brachial plexus block group | Active comparator | Patients will receive an Interscalene brachial plexus block. Receives: Other: Interscalene brachial plexus block |
| Anterior glenoid nerve block group | Experimental | Patients will receive an anterior glenoid nerve block. Receives: Other: Anterior glenoid nerve block |
| Pericapsular nerve group (PENG) block group | Experimental | Patients will receive a pericapsular nerve group (PENG) block. Receives: Other: Pericapsular nerve group block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Time to the 1st rescue analgesia
Time to the first request for the rescue analgesia (time from the end of surgery to the first dose of pethidine administrated).
Measured: 24 hours postoperatively
Secondary outcomes (5)
Total pethidine consumption
All patients will receive intravenous pethidine (30mg) on demand [Visual Analogue Scale (VAS) score ≥3].
Measured: 24 hours postoperatively
Degree of pain
Degree of pain will be assessed using visual analogue scale (VAS). Each patient will be instructed about postoperative pain assessment with the VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed at 0, 6, 12, and 24 hours postoperatively.
Measured: 24 hours postoperatively
Length of hospital stay
Length of hospital stay will be recorded from admission till the discharge from hospital.
Measured: Till discharge from hospital (Up to one week).
Time needed for the patient to freely move the operated limb
Time needed for the patient to freely move the operated limb will be recorded.
Measured: Postoperatively (Up to one week).
Degree of patients satisfaction
Degree of patient satisfaction will be assessed on a 5-point Likert scale patient satisfaction (1, extremely dissatisfied; 2, unsatisfied; 3, neutral; 4, satisfied; 5, extremely satisfied)
Measured: 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jan 2025
- Study start13 Jan 2025
- Primary completion1 Jun 2025 (estimated)
- Study completion1 Jun 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Glenoid Nerve BlockStudies of the same condition, open and under way.
- More trials run by Ain Shams UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 49 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ain Shams University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Serry, Ain Shams University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06765278
- Sponsor's protocol ID
- FMASU MD195/2024
- Status last verified
- Jan 2025
- First submitted
- 31 Dec 2024
- Last updated
- 14 Jan 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Study at a glance
From the registry record, last updated by the sponsor on 14 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Anterior Glenoid Nerve Block Versus Pericapsular Nerve Group (PENG) Block Versus Interscalene Brachial Plexus (ISB) Block for Postoperative Pain Management in Shoulder Arthroscopic Surgeries
- ClinicalTrials.gov ID
- NCT06765278
- Acronym / sponsor ID
- FMASU MD195/2024
- Conditions
- Anterior Glenoid Nerve Block, Pericapsular Nerve Group Block, Interscalene Brachial Plexus Block, Postoperative Pain, Shoulder Arthroscopic Surgeries
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 49 participants (estimated)
- Lead sponsor
- Ain Shams UniversityUniversity, hospital or other
- Study start
- 13 Jan 2025 (actual)
- Primary completion
- 1 Jun 2025 (estimated)
- Study completion
- 1 Jun 2025 (estimated)
- First posted
- 9 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare between Anterior glenoid nerve block, pericapsular nerve group (PENG) block and Interscalene brachial plexus (ISB) block for post-operative pain management in shoulder arthroscopic surgeries
Detailed description
Major surgeries of the shoulder constitute some of the most commonly performed orthopedic procedures. They often result in moderate to severe postoperative pain thereby requiring a multimodal analgesic approach centered around peripheral nerve blocks.
Postoperative pain management is the part of shoulder surgery to improve patient satisfaction, start rehabilitation process rapidly and decrease for hospital stay.
Interscalene blocks (ISB) are well-studied and established means of providing analgesia following shoulder surgery and are considered the gold standard mode of regional anesthesia and post-operative pain management in shoulder surgeries.
A novel technique: pericapsular nerve group (PENG) block can be effectively and safely applied under ultrasound guidance in shoulder surgery cases for postoperative analgesia. In addition, PENG block targets articular branches with less motor effect compared with interscalene brachial plexus block providing anesthetic and analgesic effect with less complication and better and sooner ambulation.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Interscalene brachial plexus block group | Active comparator | Other: Interscalene brachial plexus blockPatients will receive an Interscalene brachial plexus block. |
| Anterior glenoid nerve block group | Experimental | Other: Anterior glenoid nerve blockPatients will receive an anterior glenoid nerve block. |
| Pericapsular nerve group (PENG) block group | Experimental | Other: Pericapsular nerve group blockPatients will receive a pericapsular nerve group (PENG) block. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age from 18 to 70 years.
- No sex predilection.
- American Society of Anesthesiology (ASA) physical status I-II.
- Undergoing shoulder arthroscopic surgeries.
Key exclusion criteria (6 listed)
- Patient's refusal.
- Patients with a history of drug allergies to study drugs.
- Evidence of local infection at the site of injection.
- Inability to cooperate
- Neuromuscular pathology (example: - Multiple Sclerosis)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Interscalene brachial plexus blockPatients will receive an Interscalene brachial plexus block. | Other | Interscalene brachial plexus block group |
| Anterior glenoid nerve blockPatients will receive an anterior glenoid nerve block. | Other | Anterior glenoid nerve block group |
| Pericapsular nerve group blockPatients will receive a pericapsular nerve group (PENG) block. | Other | Pericapsular nerve group (PENG) block group |
Primary outcome
Time to the 1st rescue analgesia
Time frame: 24 hours postoperatively
Time to the first request for the rescue analgesia (time from the end of surgery to the first dose of pethidine administrated).
5 secondary outcomes
Total pethidine consumption
Time frame: 24 hours postoperatively
Degree of pain
Time frame: 24 hours postoperatively
Length of hospital stay
Time frame: Till discharge from hospital (Up to one week).
Time needed for the patient to freely move the operated limb
Time frame: Postoperatively (Up to one week).
Degree of patients satisfaction
Time frame: 24 hours postoperatively
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jan 2025.
- Individual participant dataSharing planned: Yes. The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Related trials for Anterior Glenoid Nerve Block
Recruiting
Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery
Interscalene Block, Suprascapular Nerve Block
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Interscalene brachial plexus block, Anterior glenoid nerve block and Pericapsular nerve group block in people with Anterior Glenoid Nerve Block and Pericapsular Nerve Group Block, run by Ain Shams University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 14 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mohamed Serry, Master (00201002609476, mohamed.serry@med.asu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time to the 1st rescue analgesia (time frame: 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jan 2025.