Research institution
Ain Shams University Clinical Trials
Studies where Ain Shams University is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 275Edentulous Complete Denture Wearers
Comparison of Conventional and Face Scan in Recording the Vertical Dimension of Completely Edentulous Patients
The purpose of this study is to evaluate if a 3D face scanner is a reliable and accurate tool for measuring the vertical dimension of occlusion (the optimal height of the lower face) in patients who have lost all their teeth.
- Trial name
- NCT07898332
- Testing
- Face scan
- Where
- 2 sites in Egypt
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Pulmonary Hypertension
Colchicine in Pulmonary Artery Hypertension Patients
This study evaluates the efficacy of colchicine in improving cardiopulmonary function for patients diagnosed with Pulmonary Arterial Hypertension (PAH), a condition characterized by elevated pulmonary pressure that impairs right…
- Trial name
- NCT07907757
- Testing
- Colchicine 0.5 MG Oral Tablet
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Developmental Dysplasia of the Hip, Acetabular Bone Loss
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Total hip arthroplasty (THA) in patients with complex acetabular anatomy can be challenging because of abnormal bone structure, deformity, or bone loss.
- Conditions
- Developmental Dysplasia of the Hip, Acetabular Bone Loss, Acetabular Fracture
- Trial name
- NCT07904637
- Testing
- Conventional Imaging-Based Preoperative Planning, CT-Based 3D-Printed Pelvic Model-Assisted Planning
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Pain Management, Parasternal Block
Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG
Influence of Superficial Parasternal Intercostal Plane Block (SPIPB) on Internal Thoracic Artery (ITA) Caliber and Surgical Harvesting Efficiency in Coronary Artery Bypass Grafting (CABG)
- Conditions
- Pain Management, Parasternal Block, CABG Graft Integrity
- Trial name
- IMA CABG PIPB (NCT07663435)
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Gummy Smile of Altered Passive Eruption Type 1B
Accuracy of Stackable Double Periodontal Guide in Esthetic Crown Lengthening
The goal of this clinical trial is to find out if a new digital surgical guide helps dentists perform esthetic crown lengthening more accurately than the current digital guide in adults with a gummy smile caused by altered…
- Trial name
- NCT07891598
- Testing
- Stackable double digital periodontal guide, Conventional double digital periodontal guide
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Congenital Peumonia, Persistent Pulmonary Hypertension of Newborn
Effect of Melatonin on Pulmonary Hypertension in Full Term Neonates
The aim of the study 1. To evaluate safety and efficacy of melatonin as an adjuvant therapy to inhaled nitric oxide generated by NO generator in the treatment of pulmonary hypertension in full term neonates. 2.
- Conditions
- Congenital Peumonia, Persistent Pulmonary Hypertension of Newborn, Congenital Diaphragmatic Hernia
- Trial name
- NCT07850934
- Testing
- Melatonin, nitric oxide generator
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
CPAP Ventilation, Sedation
Dexametedomidine Ketamine Infusion Versus Dexametedomidine Propofol Infusion in Non-compliant Agitated Patients on Continuous Positive Airway Pressure (CPAP) Mask Ventilation in the Intensive Care Unit
Continuous positive airway pressure (CPAP) is a type of positive airway pressure, where the air flow is introduced into the airways to maintain a continuous pressure to constantly stent the airways open, in people who are…
- Conditions
- CPAP Ventilation, Sedation, Hemodynamics Instability
- Trial name
- CPAP (NCT07888192)
- Testing
- Group DK will receive dexmedetomidine (0.2-1.4 μg/kg/hour) and ketamine (0.5 mg/kg/hr)., Group KP will receive dexmedetomidine (0.2-1.4 μg/kg/hour) and propofol (2-4 mg/kg/hr).(
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Endothelial Dysfunction, End-Stage Renal Disease
Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients
The goal of this clinical trial is to learn if Ramipril works better than Amlodipine to reduce endothelial dysfunction in pediatric patients (aged 5-18 years) with end-stage kidney disease undergoing maintenance hemodialysis and…
- Conditions
- Endothelial Dysfunction, End-Stage Renal Disease, Pediatric Kidney Disease
- Trial name
- ADMA /PedsQL (NCT07879560)
- Testing
- Ramipril tablet, Amlodipine tablet
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Partial Edentulism, Dental Implant
Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants
This randomized controlled trial compares immediate and conventional loading of single implants placed immediately into fresh extraction sockets in the upper front and premolar region.
- Conditions
- Partial Edentulism, Dental Implant, Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement
- Trial name
- NCT07882095
- Testing
- Conventional loading, Monolithic zirconia crown, Permanent 3D-printed PMMA crown
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Completed, with results posted
All 27Breast Neoplasm Female, Postoperative Pain Management
PECS II vs. MTP for Analgesia After MRM
This randomized controlled study aims to compare the analgesic efficacy of the ultrasound-guided modified pectoral nerve block (PECS II) and the midpoint transverse process to pleura (MTP) block in female patients undergoing…
- Trial name
- NCT06187909
- Testing
- PECS II BLOCK, MTP BLOCK
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Intra-Abdominal Infections, Intestinal Obstruction
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
In this study the investigators going to evaluate the "CLI" as an early prognostic indicator for post-operative abdominal sepsis in critically ill patients.
- Conditions
- Intra-Abdominal Infections, Intestinal Obstruction, Appendicitis Acute, Perforated Viscus
- Trial name
- CLI (NCT06901544)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Atrial Fibrillation (AF), Magnesium Sulfate
Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery
Atrial fibrillation (AF) is a common complication after cardiac surgery. Most studies suggest that the frequency ranges between 25-40%.
- Conditions
- Atrial Fibrillation (AF), Magnesium Sulfate, Post Cardiac Surgery Patients
- Trial name
- Magnesium AF (NCT06675500)
- Testing
- Magnesium sulphate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia
Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery
Research indicates that hypothyroidism decreases heart contractility, reduces stroke volume and rate, affects the vascular endothelium, and increases the risk of atherosclerosis, systemic vascular resistance, hypertension…
- Conditions
- Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia, Euthyroid Sick Syndrome, Cardiac Surgery Requiring Cardiopulmonary Bypass
- Trial name
- L-Thyroxine (NCT06660823)
- Testing
- L-thyroxine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Anaesthesia
Comparing Post-operative Analgesia After (PECS II) Block and (ESPB) in Modified Radical Mastectomy
The aim of this study is to compare the analgesic efficacies of the modified pectoral plane block (PECS II) and the erector spinae plane block (ESPB) after modified radical mastectomy surgery through assessment of post-operative…
- Trial name
- NCT06714682
- Testing
- Modified Pectoral Plane block group, Erector spinae plane block group.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University