Sleep QualityLISNCT06687304
Light in Healthcare Environment (Ljus i sjukhusmiljö)
A study testing Light enhancement in people with Sleep Quality and Well-being, run by Lund University at 3 sites in Sweden.
Trial summary
The goal of this clinical trial is to learn if light can enhance the feeling of well-being and sleep quality in Radiographers. It will also find out if there is an optimal recipe for light. Read more about this study
- Who is it for?
- Ages 21 years and olderHealthy volunteers can take part
- Conditions the study is for
- Sleep Quality, Well-being, Melatonin
- What is being tested?
- Light enhancement
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 18 participants
- Where
- 3 sitesSweden
- Study dates
- 15 Nov 2024to 31 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Radiographer
Who cannot join
- -
Trial locations and contacts
3 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Sweden3 sites, 3 recruiting
- Recruiting
Skånes universitetssjukhus Lund
Lund, Skåne County, 22242
Camilla Viseu, +46 705425698, camilla.viseu@med.lu.se
- Recruiting
Skånes universitetssjukhus
Malmö, Skåne County, 21428
Camilla Viseu, +46 705425698, camilla.viseu@med.lu.se
- Recruiting
Lasarettet Trelleborg
Trelleborg, Skåne County, 23155
Camilla Viseu, +46 705425698, camilla.viseu@med.lu.se
About this study
Official title: Benefits of Light in the Radiographic Environment
The goal of this clinical trial is to learn if light can enhance the feeling of well-being and sleep quality in Radiographers. It will also find out if there is an optimal recipe for light. The main questions it aims to answer are:
- Will alertness, energy levels, and sleep quality increase in radiographers when the lighting is differed?
- What light recipe is the most beneficial for the personnel? Researchers will compare no enhanced light environment to different enhanced light environment to see if the enhanced light is beneficial for radiographers.
Participants will:
- Will work in an enhanced light environment or a non-enhanced light environment
- Answer surveys
- Take saliva sample
Read the detailed description
The aim of this study is to examine the impact of different daylight lighting conditions in the radiographer's workplace environment. Will alertness, energy levels, well-being, and sleep quality increase in the personnel at the radiology department when the lighting is differed? Which light recipe is the most beneficial for the personnel at the radiology department? Method Design: In order to ascertain the light level that yields the desired effect, an quasi-experimental study design will be employed to identify the optimal light recipe with the appropriate light intensity. A crossover design is intended for implementation. This design approach offers the advantage of having each participant serve as their own control, thereby minimizing the potential impact of inter-group differences on the results. Furthermore, it enhances statistical efficiency, even with a reduced number of study participants (Lim \& In, 2021).
Context/recruitment: Recruitments of personnel from various radiology departments at Skåne University Hospital (SUS) in Lund are planned to be conducted. A total of 18 the personnel at the radiology department will be included during the darker months of the year. At 10 to 20 workstations, a floor lamp equipped with an adjusted light prescription will be installed. Participants will be assigned to conditions in which the lamp will either be activated with the specified light recipe or remain turned off. After a duration of two weeks, the conditions will be reversed for an additional two-week period. This process will be repeated using four different light recipes to evaluate their effects on the energy levels, activity, and sleep quality of the staff. The objective is to gather insights from each season that can be implemented in the subsequent winter to determine the optimal light level.
Data collection: Subjective Measurement Methods - Staff Surveys
General Survey Participants will be asked questions regarding their typical age and gender. Additionally, a modified version of the Morningness-Eveningness Questionnaire (MEQ) will be utilized to determine each individual;s chronotype (Adan \& Almirall, 1991). A Swedish translation of this questionnaire has proven effective in assessing chronotype and is appropriate for use when a shorter assessment tool is needed (Danielsson et al., 2019).
Karolinska Sleepiness Scale (KSS) To assess the level of alertness and energy among study participants, the KSS will be utilized. This scale employs a 9-point Likert format to evaluate perceived fatigue and energy levels (Åkerstedt \& Gillberg, 1990). The KSS has been utilized in various research studies to examine the impact of lighting conditions on perceived alertness.
Patient-Reported Outcomes Information System Short Form Sleep Disturbance 8a(PROMIS) The Patient-Reported Outcomes Measurement Information System (PROMIS) is an assessment tool designed to measure self-reported sleep disturbances, including sleep quality, difficulty falling asleep, and staying asleep. It consists of 8 items rated by patients to evaluate the frequency and severity of sleep issues, supporting clinical insights into sleep-related health impacts.
Furthermore, participants \& well-being will be quantified utilizing the WHO-5 Well-Being Index.
Objective Measurement Methods: Sleep Data via Activity Bands - Actiwatch
The employment of activity monitors allows for the objective measurement of sleep. The actigraphy device is worn on the non-dominant wrist and is non-invasive (Weiss et al., 2010). It continuously tracks the participant's movements and records sleep parameters including duration and quality. These measurements can subsequently be analyzed (Ancoli-Israel et al., 2015). Due to the impracticality of wearing these wristbands during working hours, participants will attach them to their clothing at work and wear them on their wrist after work hours.
Additionally, saliva samples will be collected to measure cortisol and melatonin levels in the study participants. Cortisol secretion is stimulated by dawn light or, in winter, often by office lighting. This secretion level provides an objective parameter for assessing activation. Conversely, melatonin secretion is suppressed by the light of dawn, and the extent of this inhibition serves as an indicator of the lights effectiveness.
- Conditions
- Sleep Quality, Well-being, Melatonin, Cortisol, Energy Levels
- Being tested
- Light enhancement
- Keywords
- Light, Radiography, Light environment, Circadian rhythm, Personnel at radiology departments
- Medical subject headings
- Sleep Initiation and Maintenance Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Light enhancementDevice
Also called Lamp, Light recipe, Dynamic lighting
Light recipe that mimics the varying daylight of the day
| Study group | Role | What they receive |
|---|---|---|
| Enhanced light environment | Active comparator | Not described Receives: Device: Light enhancement |
| Non-enhanced light environment | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Karolinska Sleepiness Scale (KSS)
To assess the subjective level of sleepiness at a particular time during the day
Measured: Measurements will be taken three times daily over a period of 16 to 20 weeks, depending on the start date of the inclusion phase, for each period.
WHO-5 Well-Being Index
To assess the level of well-being, the WHO-5 Well-Being Index is used. It's a brief, self-reported measure of current mental well-being, consisting of five questions that assess positive mood, vitality, and general interest over the past two weeks.
Measured: Measurements will be taken at the start and then second Friday in each two-week period over the 16 to 20 weeks (depending on when the inclusion phase can begin) during which inclusion occurs for each season.
PROMIS
Patient-Reported Outcomes Measurement Information System (PROMIS) is a standardized, self-reported questionnaire designed to measure an individual's perception of their sleep quality, specifically addressing issues like difficulty falling asleep, staying asleep, and feelings of restlessness. It consists of 8 items that gauge the severity of sleep disturbances over the past seven days.
Measured: Measurements will be taken at the start and then every Friday in each two-week period over the 16 to 20 weeks (depending on when the inclusion phase can begin) during which inclusion occurs for each season.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Nov 2024
- Study start15 Nov 2024
- Primary completion31 Mar 2027 (estimated)
- Study completion31 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Sleep QualityStudies of the same condition, open and under way.
- More trials run by Lund UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 18 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Lund University
- Sponsor type
- University, hospital or other
- Collaborators
- AFA Insurance
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06687304
- Sponsor's protocol ID
- 2024-04436-02
- Acronym
- LIS
- Status last verified
- Nov 2025
- First submitted
- 4 Nov 2024
- Last updated
- 2 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Weiss AR, Johnson NL, Berger NA, Redline S. Validity of activity-based devices to estimate sleep. J Clin Sleep Med. 2010 Aug 15;6(4):336-42.
PubMed 20726281Ancoli-Israel S, Martin JL, Blackwell T, Buenaver L, Liu L, Meltzer LJ, Sadeh A, Spira AP, Taylor DJ. The SBSM Guide to Actigraphy Monitoring: Clinical and Research Applications. Behav Sleep Med. 2015;13 Suppl 1:S4-S38. doi: 10.1080/15402002.2015.1046356. No abstract available.
PubMed 26273913
Study at a glance
From the registry record, last updated by the sponsor on 2 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Benefits of Light in the Radiographic Environment
- ClinicalTrials.gov ID
- NCT06687304
- Acronym / sponsor ID
- LIS / 2024-04436-02
- Conditions
- Sleep Quality, Well-being, Melatonin, Cortisol, Energy Levels
- Keywords
- Light, Radiography, Light environment, Circadian rhythm, Personnel at radiology departments
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 18 participants (estimated)
- Lead sponsor
- Lund UniversityUniversity, hospital or other
- Collaborators
- AFA Insurance
- Study start
- 15 Nov 2024 (actual)
- Primary completion
- 31 Mar 2027 (estimated)
- Study completion
- 31 Mar 2027 (estimated)
- First posted
- 13 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn if light can enhance the feeling of well-being and sleep quality in Radiographers. It will also find out if there is an optimal recipe for light. The main questions it aims to answer are:
- Will alertness, energy levels, and sleep quality increase in radiographers when the lighting is differed?
- What light recipe is the most beneficial for the personnel? Researchers will compare no enhanced light environment to different enhanced light environment to see if the enhanced light is beneficial for radiographers.
Participants will:
- Will work in an enhanced light environment or a non-enhanced light environment
- Answer surveys
- Take saliva sample
Detailed description
The aim of this study is to examine the impact of different daylight lighting conditions in the radiographer's workplace environment. Will alertness, energy levels, well-being, and sleep quality increase in the personnel at the radiology department when the lighting is differed? Which light recipe is the most beneficial for the personnel at the radiology department? Method Design: In order to ascertain the light level that yields the desired effect, an quasi-experimental study design will be employed to identify the optimal light recipe with the appropriate light intensity. A crossover design is intended for implementation. This design approach offers the advantage of having each participant serve as their own control, thereby minimizing the potential impact of inter-group differences on the results. Furthermore, it enhances statistical efficiency, even with a reduced number of study participants (Lim \& In, 2021).
Context/recruitment: Recruitments of personnel from various radiology departments at Skåne University Hospital (SUS) in Lund are planned to be conducted. A total of 18 the personnel at the radiology department will be included during the darker months of the year. At 10 to 20 workstations, a floor lamp equipped with an adjusted light prescription will be installed. Participants will be assigned to conditions in which the lamp will either be activated with the specified light recipe or remain turned off. After a duration of two weeks, the conditions will be reversed for an additional two-week period. This process will be repeated using four different light recipes to evaluate their effects on the energy levels, activity, and sleep quality of the staff. The objective is to gather insights from each season that can be implemented in the subsequent winter to determine the optimal light level.
Data collection: Subjective Measurement Methods - Staff Surveys
General Survey Participants will be asked questions regarding their typical age and gender. Additionally, a modified version of the Morningness-Eveningness Questionnaire (MEQ) will be utilized to determine each individual;s chronotype (Adan \& Almirall, 1991). A Swedish translation of this questionnaire has proven effective in assessing chronotype and is appropriate for use when a shorter assessment tool is needed (Danielsson et al., 2019).
Karolinska Sleepiness Scale (KSS) To assess the level of alertness and energy among study participants, the KSS will be utilized. This scale employs a 9-point Likert format to evaluate perceived fatigue and energy levels (Åkerstedt \& Gillberg, 1990). The KSS has been utilized in various research studies to examine the impact of lighting conditions on perceived alertness.
Patient-Reported Outcomes Information System Short Form Sleep Disturbance 8a(PROMIS) The Patient-Reported Outcomes Measurement Information System (PROMIS) is an assessment tool designed to measure self-reported sleep disturbances, including sleep quality, difficulty falling asleep, and staying asleep. It consists of 8 items rated by patients to evaluate the frequency and severity of sleep issues, supporting clinical insights into sleep-related health impacts.
Furthermore, participants \& well-being will be quantified utilizing the WHO-5 Well-Being Index.
Objective Measurement Methods: Sleep Data via Activity Bands - Actiwatch
The employment of activity monitors allows for the objective measurement of sleep. The actigraphy device is worn on the non-dominant wrist and is non-invasive (Weiss et al., 2010). It continuously tracks the participant's movements and records sleep parameters including duration and quality. These measurements can subsequently be analyzed (Ancoli-Israel et al., 2015). Due to the impracticality of wearing these wristbands during working hours, participants will attach them to their clothing at work and wear them on their wrist after work hours.
Additionally, saliva samples will be collected to measure cortisol and melatonin levels in the study participants. Cortisol secretion is stimulated by dawn light or, in winter, often by office lighting. This secretion level provides an objective parameter for assessing activation. Conversely, melatonin secretion is suppressed by the light of dawn, and the extent of this inhibition serves as an indicator of the lights effectiveness.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Enhanced light environment | Active comparator | Device: Light enhancement |
| Non-enhanced light environment | No intervention | – |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Radiographer
Key exclusion criteria (1 listed)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Light enhancementAlso: Lamp, Light recipe, Dynamic lightingLight recipe that mimics the varying daylight of the day | Device | Enhanced light environment |
Primary outcome
Karolinska Sleepiness Scale (KSS)
Time frame: Measurements will be taken three times daily over a period of 16 to 20 weeks, depending on the start date of the inclusion phase, for each period.
To assess the subjective level of sleepiness at a particular time during the day
WHO-5 Well-Being Index
Time frame: Measurements will be taken at the start and then second Friday in each two-week period over the 16 to 20 weeks (depending on when the inclusion phase can begin) during which inclusion occurs for each season.
To assess the level of well-being, the WHO-5 Well-Being Index is used. It's a brief, self-reported measure of current mental well-being, consisting of five questions that assess positive mood, vitality, and general interest over the past two weeks.
PROMIS
Time frame: Measurements will be taken at the start and then every Friday in each two-week period over the 16 to 20 weeks (depending on when the inclusion phase can begin) during which inclusion occurs for each season.
Patient-Reported Outcomes Measurement Information System (PROMIS) is a standardized, self-reported questionnaire designed to measure an individual's perception of their sleep quality, specifically addressing issues like difficulty falling asleep, staying asleep, and feelings of restlessness. It consists of 8 items that gauge the severity of sleep disturbances over the past seven days.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Dec 2025.
- Background: PubMed 20726281Weiss AR, Johnson NL, Berger NA, Redline S. Validity of activity-based devices to estimate sleep. J Clin Sleep Med. 2010 Aug 15;6(4):336-42.
- Background: PubMed 26273913Ancoli-Israel S, Martin JL, Blackwell T, Buenaver L, Liu L, Meltzer LJ, Sadeh A, Spira AP, Taylor DJ. The SBSM Guide to Actigraphy Monitoring: Clinical and Research Applications. Behav Sleep Med. 2015;13 Suppl 1:S4-S38. doi: 10.1080/15402002.2015.1046356. No abstract available.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
3 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Light enhancement in people with Sleep Quality and Well-being, run by Lund University at 3 sites in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 3 sites in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Pether Jildenstal, PhD (0046462220000, pether.jildenstal@med.lu.se), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Karolinska Sleepiness Scale (KSS) (time frame: Measurements will be taken three times daily over a period of 16 to 20 weeks, depending on the start date of the inclusion phase, for each period.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06687304, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Dec 2025.